scholarly journals Case-Control Study of Diet, Cooking Methods and Colorectal Cancer In Viet Nam

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 22s-22s
Author(s):  
N. Tuan ◽  
L. Giang ◽  
L. Ngoan
Keyword(s):  
Colorectal Cancer ◽  
Case Control Study ◽  
Positive Association ◽  
Case Control ◽  
Cooking Methods ◽  
Viet Nam ◽  
Food Frequency ◽  
Increased Risk ◽  
Underlying Mechanisms ◽  
Control Study

Background: Colorectal cancer is one of the most common cancers and the leading cause of death in the world and the third most common cancer in Viet Nam. Aim: To examine the association between diet, cooking methods and the risk of colorectal cancer by a case-control study in the Hanoi city, Viet Nam. Methods: A case-control study was designed. Case was newly incident colorectal cancer (125 cases). Control was hospital-based case without any cancer and matched to case by sex and +/− 5 years old admitted to the same Bach Mai hospital in Hanoi city. Case to control ratio was one. Data collection was performed by face to face interviewed by the trained interviewers in using the validated semiquantitative food frequency and demographic and lifestyle questionnaires. Food frequency intake inquired about a frequent intake per day, per week, per month or per year for 85 items of fruit, vegetables, fishes, meats, salted foods, bean and nuts; lightly browned, medium browned, high browned, well browned, and blackened/charred of cooking meat and fishes. Multivariable adjusted odds ratio and 95% confidence interval (OR, 95% CI) was estimated using STATA 10.0. Results: The significant increased risk of colorectal cancer was observed for a high frequent intake of fried meat (OR=2.63, 95% CI: 1.47-4.66); fried soya cheese (OR=2.00, 95% CI: 1.05-3.80); grilled food (OR=3.18, 95% CI: 1.84-5.48); roasted food (OR=3.56, 95% CI: 2.05-6.20); beef (OR=2.06, 95% CI: 1.17-3.83); eat salty food (OR=1.71, 95% CI: 1.03-2.82); instant noodle (OR=3.08, 95% CI: 1.61-5.91); salted vegetable (OR=1.63, 95% CI: 1.01-2.73); smoking (OR=5.5, 95% CI: 1.90-15.96). In contrast, a significant decreased risk of colorectal cancer was seen for a high frequent intake of soymilk (OR=0.45, 95% CI: 0.24-0.87); sweet leaf (OR=0.28, 95% CI: 0.13-0.60); guava (OR=0.55, 95% CI: 0.32-0.94); orange (OR=0.15, 95% CI: 0.07-0.36). Conclusion: We observed the positive association between cooking methods and the risk of colorectal cancer. Further study of the underlying mechanisms of cooked meat and fish is highly recommended in Viet Nam.

scholarly journals Association between phytosterol intake and colorectal cancer risk: a case–control study

2017 ◽  
Vol 117 (6) ◽  
pp. 839-850 ◽  
Author(s):  
Jing Huang ◽  
Ming Xu ◽  
Yu-Jing Fang ◽  
Min-Shan Lu ◽  
Zhi-Zhong Pan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Chinese Population ◽  
Case Control Study ◽  
Positive Association ◽  
Case Control ◽  
Colorectal Cancer Risk ◽  
Inverse Association ◽  
Increased Risk ◽  
Control Study

AbstractA study in rodent models showed that phytosterols protected against colon carcinogenesis, probably by inhibiting dysregulated cell cycle progression and inducing cellular apoptosis. However, epidemiological studies on the relationship between phytosterols and colorectal cancer risk are quite limited. The aim of this study was to investigate dietary phytosterol intake in relation to colorectal cancer risk in the Chinese population. A case–control study was conducted from July 2010 to June 2016, recruiting 1802 eligible colorectal cancer cases plus 1813 age (5-year interval) and sex frequency-matched controls. Dietary information was collected by using a validated FFQ. The OR and 95 % CI of colorectal cancer risk were assessed by multivariable logistic regression models. A higher total intake of phytosterols was found to be associated with a 50 % reduction in colorectal cancer risk. After adjusting for various confounders, the OR of the highest quartile intake compared with the lowest quartile intake was 0·50 (95 % CI 0·41, 0·61, Ptrend<0·01) for total phytosterols. An inverse association was also found between the consumption of β-sitosterol, campesterol, campestanol and colorectal cancer risk. However, stigmasterol intake was related to an increased risk of colorectal cancer. No statistically significant association was found between β-sitostanol and colorectal cancer risk. Stratified analysis by sex showed that the positive association of stigmasterol intake with colorectal cancer risk was found only in women. These data indicated that the consumption of total phytosterols, β-sitosterol, campesterol and campestanol is inversely associated with colorectal cancer risk in a Chinese population.

