scholarly journals Maternal and Perinatal outcome after Ramadan Fasting

2020 ◽  
Vol 36 (5) ◽  
Author(s):  
Rashida Parveen ◽  
Mehnaz Khakwani ◽  
Munazza Latif ◽  
Ayesha Uzaima Tareen

Objective: To determine maternal and perinatal outcome after Ramadan fasting during pregnancy Methods: This cross sectional study was conducted at The Department of Obstetrics and Gynaecology, Nishtar Hospital, Multan from May to October 2019. A total of 226 women attending labour room, aged 18–35 years, having gestational amenorrhoea 15 – 40 weeks of gestation were included. Women who fasted for more than 15 days were compared with those who did not fast or fasted for less than 15 days in the month of Ramadan. Demographical profile along with maternal and perinatal outcomes were compared between the study groups considering p value less than 0.05 as significant. Results: Out of 226 women, 58 (25.7%) fulfilled the criteria to be included in the fasting group while remaining 168 (74.3%) were slotted in the non-fasting group. There was no difference (p value > 0.05) in between the both group with respect to demographical characteristics except significantly less women were employed in the fasting group (p value=0.0246). No statistical difference was found in terms of maternal or perinatal outcomes between both the study groups. Conclusion: Fasting women were not found to have poor maternal and fetal outcomes when compared to non-fasting women. doi: https://doi.org/10.12669/pjms.36.5.2612 How to cite this:Parveen R, Khakwani M, Latif M, Tareen AU. Maternal and Perinatal outcome after Ramadan Fasting. Pak J Med Sci. 2020;36(5):---------. doi: https://doi.org/10.12669/pjms.36.5.2612 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

2021 ◽  
Vol 38 (ICON-2022) ◽  
Author(s):  
Faiza Ahmed ◽  
Lubna Abbasi ◽  
Fivzia Herekar ◽  
Ahsun Jiwani ◽  
Muhammad Junaid Patel

Objectives: To assess knowledge and perception among Pakistani physicians towards sepsis. Methods: This cross-sectional study was conducted in Indus Hospital and Health Networks from September 2020 to March 2021. The International Sepsis Survey questionnaire was adapted, and its link was sent to trainee physicians as well as specialists, and consultants practicing in various hospitals via social media. Knowledge and perception were scored and 50% was considered the cut-off score for adequacy. Data was analyzed using SPSS version 26. Results: Analysis was done on 222 respondents who completed the survey. 37.9% of the participants had adequate knowledge. Knowledge regarding sepsis was significantly associated with specialty, ICU/CCU/HDU, and work experience (P-value <0.0001). More recent trainee physicians and those with more experience in critical care areas demonstrated better knowledge. Over 2/3rd of the respondents strongly agreed that sepsis remains one of the unmet needs in critical care today. Conclusion: A common belief exists that sepsis remains a challenge to treat among doctors. Moreover, there is consensus that it is the most frequently miss diagnosed condition in critical care and a dire need exists for its early diagnosis. Additionally, prompt management of presumed sepsis is imperative to improve outcomes. doi: https://doi.org/10.12669/pjms.38.ICON-2022.5775 How to cite this:Ahmed F, Abbasi L, Herekar F, Jiwani A, Patel MJ. Knowledge and perception of Sepsis among Doctors in Karachi Pakistan. Pak J Med Sci. 2022;38(2):380-386. doi: https://doi.org/10.12669/pjms.38.ICON-2022.5775 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Author(s):  
Ivan Buntara ◽  
Yohanes Firmansyah ◽  
Hendsun Hendsun ◽  
Ernawati Su

