scholarly journals Effect of antibiotics on bacterial populations: a multi-hierarchical selection process

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 51 ◽  
Author(s):  
José Luis Martínez
Keyword(s):  
Human Body ◽  
Selection Process ◽  
Bacterial Populations ◽  
Bacterial Physiology ◽  
Population Selection ◽  
Human Therapy ◽  
Hierarchical Selection ◽  
Available Information ◽  
Different Levels ◽  
Selection Of

Antibiotics have been widely used for a number of decades for human therapy and farming production. Since a high percentage of antibiotics are discharged from the human or animal body without degradation, this means that different habitats, from the human body to river water or soils, are polluted with antibiotics. In this situation, it is expected that the variable concentration of this type of microbial inhibitor present in different ecosystems may affect the structure and the productivity of the microbiota colonizing such habitats. This effect can occur at different levels, including changes in the overall structure of the population, selection of resistant organisms, or alterations in bacterial physiology. In this review, I discuss the available information on how the presence of antibiotics may alter the microbiota and the consequences of such alterations for human health and for the activity of microbiota from different habitats.

The Selection of Children's Books Translated from Spanish to Galician, Basque and Catalan (1940–80)

2009 ◽  
Vol 2 (2) ◽  
pp. 243-258
Author(s):  
Mónica Domínguez Pérez
Keyword(s):  
Social Economic ◽  
Children’S Literature ◽  
Status Quo ◽  
Intercultural Relations ◽  
Children's Books ◽  
Source Text ◽  
The Status ◽  
Castilian Spanish ◽  
Different Levels ◽  
Selection Of

This study deals with children's literature translated from Castilian Spanish into Galician, Basque and Catalan by a different publisher from that of the source text, between 1940 and 1980, and with the criteria used to choose books for translation during that period. It compares the different literatures within Spain and examines the intersystemic and intercultural relations that the translations reflect. Following the polysystems theory, literature is here conceived as a network of agents of different kinds: authors, publishers, readers, and literary models. Such a network, called a polysystem, is part of a larger social, economic, and cultural network. These extra-literary considerations play an important role in determining the selection of works to be translated. The article suggests that translations can be said to establish transcultural relations, and that they demonstrate different levels of power within a specific interliterary community. It concludes that, while translations may aim to change the pre-existent relationships, frequently they just reflect the status quo.

ESTIMASI NILAI HERITABILITAS BOBOT IKAN MAS VARIETAS PUNTEN DALAM PROGRAM SELEKSI INDIVIDU

2016 ◽  
Vol 11 (3) ◽  
pp. 217
Author(s):  
Estu Nugroho ◽  
Budi Setyono ◽  
Mochammad Su’eb ◽  
Tri Heru Prihadi
Keyword(s):  
Body Weight ◽  
Selection Response ◽  
Base Population ◽  
Breeding Programs ◽  
Male And Female ◽  
Body Weight Trait ◽  
Population Selection ◽  
Selection For ◽  
Weight Trait ◽  
Selection Of

Program pemuliaan ikan mas varietas Punten dilakukan dengan seleksi individu terhadap karakter bobot ikan. Pembentukan populasi dasar untuk kegiatan seleksi dilakukan dengan memijahkan secara massal induk ikan mas yang terdiri atas 20 induk betina dan 21 induk jantan yang dikoleksi dari daerah Punten, Kepanjen (delapan betina dan enam jantan), Kediri (tujuh betina dan 12 jantan), Sragen (27 betina dan 10 jantan), dan Blitar (15 betina dan 11 jantan). Larva umur 10 hari dipelihara selama empat bulan. Selanjutnya dilakukan penjarangan sebesar 50% dan benih dipelihara selama 14 bulan untuk dilakukan seleksi dengan panduan hasil sampling 250 ekor individu setiap populasi. Seleksi terhadap calon induk dilakukan saat umur 18 bulan pada populasi jantan dan betina secara terpisah dengan memilih berdasarkan 10% bobot ikan yang terbaik. Calon induk yang terseleksi kemudian dipelihara hingga matang gonad, kemudian dipilih sebanyak 150 pasang dan dipijahkan secara massal. Didapatkan respons positif dari hasil seleksi berdasarkan bobot ikan, yaitu 49,89 g atau 3,66% (populasi ikan jantan) dan 168,47 g atau 11,43% (populasi ikan betina). Nilai heritabilitas untuk bobot ikan adalah 0,238 (jantan) dan 0,505 (betina).Punten carp breeding programs were carried out by individual selection for body weight trait. The base population for selection activities were conducted by mass breeding of parent consisted of 20 female and 21 male collected from area Punten, eight female and six male (Kepanjen), seven female and 12 male (Kediri), 27 female and 10 male (Sragen), 15 female and 11 male (Blitar). Larvae 10 days old reared for four moths. Then after spacing out 50% of total harvest, the offspring reared for 14 months for selection activity based on the sampling of 250 individual each population. Selection of broodstock candidates performed since 18 months age on male and female populations separately by selecting based on 10% of fish with best body weight. Candidates selected broodstocks were then maintained until mature. In oder to produce the next generation 150 pairs were sets and held for mass spawning. The results revealed that selection response were positive, 49.89 g (3.66%) for male and 168.47 (11.43%) for female. Heritability for body weight is 0.238 (male) and 0.505 (female).

