scholarly journals Willingness of corneal donation and its associated factors among adult patients attending Gondar University Comprehensive and Specialized Hospital

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256102
Author(s):  
Eyerus Gesesse ◽  
Sofonias Addis Fekadu ◽  
Gizachew Tilahun Belete

Introduction Corneal transplantation is the only treatment option for corneal blindness to restore sight. However, there is a disproportionate imbalance between the demand and supply of corneal tissue in Ethiopia. This is because accessing corneal tissue is reliant on people who are willing to donate corneas after death. Objective This study aimed to assess the proportion of willingness to donate cornea and associated factors among adult patients attending at University of Gondar comprehensive and specialized hospital. Method Institutional based cross-sectional study was conducted from July 13 to July 28, 2020, through a face-to-face interview. A total of 451 samples were selected using systematic random sampling. The data were entered into Epidemiological information version 7 and exported to statistical package for social science version 20 for formal analysis. Variables with a P-value of < 0.20 in a bi-variable logistic regression were entered into the multivariable logistic regression and those variables with a p-value of < 0.05 were taken as statistically significant. The strength of association was shown using the odds ratio with a 95% confidence interval. Result A total of 408 adults participated in this study with a response rate of 90% and the proportion of willingness to donate cornea was 179(43.90%). Participants who had a religious belief in Christianity (AOR = 3.23 (95% CI: 1.09–9.57)) and good knowledge about corneal donation (AOR = 5.45(95%CI: 2.69–11.18)) were positively associated with the willingness of corneal donation. On the other side, the age group above 43 years (AOR = 0.31(95% CI: 0.11–0.89) was negatively associated with the willingness of corneal donation. Conclusion The proportion of willingness to donate cornea 43.9% among participants attending Gondar University Comprehensive and Specialized Hospital. Age group greater than 43 years, religion of Christianity and good knowledge were associated with the willingness of corneal donation.

2020 ◽  
Author(s):  
Befikaduwa Zekarias ◽  
Frehiwot Mesfin ◽  
Bezatu Mengiste ◽  
Adane Tesfaye ◽  
Lemma Getacher

Abstract Background: Iodine deficiency disorder is a major public health problem in Ethiopia that is more common in women of reproductive age. However, it is not well addressed and there is a lack of information on its prevalence and associated factors in women of reproductive age group. Therefore, the objective of this study was to assess goiter prevalence and associated factors among women of reproductive age in the Demba Goffa Woreda, Gamo Goffa Zone, and Southwest Ethiopia.Methods: A community-based cross-sectional study was used among 584 randomly selected women in the reproductive age group from February 05 to April 20, 2016. A simple random sampling technique was used to select the study Kebeles, and a systematic random sampling technique was used to select the study samples. Data were collected through a pretested questionnaire, and the goiter examination was done clinically for each participant. The collected data were coded and entered into a computer for statistical analysis using Epi-data version 3.2 and analyzed using SPSS version 20. Variables with a P-value ≤ 0.25 in bivariate logistic regression analysis were entered into multivariate logistic regression analysis, and finally, variables with a P-value < 0.05 in multivariate logistic regression were considered significantly associated with the dependent variable.Results: The total goiter rate was 43%, 95% CI = (39.2-46.9). Cassava consumption (AOR: 2.02, 95% CI: (1.03-4)), salt wash before use (AOR: 3.14, 95% CI: (1.1-11.3)), salt use after > 2 months of purchase (AOR: 11, 95% CI; (5-26)), family history of goiter (AOR: 4.6, 95% CI: (1.4-15.8)), and poor knowledge of iodized salt (AOR: 2.7, 95% CI (1.4-5.5)) were significant factors associated with goiter.Conclusion: Iodine deficiency was found to be severe in women of reproductive age in the study area. This showed that women of reproductive age, especially during pregnancy, are exposed to iodine deficiency and its adverse effects at delivery. Thus, they need urgent supplementation with iodine, improved access to foods rich in iodine and intake of iodized salt. Additionally, health education should focus on the importance of iodized salt, the proper method of use and the prevention of iodine deficiency, which are highly recommended to minimize the problem.


PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249736
Author(s):  
Anteneh Ayelign Kibret ◽  
Mohammed Oumer ◽  
Abebe Muche Moges

Introduction Hemorrhoidal disease is a very common benign anorectal disease. It affects millions of people around the world, and represent a major medical and socioeconomic problem. However, studies that determine the magnitude and risk factors are limited. Therefore, the aim this study is to assess the prevalence and associated factors of hemorrhoid among adult patients visiting the surgical outpatient department at the University of Gondar Comprehensive Specialized Hospital (UoGCSH) Northwest Ethiopia. Methods An institution-based cross-sectional study was conducted from February to May 2020. A systematic random sampling technique was used to select a total of 403 participants. The data were collected then entered using EPI DATA version 3.1 and exported to the STATA 14 for analysis. Bivariable and multivariable logistic regression analysis were performed. Adjusted odds ratio (AOR) with 95% confidence interval was used as a measure of association. Variables having P-value < 0.05 from the multivariable analysis were considered to have a significant association with the outcome. Result Out of the 403 study participants, 13.1% (95%CI; 10.1, 16.8) had hemorrhoids. Constipation (AOR = 4.32, 95% CI; 2.20, 8.48) and BMI ≥25kg/m2 (AOR = 2.6, 95% CI; 1.08, 6.23) had a statistically significant association with hemorrhoid. Conclusion The overall prevalence of hemorrhoid was high and its prevalence was higher in male subjects. Constipation and being overweight were found to increase the odds of having hemorrhoids. Screening for early identification and intervention of hemorrhoids, especially for risk groups is better to be practiced by health professionals.


PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256195
Author(s):  
Nigist Alemayehu Woldekidan ◽  
Ammas Siraj Mohammed ◽  
Amsalu Degu ◽  
Yohannes Tadiwos

Background Psychiatric patients are at increased risk of being overweight or obese, and subsequently develop metabolic syndrome. Nevertheless, data regarding associated factors for weight gain are limited and inconsistent. Objective The present study aimed to determine the risk of metabolic syndrome and its associated factors among psychiatric patients. Method A cross-sectional quantitative study was conducted among all psychiatric patients at the Psychiatric Unit of the University of Gondar Comprehensive Specialized Hospital from March 1- April 1, 2018. All eligible psychiatric patients were interviewed about their socio-demographic status,and clinical characteristics and useful parameters for the study were recorded from the medical records of the patients and by measuring waist to height ratio. Descriptive statistics were used to summarize baseline information.Binary logistic regression was used to determine the associated factors and P-value <0.05 and confidence interval (CI) of 95% were used as cut off points for determining statistical significance. Result From 300 patients included in the study, 168(56%) patients were females,and around 50.3% of the study participants had low literacy levels. As per waist to a height ratio scale, 58% (174) of the patients had a risk of metabolic syndrome. The Binary logistic regression analysis indicated that sex (p-<0.0001), occupation (p -0.032), marital status (p-0.006), and distance from the hospital (p<0.0001) were statistically significant determinants of metabolic syndrome risk in the psychiatric patient in our setting. Conclusion The majority of the psychiatric patients in the study setting had a risk of metabolic syndrome. Sex, marital status, employment status, and distance to the hospital were significantly associated with metabolic syndrome. Routine physical and laboratory investigations to detect metabolic syndrome are indispensable in psychiatric patients to prevent cardiovascular complications.


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Befikaduwa Zekarias ◽  
Frehiwot Mesfin ◽  
Bezatu Mengiste ◽  
Adane Tesfaye ◽  
Lemma Getacher

