Prolonged Low-moderate Intensity Exercise On Physiological Markers Of Metabolic And Oxidative Stress

2018 ◽  
Vol 50 (5S) ◽  
pp. 248-249
Author(s):  
Dominique Gagnon ◽  
Sandra Dorman ◽  
Stephen Ritchie ◽  
Shivaprakash Jagalur Mutt ◽  
Ville Stenbäck ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Physiological Markers ◽  
And Oxidative Stress

scholarly journals Individuals with controlled hypertension show endothelial integrity following a bout of moderate-intensity exercise: randomized clinical trial

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Gustavo Waclawovsky ◽  
Liliana F. C. Boll ◽  
Bruna Eibel ◽  
Ana Paula Alegretti ◽  
Fabiane Spagnol ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Clinical Trial ◽  
Progenitor Cells ◽  
Vascular Function ◽  
Exercise Bout ◽  
Moderate Intensity ◽  
Acute Effects ◽  
Moderate Intensity Exercise ◽  
Post Intervention ◽  
And Oxidative Stress

AbstractTo examine the acute effects of aerobic exercise (AE), resistance exercise (RE) or combined exercise (CE) on flow-mediated dilation (FMD), progenitor cells (PCs), endothelial progenitor cells (EPCs), oxidative stress markers and endothelial-cell derived microvesicles (EMVs) in patients with hypertension. This is a randomized, parallel-group clinical trial involving an intervention of one session of three different modalities of exercise. Thirty-three males (43 ± 2y) were randomly divided into three groups: a session of AE (n = 11, 40 min, cycle ergometer, 60% HRR); a session of RE (n = 11, 40 min, 4 × 12 lower limb repetitions, 60% 1-RM); or a session of CE (n = 11, 20-min RE + 20-min AE). FMD was assessed 10 min before and 10, 40 and 70 min post-intervention. Blood samples were collected at the same time points (except 40 min). FMD were similar in all groups and from baseline (within each group) after a single exercise bout (AE, RE or CE). At 70 min, RE group showed higher levels of PCs compared to the AE (81%) and CE group (60%). PC levels were reduced from baseline in all groups (AE: 32%, p = 0.037; RE: 15%, p = 0.003; CE: 17%, p = 0.048). The levels of EPCs, EMVs and oxidative stress were unchanged. There were no acute effects of moderate-intensity exercise on FMD, EPCs, EMVs and oxidative stress, but PCs decreased regardless of the exercise modality. Individuals with controlled hypertension do not seem to have impaired vascular function in response to a single exercise bout.

Moderate Intensity Exercise Decreases Oxidative Stress in Metallothionein Deficient Mice

2010 ◽  
Vol 42 ◽  
pp. 306-307
Author(s):  
Scott R. Collier ◽  
Keith DeRuisseau ◽  
Vincent Frechette ◽  
Hong Ji ◽  
W Zheng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Deficient Mice

scholarly journals Effect of 2-weeks Coenzyme Q10 Supplementation on Malondialdehyde and Catalase Serum Levels Following Moderate and Severe Acute Resistance Training in Inactive Female Students

2019 ◽  
Vol 25 (4) ◽  
pp. 256-269
Author(s):  
Yeganeh Feizi ◽  
◽  
Mohammad Esmaeil Afzalpur ◽  
Seyed-Hosein Abtahi-Eivary ◽  
◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Resistance Training ◽  
Coenzyme Q10 ◽  
Serum Levels ◽  
Female Students ◽  
Moderate Intensity ◽  
Control Group ◽  
Short Term ◽  
Coenzyme Q10 Supplementation ◽  
And Oxidative Stress

Aims Physical activity is usually accompanied by free radicals’ production and oxidative stress. Moreover, to prevent adverse effects, coaches and athletes have to use proper supplementation. Therefore, the present study aimed to investigate the effect of short-term coenzyme Q10 supplementation on malondialdehyde and serum catalase enzyme activity following moderate and severe acute resistance training in inactive female students. Methods & Materials In total, 27 female students were randomly divided into three groups; the groups were homogeneous and equal (two groups of resistance training and one control group). The experimental groups were subjected to moderate-intensity acute (70% 1RM) acute and severe acute activity (85% 1RM) and supplemented with coenzyme Q10 (30 mg /d). CAT and MDA were measured in ELISA using a human kit. Findings Moderate and severe acute resistance activities did not alter MDA and catalytic activity (P>0.05); however, after 2 weeks of coenzyme Q10 supplementation, those resulted in a significant decrease in MDA (0.006 and 0.01, respectively) and CAT (0.04 and 0.007, respectively). There were no significant differences between the effects of two exercises (P>0.05). Conclusion Short-term (two weeks) supplementation of coenzyme Q10 and severe acute resistance activity could reduce two important oxidative stress indexes (MDA and CAT).

scholarly journals Cigarette Smoking does not Induce Plasma or Pulmonary Oxidative Stress after Moderate-intensity Exercise

2014 ◽  
Vol 26 (3) ◽  
pp. 413-415 ◽  
Author(s):  
Shunsuke Taito ◽  
Sayaka Domen ◽  
Kiyokazu Sekikawa ◽  
Norimichi Kamikawa ◽  
Keisuke Oura ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cigarette Smoking ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Induce Plasma

Abstract 170: Role of Central GSK-3ß in Mediating Exercise-induced Improvement in Inflammatory Cytokines and Reduction in Blood Pressure in Hypertensive Rats