scholarly journals Association between shiftwork and the risk of colorectal cancer in females: a population-based case–control study

2018 ◽  
Vol 75 (5) ◽  
pp. 344-350 ◽  
Author(s):  
Wa Mwenga Walasa ◽  
Renee N Carey ◽  
Si Si ◽  
Lin Fritschi ◽  
Jane S Heyworth ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Early Morning ◽  
Population Based ◽  
Case Control ◽  
Colorectal Cancer Risk ◽  
Adverse Health Outcomes ◽  
Increased Risk ◽  
Control Study

ObjectiveResearch indicates that shiftwork may be associated with increased risks of adverse health outcomes, including some cancers. However, the evidence of an association between shiftwork and colorectal cancer risk is limited and inconclusive. Further, while several possible pathways through which shiftwork might result in cancer have been proposed, few studies have taken these factors into account. We investigated the association between two types of shiftwork (graveyard shiftwork and early-morning shiftwork) and six mechanistic shiftwork variables (including light at night and phase shift) and the risk of colorectal cancer among females in an Australian population-based case–control study. Graveyard shiftwork was the primary exposure of interest.MethodsParticipants (350 cases and 410 controls) completed a lifetime occupational history, and exposure to each of the eight shiftwork variables was assigned to participants through a job exposure matrix. We used logistic regression to calculate odds ratios (OR) and corresponding 95% confidence intervals (CI) for the association between different shiftwork variables and the risk of colorectal cancer, adjusting for potential demographic, lifestyle and medical confounders.ResultsWorking in an occupation involving long-term exposure (>7.5 years) to graveyard shiftwork was not associated with colorectal cancer risk (adjusted OR 0.95, 95% CI 0.57 to 1.58). Similarly, no increased risks of colorectal cancer were seen for any of the other seven shiftwork variables examined.ConclusionsNo evidence of an increased risk of colorectal cancer among females who had worked in occupations involving shiftwork was observed in this study.

scholarly journals Malnutrition and Increased Risk of Adverse Outcomes in Elderly Patients Undergoing Elective Colorectal Cancer Surgery: A Case-Control Study Nested in a Cohort

Nutrients ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 207
Author(s):  
Cristina Martínez-Escribano ◽  
Francisco Arteaga Moreno ◽  
Marcos Pérez-López ◽  
Cristina Cunha-Pérez ◽  
Ángel Belenguer-Varea ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Older Adults ◽  
Hospital Admission ◽  
Case Control Study ◽  
Elective Surgery ◽  
Case Control ◽  
Nutritional Risk ◽  
Severe Malnutrition ◽  
Increased Risk ◽  
Control Study

Background: Malnutrition increases worse outcomes during hospital admission for elective colorectal cancer (CRC) surgery in older adults. Methods: This work was designed an observational, monocentric, case-control study nested in a cohort of patients undergoing elective surgery for CRC disease at the Hospital Universitario de la Ribera (HULR) (Alzira, Valencia, Spain) between 2011 and 2019. The study considered patients with a CONUT score in the range of moderate to severe malnutrition (>4 points), with control patients with normal nutritional situations or mild malnutrition. Results: Moderate-to-severe malnutrition cases presented a greater length of stay (LOS), a higher incidence of adverse events (both medical and surgical complications), a higher incidence of surgical-wound infection, a greater need for blood transfusion, and a greater amount of transfused packed red blood cells. During hospitalization, the percentage of patients without nutritional risk decreased from 46 to 9%, and an increase in mild, moderate, and severe risk was observed. Patients with severe nutritional risk at hospital admission had significantly increased mortality at 365 days after discharge (HR: 2.96 (95% CI 1.14–7.70, p = 0.002)). After adjusting for sex, age, and Charlson index score, patients with severe nutritional risk at admission maintained a higher mortality risk (HR: 3.08 (95% CI 1.10–8.63, p = 0.032)). Conclusion: Malnutrition prevalence is high in older adults undergoing CRC elective surgery. Furthermore, this prevalence increases during hospital admission. Malnutrition is linked to worse outcomes, such as LOS, surgical and clinical complications, and mortality. For this reason, nutritional interventions are very important in the perioperative period

scholarly journals Use of antibiotics and colorectal cancer risk: a primary care nested case–control study in Belgium

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e053511
Author(s):  
Johannes Van der Meer ◽  
Pavlos Mamouris ◽  
Vahid Nassiri ◽  
Bert Vaes ◽  
Marjan van den Akker
Keyword(s):  
Colorectal Cancer ◽  
General Practice ◽  
Cancer Risk ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Colorectal Cancer Risk ◽  
Oral Antibiotics ◽  
Increased Risk ◽  
Control Study

