Preventive effects of gender and metabolic syndrome in 40s on colorectal cancer by colonoscopy.

2020 ◽  
Vol 38 (4_suppl) ◽  
pp. 59-59
Author(s):  
Hyun-Soo KIM ◽  
Su Young Kim ◽  
Jung Kuk Lee
Keyword(s):  
Metabolic Syndrome ◽  
Past History ◽  
Conditional Logistic Regression ◽  
Age Groups ◽  
Preventive Effect ◽  
Conditional Logistic Regression Analysis ◽  
Hazard Ratios ◽  
History Of ◽  
One Year ◽  
Preventive Effects

59 Background: This study was aimed at measuring the preventive effect of colonoscopy for CRC development depending on age of index colonoscopy, gender and metabolic syndrome among persons aged 40 to 59 years. Methods: Between January 2005 and December 2006, data for the population aged from 40 to 59 who underwent colonoscopy (CSP cohort) claimed were collected from National Health Insurance Service (NHIS). Non-CSP (N-CSP) subjects were also collected by 1:5 propensity score matching with parameters of age, sex, and metabolic profiles, smoking, alcohol and past history of cancer. After one year of washout period, the risk of developing CRC was estimated by the occurrence of new case from January 2009 to December 2014 using the link of National CRC Registry to NHIS database. Compared with N-CSP cohort, hazard ratios (HRs) were obtained via conditional logistic regression analysis to estimate the risk of CRC in CSP cohort by age groups. Results: A total of 2,339,359 subjects were included (CSP cohort: 395,738 and matched N-CSP cohort: 1,943,621). The HRs for developing CRC by ages of 40-44, 45-49, 50-54, and 55-59 years in a CSP cohort were 0.864 ( P = NS), 0.591 ( P < 0.001), 0.599 ( P < 0.001), and 0.524 ( P < 0.001) in men, and 0.774 ( P = NS), 0.841 ( P = NS), 0.598 ( P < 0.001), and 0.605 ( P < 0.001) in women, respectively. Interestingly, when confined to patients with metabolic syndrome in their 40s, HRs for CRC in the colonoscopy cohort were statistically significantly lowered to 0.372 in early 40’s and 0.386 in men of late 40s, respectively, but not in women of 40s. Conclusions: The CRC prevention effect of colonoscopy is expected from late 40s in men and early 50s in women. Furthermore, in cases with metabolic syndrome, the preventive effect of colonoscopy is expected in men of early forties.

scholarly journals Demographic Profile of Patients with Metabolic Syndrome in Bangladeshi Population

1970 ◽  
Vol 22 (1) ◽  
pp. 36-42
Author(s):  
MM Rahman Khan ◽  
MA Jalil Chowdhury ◽  
M Zahirul Haque ◽  
MM Hoque Chowdhury ◽  
M Khalilur Rahman ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Leisure Time ◽  
Family Income ◽  
Past History ◽  
Age Groups ◽  
High Intake ◽  
Demographic Profile ◽  
The Metabolic Syndrome ◽  
History Of ◽  
Bangladeshi Population

This was a hospital based study done to see the demographic profile of patients with metabolic syndrome in Bangladesh. A total of 334 patients attending in medicine OPD BSMMU were included in this study. According to modified NCEP ATP III criteria 27.2% of subjects aged ≥ 20 years had the metabolic syndrome and it was more commonly seen in women than in men (32.4% vs 21.7%). The metabolic syndrome increased with age in both sexes (40-49 years age groups 24.2% to 50-59 years age groups 35.2%). The metabolic syndrome was also significantly associated with postmenopausal period, family income, leisure time exercise (<60 min/wk), low physical activity, self reported high intake of carbohydrate diet, presence of family history and past history of components of the metabolic syndrome. DOI: 10.3329/taj.v22i1.5018 TAJ 2009; 22(1): 36-42

scholarly journals Prevalence of Diastolic Dysfunction in Non Diabetic Patients of Metabolic Syndrome