Gastroesophageal Reflux Disease (GERD) is a form of gastrointestinal motility disorder, where stomach contents reenter the esophagus and oral cavity, causing symptoms and complications. GERD is a condition that is quite often experienced, where the prevalence estimated at 8 - 33% worldwide. One of the suspected cause of  GERD is Ramadan fasting, which has been routinely carried out by Muslim groups. This study aims to prove whether Ramadan fasting triggers GERD. A cross-sectional study (survey) conducted online via Google form on the last three days of the fasting month (21 May 2020 - 23 May 2020). The variables in this study were respondents who fasted Ramadan and those who did not fast, also the total value of the GERD-Q questionnaire along with the final conclusions. Statistical analysis using Chi square with Yates Correction and Independent T-test with Mann Whitney Alternative Test. 311 respondents met the inclusion criteria. The results of Mann Whitney statistical test found that there was no difference in the mean value of the total GERD-Q questionnaire between the fasting and non-fasting groups (p-value: 0.313). Pearson Chi Square with Yates Correction results found no significant relationship between fasting and incidence of GERD (p-value: 0.552), although clinically there was a possibility of fasting had a risk of 1,228 (95% CI: 0.772 -2,088) times to trigger GERD incident.as Conclusion, Ramadan fasting has not been shown to improve GERD symptoms. Further research needs to be done through longitudinal studies. Keywords: GERD; digestion; Ramadan fastingABSTRAKGastroesophageal Reflux Disease (GERD) merupakan suatu bentuk gangguan motilitas saluran cerna, dimana isi lambung masuk kembali ke dalam esofagus dan rongga mulut, sehingga menyebabkan gejala dan komplikasi. GERD merupakan kondisi yang cukup sering dialami, dimana prevalensinya diperkirakan mencapai 8 – 33% di seluruh dunia. Salah satu faktor yang diperkirakan sebagai penyebab GERD adalah puasa Ramadhan yang selama ini rutin dijalankan oleh kelompok Muslim. Penelitian ini bertujuan untuk membuktikan apakah puasa Ramadhan mencetuskan kejadian GERD. Penelitian potong lintang (survei) yang dilaksanakan secara online melalui google form pada tiga hari terakhir bulan puasa Ramadhan 2020 (21 Mei 2020 – 23 Mei 2020). Variabel dalam penelitian ini adalah responden yang berpuasa Ramadhan maupun yang tidak berpuasa Ramadhan dan nilai total kuesioner GERD-Q beserta kesimpulan akhir dari kuesioner GERD-Q. Analisis statistik menggunakan uji statistik Chi square with Yates Correction dan Independent T-test dengan Uji Alternatif Mann Whitney. 311 responden memenuhi kriteria inklusi. Hasil uji statistik Mann Whitney tidak terdapat perbedaan rerata nilai total kuesioner GERD-Q antara kelompok yang berpuasa dan tidak berpuasa (p-value : 0,313). Hasil uji statistik Pearson Chi Square with Yates Correction didapatkan hubungan yang tidak bermakna antara berpuasa dengan kejadian GERD (p-value : 0,552), walaupun secara klinis ditemukan adanya kemungkinan yang berpuasa lebih berisiko 1,228 (CI 95% : 0,772 -2,088) kali untuk mencetuskan kejadian GERD. Sebagai kesimpulan, Puasa Ramadhan tidak terbukti meningkatkan gejala-gejala GERD. Perlu dilakukan penelitian lebih lanjut melalui studi longitudinal untuk tindak lanjut hasil penelitian ini.


2018 ◽  
Vol 35 (1) ◽  
Author(s):  
Iqra Arshad ◽  
Sara Mohsin ◽  
Sana Iftikhar ◽  
Tahseen Kazmi ◽  
Luqman F. Nagi

Background and Objective: Initiation of Insulin therapy during earlier stages has proved to significantly improve health outcomes among diabetics in comparison to oral medications. Not only patients but physicians are also often resistant to early initiation of insulin therapy. The objective was to assess misconceptions and barriers to early initiation of insulin therapy among diabetic patients coming to a diabetic clinic. Methods: This cross sectional study was conducted on 300 patients selected by convenience sampling arriving in Diabetes Outdoor Clinics of Mayo and Services Hospitals, Lahore during August 2017 to May 2018. The data was entered and analyzed by using SPSS version 17. Results: Out of 300 patients included in study, 39% (n= 117) were males and 61% (n=183) were females. The mean age of the participants at presentation was 48.46±13.15 years with a range of 13 to 80 years. Study participants considered it embarrassing to inject insulin in public place (p-value 0.01). The fear associated with lifelong commitment to insulin therapy once it is started, was also found statistically significant (p-value 0.001)particularly in subjects who have long duration of DM (>5 years). Conclusion: Perceptions of diabetic patients about insulin therapy are still barriers to early initiation of therapy and tend to prevail in Pakistan and around the globe. How to cite this:Arshad I, Mohsin S, Iftikhar S, Kazmi T, Nagi LF. Barriers to the early initiation of Insulin therapy among diabetic patients coming to diabetic clinics of tertiary care hospitals. Pak J Med Sci. 2019;35(1):---------. doi: https://doi.org/10.12669/pjms.35.1.237 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Temesgen Debero Mere ◽  
Tilahun Beyene Handiso ◽  
Abera Beyamo Mekiso ◽  
Markos Selamu Jifar ◽  
Shabeza Aliye Ibrahim ◽  
...  

