scholarly journals How to evaluate the capacity of hospital systems in a very long term international comparative perspective? Hospital beds per inhabitant in Catalonia 1900s-2010s

2021 ◽  
Vol 6 (1) ◽  
pp. 182-226
Author(s):  
Paloma Fernández Pérez
Keyword(s):  
20Th Century ◽  
World Health Organisation ◽  
World Health ◽  
Western World ◽  
Hospital Beds ◽  
The World ◽  
Hospital Systems ◽  
Per Capita ◽  
International Comparative

This article proposes that the number of hospital beds available in a territory can be used as a comparative tool to gain a perspective on the very long term evolution of the historical capacity of hospital systems worldwide. The article presents: 1) the issues stemming from a lack of sources and comparative data available internationally before 1960; 2) data for the early 20th century for Barcelona and other cities of the world,; 3) data on hospital beds for various countries since the 1960s, with attention to data for Catalonia,; 4) data for the number of hospital beds per 1000 inhabitants for the past few decades in Catalonia, and a comparison with other autonomous communities and countries. The sources are the League of Nations, Yearbooks for Barcelona, the National Statistics Institute of Spain (Instituto Nacional de Estadística, INE), IDESCAT, the World Health Organisation (WHO) and the OECD. The article provides research data that confirm that the beginning of the modern increase in the number of hospital beds per capita in Catalonia started as the rest of the Western world in the first third of the 20th century. Such growth was maintained throughout the 20th century up until the 1980s. After the 1980s, in Barcelona as in the rest of the world, there was a process of reducing hospital beds per capita. This has therefore created the possibility of hospital services being overwhelmed very quickly in the instance of a widespread health emergency.

Global lessons from Ebola crisis may be ignored

2015 ◽  
Keyword(s):  
Health Services ◽  
World Health Organisation ◽  
World Health ◽  
Health Priorities ◽  
Local Health ◽  
International Organisations ◽  
Content Type ◽  
The World ◽  
National Governments

Subject Lessons from the Ebola crisis. Significance The Ebola epidemic in West Africa caught national governments and international organisations off-guard. As the epidemic begins to abate in the affected countries, the World Health Organisation (WHO) has begun an internal process to learn lessons for future global health emergencies. However, many of the required responses were well-known before the Ebola outbreak but ignored. Shifting entrenched political attitudes will be a challenge. Impacts Popular distrust of local health services continues to mar comprehensive detection of Ebola infections in affected countries. Re-building local health services will be distorted if the Ebola crisis dominates planning over long-term health priorities. However, donors tend to prefer orientation towards disease-specific programmes and interventions over strengthening health systems.

scholarly journals Global health in the making: health demonstration areas in Europe, 1950s and 1960s

2020 ◽  
Vol 27 (suppl 1) ◽  
pp. 165-185
Author(s):  
Esteban Rodríguez-Ocaña
Keyword(s):  
Health Services ◽  
Global Health ◽  
State Of The Art ◽  
World Health Organisation ◽  
World Health ◽  
Primary Health ◽  
The World ◽  
Historical Importance ◽  
Standardization Of Procedures

Abstract Global health is a multifaceted concept that entails the standardization of procedures in healthcare domains in accordance with a doctrine agreed upon by experts. This essay focus on the creation of health demonstration areas by the World Health Organisation (WHO) to establish core nodes for integrated state-of-the-art health services. It explores the origins, theoretical basis and aims of this technique and reviews several European experiences during the first 20 years of the WHO. Particular attention is paid to the historical importance of technical cooperative activities carried out by the WHO in regard to the implementation of health services, a long-term strategic move that contributed to the thematic upsurge of primary health care in the late 1970s.