ObjectivesTo examine the association between the use of oral antibiotics and subsequent colorectal cancer risk.DesignMatched case–control study.SettingGeneral practice centres participating in the Integrated Computerised Network database in Flanders, Belgium.ParticipantsIn total, 1705 cases of colorectal cancer diagnosed between 01 January 2010 and 31 December 2015 were matched to 6749 controls by age, sex, comorbidity and general practice centre.Primary outcome measureThe association between the number of prescriptions for oral antibiotics and the incidence of colorectal cancer over a period of 1–10 years, estimated by a conditional logistic regression model.ResultsA significantly increased risk of colorectal cancer (OR 1.25, 95% CI 1.10 to 1.44) was found in subjects with one or more prescriptions compared with those with none after correction for diabetes mellitus. No dose-response relationship was found.ConclusionsThis study resulted in a modestly higher risk of having colorectal cancer diagnosed after antibiotic exposure. The main limitation was missing data on known risk factors, in particular smoking behaviour. This study did not allow us to examine the causality of the relationship, indicating the need of further investigation.

scholarly journals Environmental and Occupational Risk Factors of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study

2020 ◽  
Vol 17 (8) ◽  
pp. 2882 ◽  
Author(s):  
Tommaso Filippini ◽  
Marina Tesauro ◽  
Maria Fiore ◽  
Carlotta Malagoli ◽  
Michela Consonni ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Environmental Exposure ◽  
Case Control Study ◽  
Positive Association ◽  
Population Based ◽  
Case Control ◽  
Occupational Factors ◽  
Increased Risk ◽  
Control Study ◽  
Lateral Sclerosis

Objectives: Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease with still unknown etiology. We aimed at investigating the association between environmental and occupational factors with ALS risk. Methods: We performed a population-based case-control study in four Italian provinces (Catania, Modena, Novara, and Reggio Emilia) by administration of tailored questionnaires to ALS cases (n = 95) and randomly selected population referents (n = 135). We estimated ALS risk by calculating the odds ratio (OR) with its 95% confidence interval (CI) using an unconditional logistic regression model. Results: We found a positive association with disease risk for history of occupation in the agricultural sector (OR = 2.09, 95% CI 0.79–7.54), especially for longer than 10 years (OR = 2.72, 95% 1.02–7.20). Overall occupational exposure to solvents also suggested a positive association, especially for thinners (OR = 2.27, 95% CI 1.14–4.54) and paint removers (OR = 2.01, 95% CI 0.90–4.48). Both occupational and environmental exposure to electromagnetic fields show a slightly increased risk with OR = 1.69 (95% CI 0.70–4.09) and 2.41 (95% CI 1.13–5.12), respectively. Occupational but not environmental exposure to pesticides (OR = 1.22, 95% CI 0.63–2.37), particularly fungicides, and exposure to metals (OR = 4.20, 95% CI 1.88–9.38), particularly lead, mercury, and selenium, showed an imprecise but positive association. Finally, there was an indication of increased risk for living in proximity to water bodies. Conclusions: Despite the caution that needs to be used due to some study limitations, such as the low number of exposed subjects and the possibility of recall bias, these results suggest the potential role of some environmental and occupational factors in ALS etiology.

scholarly journals Association of Dietary Inflammatory Index (DII) With the Risk of Poly Cystic Ovary Syndrome: a Case-control Study

2021 ◽  
Author(s):  
Parivash Kavei ◽  
Esmaeil Yousefi Rad ◽  
Soheila Akbari ◽  
Ebrahim Falahi ◽  
Mahnaz Mardani ◽  
...  
Keyword(s):  
Energy Intake ◽  
Case Control Study ◽  
Positive Association ◽  
Case Control ◽  
Control Group ◽  
P Value ◽  
Dietary Inflammatory Index ◽  
Inflammatory Index ◽  
Increased Risk ◽  
Control Study

Abstract Objective: The aim of this case-control study was to investigate the association between Dietary Inflammatory Index (DII) and PCOS risk in the 120 newly-diagnosed cases of PCOS and 120 healthy controls aged between 18-45 years in Khorramabad of Iran. Results: Energy intake was significantly more in PCOS patients (p=0.01) and these people were less active than control women (p=0.001). The mean ± SD of DII in PCOS patients was 0.4±2.09 while it was 0.45±1.92 in control group (p=0.001). There was a positive association between increasing DII score and the risk of PCOS with the OR of 2.41(1.15, 5.02) in the crude model when we compared the fourth quartile with the lowest one. This association was still significant in several models after adjusting for age and energy intake in the model 1 (P- value for trend=0.001), in the second model and after adjusting for the level of activity, education, and family history of PCOS along with the first model (P- value for trend 0.003), and finally after additional adjustment for BMI in model 3 (P- value for trend 0.003). Results of present study showed that consuming more pro-inflammatory diets with higher DII scores are associated with increased risk of PCOS.

