scholarly journals MON-648 Chronic Unpredictable Environmental Stress May Induce Predisposition to Diabetes Mellitus

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Alok Raghav
Keyword(s):  
Diabetes Mellitus ◽  
Environmental Stress ◽  
Feed Efficiency ◽  
Serum Lipids ◽  
Plasma Insulin ◽  
Fasting Blood Glucose ◽  
Efficiency Ratio ◽  
Metabolizing Enzymes ◽  
Stressed Group ◽  
Feed Efficiency Ratio

Abstract Title: Chronic Unpredictable Environmental Stress may induce predisposition to diabetes mellitus Objective: Chronic unpredictable environmental stress (CUES) may induce predisposition to diabetes mellitus. Material & Methods: This study investigates the role of CUES on impaired homeostasis. Stressed group mice (n=20) were exposed to CUES for 16 weeks. Weekly body weight, feed consumption, feed efficiency ratio, fasting blood glucose were monitored. Plasma HbA1c, plasma cortisol, plasma epinephrine and plasma insulin, serum lipids, antioxidants and carbohydrate metabolizing enzymes activity were assessed along with DNA damage and histopathological examination of liver, kidney, pancreas, spleen and skeletal muscles. Semi-quantitative expression of IL-4, IL-6 and β- actin was also assessed. Results: Fasting blood glucose levels & HbA1c in the stressed were significantly higher compared to control (p<0.001). Serum lipids were found insignificantly higher in stressed mice compared to control. Body weights of the stressed mice and feed efficiency ratio were found significant (p<0.001). Plasma corticosterone, plasma epinephrine, HOMA-IR was found to be significantly higher in the stressed group (p<0.001). Plasma insulin level was found to be significantly lower in the stressed group (p< 0.001). Significant changes were observed in antioxidants level, carbohydrate metabolizing enzymes activity, peripheral tissues and DNA integrity. Expression of IL-4, IL-6 was found significantly higher in the stressed group. Conclusions: CUES initiates pathogenesis of diabetes.

scholarly journals Chronic Unpredictable Environmental Stress Impair Biochemical and Physiological Homeostatsis: Role in Diabetes Mellitus

2018 ◽  
Author(s):  
Alok Raghav ◽  
Jamal Ahmad ◽  
Imrana Naseem
Keyword(s):  
Diabetes Mellitus ◽  
Feed Efficiency ◽  
Serum Lipids ◽  
Plasma Insulin ◽  
Fasting Blood Glucose ◽  
Plasma Epinephrine ◽  
Efficiency Ratio ◽  
Metabolizing Enzymes ◽  
Stressed Group ◽  
Feed Efficiency Ratio

Chronic unpredictable environmental stress (CUES) may induce predisposition to diabetes mellitus. This study investigates the role of CUES on impaired homeostasis. Stressed group mice (n = 20) were exposed to CUES for 16 weeks. Weekly body weight, feed consumption, feed efficiency ratio, fasting blood glucose were monitored. Plasma HbA1c, plasma cortisol, plasma epinephrine and plasma insulin, serum lipids, antioxidants and carbohydrate metabolizing enzymes activity were assessed along with DNA damage and histopathological examination of liver, kidney, pancreas, spleen and skeletal muscles. Fasting blood glucose levels & HbA1c in the stressed were significantly higher compared to control (p < 0.001). Serum lipids were found insignificantly higher in stressed mice compared to control. Body weights of the stressed mice and feed efficiency ratio were found significant (p < 0.001). Plasma corticosterone, plasma epinephrine, HOMA-IR was found to be significantly higher in the stressed group (p < 0.001). Plasma insulin level was found to be significantly lower in the stressed group (p < 0.001). Significant changes were observed in antioxidants level, carbohydrate metabolizing enzymes activity, peripheral tissues and DNA integrity. CUES initiates pathogenesis of diabetes.

scholarly journals Studies on growth performance of Cyprinus carpio var. Communis fed with Bacillus clausii supplemented diets

