Antibiotic Residues in Muscle Tissues of Edible Animal Products

2016 ◽  
pp. 267-366
Keyword(s):  
Antibiotic Residues ◽  
Animal Products ◽  
Muscle Tissues

scholarly journals Monitoring of Antibiotic Residues in Chicken Meat, Cow and Buffalo Milk Samples in Nepal

2020 ◽  
Vol 8 (3) ◽  
pp. 355-362
Author(s):  
Tulsi Ram Gompo ◽  
Ramchandra Sapkota ◽  
Manita Subedi ◽  
Pragya Koirala ◽  
Pragya Koirala ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Buffalo Milk ◽  
Chicken Meat ◽  
Antibiotic Residues ◽  
Maximum Residue Limit ◽  
Cross Sectional ◽  
Animal Products ◽  
Milk Samples ◽  
Meat Samples ◽  
Antibiotic Residue

In animal products, antibiotic residue is a serious concern for public health in the Himalayan nation, Nepal. A cross-sectional study on antibiotic residues in chicken meat, milk samples of cows, and buffaloes was conducted in selected districts of different provinces of Nepal. Altogether 126 chicken meat samples, 42 each from Kailali (Farwestern Province), Kaski (Gandaki Province), and Nuwakot (Bagmati Province) districts were tested for tetracycline, sulphonamides, penicillin, gentamicin, streptomycin residues by the ELISA method. At Kaski district approximately 57 % (24/42), 50 % (21/42) and 83% (35/42) of meat samples were tested positive for gentamicin (mean-ppb:11.5 μg/Kg/L), tetracycline (mean-ppb:1.44 μg/Kg/L), and fluoroquinolones (mean-ppb: 11.46 μg/ Kg/L) residues respectively. In Kailali and Nuwakot district, 48% (20/42) and 50 % (21/ 42) of meat samples deemed positive for sulphonamides (mean-ppb:15.9 μg/ Kg/L) and penicillin (mean-ppb: 0.39 μg/ Kg/L) residues, respectively. Of the total 168 tests performed in milk samples from Kavre district, 55% (93/168) of the milk samples were tested positive to antibiotic residues for gentamicin, streptomycin, and sulphonamides. The chicken meat samples had antibiotic residues within the national maximum residue limit (MRL); however, milk samples exceeded the national MRL for sulphonamides residues (mean-ppb: 26.44 μg/ Kg/L). The effective surveillance for antibiotic residues in animal products should be implemented strictly in Nepal. Int. J. Appl. Sci. Biotechnol. Vol 8(3): 355-362

scholarly journals A Cylindrical Molding Method for the Biofabrication of Plane-Shaped Skeletal Muscle Tissue

Micromachines ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 1411
Author(s):  
Minghao Nie ◽  
Ai Shima ◽  
Kenta Fukushima ◽  
Yuya Morimoto ◽  
Shoji Takeuchi
Keyword(s):  
Skeletal Muscle ◽  
Muscle Tissue ◽  
Myogenic Differentiation ◽  
Skeletal Muscle Tissue ◽  
Differentiation Markers ◽  
Animal Products ◽  
Molding Method ◽  
Muscle Tissues ◽  
Central Pillar

Muscle tissues can be fabricated in vitro by culturing myoblast-populated hydrogels. To counter the shrinkage of the myoblast-populated hydrogels during culture, a pair of anchors are generally utilized to fix the two ends of the hydrogel. Here, we propose an alternative method to counter the shrinkage of the hydrogel and fabricate plane-shaped skeletal muscle tissues. The method forms myoblast-populated hydrogel in a cylindrical cavity with a central pillar, which can prevent tissue shrinkage along the circumferential direction. By eliminating the usages of the anchor pairs, our proposed method can produce plane-shaped skeletal muscle tissues with uniform width and thickness. In experiments, we demonstrate the fabrication of plane-shaped (length: ca. 10 mm, width: 5~15 mm) skeletal muscle tissue with submillimeter thickness. The tissues have uniform shapes and are populated with differentiated muscle cells stained positive for myogenic differentiation markers (i.e., myosin heavy chains). In addition, we show the assembly of subcentimeter-order tissue blocks by stacking the plane-shaped skeletal muscle tissues. The proposed method can be further optimized and scaled up to produce cultured animal products such as cultured meat.

scholarly journals Worldwide Traceability of Antibiotic Residues from Livestock in Wastewater and Soil: A Systematic Review

Animals ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 60
Author(s):  
Lizbeth E. Robles-Jimenez ◽  
Edgar Aranda-Aguirre ◽  
Octavio A. Castelan-Ortega ◽  
Beatriz S. Shettino-Bermudez ◽  
Rutilio Ortiz-Salinas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Descriptive Analysis ◽  
Animal Production ◽  
Antibiotic Residues ◽  
Environmental Matrices ◽  
Growth Promoters ◽  
Negative Effects ◽  
Animal Products ◽  
Terrestrial Animal ◽  
America South

The use of antibiotics in animal production are widely used for disease treatment, health protection, and as growth promoters. Common antibiotics used in veterinary medicine are excreted and eliminated through the sewage system, contaminating water and soil with negative effects on agricultural activities. This systematic review focuses on the trend of research works on antibiotic residues, evaluating antibiotics used in livestock production and their excretion in animal products and in environmental matrices such as water and soil. Our database was composed of 165 articles, reporting the concentration of antibiotic residues found in the environment, livestock (cow, sheep, pig, horse, chicken, rabbit, goat), aquatic and terrestrial animal tissues, animal products (milk and eggs), wastewater, and soil. The documents were obtained from Asia, Africa, North America, South America, Europe, and Oceania. A descriptive analysis of antibiotic residues found worldwide was analyzed according to each of the variables used such as antibiotic family, name, concentration (% and mg/kg or ppm), and country and continent where the residue was found. The descriptive analysis was carried out using the “describe” function of psych package and pirate plots were drawn. According to our study, the main antibiotics used worldwide in animal production are sulfonamides, tetracyclines, quinolones, penicillin, and cephalosporins. At present, despite the trends of increased regulations on the use of antibiotics worldwide, antibiotics are still utilized in food animal production, and are present in water and soil, then, there is still the misuse of antibiotics in many countries. We need to become aware that antibiotic contamination is a global problem, and we are challenged to reduce and improve their use.