2021 ◽  
Author(s):  
Kaushiki Kirty ◽  
Prabha Adhikari
Keyword(s):  
Metabolic Syndrome ◽  
Risk Factor ◽  
Diastolic Dysfunction ◽  
Strong Correlation ◽  
Past History ◽  
Diabetic Patients ◽  
Short Term ◽  
The Metabolic Syndrome ◽  
History Of

Abstract Background :The purpose of the present study was to study the prevalence of metabolic syndrome in non diabetic patients of metabolic syndrome Materials and Methods: 100 patients of non diabetic metabolic syndrome were screened using 2-D Echocardiogram.Results: 34% of non diabetic patients of metabolic syndrome had diastolic dysfunction, with no association found between the components of metabolic syndrome and diastolic dysfunction. There was a strong correlation between a past history of hypertension and dyslipidemia with diastolic dysfunction.Conclusion: Our findings suggest that long standing metabolic syndrome is a risk factor for diastolic dysfunction, rather than short term elevation of the metabolic syndrome parameters. Also it is likely that Diabetes and Prediabetes itself is responsible for most of the diastolic dysfunction that is seen in metabolic syndrome

scholarly journals SOS Teeth: First Priority Teeth with Advanced Caries and Its Associations with Metabolic Syndrome among a National Representative Sample of Young and Middle-Aged Adults

2020 ◽  
Vol 9 (10) ◽  
pp. 3170 ◽  
Author(s):  
Galit Almoznino ◽  
Ortal Kessler Baruch ◽  
Ron Kedem ◽  
Noam E. Protter ◽  
Boaz Shay ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Representative Sample ◽  
Parental History ◽  
Obstructive Sleep ◽  
History Of ◽  
Nationally Representative ◽  
One Year ◽  
Ischemic Attack ◽  
Middle Aged Adults ◽  
The Military

“SOS teeth” are defined as the first priority teeth for treatment, that have distinct cavitation reaching the pulp chamber or only root fragments are present. These are teeth with severe morbidity, that may require pulp capping, root canal treatment, or extraction, and therefore should be treated first. The study aims to explore whether or not a metabolic syndrome (MetS) is associated with SOS teeth. To that end, we performed across-sectional records-based study of a nationally representative sample of 132,529 military personnel aged 18–50 years, who attended the military dental clinics for one year. The mean number of SOS had no statistically significant association with: smoking (p = 0.858), alcohol consumption (p = 0.878), hypertension (p = 0.429), diabetes mellitus (p = 0.866), impaired glucose tolerance (p = 0.909), hyperlipidemia (p = 0.246), ischemic heart disease (p = 0.694), S/P myocardial infarction (p = 0.957), obstructive sleep apnea (p = 0.395), fatty liver (p = 0.074), S/P stroke (p = 0.589), and S/P transient ischemic attack (p = 0.095) and with parental history of: diabetes (p = 0.396)], cardiovascular disease (p = 0.360), stroke (p = 0.368), and sudden death (p = 0.063) as well as with any of the medical auxiliary examinations (p > 0.05). Cariogenic diet was positively associated with SOS teeth (p < 0.001). We conclude that SOS teeth had no statistically significant association with MetS components or with conditions that are consequences or associated with MetS. The only statistically significant parameter was a cariogenic diet, a well-known risk factor for caries and MetS.

FC13-04 - Suicide risk in relation to age and psychiatric hospitalization

2011 ◽  
Vol 26 (S2) ◽  
pp. 1885-1885
Author(s):  
J. Reutfors ◽  
L. Brandt ◽  
K. Sparring Björkstén ◽  
A. Ekbom ◽  
U. Ösby
Keyword(s):  
Suicide Risk ◽  
Psychiatric Hospitalization ◽  
Conditional Logistic Regression ◽  
Age Groups ◽  
The Elderly ◽  
Population Based ◽  
Age Group ◽  
Post Discharge ◽  
History Of ◽  
Control Study

