scholarly journals From resistance to persistence: Insights of a mathematical model on the indiscriminate use of insecticide

2020 ◽  
Vol 14 (11) ◽  
pp. e0008862
Author(s):  
Helio Schechtman ◽  
Denise Valle ◽  
Max O. Souza

The development of insecticide resistance is becoming a threat to many arboviruses control programs worldwide. While this has been attributed to the indiscriminate use of insecticide, a more theoretical study is apparently not available. Using in-silico experiments, we investigated the effects of two different policies: one used by the Brazilian Ministry of Health (which follows the World Health Organization protocol) and a more permissive one, akin to those employed by various gated communities and private companies. The results show that the public policy does not lead to resistance fixation. On the other hand, permissive application of adulticide, such as intensive domestic use mainly during epidemic periods, might lead to the fixation of a resistant population, even when resistance is associated with moderate fitness costs.

Author(s):  
Susan Igras ◽  
Marina Plesons ◽  
Venkatraman Chandra-Mouli

Abstract Over the past 25 years, there has been significant progress in increasing the recognition of, resources for, and action on adolescent health, and adolescent sexual and reproductive health (ASRH) in particular. As with numerous other health areas, however, many of the projects that aim to improve ASRH are implemented without well-thought-out plans for evaluation. As a result, the lessons that projects learn as they encounter and address policy and programmatic challenges are often not extracted and placed in the public arena. In such cases, post-project evaluation (PPE) offers the possibility to generate learnings about what works (and does not work), to complement prospective studies of new or follow-on projects. To fill the gap in the literature and guidance on PPE, the World Health Organization developed The project has ended, but we can still learn from it! Practical guidance for conducting post-project evaluations of adolescent sexual and reproductive health projects. This article provides an overview of the guidance by outlining key methodological and contextual challenges in conducting PPE, as well as illustrative solutions for responding to them.


2018 ◽  
Vol 7 ◽  
Author(s):  
Christine Peta

In 2016, the World Health Organization, through the Global Cooperation on Assistive Technology Initiative, issued the Priority Assistive Products List which is meant to be a guide to member states of the 50 assistive products needed for a basic health care and/or social welfare system; it is also a model from which nations can develop their national priority assistive products lists. The aim of this opinion paper is to share my views about the Priority Assistive Products List on the grounds that it makes no distinct mention of sexual assistive devices, yet research has indicated that sexuality is an area of great concern for persons with disabilities. In any case, sexuality forms a core part of being human, and it impacts on both the physical and mental well-being of all human beings. I conclude in part that, in its present format, the list perpetuates the myth that persons with disabilities are asexual beings who are innocent of sexual thoughts, feelings and experiences. The list also propagates the stereotype that sexuality is a sacred, private, bedroom matter that should be kept out of the public domain, to the detriment of the health and well-being of persons with disabilities.


2010 ◽  
Vol 138 (3-4) ◽  
pp. 225-229
Author(s):  
Gorica Sbutega-Milosevic ◽  
Zorica Djordjevic ◽  
Zoran Marmut ◽  
Boban Mugosa

Introduction. Combating nutritional deficiencies of micronutrients, such as iodine, represents a priority task of health care organizations. In 2003, the World Health Organization (WHO) published the publication: Global Prevalence of Iodine Deficiency Disorders (IDD), according to which some 2,2 billion people live in areas poor in naturally occurring iodine. Approximately 13% of the world population suffer from goitre - one of the IDD. The recommended iodine content in table salt is 20-40 mg/kg, which should satisfy the daily iodine requirements of an adult. Objective. The authors sought to ascertain whether iodization of table salt in Montenegro was carried out in accordance with the existing legislature. An assessment was also carried out of the attitudes and habits of the population regarding the use of salt in nutrition and the level of awareness in relation to the relevance of table salt iodization. Methods. The research was carried out in 2004 and was sponsored by UNICEF. A sample of 594 homes from the municipalities of Bar and Podgorica was chosen: 354 homes from urban and 240 from rural areas. The participants completed a questionnaire related to the daily use and intake of salt, as well as their understanding of the relevance of table salt iodization. Iodine content was tested in 15 samples of table salt at production level, 170 samples at retail level and 126 samples taken from domestic use. Results. The analysis of table salt samples showed an optimal iodine level in 73.3% of samples from production, in 81.2% from retail, and in 73.0% from domestic use. A lower level of iodine was found in 8.8% retail samples and 15.1% samples from home use. A greater concentration of iodine was found in 26.7% production, 10.0% retail and 11.9% samples from domestic use. Conclusion. Although the application of the WHO programme has led to an improvement in iodization of table salt in Montenegro, both at production and retail levels, this still falls short of the standards recommended by WHO to combat IDD. The levels of iodine in table salt in domestic use also fail to comply with the WHO criteria for elimination of IDD.