Background. Iodine deficiency disorder is a major public health problem in Ethiopia that is more common in women of reproductive age. However, it is not well addressed and there is a lack of information on its prevalence and associated factors in women of reproductive age group. Therefore, the objective of this study was to assess goiter prevalence and associated factors among women of reproductive age in the Demba Gofa woreda, Gamo Gofa Zone, Southwest Ethiopia. Methods. A community-based cross-sectional study was used among 584 randomly selected women in the reproductive age group from February 05 to April 20, 2016. A simple random sampling technique was used to select the study kebeles, and a systematic random sampling technique was used to select the study samples. Data were collected through a pretested questionnaire, and the goiter examination was done clinically for each participant. The collected data were coded and entered into a computer for statistical analysis using EpiData version 3.2 and analyzed using SPSS version 20. Variables with a P value ≤0.25 in bivariate logistic regression analysis were entered into multivariate logistic regression analysis, and finally, variables with a P value <0.05 in multivariate logistic regression were considered significantly associated with the dependent variable. Results. The total goiter rate was 43%, 95% CI = 39.2–46.9. Cassava consumption (AOR: 2.02, 95% CI: 1.03–4), salt wash before use (AOR: 3.14, 95% CI: 1.1–11.3), salt use after >2 months of purchase (AOR: 11, 95% CI: 5–26), family history of goiter (AOR: 4.6, 95% CI: 1.4–15.8), and poor knowledge of iodized salt (AOR: 2.7, 95% CI: 1.4–5.5) were significant factors associated with goiter. Conclusion. Iodine deficiency was found to be severe in women of reproductive age in the study area. This showed that women of reproductive age, especially during pregnancy, are exposed to iodine deficiency and its adverse effects at delivery. Thus, they need urgent supplementation with iodine, improved access to foods rich in iodine, and intake of iodized salt. Additionally, health education should focus on the importance of iodized salt, the proper method of use, and the prevention of iodine deficiency, which are highly recommended to minimize the problem.


Author(s):  
Munazza Aziz ◽  
Shahbaz Ahmed ◽  
Fazal-ur-Rehman Qazi ◽  
Farah Naz ◽  
Marina Shah ◽  
...  

Abstract Objective: To determine the effect of pre-cooling agent on the intensity of pricking pain at the intraoral injection site in adult patients. Method: An in-vivo interventional study, using split-mouth technique was conducted in the Department of Operative Dentistry, Dr. Ishrat-ul-Ebad Khan Institute of Oral Health Sciences, DUHS, Karachi, between September 2018 to August 2019. Total 152 adult patients meeting the inclusion criteria were selected, and consent form was signed to investigate the pricking pain perception during needle administration. Topical anesthesia (benzocaine gel) was applied on left side (control) for 1 min whereas on the experimental (right) side the refrigerated cartridge was placed for 2 minutes. Infiltration anesthesia was then administered on both sides respectively. Patient’s pain perception ratings were measured through Visual analog scale (VAS). After profound anesthesia was achieved, restorative treatment was performed under rubber dam isolation. Statistical analysis was done using SPSS Version 24. Results: The effect of pre-cooling agent i.e. refrigerated cartridge, was statistically significant (P-value <0.05) on the intensity of pricking pain at the intraoral injection site among the age group of 41 to 50 years and female participants of 21to 30 years whereas the effect of pre-cooling agent was found statistically insignificant among the male participants of the age group of 21 to 30 years and irrespective of gender within 31 to 40 years of age. Conclusion: Pre-cooling agent was found effective in decreasing pricking pain sensed by the patients. Precooling agent can be used without topical anesthesia before administering infiltration because cryoanesthesia Continuous...


2020 ◽  
Vol 3 (1) ◽  
pp. 49-58
Author(s):  
Ngozi Adefala ◽  
Kolawole Sodeinde ◽  
Abiodun Osinaike ◽  
Fikayo Bamidele ◽  
Adebola Omotosho

Objective: This study aimed to assess the knowledge, attitude and practice towards condom utilization and other associated factors among people living with HIV/AIDS enrolled in the Virology clinic in Babcock University Teaching Hospital (BUTH) Ilishan, Ogun state, Nigeria. Methods: This cross-sectional study was conducted among 285 ART users selected using a systematic random sampling method. The minimum sample size was estimated using the formula z2pq/d2 and a 24% prevalence extracted from a previous similar study. Data were elicited using a structured interviewer-administered questionnaire, analyzed using SPSS version 20, and presented as tables. The Chi-square test was used to assess associations between categorical variables. The level of significance was set at the 95% confidence interval with a p-value of 0.05. Results: From the total respondents, 180(63.2%) were females, 93.7% had good knowledge, 141(49.5%) believed ARV prevents transmission of HIV and 144 (50.5%) strongly agreed that condom reduces sexual pleasure. Majority 254 (89.1%) were currently using condoms, 131 (46.0%) used a condom consistently, while 108 (37.9%) frequently use a condom during sexual intercourse. The Use of condoms had statistically significant associations with occupation (p<0.001), married at pre-diagnosis of HIV (p<0.001), married at post-diagnosis of HIV (p<0.001) and education (p= 0.015). Conclusion: The majority of the respondents had good knowledge and were using condoms. Discussions on safe sex and improved positive attitudes towards condom-use should, however, be encouraged further.