IntroductionSuicide risk is increased in patients with a history of psychiatric hospitalization.AimTo explore how suicide risk varies by age during psychiatric hospitalization and in the year post-discharge.MethodsThis is a population-based case-control study of all suicides (n = 20,675; 70% male) in Sweden aged ≥18 years during 1991–2003. Each suicide was individually matched to 10 population controls by age, sex, and county of residence. Discharge diagnoses of a mental disorder (except dementia and other organic disorders) in the year prior to suicide were identified by register linkage. Odds ratios (OR) were calculated by conditional logistic regression to estimate the relative risk of suicide in those with psychiatric diagnoses compared to the general population. ORs were estimated by age group (18–34 years, 35–49 years, 50–64 years, and ≥ 65 years) and timing of the suicide in relation to discharge.ResultsDuring hospitalization, the youngest age group had the greatest suicide risk elevation [OR 64 (95% CI 44-92)]. In the first month post-discharge, the oldest age group had the highest suicide risk elevation [OR 162 (95% 66–399) in the first week and OR 127 (95% 67–242) in the second to fourth weeks]. In the remaining eleven months, suicide risk elevation was lower and relatively similar in different age groups.ConclusionsDuring the year following psychiatric hospitalization, an especially high attention should be paid to the suicide risk of the elderly patients in the first month post-discharge.

scholarly journals Surgical Management of Bicornual Uterine Prolapse in a Siamese Cat: A Case Report

2020 ◽  
pp. 320-323
Keyword(s):  
Surgical Management ◽  
Uterine Prolapse ◽  
Past History ◽  
Rare Condition ◽  
Operative Management ◽  
Visual Examination ◽  
Siamese Cat ◽  
History Of ◽  
One Year ◽  
Veterinary Hospital

Uterine prolapse is a rare condition in cats that can be managed by performing either an external hysterectomy or manual reduction followed by ovariohysterectomy. This article describes surgical management of bilateral uterine prolapse in a queen. A one year old female, pluriparous Siamese cat (Felis catus) with no past history of dystocia and weighing 2.8 kg was presented to Andys Veterinary hospital, Nairobi, Kenya with a protruding mass through the vulval. The queen had a history of recent queening and had delivered three kittens a week earlier. The owner noticed the protruding mass about 24 hours after the delivery of the last neonate. A few days later, the cat was not suckling the kittens well and was in appetent. As a sequel to this, two kittens died. After a week, the protruding mass had a pungent smell and the client presented the cat to the hospital. Complete bilateral uterine prolapse was diagnosed after a visual examination and palpation of the mass. The uterus was swollen, had necrotic areas and debris. Accordingly, a two staged ovariohysterectomy was opted for to manage the case. An internal ovariectomy was first done via a ventral midline celiotomy followed by an external hysterectomy. Post-operative management included pain medication and antibiotic therapy and the patient recovered well and was discharged after 2 days. The skin sutures were removed 10 days postoperatively. The cat recovered uneventfully with no further complications reported by the owner. In conclusion, this article shows that when the prolapsed uterus is swollen, damaged and necrotic, a two staged ovariohysterectomy should be the method of treatment and the outcome is good despite the duration of the condition.

scholarly journals Hydatid disease with Aspergilloma: A unique case report

2021 ◽  
Vol 91 (1) ◽  
Author(s):  
Sandeep Sharma ◽  
Parikshit Thakare ◽  
Ketaki Utpat ◽  
Unnati Desai
Keyword(s):  
Case Report ◽  
Hydatid Disease ◽  
Past History ◽  
Case Reports ◽  
Unique Case ◽  
Rare Finding ◽  
History Of ◽  
One Year

The coexisting presence of hydatid disease with aspergillus colonization is a rare finding. The 20-year-old presented with symptoms of hemoptysis with past history of tuberculosis. On further evaluation, the patient was diagnosed as a case of aspergilloma and managed conservatively. After one year of presenting with similar complaints, the patient was turned out to be hydatid disease with aspergillus colonization on the basis of clinic-radiological and bronchoscopic evaluation. Till now only a few case reports have been reported. We report a unique case report of a similar presentation.