Background.Breech deliveries have always been topical issues in obstetrics. Neonates undergoing term breech deliveries have long-term morbidity up to the school age irrespective of mode of delivery.Objective. To determine prevalence and perinatal outcomes of singleton term breech delivery.Methods. Hospital based cross-sectional study was conducted on 384 participants retrospectively. Descriptive and analytical statistics was used.Result. A total of 384 breech deliveries were included. Prevalence of singleton breech deliveries in the hospital was 3.4%. The perinatal outcome of breech deliveries was 322 (83.9%). Adverse perinatal outcome of singleton term breech delivery was significantly associated with women’s age of greater than or equal to 35 years (AOR = 2.62, 95% CI = 1.14–6.03), fully dilated cervix (AOR = 0.48, 95% CI = 0.25–0.91), ruptured membrane (AOR = 5.11, 95% CI = 2.25–11.6), and fetal weight of <2500 g (AOR = 6.77, 95% CI = 3.22–14.25).Conclusion. Entrapment of head, birth asphyxia, and cord prolapse were the most common causes of perinatal mortality. Factors like fetal weight <2500 gm, mothers of age 35 years and above, those mothers not having a fully dilated cervix, and mothers with ruptured membrane were associated with increased perinatal mortality.


2019 ◽  
Vol 35 (6) ◽  
Author(s):  
Misbah Ali ◽  
Mulazim Hussain Bukhari ◽  
Faiza Hassan ◽  
Maria Illyas

Objective: To study the clinocopathological factors and presence of Human Pappiloma Virus in ameloblastoma by immnohistochemistry. Methods: It was a cross sectional study on 50 surgical specimens of ameloblastoma, completed in six months. These were selected and processed for initial screening by H&E and then by immunohistochemistry (IHC) for detection of Human Papilloma Virus (HPV). The questionnaire was designed to study the clinicopathological factors associated in these patients. Sections of 4µm were cut, placed on special positive charged glass slides in the Department of Pathology, King Edward Medical University. It was then examined by the histopathologists for grading and scoring of these lesions. Chi Square test was used to assess the differences found in types of ameloblastomas. The p-value was smaller than 0.05 (p < 0.05). Results: The mean age of the patients (12-80 years old) was 38.6±15.1 years, with male-female ratio 2.84: 1. HPV was positive in 9 (18%), whereas negative in of 41 (82%) patients. Among the positive, reactive HPV with score-1 was 8 and score-2 was 1. According to histological variant, follicular was present in 78%, Plexiform pattern in 8%, Conventional and Desmoplastic variants in one patient each; and Cystic and Acanthomatous were seen in two and three patients respectively. The mandible was involved in 39 patients, maxilla and right maxilla involved in 4 patients each, right retromolar, cheek and angle of mandible was seen in one patient each. About 16% patients had anterior, 66% had posterior and 18% had both anterior and posterior regions involved. Among the HPV positive reactive statistically, no significant difference was found with smoking, Paan and exposure to pesticides, factory or mine (p-value > 0.05). Among HPV positive reactive patients, eight had ameloblastoma whereas, 1 had ameloblastomic fibroma. There was no statistical significance of type, location and region of tumor in HPV positivity. Conclusion: Mandible and posterior region was more commonly involved. Follicular pattern was most common. There was no effect of exposure to pesticides, factory or mine, smoke and human papilloma virus in the etiology of ameloblastoma because only 18% of patients showed the association of HPV16 doi: https://doi.org/10.12669/pjms.35.6.909 How to cite this:Ali M, Bukhari MH, Hassan F, Illyas M. Clinicopathological study of ameloblastoma and detection of human papilloma virus by immunohistochemistry. Pak J Med Sci. 2019;35(6):1691-1696. doi: https://doi.org/10.12669/pjms.35.6.909 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2020 ◽  
Vol 37 (1) ◽  
Author(s):  
Saba Saif ◽  
Samina Fida ◽  
Hala Mansoor