2019 ◽  
Author(s):  
Jemal H Ali

Abstract Background: Human immuno-deficiency virus is a virus that causes Acquired Immuno- Deficiency Syndrome. The key goal of ART is to achieve and maintain durable viral suppression. Thus, the most important use of the viral load is to monitor the effectiveness of therapy after initiation of ART. The main objective of the study was to determine the time for virological suppression and its associated factors among people living with HIV taking antiretroviral treatments in East shewa zone, Oromiya, Ethiopia. Methods: The study was conducted in East Shewa zone, Oromiya, Ethiopia from August 2017 to January 2018. Patients diagnosed with human immunodeficiency virus presenting to the study health centers between October 3, 2011 and March 1, 2013 were included in the study given the following criteria: age 18 years or greater, eligible to start ART. All patients with baseline viral load measurement were included in the study. Interaction between explanatory variables with the response variable was analyzed by using cross tab features of SPSS, IBM Inc. Significance group comparison was done by Kaplan Meier log rank test. Cox proportional hazard model was used to select significant factors to the variability between groups. Data was collected by using structured questionnaires and interview. A total of ETB 81,120.00 was utilized to carry out the study. Result: plasma viral load was suppressed below detection level in 72% of individuals taking different regimen of ART. The median HIV-1 plasma viral load in the cohort was log 5.3111 copies/ml. Survival curve difference were observed in category of marital status (p-value 0.023) and baseline CD4 values (p-value 0.023) whereas no significant difference were observed in Educational status (p-value 0.404), MUAC (p- value 0.407) BMI(p-value 0.335) and BTB(p-value 0.257). Estimated median time to PVL suppression was 181days (CI: 140.5-221.4) with the age group of 30-39years having minimum time to achieve suppression with 92 days (CI: 60.1-123.8) and the maximum time required to reach the level was age group between 50-59 years. Conclusion: Estimated time to achieve PVL after taking ART was found to be 181 days. Factors affecting time to suppression level was marital status and baseline CD4.


2020 ◽  
Vol 6 (1) ◽  
pp. 32-37
Author(s):  
Chhimi Wangmo ◽  
Nor Tshering Lepcha

Introduction: The aim of this hospital-based study was to assess the prevalence and associated factors of pterygium among adult patients visiting the Ophthalmology Outpatient Department (OPD) in the Jigme Dorji Wangchuck National Referral Hospital (JDWNRH), Thimphu. Methods: A cross sectional study was carried out in the ophthalmology OPD in the national referral hospital, Thimphu from 1st January, 2018 to 31st December, 2018, during which 1599 adult patients were selected through systematic random sampling. Results: The prevalence of pterygium was 12.8% (95% CI: 11.2 -14.5). Among 271 eyes with pterygium, the distribution of grade 1, grade 2 and grade 3 pterygium was 34.7%, 56.1% and 9.2% respectively. Pterygium wasmost common in the age group of 36-55 years. The significant factors associated with pterygium were age group, occupation and usage of sunglasses. Individuals who were 36-55 years (adjusted OR 2.70, 95% CI 1.82-4.0) and >55 years (adjusted OR 2.17, 95% CI 1.34-3.50) had significantly higher risk than 18-35 years (p< 0.002), and not using sunglasses (adjusted OR 1.97, 95% CI1.17-3.33, p = 0.007) significantly increased the risk of pterygium. Indoor occupation, particularly being a student was protective against pterygium (OR 0.08, 95% CI 10.02-0.33, p< 0.001). Only 14.1% used sunglasses and among them, 27.6% were aware that sunglasses can protect from ultraviolet radiation. Conclusion: This study found a high prevalence of pterygium among adults aged 18 years and above. Those aged 36-55 years and an occupation involving outdoor activities were affected more. Encouraging usage of sunglasses may reduce pterygium