scholarly journals Age-specific diabetes risk by the number of metabolic syndrome components: a Korean nationwide cohort study

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Min-Kyung Lee ◽  
Kyungdo Han ◽  
Hyuk-Sang Kwon
Keyword(s):  
Metabolic Syndrome ◽  
Incidence Rates ◽  
Diabetes Risk ◽  
South Korean ◽  
Hazard Ratios ◽  
Increased Risk ◽  
History Of ◽  
Korean National Health Insurance ◽  
Study Participants ◽  
Metabolic Syndrome Components

Abstract Background Metabolic syndrome is associated with an increased risk of diabetes. This study investigated the associations between the number of metabolic syndrome components and diabetes risk by age, sex and BMI. Methods Data for 19,475,643 participants ≥ 20 years old with no history of diabetes were obtained between 2009 and 2012 and were accessed using the South Korean National Health Insurance Service. Metabolic syndrome was defined according to the modified criteria of the National Cholesterol Education Program Adult Treatment Panel III. We assessed the risk of diabetes according to the number of metabolic syndrome components after stratifying the study participants into groups by age (20–39, 46–64, ≥ 65 years), sex, and BMI (below or above 25). Results During an average of 5.13 years of follow-up, the incidence rates of diabetes increased with the number of metabolic syndrome components. Age and BMI gradually increased with the number of metabolic syndrome components. The multivariable-adjusted hazard ratios (HRs) for incident diabetes were 1.401, 1.862, 2.47, 3.164 and 4.501 for participants with one through five components, respectively, compared with those without metabolic syndrome components. The risk of diabetes was 1.79-, 2.18-, and 3.05-times higher for participants ≥ 65 years; 2.57-, 3.45-, and 5.18-times higher for participants 40–64 years; and 2.55-, 3.89-, and 6.31-times higher for participants 20–39 years of age with three through five components, respectively, compared to those with no components. There was no difference in the risk of diabetes between men and women. The HRs were 5.63 for participants with a BMI ≥ 25 and 3.98 for those with a BMI < 25 among individuals with five components. Conclusions The risk of diabetes was more strongly associated with the number of metabolic syndrome components among younger adults. In addition, the risk of diabetes across the number of metabolic syndrome components was greater in participants with a BMI ≥ 25.

PREVALENCE OF OSTEOPOROSIS IN SUB-URBAN POPULATION OF CHENNAI USING QUS (QUANTITATIVE ULTRASOUND) OF CALCANEUM -A CROSS SECTIONAL STUDY

2021 ◽  
pp. 43-44
Author(s):  
S. Balameena ◽  
R Agavendra ◽  
Karthikeyan Karthikeyan ◽  
Sujatha Sujatha ◽  
Sabarish Sabarish ◽  
...  
Keyword(s):  
Screening Test ◽  
Past History ◽  
Age Groups ◽  
Cost Effective ◽  
Cross Sectional Study ◽  
Health Concern ◽  
Cross Sectional ◽  
Study Results ◽  
History Of ◽  
Ultrasound Score

Background:Burden of Osteoporosis and its related fractures are enormous and growing public health concern. Worldwide, an estimated 200 million adults suffer from osteoporosis. Vertebral and non-vertebral fractures are the most clinically relevant osteoporotic fracture because they are expensive to treat and have severe consequences for middle aged and elderly population.(1 ,2) The purpose of our study was to assess calcaneal ultrasound score as a screening test for osteoporosis. Material and Methods: Fifty patients above the age of 40 years who attended a health checkup camp conducted by our institute in a suburban population base of Chennai,Tamilnadu was subjected for noninvasive QUS of calcaneum bone as a screening test for osteoporosis. They were divided into different age groups ,co-morbid conditions noted and BMD scores from QUS was assessed. Statistical method were used with SPSS Version .It was a cross sectional descriptive study. Results: A total of 50 patients underwent QUS of calcaneum bone in our study , all of them above the age of 40 years. 33(66%) of them were females and 17(34%) were males. Eight patients( 16% ) had T score < -2.5 out of which 1 was male. 26 patients(52%) had T scores in the osteopenic range (-1>Tscore>-2.5).16 patients(32%) had T scores in the normal range. 40 % of patients had associated osteoarthritis and four patients had diabetes. 2 patients who underwent screening had past history of nontraumatic fractures. Conclusion: QUS of calcaneum is a good screening tool for assessing bone density in our country since its cost effective and can be used in various screening camps. The machine is portable and can be used with minimal training making it easier for the primary caregiver. It has reasonably good sensitivity and fair specicity when using Tscore of -2.5 as the cut off point. However DEXAis the gold standard for treatment and followup of patients with osteoporosis.