IMPLEMENTASI PENENTUAN ARSITEKTUR MASJID MODERN DI ACEH MENGGUNAKAN PEMODELAN SISTEM CERDAS

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Soraya Masthura Hasan ◽  
T Iqbal Faridiansyah
Keyword(s):  
Fuzzy Inference System ◽  
Architectural Design ◽  
Fuzzy Inference ◽  
Intelligent System ◽  
Selection Process ◽  
System Modeling ◽  
Inference System ◽  
Normal Limits ◽  
Roof Structure ◽  
Selection Of

Mosque architectural design is based on Islamic culture as an approach to objects and products from the Islamic community by looking at their suitability and values and basic principles of Islam that explore more creative and innovative ideas. The purpose of this system is to help the team and the community in seeing the best mosque in the top order so that the system can be used as a reference for the team and the community. The variables used in the selection of modern mosques include facilities and infrastructure, building structure, roof structure, mosque area, level of security and facilities. The system model used is a fuzzy promethee model that is used for the modern mosque selection process. Fuzzy inference assessment is used to determine the value of each variable so that the value remains at normal limits. Fuzzy values will then be included in promethee assessment aspects. The highest promethee ranking results will be made a priority for the best mosque ranking. This fuzzy inference system and promethee system can help the management team and the community in determining the selection of modern mosques in aceh in accordance with modern mosque architecture. Intelligent System Modeling System In Determining Modern Mosque Architecture in the City of Aceh, this building will be web based so that all elements of society can see the best mosque in Aceh by being assessed by all elements of modern mosque architecture.Keywords: Fuzzy inference system, Promethe, Option of  Masjid

Embodying the culture of achievement: Culture between illness and perfection is a ‘thin line’ – obtaining the ideal female body as an act of achievement

2021 ◽  
pp. 1354067X2110040
Author(s):  
Josefine Dilling ◽  
Anders Petersen
Keyword(s):  
Experimental Study ◽  
Human Body ◽  
Female Body ◽  
The Body ◽  
Thin Line ◽  
Complex Processes ◽  
The Individual ◽  
Different Levels ◽  
The Ideal ◽  
Body Ideals

In this article, we argue that certain behaviour connected to the attempt to attain contemporary female body ideals in Denmark can be understood as an act of achievement and, thus, as an embodiment of the culture of achievement, as it is characterised in Præstationssamfundet, written by the Danish sociologist Anders Petersen (2016) Hans Reitzels Forlag . Arguing from cultural psychological and sociological standpoints, this article examines how the human body functions as a mediational tool in different ways from which the individual communicates both moral and aesthetic sociocultural ideals and values. Complex processes of embodiment, we argue, can be described with different levels of internalisation, externalisation and materialisation, where the body functions as a central mediator. Analysing the findings from a qualitative experimental study on contemporary body ideals carried out by the Danish psychologists Josefine Dilling and Maja Trillingsgaard, this article seeks to anchor such theoretical claims in central empirical findings. The main conclusions from the study are used to structure the article and build arguments on how expectations and ideals expressed in an achievement society become embodied.

scholarly journals Cysteine Cathepsins and Their Prognostic and Therapeutic Relevance in Leukemia

2021 ◽  
Author(s):  
Mohit Arora ◽  
Garima Pandey ◽  
Shyam S. Chauhan
Keyword(s):  
Antigen Processing ◽  
Hematological Malignancies ◽  
Expression Patterns ◽  
Aberrant Expression ◽  
Hematopoietic Stem ◽  
Cysteine Cathepsins ◽  
Expression Activity ◽  
Available Information ◽  
Antigen Processing And Presentation ◽  
Selection Of

AbstractCysteine cathepsins are lysosomal proteases that require Cys-His ion pair in their catalytic site for enzymatic activity. While their aberrant expression and oncogenic functions have been widely reported in solid tumors, recent findings suggest that these proteases also play an important role in the pathogenesis of hematological malignancies. In this review, we summarize the potential clinical implications of cysteine cathepsins as diagnostic and prognostic markers in leukemia, and present evidences which supports the utility of these proteases as potential therapeutic targets in hematological malignancies. We also highlight the available information on the expression patterns, regulation, and potential functions of cysteine cathepsins in normal hematopoiesis and hematological malignancies. In hematopoiesis, cysteine cathepsins play a variety of physiological roles including regulation of hematopoietic stem cell adhesion in the bone marrow, trafficking, and maturation. They are also involved in several functions of immune cells which include the selection of lymphocytes in the thymus, antigen processing, and presentation. However, the expression of cysteine cathepsins is dysregulated in hematological malignancies where they have been shown to play diverse functions. Interestingly, several pieces of evidence over the past few years have demonstrated overexpression of cathepsins in leukemia and their association with worst survival outcomes in patients. Strategies aimed at altering the expression, activity, and subcellular localization of these cathepsins are emerging as potential therapeutic modalaties in the management of hematological malignancies. Recent findings also suggest the involvement of these proteases in modulating the immune response in leukemia and lymphomas.

