scholarly journals The Legacy of Colonial Medicine in Central Africa

2021 ◽  
Vol 111 (4) ◽  
pp. 1284-1314
Author(s):  
Sara Lowes ◽  
Eduardo Montero
Keyword(s):  
Side Effects ◽  
World Bank ◽  
Blood Test ◽  
Health Sector ◽  
Central Africa ◽  
Colonial Medicine ◽  
African Countries ◽  
Vaccination Rates ◽  
Health Initiatives ◽  
French Colonial

Between 1921 and 1956, French colonial governments organized medical campaigns to treat and prevent sleeping sickness. Villagers were forcibly examined and injected with medications with severe, sometimes fatal, side effects. We digitized 30 years of archival records to document the locations of campaign visits at a granular geographic level for five central African countries. We find that greater campaign exposure reduces vaccination rates and trust in medicine, as measured by willingness to consent to a blood test. We examine relevance for present-day health initiatives; World Bank projects in the health sector are less successful in areas with greater exposure. (JEL F54, I12, I15, I18, N37, N47, Z13)

scholarly journals Hydroxychloroquine and Azithromycin Treatment of Hospitalized Patients Infected with SARS-CoV-2 in Senegal from March to October 2020

2021 ◽  
Vol 10 (13) ◽  
pp. 2954
Author(s):  
Fabien Taieb ◽  
Khardiata Diallo Mbaye ◽  
Billo Tall ◽  
Ndèye Aïssatou Lakhe ◽  
Cheikh Talla ◽  
...  
Keyword(s):  
Side Effects ◽  
Clinical Characteristics ◽  
Clinical Status ◽  
Group Versus ◽  
Patient Discharge ◽  
Lower Proportion ◽  
Hospitalized Patients ◽  
African Countries ◽  
Factors Associated ◽  
High Clinical Risk

As of today, little data is available on COVID-19 in African countries, where the case management relied mainly on a treatment by association between hydroxychloroquine (HCQ) and azithromycin (AZM). This study aimed to understand the main clinical outcomes of COVID-19 hospitalized patients in Senegal from March to October 20202. We described the clinical characteristics of patients and analysed clinical status (alive and discharged versus hospitalized or died) at 15 days after Isolation and Treatment Centres (ITC) admission among adult patients who received HCQ plus AZM and those who did not receive this combination. A total of 926 patients were included in this analysis. Six hundred seventy-four (674) (72.8%) patients received a combination of HCQ and AZM. Results showed that the proportion of patient discharge at D15 was significantly higher for patients receiving HCQ plus AZM (OR: 1.63, IC 95% (1.09–2.43)). Factors associated with a lower proportion of patients discharged alive were: age ≥ 60 years (OR: 0.55, IC 95% (0.36–0.83)), having of at least one pre-existing disorder (OR: 0.61, IC 95% (0.42–0.90)), and a high clinical risk at admission following NEWS score (OR: 0.49, IC 95% (0.28–0.83)). Few side effects were reported including 2 cases of cardiac rhythmic disorders in the HCQ and AZM group versus 13 in without HCQ + AZM. An improvement of clinical status at 15 days was found for patients exposed to HCQ plus AZM combination.

scholarly journals Evaluating the impact of public health initiatives on trends in fecal occult blood test participation in Ontario

BMC Cancer ◽  
2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Gladys N Honein-AbouHaidar ◽  
Linda Rabeneck ◽  
Lawrence F Paszat ◽  
Rinku Sutradhar ◽  
Jill Tinmouth ◽  
...  
Keyword(s):  
Public Health ◽  
Blood Test ◽  
Fecal Occult Blood Test ◽  
Occult Blood ◽  
Fecal Occult Blood ◽  
Occult Blood Test ◽  
Fecal Occult ◽  
Health Initiatives ◽  
The Impact ◽  
Public Health Initiatives

Political Stability in Africa: A Cross-National Analysis

2021 ◽  
pp. 002190962110544
Author(s):  
Gizachew Tiruneh
Keyword(s):  
Political Stability ◽  
African Countries ◽  
Cross Sectional ◽  
Founding Fathers ◽  
Colonial Legacy ◽  
Development Regime ◽  
French Colonial ◽  
British Colonial ◽  
National Analysis ◽  
The Impact

The main objective of this paper is to test the influence of Africa’s founding fathers and the impact of British colonial legacy on the political stability of Africa. We relied on a sample of 50 African countries and employed cross-sectional research designs, which covered two separate periods (1960–1989 and 1990–2018). Using logistic regression and OLS estimators and controlling for French colonial legacy, economic development, regime type, ethnic heterogeneity, and ethnic polarization, we found that the founding fathers were conducive to Africa’s political stability between 1960 and 2018. We also found that British colonial legacy had some impact on former British colonies’ stability between 1960 and 2018. In addition, GDP per capita had a significant impact on Africa’s political stability over the two periods.