Body Mass Index and Weight Distribution

2009 ◽  
Vol 54 (3) ◽  
pp. 17-21 ◽  
Author(s):  
Cdr Pengelly ◽  
J Morris
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
World Health Organisation ◽  
World Health ◽  
Insurance Companies ◽  
Life Assurance ◽  
The World ◽  
Hip Measurements

It has been accepted for many years that being overweight or obese, as indicated by a body mass index (BMI) of 25 or over for the former and 30 or over for the latter, is associated with impairment of long term health and prognosis. The World Health Organisation (WHO) has indicated that, in Caucasians, waist measurements of 94cm or more in men, and 80cm or more in women have similar adverse effects on health, with increased risks at 102 cm or more in men and 88 cm in women. The role of waist-hip ratio (W/H) and whether it represents a better index than waist (W) measurement alone is being debated; many papers favour waist measurement alone. But two papers in 2005 discussing 27,098 subjects, 12,461 of whom had myocardial infarction and 14,637 controls, come down firmly in favour of W/H and were followed by a Lancet Editorial entitled ‘Farewell to Body Mass Index?’ Life assurance companies at medical examination usually request height and weight measurements (and therefore BMI). Most ask for waist measurements and a few hip measurements in addition (and therefore W/H). The authors have reviewed the data in 816 consecutive subjects for life assurance examination in whom BMIs, Ws and W/Hs were all recorded. In these the evidence supports the use of W as the best indicator of risk in men (634 cases), but not in the relatively small number of women (182 cases) in whom H appeared better. We believe that BMI, W and W/H should be recorded in every subject at life assurance examination so that the insurance companies in the long term will be able to reach valid conclusions about their individual and collective value

A Collaborative Study to Establish the Second International Standard for Streptokinase

1990 ◽  
Vol 64 (02) ◽  
pp. 267-269 ◽  
Author(s):  
A B Heath ◽  
P J Gaffney
Keyword(s):  
High Purity ◽  
Collaborative Study ◽  
World Health Organisation ◽  
World Health ◽  
Clot Lysis ◽  
Current Standard ◽  
International Standard ◽  
Accelerated Degradation ◽  
The World ◽  
International Collaborative Study

SummaryAn International Standard for Streptokinase - Streptodomase (62/7) has been used to calibrate high purity clinical batches of SK since 1965. An international collaborative study, involving six laboratories, was undertaken to replace this standard with a high purity standard for SK. Two candidate preparations (88/826 and 88/824) were compared by a clot lysis assay with the current standard (62/7). Potencies of 671 i.u. and 461 i.u. were established for preparations A (88/826) and B (88/824), respectively.Either preparation appeared suitable to serve as a standard for SK. However, each ampoule of preparation A (88/826) contains a more appropriate amount of SK activity for potency testing, and is therefore preferred. Accelerated degradation tests indicate that preparation A (88/826) is very stable.The high purity streptokinase preparation, coded 88/826, has been established by the World Health Organisation as the 2nd International Standard for Streptokinase, with an assigned potency of 700 i.u. per ampoule.

Comparative docking of SARS-CoV-2 receptors antagonists from repurposing drugs

2020 ◽  
Author(s):  
Micael Davi Lima de Oliveira ◽  
Kelson Mota Teixeira de Oliveira
Keyword(s):  
World Health Organisation ◽  
World Health ◽  
Lung Cells ◽  
The Novel ◽  
High Modulation ◽  
Main Protease ◽  
The World ◽  
Novel Coronavirus ◽  
Viral Receptors ◽  
Theoretical Results

According to the World Health Organisation, until 16 June, 2020, the number of confirmed and notified cases of COVID-19 has already exceeded 7.9 million with approximately 434 thousand deaths worldwide. This research aimed to find repurposing antagonists, that may inhibit the activity of the main protease (Mpro) of the SARS-CoV-2 virus, as well as partially modulate the ACE2 receptors largely found in lung cells, and reduce viral replication by inhibiting Nsp12 RNA polymerase. Docking molecular simulations were performed among a total of 60 structures, most of all, published in the literature against the novel coronavirus. The theoretical results indicated that, in comparative terms, paritaprevir, ivermectin, ledipasvir, and simeprevir, are among the most theoretical promising drugs in remission of symptoms from the disease. Furthermore, also corroborate indinavir to the high modulation in viral receptors. The second group of promising drugs includes remdesivir and azithromycin. The repurposing drugs HCQ and chloroquine were not effective in comparative terms to other drugs, as monotherapies, against SARS-CoV-2 infection.

