scholarly journals Structural characterization of four different naturally occurring porcine collagen membranes suitable for medical applications

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0205027 ◽  
Author(s):  
Thimo Maurer ◽  
Michael H. Stoffel ◽  
Yury Belyaev ◽  
Niklaus G. Stiefel ◽  
Beatriz Vidondo ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Medical Applications ◽  
Naturally Occurring ◽  
Collagen Membranes ◽  
Porcine Collagen

Development and characterization of electrospun curcumin-loaded antimicrobial nanofibrous membranes

2020 ◽  
pp. 004051752092551
Author(s):  
Javeed A Awan ◽  
Saif Ur Rehman ◽  
Muhammad Kashif Bangash ◽  
Fiaz Hussain ◽  
Jean-Noël Jaubert
Keyword(s):  
Biological Activities ◽  
Research Work ◽  
Medical Applications ◽  
Electrospinning Technique ◽  
Naturally Occurring ◽  
Wide Range ◽  
Nanofibrous Membranes ◽  
Antimicrobial Barrier ◽  
Anti Hiv

Curcumin is a naturally occurring hydrophobic polyphenol compound. It exhibits a wide range of biological activities such as antibacterial, anti-inflammatory, anti-carcinogenic, antifungal, anti-HIV, and antimicrobial activity. In this research work, antimicrobial curcumin nanofibrous membranes are produce by an electrospinning technique using the Eudragit RS 100 (C19H34ClNO6) polymer solution enriched with curcumin. The morphology and chemistry of the membrane are analyzed using scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. Kirby Bauer disk diffusion tests are carried out to examine the antibacterial effectiveness of the membrane. Experimental results show that the nanofibers produced are of uniform thickness morphology and curcumin is successfully incorporated into the nanofibrous mat, while no chemical bonding was observed between curcumin and the polymer. The antimicrobial curcumin nanofibrous membranes can be effectively applied as antimicrobial barrier in a wide variety of medical applications such as wound healing, scaffolds, and tissue engineering.

scholarly journals Structural characterization of naturally occurring RNA single mismatches

2010 ◽  
Vol 39 (3) ◽  
pp. 1081-1094 ◽  
Author(s):  
Amber R. Davis ◽  
Charles C. Kirkpatrick ◽  
Brent M. Znosko
Keyword(s):  
Structural Characterization ◽  
Naturally Occurring

scholarly journals Complexes of Lapachol and Lawsone with Lanthanides

2015 ◽  
Vol 10 (11) ◽  
pp. 1934578X1501001
Author(s):  
Salvatore Genovese ◽  
Vito Alessandro Taddeo ◽  
Francesco Epifano ◽  
Serena Fiorito
Keyword(s):  
Transition Metals ◽  
Structural Characterization ◽  
Preliminary Data ◽  
Short Communication ◽  
Naturally Occurring ◽  
Cytotoxic Compounds ◽  
First Time

Naturally occurring 2-hydroxy-1,4-naphthoquinones are well known to form readily stable complexes with transition metals. In this short communication we describe for the first time the synthesis and preliminary data about structural characterization of complexes between two naturally widespread 2-hydroxy-1,4-naphthoquinones, namely lapachol (1) and lawsone (2), with selected lanthanides like lanthanum, gadolinium, and ytterbium. When tested as cytotoxic compounds, such complexes exhibited an activity that was either higher or equal to that of the parent naphthoquinone.

scholarly journals The X-ray structure of human P-cadherin EC1-EC2 in a closed conformation provides insight into the type I cadherin dimerization pathway

2015 ◽  
Vol 71 (4) ◽  
pp. 371-380 ◽  
Author(s):  
Andrea Dalle Vedove ◽  
Anna Paola Lucarelli ◽  
Valentina Nardone ◽  
Angelica Matino ◽  
Emilio Parisini
Keyword(s):  
Structural Characterization ◽  
Adherens Junction ◽  
Large Family ◽  
Type I ◽  
Calcium Dependent ◽  
Closed Conformation ◽  
Naturally Occurring ◽  
Packing Arrangement