scholarly journals The Antibiotics Group Aminoglycosides and Macrolides on Beef in Bali

2019 ◽  
Vol 2 (1) ◽  
pp. 39
Author(s):  
Siswanto Siswanto ◽  
I Nyoman Sulabda
Keyword(s):  
Human Health ◽  
Screening Tests ◽  
Antibiotic Residues ◽  
Animal Products ◽  
Good For

Animal products may contain certain ingredients that are not good for human health, such as antibiotic residues. The aim of this research is to know the residue of aminoglycoside and macrolide group antibiotics in Bali beef marketed in Bali-Indonesia. The study used 60 samples of meat from merchant in five different markets: Negara, Tabanan, Denpasar, Singaraja, and Klungkung, where each market was taken 12 samples. Screening tests used to determine antibiotic residues in meat. The results showed only 4 positives from 60 samples containing antibiotics, aminoglycoside 2 sempels (3.33%) and marcrolide 1 sempel (1.67%).

scholarly journals Status of Antibiotic Residues in Poultry Meat of Nepal

2018 ◽  
Vol 35 ◽  
pp. 55-62 ◽  
Author(s):  
M. Prajapati ◽  
E. Ranjit ◽  
R. Shrestha ◽  
S.P. Shrestha ◽  
S.K. Adhikari ◽  
...  
Keyword(s):  
Health Sector ◽  
Poultry Meat ◽  
Enzyme Linked Immunosorbent Assay ◽  
Poultry Production ◽  
Antibiotic Residues ◽  
Animal Products ◽  
Consumer Safety ◽  
Livestock Products ◽  
Antibiotics Residues ◽  
Meat Samples

Antibiotic residues in livestock products are the burning issue in animal production as well as public health sector. Imprudent use of antibiotics in poultry production increases the risk of antibiotic resistance thus increasing risk in both animals and humans. To determine the trend of antibiotic residues presence in poultry meat, a study was conducted from June 2016 to May 2017 in Kathmandu, Kaski, and Chitwan districts of Nepal. A total of 92 breast samples of broilers ( Kathmandu-30, Kaski-40 and Chitwan-22) were collected randomly from different selling outlets of the study areas and tested for residues of commonly used antibiotic viz. Enrofloxacin (EX), Ciprofloxacin (CIP), Streptomycin (STR) and Chloramphenicol (CHL) using the Enzyme Linked Immunosorbent Assay (ELISA) technique. Out of 92 samples, 57 (62%) samples were found positive for antibiotics residue of which 38% samples were positive for STR residue, 15.2% for CIP and 8.7% for EX. However, none of the samples showed positivity for CHL residue. The level of STR was determined to be higher in all districts in comparison to other antibiotics. The meat samples from Kaski were found to contain higher level of STR (56.1%) while highest percentage of CIP (16.1%) was detected in Kathmandu. Also, presence of EX was found highest in Kathmandu compared to other districts. The study concluded that antibiotics residues have been abundantly found in poultry meat which can have serious effect in human health. Hence, to mitigate this, routine antibiotics residues monitoring and surveillance programmes in food animal products should be conducted to ensure the consumer safety.

Concentrations of Antibiotic Residues Vary between Different Edible Muscle Tissues in Poultry

2005 ◽  
Vol 68 (10) ◽  
pp. 2217-2219 ◽  
Author(s):  
IXCHEL REYES-HERRERA ◽  
MARILYN J. SCHNEIDER ◽  
KIMBERLY COLE ◽  
MORGAN B. FARNELL ◽  
PAMELA J. BLORE ◽  
...  
Keyword(s):  
Federal Government ◽  
Thigh Muscle ◽  
Regulatory Agencies ◽  
Target Tissue ◽  
Antibiotic Residues ◽  
Withdrawal Period ◽  
Animal Tissues ◽  
Muscle Tissues ◽  
Specific Muscle ◽  
Antibiotic Residue

Antibiotics are used by veterinarians and producers to treat disease and improve animal production. The federal government, to ensure the safety of the food supply, establishes antibiotic residue tolerances in edible animal tissues and determines the target tissues (e.g., muscle) for residue monitoring. However, when muscle is selected as the target tissue, the federal government does not specify which type of muscle tissue is used for monitoring (e.g., breast versus thigh). If specific muscle tissues incorporate residues at higher concentrations, these tissues should be selected for residue monitoring. To evaluate this possibility in poultry, chickens were divided into four groups and at 33 days of age were dosed with enrofloxacin (Baytril), as per label directions, at either 25 ppm for 3 days, 25 ppm for 7 days, 50 ppm for 3 days, or 50 ppm for 7 days. Breast and thigh muscle tissues were collected from each bird (n = 5 birds per day per group) during the dosing and withdrawal period, and fluoroquinolone concentrations were determined. The results indicate higher overall enrofloxacin concentrations in breast versus thigh muscle for each treatment group (P < 0.05). These data indicate, at least for enrofloxacin, that not all muscle tissues incorporate antibiotics at the same concentrations. These results may be helpful to regulatory agencies as they determine what tissues are to be monitored to ensure that the established residue safety tolerance levels are not exceeded.

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