Hypertension ◽  
2013 ◽  
Vol 62 (suppl_1) ◽  
Author(s):  
Deepmala Agarwal ◽  
Rahul B Dange ◽  
Joseph Francis
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Cytokines ◽  
Radio Telemetry ◽  
Moderate Intensity ◽  
Sprague Dawley ◽  
Hypertensive Rats ◽  
Beneficial Effects ◽  
Gsk 3Β ◽  
Exercise Induced ◽  
And Oxidative Stress

Although exercise has been recommended for the treatment of hypertension (HTN), the precise mechanisms of effects of exercise training (ExT) in HTN remain largely unexplored. Based on our recent unpublished results, here we tested the hypothesis that central increase in GSK-3β activity would cause reversal of effects of ExT in HTN. To increase GSK-3β activity in the brain, we chronically injected Triciribine (TCN) by intracerebroventricular (ICV) route. 90 Sprague-Dawley rats were randomized into six groups (n=15/group): 1) Sal+Ex+Veh; 2) Sal+Ex+TCN; 3) AngII+Sed+Veh; 4) AngII+Sed+TCN; 5) AngII+Ex+Veh; 6) AngII+Ex+TCN (Sal, saline; Ex, exercise; Veh, vehicle; Sed, sedentary). Rats were given AngII (hypertensive) or Veh (Normotensive) via osmotic minipumps. Groups 1, 2, 5, and 6 received moderate-intensity ExT for 42 days; groups 3 and 4 were sedentary. MAP was measured by radio-telemetry and cardiac function by echocardiography. The PVN tissues were examined for TNF, IL-1β, IL-10, and oxidative stress markers (iNOS, NOX2) levels. ExT delayed the progression of HTN, and improved cardiac hypertrophy and function in hypertensive rats. Chronic ICV infusion of TCN prevented these beneficial changes (Table). TCN prevented exercise-induced improvement in balance between pro- and anti-inflamamtory cytokines as well as exercise-induced reduction in oxidative stress within the PVN of hypertensive rats. These findings provide direct evidence that the beneficial effects of regular moderate-intensity ExT in HTN are mediated, at least in part, by reduced activation of central GSK-3β and potentially via improvement in inflammatory cytokines and oxidative stress within the PVN.

scholarly journals Effects of Concurrent Training on Oxidative Stress and Insulin Resistance in Obese Individuals

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Niara da Silva Medeiros ◽  
Fabiana Guichard de Abreu ◽  
Alana Schraiber Colato ◽  
Leandro Silva de Lemos ◽  
Thiago Rozales Ramis ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Insulin Resistance ◽  
Body Weight ◽  
Oxidative Damage ◽  
Body Fat ◽  
Moderate Intensity ◽  
Concurrent Training ◽  
Tbars Level ◽  
Anthropometric Parameters ◽  
And Oxidative Stress

Obesity is associated with insulin resistance (IR) and increased oxidative stress. Thus, the present study aimed to evaluate anthropometric parameters, IR, and oxidative stress in obese individuals subjected to two types of concurrent training at the same intensity but differing in frequency. Accordingly, 25 individuals were divided into two groups: concurrent training 1 (CT1) (5 d/wk) and concurrent training 2 (CT2) (3 d/wk), both with moderate intensity. Anthropometric parameters, IR, and oxidative stress were analyzed before and after 26 sessions of training. Both groups had reduced body weight and body mass index (P<0.05), but only CT1 showed lower body fat percentage and increased basal metabolic rate (P<0.05). Moreover, CT1 had increased HOMA-IR and decreased protein damage (carbonyl level), and CT2 had decreased HOMA-IR and increased lipid peroxidation (TBARS level) (P<0.05). On the other hand, both training protocols reduced the GPx activity. It can be concluded that both types of concurrent training could be an alternative for lowering body weight and BMI. Also, it was observed that concurrent training, depending on the frequency, can contribute to reducing body fat, oxidative damage (protein oxidation), and IR but can induce oxidative damage to lipids. More studies are needed to elucidate the mechanisms involved.

scholarly journals Effect of Exercise on Kidney Function, Oxidative Stress, and Inflammation in Type 2 Diabetic KK-AyMice

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Yuji Ishikawa ◽  
Tomohito Gohda ◽  
Mitsuo Tanimoto ◽  
Keisuke Omote ◽  
Masako Furukawa ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Oxidative Damage ◽  
Body Weight Loss ◽  
Moderate Intensity ◽  
Moderate Intensity Exercise ◽  
Beneficial Effects ◽  
Low Intensity ◽  
Exercise Regimen ◽  
Type 2 Diabetic

Exercise is recommended for the management of type 2 diabetes, but its effects on diabetic nephropathy (DN) are still unknown. We hypothesized that appropriate exercise improves early DN via attenuation of inflammation and oxidative damage. Type 2 diabetic KK-Aymice, a spontaneous DN model, underwent two different kinds of exercise (i.e., moderate and low intensity). Sedentary mice or those undergoing an exercise regimen causing no significant body weight loss were used. We examined the urinary excretion of albumin, number of podocytes and macrophages, renal expressions of HIF-1αand MCP-1, and biomarkers of oxidative stress such as urinary 8-OHdG and serum SOD. Exercise reduced urinary levels of albumin and also maintained the number of podocytes in the exercised KK-Aymice independently of improvements of overweight and hyperglycemia, although moderate-intensity exercise increased expression of HIF-1α. Sedentary KK-Aymice showed increased expression of MCP-1 and infiltration of macrophage, increased urinary 8-OhdG, and decreased serum SOD levels compared with exercised KK-Aymice. On the whole, low-intensity exercise attenuates progression of early DN without affecting marked renal ischemia. Reduction rates of urinary albumin and maintained podocyte numbers, with parallel improvements in oxidative damage and inflammation, are related to beneficial effects of exercise in diabetic kidney disease.

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