Infrastructure Provisioning and Health Service Utilization in Africa

2017 ◽  
Vol 3 (1) ◽  
pp. 47-69 ◽  
Author(s):  
Amm Quamruzzaman
Keyword(s):  
Health Service ◽  
Service Utilization ◽  
Health Service Utilization ◽  
Access To Health Care ◽  
National Level ◽  
Health Sector ◽  
Local Health ◽  
African Countries ◽  
Individual Level ◽  
Different Levels

Although the positive developmental effects of infrastructure provisioning are well documented, research on the potential role of governance in the improvement of infrastructure performance and individual-level service utilization is lacking. I explore the effect of infrastructure provisioning on individual-level health service utilization, paying close attention to whether governance at different levels shapes people's access to health care. The different geographical levels of infrastructure provisioning, governance, and health service utilization require a multilevel analysis, which I perform using Afrobarometer Round 5 survey data on 34 African countries in a three-stage mixed-effects modeling. Results show that the presence of health infrastructure is crucial for enhancing people's health service utilization. However, people encounter certain problems when receiving services at their local health clinics or hospitals, and these problems are directly linked with governance in the health sector as well as overall governance at the country level. Improvements in people's health service utilization therefore require both better infrastructure provisioning and better governance at different levels, as the former does not guarantee the latter. Development scholars need to widen their focus beyond national-level governance and help policy makers identify at which level state interventions are most needed for removing barriers to development.

scholarly journals Prevalence of Mutations in the pfcoronin Gene and Association with Ex Vivo Susceptibility to Common Quinoline Drugs against Plasmodium falciparum

Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1273
Author(s):  
Océane Delandre ◽  
Mathieu Gendrot ◽  
Isabelle Fonta ◽  
Joel Mosnier ◽  
Nicolas Benoit ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Sanger Sequencing ◽  
Ex Vivo ◽  
Central Africa ◽  
Artemisinin Resistance ◽  
Current Data ◽  
Artemisinin Derivative ◽  
African Countries ◽  
Low Prevalence

Background: Artemisinin-based combination therapy (ACT) was recommended to treat uncomplicated falciparum malaria. Unlike the situation in Asia where resistance to ACT has been reported, artemisinin resistance has not yet emerged in Africa. However, some rare failures with ACT or patients continuing to be parasitaemic on day 3 after ACT treatment have been reported in Africa or in travellers returning from Africa. Three mutations (G50E, R100K, and E107V) in the pfcoronin gene could be responsible for artemisinin resistance in Africa. Methods: The aims of this study were first to determine the prevalence of mutations in the pfcoronin gene in African P. falciparum isolates by Sanger sequencing, by targeting the 874 samples collected from patients hospitalised in France after returning from endemic areas in Africa between 2018 and 2019, and secondly to evaluate their association with in vitro reduced susceptibility to standard quinoline antimalarial drugs, including chloroquine, quinine, mefloquine, desethylamodiaquine, lumefantrine, piperaquine, and pyronaridine. Results: The three mutations in the pfcoronin gene (50E, 100K, and 107V) were not detected in the 874 P. falciparum isolates. Current data show that another polymorphism (P76S) is present in many countries of West Africa (mean prevalence of 20.7%) and Central Africa (11.9%) and, rarely, in East Africa (4.2%). This mutation does not appear to be predictive of in vitro reduced susceptibility to quinolines, including artemisinin derivative partners in ACT such as amodiaquine, lumefantrine, piperaquine, pyronaridine, and mefloquine. Another mutation (V62M) was identified at low prevalence (overall prevalence of 1%). Conclusions: The 76S mutation is present in many African countries with a prevalence above 10%. It is reassuring that this mutation does not confer in vitro resistance to ACT partners.

scholarly journals First Report of East African Cassava Mosaic Begomovirus in Nigeria

Plant Disease ◽  
1999 ◽  
Vol 83 (4) ◽  
pp. 398-398 ◽  
Author(s):  
F. O. Ogbe ◽  
G. I. Atiri ◽  
D. Robinson ◽  
S. Winter ◽  
A. G. O. Dixon ◽  
...  
Keyword(s):  
Central Africa ◽  
Mosaic Disease ◽  
Sub Saharan Africa ◽  
Cassava Mosaic Disease ◽  
Enzyme Linked Immunosorbent Assay ◽  
East African ◽  
African Countries ◽  
Manihot Esculenta Crantz ◽  
Cross River State ◽  
Sub Saharan