Objectives: To assess the knowledge and confidence of junior doctors and non-specialists in examining and making a diagnosis of patients with musculoskeletal (MSK) diseases. Methods: This was a Cross-sectional study of 121 doctors working in medical clinics at a tertiary hospital between October and December 2019. Data were collected using a questionnaire. Doctor’s awareness regarding different MSK examination methods including gait, arms, leg, spine (GALS), pediatric gait, arms, leg, spine (pGALS) and regional examination of musculoskeletal system (REMS) was noted. Undergraduate teaching of these methods and use in their daily practice was surveyed. Results: Majority of the doctors lacked awareness about different MSK examination techniques. Awareness about GALS, REMS and pGALS was 44.6%, 59.5% and 18.2% respectively. There was significant correlation of GALS/REMS awareness with the undergraduate teaching and doctor’s clinical experience (p-value <0.05). Confidence level of doctors in diagnosing patients with adult MSK pathologies was 55%. Only few doctors were satisfied with their musculoskeletal education (29%). Conclusion: The GALS examination is a useful screening tool for junior doctors and non-specialists in a direct access setting to rule out musculoskeletal problems. doi: https://doi.org/10.12669/pjms.37.1.3148 How to cite this:Saif S, Fida S, Mansoor H. Assessment of knowledge of junior doctors and non-specialists about musculoskeletal medicine. Pak J Med Sci. 2021;37(1):175-179. doi: https://doi.org/10.12669/pjms.37.1.3148 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2020 ◽  
Vol 37 (1) ◽  
Author(s):  
Mariam Danish Iqbal ◽  
Tahir Naeem ◽  
Umar Khurshid ◽  
Fatima Hameed

Objective: Globally childhood diarrheal diseases continue to be the second leading cause of death. Cryptosporidium spp are important intestinal parasites that cause diarrhea in humans and animals particularly in developing countries. This investigation was carried out to find out the frequency of cryptosporidiosis in children presenting with persistent diarrhea. Methods: Two hundred stool samples were collected in this descriptive cross-sectional study conducted at Microbiology Department, Combined Military Hospital, Lahore Pakistan between the months of July to Dec 2014. Children aged five years to 12 years who presented with persistent diarrhea were included in the study. Stool specimens were processed using the modified acid-fast staining method, and microscopically examined for Cryptosporidium infection. Results: The average age of study participants was 7.95 with a standard deviation of 2.21 years. Among the participants 66% were males whereas 34% were females. Twenty eight percent had presence of oocysts in stool samples. Conclusions: The frequency of Cryptosporidiosis among children with persistent diarrhea was 28%. This high frequency indicates that this population is uniquely susceptible to infection. It also highlights the need for education about hygiene, accurate diagnosis, and treatment of Cryptosporidiosis. There is also a need for additional studies regarding the occurrence of this pathogen. doi: https://doi.org/10.12669/pjms.37.1.2700 How to cite this:Iqbal MD, Naeem T, Khurshid U, Hameed F. Frequency of Cryptosporidiosis in Children having Persistent Diarrhea. Pak J Med Sci. 2021;37(1):121-124. doi: https://doi.org/10.12669/pjms.37.1.2700 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2021 ◽  
Vol 6 (2) ◽  
pp. 22-27
Author(s):  
Dr. Chimata Triveni ◽  
◽  
Dr. Tirumuru Divya ◽  
Dr. Ponna Rama Devi ◽  
Dr. N. Lakshmi Chowdary ◽  
...  

Introduction: Visual impairment affects students’ routine schoolwork and day-to-day activities.Hence, the aim is to study the prevalence of various refractive errors and their comparison amongschool children of 5-15 years in rural and urban areas. Methods: This cross-sectional studyexamined 998 students from both rural and urban schools. After obtaining ethical clearance andinformed consent, students were examined for refractive errors. The students with the refractiveerror were given a socio-demographic questionnaire and questionnaire regarding their usage oftelevision, computer, and family history of refractive errors. A Chi-square test was used to test thestatistical significance of proportions. P-value < 0.05 was considered statistically significant, anddata were analyzed by using coGuide software, V.1.03 Results: The prevalence of refractive errorwas found to be 6.41 %, with a prevalence of 7.61% in urban and 5.21% in rural areas. Thedifference in the type of refractive error between the study groups was found to be insignificant,with P= 0.897. Conclusion: Prevalence of refractive errors was more in urban school children thanrural. Refractive error was more prevalent in 13-15 years age group in both rural and urban schoolchildren. The most common refractive error was myopia, followed by astigmatism andhypermetropia.