Use of Phosphatidylcholine in the Treatment of Localized Fat Deposits. Results and expectations

2017 ◽  
Vol 68 (7) ◽  
pp. 1438-1441 ◽  
Author(s):  
Sorin Berbece ◽  
Dan Iliescu ◽  
Valeriu Ardeleanu ◽  
Alexandru Nicolau ◽  
Radu Cristian Jecan
Keyword(s):  
World Health Organisation ◽  
Normal Weight ◽  
World Health ◽  
Basic Substance ◽  
Physical Exercises ◽  
Fat Deposits ◽  
The World ◽  
The Common ◽  
Global Health Problem ◽  
Over Time

Obesity represents a global health problem. According to the latest studies released by the World Health Organisation (WHO), 1.7 billion currently in excess of normal weight individuals, of which approx. 75% are overweight (body mass index - BMI 25 to 30). The common form of excess adipose tissue manifestation in overweight individuals is localized fat deposits with high (abdominal) or low (buttocks and thighs) disposition. Although the overweight can be corrected relatively easy by changing behavioral habits or food, a constant physical exercises program or following a diet food are not accessible to all through the efforts of will, financial and time involved. Several methods have been studied and tested over time to eliminate more or less invasive fat deposits with varying efficacy and adverse effects. Chemical lipolysis using phosphatidylcholine as the basic substance was initially used in hypercholesterolemia and its complications and was rapidly adopted in mesotherapy techniques for the treatment of fat deposits. This study reveals the results obtained using Dermastabilon on a sample of 16 patients, the time allocated to treatment and discomfort being minimal, and rapid and notable results. There were no side effects.

The Undiscovered Potential of Essential Oils for Treating SARS-CoV-2 (COVID-19)

2020 ◽  
Vol 26 (41) ◽  
pp. 5261-5277
Author(s):  
Peter J. Wilkin ◽  
Minnatallah Al-Yozbaki ◽  
Alex George ◽  
Girish K. Gupta ◽  
Cornelia M. Wilson
Keyword(s):  
Essential Oils ◽  
Clinical Symptoms ◽  
Synergistic Effects ◽  
World Health Organisation ◽  
Diagnostic Techniques ◽  
World Health ◽  
Clinical Aspects ◽  
Traditional Use ◽  
In Silico Studies ◽  
The World

On 11th March 2020, the World Health Organisation (WHO) announced a pandemic caused by a novel beta-coronavirus SARS-CoV-2, designated COVID-19. The virus emerged in December 2019 in Wuhan, China, has spread across the world as a global pandemic. The traditional use of medicines from plants can be traced back to 60,000 years. Global interest in the development of drugs from natural products has increased greatly during the last few decades. Essential oils (EOs) have been studied through the centuries and are known to possess various pharmaceutical properties. In the present review, we have highlighted the current biology, epidemiology, various clinical aspects, different diagnostic techniques, clinical symptoms, and management of COVID-19. An overview of the antiviral action of EOs, along with their proposed mechanism of action and in silico studies conducted, is described. The reported studies of EOs' antiviral activity highlight the baseline data about the additive and/or synergistic effects among primary or secondary phytoconstituents found in individual oils, combinations or blends of oils and between EOs and antiviral drugs. It is hoped that further research will provide better insights into EOs' potential to limit viral infection and aid in providing solutions through natural, therapeutically active agents.