Cadherins are a large family of calcium-dependent proteins that mediate cellular adherens junction formation and tissue morphogenesis. To date, the most studied cadherins are those classified as classical, which are further divided into type I or type II depending on selected sequence features. Unlike other members of the classical cadherin family, a detailed structural characterization of P-cadherin has not yet been fully obtained. Here, the high-resolution crystal structure determination of the closed form of human P-cadherin EC1-EC2 is reported. The structure shows a novel, monomeric packing arrangement that provides a further snapshot in the yet-to-be-achieved complete description of the highly dynamic cadherin dimerization pathway. Moreover, this is the first multidomain cadherin fragment to be crystallized and structurally characterized in its closed conformation that does not carry any extra N-terminal residues before the naturally occurring aspartic acid at position 1. Finally, two clear alternate conformations are observed for the critical Trp2 residue, suggestive of a transient, metastable state. The P-cadherin structure and packing arrangement shown here provide new and valuable information towards the complete structural characterization of the still largely elusive cadherin dimerization pathway.

Composition of Color Substances of Hevea Brasiliensis Natural Rubber

2007 ◽  
Vol 80 (2) ◽  
pp. 212-230 ◽  
Author(s):  
Jitladda Sakdapipanich ◽  
Kittipong Insom ◽  
Nataphon Phupewkeaw
Keyword(s):  
Fatty Acids ◽  
High Resolution ◽  
Natural Rubber ◽  
Structural Characterization ◽  
Unsaturated Fatty Acids ◽  
Rubber Latex ◽  
Naturally Occurring ◽  
Bottom Fraction ◽  
Light Color

Abstract It is accepted that NR gives naturally occurring color, which restrict many applications such as light-color products. Therefore, characterization of color substances presenting in NR is very useful to develop the certain methodology to eliminate them completely or partly from NR in the future. In this work, an attempt was made to purify and characterize the color substances extracted from various fractions of Hevea rubber latex by certain methods, using high-resolution structural characterization techniques. It was found that the content of color substances extracted from fresh latex (FL), rubber cream, bottom fraction (BF), Frey Wyssling (FW) particles and STR 20 were different. Based on the high-resolution spectroscopic analyzes, it was found that the color substances extracted from NR were composed of carotenoids, tocotrienol esters, fatty alcohol esters, tocotrienols, unsaturated fatty acids, fatty alcohols, diglyceride and monoglyceride. The results will be useful for rubber-technologist to identify the origin to make obnoxious color in natural rubber, especially in some applications which are restricted by such the color.

Biosynthesis, isolation, and structural characterization of ε-poly-l-lysine produced by Streptomyces sp. DES20

RSC Advances ◽  
2016 ◽  
Vol 6 (63) ◽  
pp. 58521-58528 ◽  
Author(s):  
Hongliu Gao ◽  
Shi-Zhong Luo
Keyword(s):  
Structural Characterization ◽  
Antimicrobial Activities ◽  
Streptomyces Sp ◽  
Naturally Occurring

ε-Poly-l-lysine (ε-PL) is an unusual, naturally occurring homo-polyamide made of 25–35l-lysines with antimicrobial activities.

Identification and Structural Characterization of Naturally-Occurring Broad-Spectrum Cyclic Antibiotics Isolated from Paenibacillus

2015 ◽  
Vol 26 (10) ◽  
pp. 1768-1779 ◽  
Author(s):  
Ann M. Knolhoff ◽  
Jie Zheng ◽  
Melinda A. McFarland ◽  
Yan Luo ◽  
John H. Callahan ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Broad Spectrum ◽  
Naturally Occurring

High Resolution Replication of Organoclay Surfaces

1982 ◽  
Vol 40 ◽  
pp. 576-577
Author(s):  
W. W. Barker ◽  
W. E. Rigsby ◽  
V. J. Hurst ◽  
W. J. Humphreys
Keyword(s):  
Clay Mineral ◽  
Organic Molecule ◽  
Organic Molecules ◽  
X Ray Diffraction ◽  
Xrd Pattern ◽  
X Ray ◽  
Naturally Occurring ◽  
Silicate Layers ◽  
Mineral Identification

Experimental clay mineral-organic molecule complexes long have been known and some of them have been extensively studied by X-ray diffraction methods. The organic molecules are adsorbed onto the surfaces of the clay minerals, or intercalated between the silicate layers. Natural organo-clays also are widely recognized but generally have not been well characterized. Widely used techniques for clay mineral identification involve treatment of the sample with H2 O2 or other oxidant to destroy any associated organics. This generally simplifies and intensifies the XRD pattern of the clay residue, but helps little with the characterization of the original organoclay. Adequate techniques for the direct observation of synthetic and naturally occurring organoclays are yet to be developed.

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