2019 ◽  
Vol 35 (4) ◽  
Author(s):  
Ahmed M Ahmed

Objective: To examine concentration of Paraoxonase 1 enzymes across both Sudanese patients suffering from Type-I and Type-II diabetes. Methods: This was a cross-sectional study done in Khartoum/Sudan during the period from June 24th 2018 to August 23, 2018. One hundred seven diabetic patients (40 T1DM and 67 T2DM) compared with 45 healthy people from both genders. Biochemical parameters include PON1, FBG, HbA1C, and lipids were done and compared between study groups. Results: PON1 was reduced in patients than controls (P < 0.01), in addition PON1 was lower in T1DM than T2DM (P < 0.01), moreover, FBG, HbA1c and lipids was higher in diabetes than controls (P < 0.05). PON1 inversely correlated with LDL and apo B in T1DM (P < 0.01) and T2DM (P < 0.05), in addition PON1 correlated with HDL and apo A1 in T1DM (P < 0.01), inversely correlated with LDL in T2DM (P < 0.05) and with apo A1 in T2DM (P < 0.01). Moreover, PON1 inversely correlated with diabetes duration in T1DM (P < 0.01) and T2DM (P < 0.05). Conclusion: Sudanese T1DM and T2DM have a lower PON1 concentration than healthy subjects, T1DM have lower level of PON1 than T2DM. PON1 was inversely correlated with bad lipids and duration of diabetes, but it has positive correlation with good lipids. doi: https://doi.org/10.12669/pjms.35.4.26 How to cite this:Ahmed AM. Correlation of Paraoxonase-1 with glycated hemoglobin and lipid profile among Sudanese diabetic patients. Pak J Med Sci. 2019;35(4):---------. doi: https://doi.org/10.12669/pjms.35.4.26 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2020 ◽  
Vol 36 (7) ◽  
Author(s):  
Shireen Qassim Bham ◽  
Farhan Saeed ◽  
Muhammad Athar Khan ◽  
Rashid Naseem Khan

Objective: To assess the episodes of pneumonia and diarrhea in vaccinated and unvaccinated children under 60 months of age. Methods: This descriptive cross-sectional study was carried out at Darul Sehat Hospital and SESSI, Karachi in the Department of Pediatrics from 1st November 2018 to 3rd February 2019. An interview based questionnaire was administered and selection of participants was done by convenience sampling. Total of 196 participants were selected for interview. Results: Total 196 participants were interviewed which included mothers of children between the age group of 1- 60 months. The questions were entered on the questionnaire after taking consent from the mothers. Among them, males were 98 (52.7%) and females were 88(47.3%). One hundred seventy two (88.7%) children were vaccinated for pneumococcal and rotavirus whereas unvaccinated children were 22(11.3%). There was an incidence of 66(63.5%) for loose watery diarrhea. In vaccinated children, grading of diarrhea was found to be severe cases as 30 (34.9%), moderate cases as 27 (31.4%) and mild cases as 29(33.7%). For unvaccinated children, severe cases were 12 (66.7%) and for mild and moderate cases were (11.1%) and 04(22.2%) respectively with p value of 0.035. As compared to their unvaccinated counterparts, the frequency of severe pneumonia was far less than cough and cold in vaccinated children (p<0.001) Conclusion: There is significant reduction in cases of severe pneumonia in children receiving pneumococcal vaccine as compared to children receiving Rota vaccine there is moderate reduction in cases of severe diarrhea. The overall coverage of Pneumococcal and Rota vaccines was higher in our sample population. Efforts should be made to increase the awareness of Rotavirus vaccination in order to have better coverage in future. doi: https://doi.org/10.12669/pjms.36.7.2996 How to cite this:Bham SQ, Saeed F, Khan MA, Khan RN. Assessment of episodes of pneumonia and diarrhea in vaccinated and unvaccinated children under 60 months of age. Pak J Med Sci. 2020;36(7):---------. doi: https://doi.org/10.12669/pjms.36.7.2996 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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