Cassava (Manihot esculenta Crantz) is an important food crop in sub-Saharan Africa. One of the major production constraints is cassava mosaic disease caused by African cassava mosaic (ACMV) and East African cassava mosaic (EACMV) begomoviruses. ACMV is widespread in its distribution, occurring throughout West and Central Africa and in some eastern and southern African countries. In contrast, EACMV has been reported to occur mainly in more easterly areas, particularly in coastal Kenya and Tanzania, Malawi, and Madagascar. In 1997, a survey was conducted in Nigeria to determine the distribution of ACMV and its strains. Samples from 225 cassava plants showing mosaic symptoms were tested with ACMV monoclonal antibodies (MAbs) in triple antibody sandwich enzyme-linked immunosorbent assay (1). Three samples reacted strongly with MAbs that could detect both ACMV and EACMV. One of them did not react with ACMV-specific MAbs while the other two reacted weakly with such MAbs. With polymerase chain reaction (2), the presence of EACMV and a mixture of EACMV and ACMV in the respective samples was confirmed. These samples were collected from two villages: Ogbena in Kwara State and Akamkpa in Cross River State. Co-infection of some cassava varieties with ACMV and EACMV leads to severe symptoms. More importantly, a strain of mosaic geminivirus known as Uganda variant arose from recombination between the two viruses (2). This report provides evidence for the presence of EACMV in West Africa. References: (1) J. E. Thomas et al. J. Gen. Virol. 67:2739, 1986. (2) X. Zhou et al. J. Gen. Virol. 78:2101, 1997.

scholarly journals Repenser Le Rôle Des Institutions De Conservation De La Nature À L’ère De La Globalisation En Afrique: À Propos Du Parc National De La Salonga (RDC)

2017 ◽  
Vol 13 (11) ◽  
pp. 92
Author(s):  
Mampeta Wabasa Salomon
Keyword(s):  
Protected Areas ◽  
National Park ◽  
Local Community ◽  
Democratic Republic ◽  
Central Africa ◽  
The Other ◽  
African Countries ◽  
Republic Of The Congo ◽  
Contemporary Management

In the Democratic Republic of the Congo (DRC), the protectionist conservatism influenced by colonialism, which exploited African countries for the prosperity of the colonizing countries, still has a high visibility in the Salonga National Park (PNS). If, in theory, the Central Africans seem to free themselves from the colonial powers on their land, in practice they are still there. The hostility of settlers who have become neo-colonists to the development of Central Africa remains intact, he adds (Ndinga, 2003). This reflects a "logic from above" that has disregarded local values. Yet, in the era of sustainable development and globalization, African protected areas appear to be essential tools for States to reposition themselves in a complex set of actors with the aim of capturing and using the new environmental rent (Giraut, Guyot, & Houssay-Holzschuch, 2003). This is a "bottom-up logic", placing people at the heart of all activities and aiming to reorganize their long-term relationships with the environment. From these two logics, a third "logic from the other side" emerges, reflecting a collective awareness of the fragility of the planet. The restoration of the rights of Africans in the various national frameworks constitutes a major challenge for the contemporary management of African protected areas. Because the protected areas inherited from the different colonial systems must accompany the change in management methods and the redefinition of their functions in order to better serve the local community in the long-term.

scholarly journals The impact of visa status and Medicare eligibility on people diagnosed with HIV in Western Australia: a qualitative report

Sexual Health ◽  
2012 ◽  
Vol 9 (5) ◽  
pp. 407 ◽  
Author(s):  
Susan Herrmann ◽  
Joan Wardrop ◽  
Mina John ◽  
Silvana Gaudieri ◽  
Michaela Lucas ◽  
...  
Keyword(s):  
Side Effects ◽  
Generic Drugs ◽  
Health Sector ◽  
Antiretroviral Drugs ◽  
Access To Treatment ◽  
Hiv Serostatus ◽  
Permanent Residency ◽  
The Impact ◽  
Permanent Residents ◽  
Rate Of Response