2019 ◽  
Author(s):  
Kibeb seid ◽  
Terefe Derso ◽  
atsede mazengia shiferaw

Abstract Introduction Anthrax is an infectious bacterial disease transmitted from infected animal to human by direct or indirectcontact with their products like hides or wool. The most efficient ways of anthrax infection preventions are vaccination of livestock, surveillance, and proper disposal of livestock carcasses in domestic herd.Recently, anthrax infection in humans has been reported from several districts spreadcountrywide and becomes a major public health problem of animals-humans in Amhara region (the study area).Objective This study aimed at determining knowledge of anthrax infection prevention and its associated factors among livestock owners in Sekotazuria district.Method Community based cross-sectional quantitative study was conducted from April to May, 2018, at Sekotazuria district, Northeast Ethiopia. A total of 844 live-stoke owners were selected from Sekotazuria district using simple random sampling technique. Data were collected using a structured self-administered questionnaire and data were cleaned, coded, and entered into Epi-info version 3.5.3, and transferred into SPSS version 20 for further statistical analysis. A p-value of less than 0.05 at multiple logistic regression analysis was considered statistically significant.Results The study revealed that good knowledge of anthrax prevention among livestock owners was 55.8% (95%CI: 54.2, 57.4%). According to multivariable logistic regression analysis, secondary and above educational level[AOR=2.97, 95% CI: 1.07, 8.20], age range of 42 – 80 [AOR=1.47, 95% CI: 1.04, 2.07], and health education about anthrax [AOR=4.25, 95% CI: 2.51, 7.17]were found significantly associated with good knowledge of anthrax infection prevention.Conclusion More than half of livestock owners at SekotaZuria District had good knowledge towards anthrax infection prevention, education level in secondary and above,respondents age category 42-80 years, and health education about anthrax were factors associated with knowledge of anthrax infection prevention. Therefore, health education about anthrax shall be strengthening.


2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Asmare Talie ◽  
Mekuanint Taddele ◽  
Mulunesh Alemayehu

Background. Low birth weight is defined as a live born infant weighs less than 2 500 g regardless of gestational age. Globally, the prevalence of low birth weight ranges from 3% to 15%. Birth weight plays an important role in infant mortality, morbidity, development, and future health. The prevalence of low birth weight in Ethiopia was estimated to be 14% which is one of the highest percentages in the world. So, the aim of this study is to assess magnitude and associated factors of low birth weight among newborns delivered at Dangla Primary Hospital, Amhara Region, Ethiopia. Methods. An institution-based cross-sectional study was conducted at Dangla Primary Hospital from September 27 to June 10, 2017. Systematic random sampling technique was used to select the 232 study participants. A structured and pretested questionnaire was used to collect data. Data quality was assured by pretesting, training, and frequent supervision. Descriptive statistics were performed for the descriptive part of the study. Binary and multiple logistic regression analyses were conducted to identify independent predictors of low birth weight. Those variables and p-value < 0.25 were included in the multivariable logistic regression for controlling the possible effect of confounders. Finally, variables which had significant association were identified on the basis of AOR, with 95%CI and with P-value <0.05. Results. Magnitude of low birth weight was 10.3 %. Previous history of low birth weight [AOR = 3.2, 95% CI: (1.13-9.9)], additional food intake during the last pregnancy [AOR = 5.0, 95% CI: (1.2-16.2)], and preterm delivery [AOR = 2.1, 95% CI: (3.1-19.2)] were independent predictors of low birth weight. Conclusion. Magnitude of low birth weight in Dangla Primary Hospital was high. So, strengthening counseling systems for women through quality antenatal care on advantage of additional food intake and previous bad obstetric outcome is necessary to alleviate the delivery of low birth weight neonates in the study area.


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