2021 ◽  
Vol 17 (2) ◽  
pp. 354-358
Author(s):  
Sumira Jan ◽  
Anayitullah Chesti ◽  
Madinat Ul. Nisa ◽  
Misbah Mushtaq ◽  
Shazia Shah
Keyword(s):  
Growth Rate ◽  
Feed Efficiency ◽  
Protein Efficiency Ratio ◽  
Specific Growth ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Control Group ◽  
Feed Conversion ◽  
Efficiency Ratio ◽  
Feed Efficiency Ratio

The present investigation entitled “Studies on growth performance of Cyprinus carpio var. Communis fed with Bacillus clausii supplemented diets” was carried out at Faculty of Fisheries, Ganderbal over a period of 60 days from April 1st to June Ist, 2019. The fingerlings were fed with dry diets containing three concentrations of probiotic viz., (T1: 1%, T2: 1.5%, T3: 2%) and control group (T0: containing no probiotic). The growth parameters including per cent weight gain, Specific growth rate (SGR), feed conversion ratio (FCR), feed efficiency ratio (FER) and protein efficiency ratio (PER) were measured at the end of the experiment. The results showed that the probiotic incorporated diets had significant impact on growth than control group (P<0.05). The highest values of treatment T2 with 2 per cent probiotic showed the highest percent weight gain (74.62%), specific growth rate (0.40), feed efficiency ratio (0.90), protein efficiency ratio (1.82) were observed in treatments with 2% concentration of probiotic where as, feed conversion ratio(1.09) was lower in groups received probiotic through diets than control.

scholarly journals EFFECT OF FORMALIN-TREATED WHEAT IN THE DIET ON THE PERFORMANCE OF GROWING CHICKS

1970 ◽  
Vol 50 (3) ◽  
pp. 601-604 ◽  
Author(s):  
D. B. BRAGG ◽  
H. R. SHARMA ◽  
J. R. INGALLS
Keyword(s):  
Feed Intake ◽  
Feed Efficiency ◽  
Control Diet ◽  
Similar Rate ◽  
Test Period ◽  
White Leghorn ◽  
Efficiency Ratio ◽  
Rate Of Growth ◽  
Feed Efficiency Ratio ◽  
High Level

White Leghorn chicks were fed wheat that was stored under the influence of formalin, and wheat that was recently treated with formalin. Also, samples of each of the formalin-treated wheats were dried and fed to chicks during a four-week test period. Results showed that chicks fed the wheat which was stored under the influence of formalin had a similar rate of growth, feed intake and feed efficiency ratio as those fed the control diet. Dietary wheat recently treated with a high level of formalin resulted in a depression in growth and feed intake as well as poorer feed efficiency ratio. Drying either of the wheat samples after formalin treatment resulted in poor chick performance due to a decrease in feed intake.

scholarly journals Feed and Disease at Olive Flounder (Paralichthys olivaceus) Farms in Korea

Fishes ◽  
2020 ◽  
Vol 5 (3) ◽  
pp. 21
Author(s):  
Joo-Young Jung ◽  
Soohwan Kim ◽  
Kyochan Kim ◽  
Bong-Joo Lee ◽  
Kang-Woong Kim ◽  
...  
Keyword(s):  
Feed Efficiency ◽  
Field Experiments ◽  
Paralichthys Olivaceus ◽  
Management Plan ◽  
Economic Losses ◽  
Selling Price ◽  
Efficiency Ratio ◽  
Feed Efficiency Ratio ◽  
Raw Fish ◽  
Formulated Feed

The objective of this study was to conduct field experiments comparing formulated (extruded pellets (E.P)) and raw-fish (moist pellets (M.P)) feeds at two flounder aquaculture farms for six months to obtain the basic data necessary for improving aquafarmers’ awareness of feed-quality issues and firmly establish and expand the use of formulated feed. According to the results, the M.P group was higher in weight gain, feed efficiency ratio, protein efficiency ratio, and specific growth rate and lower in mortality rate than the E.P group. All cases of mortality were caused by six kinds of disease, four of which (Vibrio sp., Edwardsiella sp., Streptococcus sp., and Scuticociliates) were common to the two groups, whereas Lymphocystis arose only in the M.P group and abdominal inflation only in the E.P group at both farms. As for mortality in the present experiment, the numbers were 1047 at Da-Hae farm and 1167 at Global farm, with more fish dying in the E.P tanks than in the M.P tanks. By multiplying the number of deaths by selling price, the economic losses were $9650 and $10,756, respectively. Therefore, it should be considered an urgent priority to develop flounder-exclusive formulated feed for improved digestion and absorption rate and also to establish a water-quality-improvement management plan.