scholarly journals Sudden Death and Epilepsy

2005 ◽  
Vol 5 (6) ◽  
pp. 223-224 ◽  
Author(s):  
Elinor Ben-Menachem
Keyword(s):  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Geographic Location ◽  
Case Control ◽  
Related Phenomenon ◽  
Unexpected Death ◽  
Conditional Logistic Regression Analysis ◽  
History Of ◽  
Clonic Seizures ◽  
Control Study

Case–control Study of SUDEP Langan Y, Nashef L, Sander JW Neurology 2005;64:1131–1133 Purpose To examine the influence of various factors on the risk of sudden unexpected death in epilepsy (SUDEP). Methods The authors investigated 154 cases in which a postmortem examination was performed. Each case had four controls with epilepsy from the community, matched for age and geographic location. Backward stepwise conditional logistic regression analysis was performed, and odds ratios for risk and protection were determined. Results The risk of SUDEP was increased with a history of generalized tonic–clonic seizures in the previous 3 months (odds ratio [OR]: 13.8; 95% CI: 6.6 to 29.1). The presence of supervision at night was found to be protective (OR: 0.4; 95% CI: 0.2 to 0.8) when a supervising individual shared the same bedroom or when special precautions such as a listening device were used (OR: 0.1; 95% CI: 0.0 to 0.3). Conclusions This work lends support to the view that SUDEP is a seizure-related phenomenon and that control of tonic–clonic seizures is important in its prevention. Nocturnal supervision seems to protect against SUDEP.

Efficacy of bupropion for smoking cessation in smokers with a former history of major depression or alcoholism∗

1999 ◽  
Vol 174 (2) ◽  
pp. 173-178 ◽  
Author(s):  
Kara E. Hayford ◽  
Christi A. Patten ◽  
Teresa A. Rummans ◽  
Darrell R. Schroeder ◽  
Kenneth P. Offord ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Depressive Symptoms ◽  
Major Depression ◽  
Past History ◽  
Initial Period ◽  
Smoking Abstinence ◽  
End Of Treatment ◽  
History Of ◽  
One Year ◽  
Dose Response Effect

BackgroundA past history of major depression or alcoholism has been associated with poorer smoking treatment outcomes.AimTo evaluate the efficacy of bupropion for smoking cessation in smokers with a former history of major depression or alcoholism, and changes in depressive symptoms during smoking abstinence.MethodData were drawn from a multicentre trial of bupropion for smoking cessation. Smokers (n=615) received placebo or bupropion sustained-release at 100, 150, or 300 mg/day for six weeks after target quit date (TQD). The primary outcome was the point prevalence smoking abstinence at the end of treatment and at one year. The Beck Depression Inventory (BDI) was used to assess depressive symptoms.ResultsA significant dose – response effect of bupropion for smoking cessation was found. This was independent of history of major depression or alcoholism. Among those continuously abstinent from smoking for two weeks following TQD, an increase in BDI score was associated with a return to smoking at end of treatment.ConclusionsBupropion is efficacious for smoking cessation independently of a former history of major depression or alcoholism. Increases in depressive symptoms during an initial period of abstinence are associated with a return to smoking.

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