Infodemiological patterns in searching medication errors: relationship with risk management and shift work (Preprint)

2019 ◽  
Author(s):  
Fabio Fabbian ◽  
Emanuele Di Simone ◽  
Sara Dionisi ◽  
Noemi Giannetta ◽  
Luigi De Gennaro ◽  
...  
Keyword(s):  
Health Care ◽  
Risk Management ◽  
Shift Work ◽  
Medication Errors ◽  
Medical Errors ◽  
World Health ◽  
Noncommunicable Diseases ◽  
Western World ◽  
The World ◽  
Google Search

BACKGROUND Western world health care systems have been trying to improve their efficiency and effectiveness in order to respond properly to the aging of the population and the epidemic of noncommunicable diseases. Errors in drugs administration is an actual important issue due to different causes. OBJECTIVE Aim of this study is to measure interest in online seeking medical errors information online related to interest in risk management and shift work. METHODS We investigated Google Trends® for popular search relating to medical errors, risk management and shift work. Relative search volumes (RSVs) were evaluated for the period November 2008-November 2018 all around the world. A comparison between RSV curves related to medical errors, risk management and shift work was carried out. Then we compared world to Italian search. RESULTS RSVs were persistently higher for risk management than for medication errors during the study period (mean RSVs 74 vs. 51%) and RSVs were stably higher for medical errors than shift work during the study period (mean RSVs 51 vs 23%). In Italy, RSVs were much lower than the rest of the world, and RSVs for medication errors during the study period were negligible. Mean RSVs for risk management and shift work were 3 and 25%, respectively. RSVs related to medication errors and clinical risk management were correlated (r=0.520, p<0.0001). CONCLUSIONS Google search query volumes related to medication errors, risk management and shift work are different. RSVs for risk management are higher, are correlated with medication errors, and the relationship with shift work appears to be even worse, by analyzing the entire world. In Italy such a relationship completely disappears, suggesting that it needs to be emphasized by health care authorities.

scholarly journals Seroprevalence of SARS-CoV-2, Symptom Profiles and Sero-Neutralization in a Suburban Area, France

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1076
Author(s):  
Anne Gégout Petit ◽  
Hélène Jeulin ◽  
Karine Legrand ◽  
Nicolas Jay ◽  
Agathe Bochnakian ◽  
...  
Keyword(s):  
Odds Ratio ◽  
World Health Organisation ◽  
World Health ◽  
Preventive Effect ◽  
Neutralization Activity ◽  
Symptom Profiles ◽  
The World ◽  
Household Members ◽  
Total Immunoglobulin

The World Health Organisation recommends monitoring the circulation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We investigated anti–SARS-CoV-2 total immunoglobulin (IgT) antibody seroprevalence and in vitro sero-neutralization in Nancy, France, in spring 2020. Individuals were randomly sampled from electoral lists and invited with household members over 5 years old to be tested for anti–SARS-CoV-2 (IgT, i.e., IgA/IgG/IgM) antibodies by ELISA (Bio-rad); the sero-neutralization activity was evaluated on Vero CCL-81 cells. Among 2006 individuals, the raw seroprevalence was 2.1% (95% confidence interval 1.5 to 2.9), was highest for 20- to 34-year-old participants (4.7% (2.3 to 8.4)), within than out of socially deprived area (2.5% vs. 1%, p = 0.02) and with than without intra-family infection (p < 10−6). Moreover, 25% of participants presented at least one COVID-19 symptom associated with SARS-CoV-2 positivity (p < 10−13), with highly discriminant anosmia or ageusia (odds ratio 27.8 [13.9 to 54.5]); 16.3% (6.8 to 30.7) of seropositive individuals were asymptomatic. Positive sero-neutralization was demonstrated in vitro for 31/43 seropositive subjects. Regarding the very low seroprevalence, a preventive effect of the lockdown in March 2020 can be assumed for the summer, but a second COVID-19 wave, as expected, could be subsequently observed in this poorly immunized population.

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