Hormonal Contraceptive Use Is Associated With Higher Total but Unaltered Free 25-Hydroxyvitamin D Serum Concentrations

AbstractLow serum concentrations of several vitamins have been linked to increased risk of diseases including insulin resistance and type 2 diabetes (T2D). Fish is a good source of several vitamins, and the prevalence of T2D is low in populations with high fish intake. The aim of the present study was to investigate the effects of high fish intake on vitamins in serum from adults in autumn in South-Western Norway at 60° north latitude. In this randomised clinical trial, sixty-three healthy participants with overweight/obesity consumed 750 g/week of either cod (n 22) or salmon (n 22) as five weekly dinners or were instructed to continue their normal eating habits but avoid fish intake (Control group, n 19) for 8 weeks. The estimated vitamin D intake was significantly increased in the Salmon group when compared with the Cod group (P = 6·3 × 10−4) and with the Control group (P = 3·5 × 10−6), with no differences between groups for estimated intake of vitamins A, B1, B2, B3, B6, B9, C and E. Serum 25-hydroxyvitamin D3 concentration was decreased in all groups after 8 weeks; however, the reduction in the Salmon group was significantly smaller compared with the Cod group (P = 0·013) and the Control group (P = 0·0060). Cod and salmon intake did not affect serum concentrations of the other measured vitamins. The findings suggest that 750 g/week of salmon was not sufficient to prevent a decrease in serum 25-hydroxyvitamin D3 in autumn in South-Western Norway in adults with overweight/obesity.

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Serum 25-hydroxyvitamin D Concentrations in Captive and Free-ranging, White-tailed Deer (Odocoileus virginianus)

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831.79.3.180 ◽

2009 ◽

Vol 79 (3) ◽

pp. 180-187 ◽

Cited By ~ 3

Author(s):

W. Ray Waters ◽

Brian J. Nonnecke ◽

Samantha E. J. Gibbs ◽

Michael J. Yabsley ◽

Stephen M. Schmitt ◽

...

Keyword(s):

Metabolic Disease ◽

Odocoileus Virginianus ◽

Seasonal Variations ◽

Additional Research ◽

Serum Concentrations ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D ◽

Free Ranging ◽

Low Serum

Serum concentrations of 25-hydroxyvitamin D [25(OH)D] were determined for free-ranging and captive white-tailed deer (WTD). Effects of gender, season, and age on 25(OH)D concentrations were determined as well as comparisons to concentrations in serum from captive reindeer and elk. Seasonal variations in 25(OH)D concentrations were detected for both captive and free-ranging WTD with greatest concentrations detected in August/September (~ 25 ng/mL) and lowest concentrations in February (~ 5 – 10 ng/mL). Free-ranging WTD < 1 year of age had lower 25(OH)D concentrations (~ 6 ng/mL) than did free-ranging WTD > 1 year of age (~ 12 ng/mL). For captive WTD fawns, 25(OH)D concentrations increased from 1 to 9 days of age (exceeding 100 ng/mL) and then steadily declined to ~ 10 ng/mL by 3 months of age. In general, differences in 25(OH)D concentrations based on gender were not detected. 25(OH)D concentrations in captive WTD did not differ from that of captive reindeer; yet, 25(OH)D concentrations were lower in WTD than in captive elk. Additional research is necessary to determine if low serum 25(OH)D concentrations during the winter or pre-weaning period are associated with increased rates of infectious and metabolic disease.

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No associations between serum concentrations of 25-hydroxyvitamin D and parathyroid hormone and depression among US adults

British Journal Of Nutrition ◽

10.1017/s0007114510002588 ◽

2010 ◽

Vol 104 (11) ◽

pp. 1696-1702 ◽

Cited By ~ 80

Author(s):

Guixiang Zhao ◽

Earl S. Ford ◽

Chaoyang Li ◽

Lina S. Balluz

Keyword(s):

Parathyroid Hormone ◽

Major Depression ◽

Severe Depression ◽

Diagnostic Algorithm ◽

Population Based ◽

Minor Depression ◽

Serum Concentrations ◽

Cross Sectional ◽

Hydroxyvitamin D ◽

25 Hydroxyvitamin D

Although there is evidence that vitamin D deficiency may play a role in depression, studies done on the associations have yielded mixed results. The present study aimed to examine the associations between serum concentrations of 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone (PTH) and the presence of depression among US adults. A cross-sectional, population-based sample (including 3916 participants aged ≥ 20 years) from the 2005–6 National Health and Nutrition Examination Survey was used. Participants' depressive symptoms were assessed using the Patient Health Questionnaire-9 diagnostic algorithm. The associations of 25(OH)D and PTH with depression were explored using multivariate logistic regression models. For all the participants, the age-adjusted prevalence was 5·3 (95 % CI 4·3, 6·5) % for having moderate-to-severe depression, 2·3 (95 % CI 1·7, 3·1) % for having major depression and 3·8 (95 % CI 3·0, 4·6) % for having minor depression. Although the age-adjusted prevalence and the unadjusted OR of having moderate-to-severe depression or major depression decreased linearly with increasing quartiles of 25(OH)D (P < 0·05 for trends), no significant associations remained after adjusting for multiple potential confounders such as demographic variables, lifestyle factors and coexistence of a number of chronic conditions. Neither the age-adjusted prevalence nor the OR (unadjusted or adjusted) of having depression differed significantly by the quartiles of PTH. Thus, in contrast to some of the previous findings, the present results did not show significant associations between serum concentrations of 25(OH)D and PTH and the presence of moderate-to-severe depression, major depression or minor depression among US adults. However, these findings need to be further confirmed in future studies.

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