scholarly journals Energy-dense nutrient-poor snacks and risk of non-alcoholic fattyliver disease: a case-control study in Iran

2020 ◽  
Author(s):  
zahra yari ◽  
Makan Cheraghpour ◽  
Vahideh Aghamohammadi ◽  
Meysam Alipour ◽  
Nila Ghanei ◽  
...  
Keyword(s):  
Total Energy ◽  
Case Control Study ◽  
Positive Association ◽  
Case Control ◽  
Alcoholic Fatty Liver ◽  
Food Frequency ◽  
Relative Odds ◽  
Fourth Quartile ◽  
Alcoholic Fatty Liver Disease ◽  
Control Study

Abstract Objective: The purpose of the present study was to determine the association between energy-dense nutrient-poor snacks intake and the risk of non-alcoholic fatty liver disease (NAFLD) in Iranian adults. For this purpose, a total of 143 cases with a newly confirmed diagnosis of NAFLD and 471 controls free of the disease were studied. Dietary intake was assessed using a food frequency questionnaire.Results: The percentage of calories from total energy-dense nutrient-poor snacks was 6.08% and 5.04%, in patients and controls, respectively (p=0.036). Compared with subjects in the lowest quartile of total energy-dense nutrient-poor snacks intake, the risk of NAFLD for those in the top quartile of consumption increased by about two times, in both crude (OR:1.94; 95% CIs: 1.16-3.26; P for trend=0.015) and adjusted (OR:2.27; 95%CIs: 1.19-4.31; P for trend=0.001) models. The relative odds of NAFLD increased significantly in the fourth quartile of dietary cake and biscuit (OR: 1.21, P for trend=0.037) and soft drinks (OR: 1.64, P for trend=0.005) intake compared with the lowest corresponding quartiles, after adjustment for age, sex, body mass index, physical activity, alcohol, energy intake. Our results indicate that there might be a moderate positive association between energy-dense nutrient-poor snacks intake and risk of NAFLD.

Tu1413 Increased Risk of Advanced Serrated Polyps and Colorectal Cancer in Patients With Serrated Polyposis: an Observational Case- Control Study

2014 ◽  
Vol 79 (5) ◽  
pp. AB530
Author(s):  
Estanislao J. GóMez ◽  
Lisandro Pereyra ◽  
Raquel GonzáLez ◽  
Carolina Fischer ◽  
José M. Mella ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Serrated Polyps ◽  
Increased Risk ◽  
Control Study

scholarly journals Inflammatory potential of diet and risk of colorectal cancer: a case–control study from Italy

2015 ◽  
Vol 114 (1) ◽  
pp. 152-158 ◽  
Author(s):  
Nitin Shivappa ◽  
Antonella Zucchetto ◽  
Maurizio Montella ◽  
Diego Serraino ◽  
Susan E. Steck ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Rectal Cancer ◽  
Case Control Study ◽  
Continuous Variable ◽  
Case Control ◽  
Logistic Regression Models ◽  
Inflammatory Index ◽  
Colon And Rectal Cancer ◽  
Increased Risk ◽  
Control Study

Diet and inflammation have been suggested to be important risk factors for colorectal cancer (CRC). In the present study, we examined the association between the dietary inflammatory index (DII) and the risk of CRC in a multi-centre case–control study conducted between 1992 and 1996 in Italy. The study included 1225 incident colon cancer cases, 728 incident rectal cancer cases and 4154 controls hospitalised for acute non-neoplastic diseases. The DII was computed based on dietary intake assessed using a validated seventy-eight-item FFQ that included assessment of alcohol intake. Logistic regression models were used to estimate the OR adjusted for age, sex, study centre, education, BMI, alcohol drinking, physical activity and family history of CRC. Energy intake was adjusted using the residual method. Subjects with higher DII scores (i.e. with a more pro-inflammatory diet) had a higher risk of CRC, with the DII being used both as a continuous variable (ORcontinuous 1·13, 95 % CI 1·09, 1·18) and as a categorical variable (ORquintile 5 v. 1 1·55, 95 % CI 1·29, 1·85; P for trend < 0·0001). Similar results were observed when the analyses were carried out separately for colon and rectal cancer cases. These results indicate that a pro-inflammatory diet is associated with an increased risk of CRC.

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