scholarly journals Effects of Golden Sea Cucumber Extract (Stichopus Hermanii) on Fasting Blood Glucose, Plasma Insulin, and MDA Level of Male Rats (Rattus Norvegicus) Induced with Streptozotocin

2021 ◽  
Vol 55 (2) ◽  
pp. 107
Author(s):  
Dita Sukmaya Prawitasari ◽  
Indri Safitri ◽  
Harianto Notopuro
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Wistar Rats ◽  
Sea Cucumber ◽  
Plasma Insulin ◽  
Fasting Blood Glucose ◽  
Male Rats ◽  
Control Group ◽  
Glucose Plasma

Diabetes mellitus (DM) is one of disease that its incidence increases every year worldwide. The condition of DM can cause various complications caused by oxidative stress. Stichopus hermanii (SH) or golden sea cucumber extract contains antioxidant compounds that have been proven to reduce oxidative stress conditions. The purpose of this study was to investigate the effect of Stichopus hermanii extract on condition of diabetes mellitus by looking at changes in fasting blood glucose, plasma insulin, and malondialdehyde levels in animal models of Wistar rats. This study was a laboratory experimental study using Randomized Control Trial Design with Post-test only control group design. Thirty-five male Wistar rats divided into five groups, i.e normal control group, positive control, negative control and two treatment groups with SH extract dose 8.5 and 17 mg / kgBW for 14 days once daily after induction of Streptozotocin at the Biochemistry Laboratory of the Faculty of Medicine, Airlangga University. Fasting blood glucose level was measured by a glucometer, plasma insulin measured by ELISA and MDA level was measured by a spectrophotometer. Data were analyzed statistically by using One Way ANOVA test and Kruskal Wallis. There were significant results of SH extract can reduce fasting blood glucose (Kruskal Wallis, p=0.030) and MDA (Kruskal Wallis, p=0.042) but not in plasma insulin (ANOVA, p=0.130). The lowest MDA level occurs in the K4 group that given SH extract dose 17 mg/kg BW than another experimental group. As the conclusion, this study showed SH extract can decrease fasting blood glucose and oxidative stress in diabetic-induced rats.

EFFECT OF DIETARY SUPPLEMENTATION OF ZINC ON GROWTH PERFORMANCE AND NUTRIENT UTILIZATION IN KIDS

2016 ◽  
Vol 12 (1) ◽  
Author(s):  
S. Nayak ◽  
L. Thakur ◽  
R.P.S. Baghel ◽  
A.K. Patil ◽  
C.D. Malapure ◽  
...  
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Feed Efficiency ◽  
Crude Protein ◽  
Body Weight Gain ◽  
Basal Diet ◽  
Nutrient Utilization ◽  
Efficiency Ratio ◽  
Feed Efficiency Ratio ◽  
Average Body

Present study was undertaken to evaluate the effect of zinc supplementation on growth performance and nutrient utilization in kids. Twenty four goat kids (4-6 month age) were randomly divided into 4 groups (T1, T2, T3 and T4) having 6 kids each. Kids in the group T1 were fed basal diet which contained 29.02 mg Zn/kg DM from ingredients of ration without any additional Zn supplementation. Kids in the T2, T3 and T4 groups were fed the same basal diet with additive 20, 50 and 100 ppm Zn (as ZnSO4) in their diets, respectively. The study was conducted for 90 days. Digestion trial of 7 days was conducted towards the end of experiment to assess the digestibility of the nutrients. Results indicated significantly higher average body weight gain, crude protein (CP) digestibility and better feed efficiency in kids fed diet supplemented with 50.0 mg Zn/kg DM. From the results it was concluded that the Zn supplementation @ 50.0 mg/kg DM in basal diet significantly improved body weight (BW) gain, CP digestibility and feed efficiency ratio (FER) of kids.

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