2021 ◽  
Author(s):  
Peter chew

Abstract Background: The World Health Organization (WHO) said the situation in India was a "devastating reminder" of what the coronavirus could do. India shifts from mass vaccine exporter to importer, worrying the world. Every country needs to vaccinate its citizens faster, vaccination can reduce viral load. This results in vaccination that can reduce transmission, preventing serious illness and death'. Therefore, Countries with higher levels of vaccination can prevent them from becoming "Second India".Preprint study, Vaccination Education App (1). [Peter Chew, 2021] shows that most people do not take the covid-19 vaccine because they question the safety and effectiveness of the vaccine. Therefore, it is important to create a simple formula for calculate the efficiency of the covid-19 vaccine. The purpose of creating this calculation formula is to allow the public to calculate the efficiency of the covid-19 vaccine by themselves, so that they can understand the effectiveness of the vaccine and decide to take the vaccine. This helps to get a high response to COVID vaccinationMethods: Use the Data publish at The New England JOURNAL of MEDICINE, Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine [Fernando P. Polack et all , 2020]. Calculate of Pfizer BioNTech’s COVID-19 vaccine efficiency by using normal formular and Peter Chew Formular , show that the same result are obtain, which is 95.0599 %. In addition, By using public news information, the public can use the Peter Chew formula to easily calculate Covid-19 vaccine efficacy. This is to ensure public can do the calculation themselves. A calculation of relative risk is also provided to provide more information to persuade the public to take the vaccine.Results: The efficiency of Pfizer BioNTech's COVID-19 vaccine for Malaysian medical worker calculated by using the Peter Chew formula is 95.0599 %. In addition, the calculation of Peter Chew's formula also shows that before the vaccination, about 12 medical staff were infected every day, but after the full vaccination, only about one medical worker was infected every two days. The calculation of relative risk can also make it easier for the public to know that people who are not vaccinated with Pfizer BioNTech's COVID-19 vaccine are 22 times more likely to be infected than people who are fully vaccinated. The above results can convince those who easily question the effectiveness of vaccination.Conclusions: Peter Chew Formular easy to calculate, and the data required for the Peter Chew Formular calculation easy to obtain from public news. This is to ensure that the public can calculate the efficacy of the vaccine by themselves. The information on the calculation can let public compare the average target group get infected every day before and after fully vaccination is also an advantage to let public know the effectiveness of vaccination. One of the advantage of Peter Chew formulator is that we can assume a high target population of vaccination with k = 100, such as the medical worker group When k = 100, the Peter Chew formular calculation becomes very simple. The Proof of Peter Chew Formular must also be shown.


2008 ◽  
Vol 13 (16) ◽  
Author(s):  
Collective WHO

The World Health Organization (WHO) Regional Office for Europe established the European Immunization Week (EIW, http://www.euro.who.int/vaccine) in 2005 for three reasons: 1) to raise public awareness of the benefits of immunisation, 2) to support national immunisation systems, and 3) to provide a framework for mobilising public and political support for governmental efforts to protect the public through universal childhood immunisation.


2021 ◽  
Vol 01 ◽  
Author(s):  
Yung Chin Shih

Background: In 2019, when the World Health Organization (WHO) declared COVID-19 (Coronavirus 2019) a pandemic, many of the public managers faced tough situations in their cities due to the simultaneous loss of lives and jobs. In this regard, this study aims to propose a concise model that considers variables like the number of deaths, lethality of the virus, number of jobs and taxes collected by city halls, among others. Our study considers these issues in providing a relevant response and consistent answer to deliberations on the way forward. Method: Mathematical modeling was used to analyze the interaction between the agents involved and computer simulation was chosen to collect results. Results: - Changing the lockdown level (fixed and variable), the results of number of death per week, total number of unemployed, cost of companies and so on are shown. - The results show that for the input data considered, the 0% lockdown (LD) policy is more effective for the economy and tax collection and also succeeds in repressing the effects on the number of deaths. Because of it, the comparison between with pandemic and without pandemic is provided (in percentage). Conclusion: This study shows that implementing the lockdown did not bring expected benefits, because instead of reducing the number of deaths due to the COVID-19, individuals tend to die more from other causes.