scholarly journals Potential Energy Implications of Connected and Automated Vehicles: Exploring Key Leverage Points through Scenario Screening and Analysis

2019 ◽  
Vol 2673 (5) ◽  
pp. 84-94 ◽  
Author(s):  
Brian Bush ◽  
Laura Vimmerstedt ◽  
Jeff Gonder
Keyword(s):  
Systems Engineering ◽  
Large Scale ◽  
Operating Cost ◽  
Dynamics Model ◽  
Transportation Service ◽  
Service Outcomes ◽  
Behavioral Parameters ◽  
Computationally Intensive ◽  
Different Levels ◽  
Selection Of

Connected and automated vehicle (CAV) technologies could transform the transportation system over the coming decades, but face vehicle and systems engineering challenges, as well as technological, economic, demographic, and regulatory issues. The authors have developed a system dynamics model for generating, analyzing, and screening self-consistent CAV adoption scenarios. Results can support selection of scenarios for subsequent computationally intensive study using higher-resolution models. The potential for and barriers to large-scale adoption of CAVs have been analyzed using preliminary quantitative data and qualitative understandings of system relationships among stakeholders across the breadth of these issues. Although they are based on preliminary data, the results map possibilities for achieving different levels of CAV adoption and system-wide fuel use and demonstrate the interplay of behavioral parameters such as how consumers value their time versus financial parameters such as operating cost. By identifying the range of possibilities, estimating the associated energy and transportation service outcomes, and facilitating screening of scenarios for more detailed analysis, this work could inform transportation planners, researchers, and regulators.

scholarly journals Optimising the selection of food items for FFQs using Mixed Integer Linear Programming

2014 ◽  
Vol 18 (1) ◽  
pp. 68-74 ◽  
Author(s):  
Johanna C Gerdessen ◽  
Olga W Souverein ◽  
Pieter van ‘t Veer ◽  
Jeanne HM de Vries
Keyword(s):  
Linear Programming ◽  
Integer Linear Programming ◽  
Mixed Integer Linear Programming ◽  
Selection Process ◽  
Saturated Fat ◽  
Mixed Integer ◽  
Monounsaturated Fat ◽  
Food Items ◽  
Milp Model ◽  
Selection Of

AbstractObjectiveTo support the selection of food items for FFQs in such a way that the amount of information on all relevant nutrients is maximised while the food list is as short as possible.DesignSelection of the most informative food items to be included in FFQs was modelled as a Mixed Integer Linear Programming (MILP) model. The methodology was demonstrated for an FFQ with interest in energy, total protein, total fat, saturated fat, monounsaturated fat, polyunsaturated fat, total carbohydrates, mono- and disaccharides, dietary fibre and potassium.ResultsThe food lists generated by the MILP model have good performance in terms of length, coverage and R2 (explained variance) of all nutrients. MILP-generated food lists were 32–40 % shorter than a benchmark food list, whereas their quality in terms of R2 was similar to that of the benchmark.ConclusionsThe results suggest that the MILP model makes the selection process faster, more standardised and transparent, and is especially helpful in coping with multiple nutrients. The complexity of the method does not increase with increasing number of nutrients. The generated food lists appear either shorter or provide more information than a food list generated without the MILP model.

Relationship between glycated hemoglobin and glucose concentrations in the adult Galician population: selection of optimal glycated hemoglobin cut-off points as a diagnostic tool of diabetes mellitus

2012 ◽  
Vol 59 (8) ◽  
pp. 496-504 ◽  
Author(s):  
Manuel Antonio Botana López ◽  
Mónica López Ratón ◽  
María Ausencia Tomé ◽  
Alexis Fernández Mariño ◽  
José Antonio Mato Mato ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diagnostic Tool ◽  
Glycated Hemoglobin ◽  
Population Selection ◽  
Selection Of

Research on Material Selection with Multi-Attribute Decision Method and G1 Method

2014 ◽  
Vol 952 ◽  
pp. 20-24 ◽  
Author(s):  
Xue Jun Xie
Keyword(s):  
Material Selection ◽  
Selection Process ◽  
Selection Problem ◽  
Topsis Method ◽  
Attribute Weight ◽  
Multi Attribute Decision Making ◽  
Judgment Matrix ◽  
Optimal Material ◽  
Selection Of ◽  
Better Than

The selection of an optimal material is an important aspect of design for mechanical, electrical, thermal, chemical or other application. Many factors (attributes) need to be considered in material selection process, and thus material selection problem is a multi-attribute decision making (MADM) problem. This paper proposes a new MADM method for material selection problem. G1 method does not need to test consistency of the judgment matrix. Thus it is better than AHP. In this paper, firstly, we use the G1 method to determine the attribute weight. Then TOPSIS method is used to calculate the closeness of the candidate materials with respect positive solution. A practical material selection case is used to demonstrate the effectiveness and feasibility of the proposed method.

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