Background: In Australia, temporary visa holders are ineligible for Medicare and subsidised antiretroviral drugs. Additionally, HIV testing is not mandatory for visas unless applicants seek work in the health sector. We sought to understand the impact of HIV and issues of access and adherence to antiretroviral therapy (ART) in people holding temporary visas and permanent residents. Methods: Data were gathered from interviews with 22 participants. Information concerning medication adherence, side effects, CD4 T-cell count, viral load and rate of response to generic drugs were collected. Results: The mean age was 33.4 years (±s.d. = 6.0), 21 out of 22 were from HIV-prevalent areas in East Africa and Asia, 14 out of 22 were on temporary visas, 12 were ineligible for Medicare, 14 out of 22 were diagnosed during health screening, 19 out of 22 risk exposures were in country of origin, 8 out of 17 were taking generic ART at an average cost of $180 per month, adherence was excellent and self-reported side-effects were relatively infrequent. Participants applying for visa continuations and permanent residency were fearful, believing their HIV serostatus would prejudice their applications. Patients cited belief in ART efficacy, were motivated to maintain therapy and were anxious about lack of access to treatment in their countries of origin. Conclusion: Adherence to antiretroviral drugs in Medicare-ineligible HIV-infected individuals is excellent despite limited access to treatment. The threat of visa non-renewal and the likely failure of applications for permanent residency result in considerable anxiety and confidentiality concerns.

scholarly journals The acceptance of covid-19 vaccines in Sub-Saharan Africa: Evidence from 6 national phone surveys

2021 ◽  
Author(s):  
Shelton Kanyanda ◽  
Yannick Markhof ◽  
Philip Wollburg ◽  
Alberto Zezza
Keyword(s):  
Side Effects ◽  
Low Income ◽  
Urban Areas ◽  
Vaccine Coverage ◽  
Sub Saharan Africa ◽  
Low Income Countries ◽  
Vaccine Hesitancy ◽  
African Countries ◽  
Representative Sampling ◽  
Sub Saharan

Introduction Recent debates surrounding the lagging covid-19 vaccination campaigns in low-income countries center around vaccine supply and financing. Yet, relatively little is known about attitudes towards covid-19 vaccines in these countries and in Africa in particular. In this paper, we provide cross-country comparable estimates of the willingness to accept a covid-19 vaccine in six Sub-Saharan African countries. Methods We use data from six national high-frequency phone surveys from countries representing 38% of the Sub-Saharan African population (Burkina Faso, Ethiopia, Malawi, Mali, Nigeria, and Uganda). Samples are drawn from large, nationally representative sampling frames providing a rich set of demographic and socio-economic characteristics by which we disaggregate our analysis. Using a set of re-calibrated survey weights, our analysis adjusts for the selection biases common in remote surveys. Results Acceptance rates in the six Sub-Saharan African countries studied are generally high, with at least four in five people willing to be vaccinated in all but one country. Vaccine acceptance ranges from nearly universal in Ethiopia (97.9%, 97.2% to 98.6%) to below what would likely be required for herd immunity in Mali (64.5%, 61.3% to 67.8%). We find little evidence for systematic differences in vaccine hesitancy by sex or age but some clusters of hesitancy in urban areas, among the better educated, and in richer households. Safety concerns about the vaccine in general and its side effects emerge as the primary reservations toward a covid-19 vaccine across countries. Conclusions Our findings suggest that limited supply, not inadequate demand, likely presents the key bottleneck to reaching high covid-19 vaccine coverage in Sub-Saharan Africa. To turn intent into effective demand, targeted communication campaigns bolstering confidence in the safety of approved vaccines and reducing concerns about side effects will be crucial to safeguard the swift progression of vaccine rollout in one of the world's poorest regions.

scholarly journals From Prussia to China: Japanese Colonial Medicine and Gotō Shinpei’s Combination of Medical Police and Local Self-Administration

2011 ◽  
Vol 55 (3) ◽  
pp. 343-347 ◽  
Author(s):  
Christos Lynteris
Keyword(s):  
Public Health ◽  
Colonial Medicine ◽  
Republican China ◽  
Self Administration ◽  
Japanese Colonialism ◽  
Health Initiatives ◽  
Historical Investigation ◽  
Key Issues ◽  
Japanese Colonial ◽  
Public Health Initiatives

Recent historical investigation into the rise of ‘biopolitical modernity’ in China has shed some surprising light. While it was long thought that British public health initiatives entered China via Hong Kong, the recent work of Ruth Rogaski, Philippe Chemouilli and others has established that it was actually early Japanese colonialism that played the crucial role. It was the Meiji Empire's hygiene reform projects in Taiwan and Manchuria that provided the model for Republican China. Curiously overlooked by medical historians has been one of the major early works of Japanese public health that directly inspired and guided this colonial medical enterprise. This was that of the Japanese health reformer and colonial officer, Gotō Shinpei (1857–1929), and it was undertaken in Munich as a doctoral thesis under the supervision of Max von Pettenkofer. In this article, I focus on the way in which Shinpei dealt in his thesis with the relations between centralisation and local self-administration as one of the key issues facing hygienic modernisation and colonial biopolitical control.

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