2018 ◽  
Vol 2 ◽  
pp. 35 ◽  
Author(s):  
Danielle Cazabon ◽  
Tripti Pande ◽  
Sandra Kik ◽  
Wayne Van Gemert ◽  
Hojoon Sohn ◽  
...  

Background: Xpert® MTB/RIF, a rapid tuberculosis (TB) molecular test, was endorsed by the World Health Organization in 2010. Since then, 34.4 million cartridges have been procured under concessional pricing. Although the roll out of this diagnostic is promising, previous studies showed low market penetration. Methods: To assess 3-year trends of market penetration of Xpert MTB/RIF in the public sector, smear and Xpert MTB/RIF volumes for the year 2016 were assessed and policies from 2014-2016 within 22 high-burden countries (HBCs) were studied. A structured questionnaire was sent to representatives of 22 HBCs. The questionnaires assessed the total smear and Xpert MTB/RIF volumes, number of modules and days of operation of GeneXpert machines in National TB Programs (NTPs). Data regarding the use of NTP GeneXpert machines for other diseases and GeneXpert procurement by other disease control programs were collected. Market penetration was estimated by the ratio of total sputum smear volume for initial diagnosis divided by the number of Xpert MTB/RIF tests procured in the public sector. Results: The survey response rate was 21/22 (95%). Smear/Xpert ratios decreased in 17/21 countries and increased in four countries, since 2014. The median ratio decreased from 32.6 (Q1:14.3, Q3: 58.9) in 2014 to 6.0 (Q1: 1.6, Q3: 17.0) in 2016. Nineteen countries (19/19; 100%) were not using GeneXpert machines to their full capacity, however seven countries (7/19; 37%) were running tests for other diseases on their NTP-procured GeneXpert systems in 2017, such as HIV, hepatitis-C virus (HCV), Chlamydia trachomatis, and Neisseria gonorrhoeae. Five (5/15; 33%) countries reported GeneXpert procurement by HIV or HCV programs in 2016 and/or 2017. Conclusions: Our results show a positive trend for Xpert MTB/RIF market penetration in 21 HBC public sectors. However, GeneXpert machines were under-utilized for TB, and inadequately exploited as a multi disease technology.


Author(s):  
Martina Barchitta ◽  
Annalisa Quattrocchi ◽  
Andrea Maugeri ◽  
Maria Clara La Rosa ◽  
Claudia La Mastra ◽  
...  

The issue of antimicrobial resistance (AMR) is a focus of the World Health Organization, which proposes educational interventions targeting the public and healthcare professionals. Here, we present the first attempt at a regionwide multicomponent campaign in Sicily (Italy), called “Obiettivo Antibiotico”, which aims to raise the awareness of prudent use of antibiotics in the public and in healthcare professionals. The campaign was designed by an interdisciplinary academic team, and an interactive website was populated with different materials, including key messages, letters, slogans, posters, factsheets, leaflets, and videos. The campaign was launched in November 2018 and, as of 21 December 2018, the website had a total of 1159 unique visitors, of which 190 became champions by pledging to take simple actions to support the fight against AMR. Data from social media showed that the audience was between 18 and 54 years of age, with a high proportion of female participants (64%). Interestingly, the LinkedIn page received more than 1200 followers, and Facebook 685 followers. The number of actions taken (pledges) by the audience was 458, evenly divided between experts (53%) and the general public (47%). Additional efforts are needed to reach more people, thus future efforts should focus on further promotion within the Sicilian region to sustain the engagement with the campaign.


2020 ◽  
Vol 11 (2) ◽  
pp. 52-55
Author(s):  
Husnul Khotimah ◽  
Tijaniyah

Self-medication, known as self-medication, has now been widely used by people to treat their own diseases without a doctor's prescription. This is because the cost of examining and just consulting a doctor is very expensive for the community. According to the World Health Organization (WHO) self-medication is defined as the selection and use of drugs, including herbal and traditional medicine, by individuals to treat themselves from disease or symptoms of disease. As well as the world of digital information is currently mushrooming in various information systems to provide information to the public in real time. Therefore, the author will make a research on how web-based information systems can provide information to the public about self-medication for coughs and colds, which people often suffer from. The Multi Attribute Decision Making (MADM) method is one of the superior methods for calculating the parameters for drug decisions that can be consumed by the public, making it easier for people to choose the type of medicine according to the disease they are suffering


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