scholarly journals COVID-19 vaccine hesitancy and refusal and associated factors in an adult population in Saskatchewan, Canada: Evidence from predictive modelling

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0259513
Author(s):  
Nazeem Muhajarine ◽  
Daniel A. Adeyinka ◽  
Jessica McCutcheon ◽  
Kathryn L. Green ◽  
Miles Fahlman ◽  
...  

Background A high population level of vaccination is required to control the COVID-19 pandemic, but not all Canadians are convinced of the value and safety of vaccination. Understanding more about these individuals can aid in developing strategies to increase their acceptance of a COVID-19 vaccine. The objectives of this study were to describe COVID-19 vaccine acceptance, hesitancy and refusal rates and associated factors in Saskatchewan, Canada. Methods This is a cross-sequential study that consisted of pooled responses from weighted samples of 9,252 Saskatchewan adults (≥18 years) across nine rounds of data collection between May 4, 2020 and April 3, 2021. The outcome variable was vaccine intention: vaccine acceptance, hesitancy, and refusal. The independent variables were layered into socio-demographic factors, risk of exposure to coronavirus, mitigating behaviours, and perceptions of COVID-19. Data were analyzed using multinomial logistic regression and a classification and regression tree. Results Seventy-six percent of the respondents indicated that they had been or were willing to be vaccinated, 13% had not yet decided, and the remaining 11% said they would not be vaccinated. Factors that increased the likelihood of vaccine refusal and hesitancy were lower education level, financial instability, Indigenous status, and not being concerned about spreading the coronavirus. Perceiving COVID-19 to be more of a threat to one’s community and believing that one had a higher risk of illness or death from COVID-19 decreased the likelihood of both vaccine refusal and hesitancy. Women and newcomers to Canada were more likely to be unsure about getting vaccinated. Respondents who did not plan to be vaccinated were less likely to wear face masks and practice physical distancing. Conclusion While many Canadians have voluntarily and eagerly become vaccinated already, reaching sufficient coverage of the population is likely to require targeted efforts to convince those who are resistant or unsure. Identifying and overcoming any barriers to vaccination that exist within the socio-demographic groups we found were least likely to be vaccinated is a crucial component.

2021 ◽  
Author(s):  
Nazeem Muhajarine ◽  
Daniel A Adeyinka ◽  
Jessica McCutcheon ◽  
Kathryn L Green ◽  
Miles Fahlman ◽  
...  

Background. A high population level of vaccination is required to control the COVID-19 pandemic, but not all Canadians are ready to get a vaccine. The objectives of this study were to describe COVID-19 vaccine acceptance, hesitancy and refusal rates and associated factors in Saskatchewan, Canada. Methods. This study consisted of a weighted sample of 9,252 survey responses from 7,265 Saskatchewan adults between May 4, 2020 and April 3, 2021. The outcome variable was vaccine intention: vaccine acceptance, hesitancy, and refusal. The independent variables were socio-demographic factors, risk of exposure to coronavirus, mitigating behaviours, and perceptions of COVID-19. Results. Seventy-six percent of the respondents indicated that they had been or were willing to be vaccinated, 13% not decided, and the remaining 11% said would not be vaccinated. Factors that increased the likelihood of vaccine refusal and hesitancy were lower education level, financial instability, Indigenous status, and not being concerned about spreading the coronavirus. Conclusion. Reaching sufficient coverage of the population is likely to require targeted efforts to convince those who are resistant or unsure.


Vaccines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 798
Author(s):  
Sami H. Alzahrani ◽  
Mukhtiar Baig ◽  
Mohammed W. Alrabia ◽  
Mohammed R. Algethami ◽  
Meshari M. Alhamdan ◽  
...  

Vaccine uptake could influence vaccination efforts to control the widespread COVID-19 pandemic; however, little is known about vaccine acceptance in Saudi Arabia. The present study aimed to assess the Saudi public’s intent to get vaccinated against COVID-19 and explore the associated demographic determinants of their intentions as well as the reasons for vaccine hesitancy. A cross-sectional, web-based survey was distributed to public individuals in Saudi Arabia between 25 December 2020 and 15 February 2021. Participants were asked if they were willing to get vaccinated, and the responses, along with demographic data were entered into a multinomial logistic regression model to assess the relative risk ratio (RRR) for responding “no” or “unsure” versus “yes”. Among 3048 participants (60.1% female, 89.5% Saudi), 52.9% intend to get vaccinated, 26.8% were unsure, and 20.3% refused vaccination. Vaccine hesitancy was significantly higher among females (RRR = 2.70, p < 0.0001) and those who had not been recently vaccinated for influenza (RRR = 2.63, p < 0.0001). The likelihood was lower among Saudis (RRR = 0.49, p < 0.0001), those with less than a secondary education (RRR = 0.16, p < 0.0001), perceived risks of COVID-19, and residents of the southern region (RRR = 0.46, p < 0.0001). The most often cited reasons for hesitancy were short clinical testing periods and concerns about adverse events or effectiveness. Vaccine hesitancy is mediated by many demographic factors and personal beliefs. To address vaccine-related concerns and amend deeply rooted health beliefs, communication should provide transparent information.


2021 ◽  
pp. 12-14
Author(s):  
Monica Kalyanaraman ◽  
Parameswari Srijayanth ◽  
Srinivas Govindarajulu

Background: Coronavirus outbreak was a highly unpredicted global burden that caused millions of deaths across the world. Vaccination against the infection declines the morbidity and mortality rates. This study objective aims to determine the reasons for the vaccine acceptance. Methods: A cross sectional study was conducted through an online survey among the people living in chennai, Tamilnadu. An E-survey Google forms are circulated through the social platforms and email. Excluding the non-response all the data gained was descriptively analyzed. Results: Out of total (n =376 ≥ 18 years) participants majority of them showed High acceptance and got already vaccinated whereas some revealed the fear of vaccine safety and risk effects. Vaccine hesitancy is seen in terms of lack of trust and proper awareness, myths about adverse effects. In addition our ndings positively convey the knowledge of effective preventive measures for infection and proper following of government guidelines. Conclusion: The study outcomes even though shows willingness of the people in receiving the vaccine at some point still a notable interruption is seen. Prioritization should be given to those critical areas to inuence the public perception about vaccine benets because now vaccination is the only essential measure to suppress the healthcare pressure which halts the covid 19 infection.


2021 ◽  
Author(s):  
Mohamed amine Kerdoun ◽  
Hamza Abdellah Henni ◽  
Assia Yamoun ◽  
Amine Rahmani ◽  
Rym Messaouda Kerdoun ◽  
...  

Vaccine hesitancy is a limiting factor in global efforts to contain the current pandemic, wreaking havoc on public health. As today's students are tomorrow's doctors, it is critical to understand their attitudes toward the COVID-19 vaccine. To our knowledge, this study was the first national one to look into the attitudes of Algerian medical students toward the SARS-CoV-2 vaccine using an electronic convenience survey. 383 medical students from five Algerian universities were included, with a mean age of 21.02. 85.37% (n=327) of respondents had not taken the COVID-19 vaccine yet and were divided into three groups; the vaccine acceptance group (n=175, 53.51%), the vaccine-hesitant group (n=75, 22.93%), and the vaccine refusal group (n=77, 23.54%). Gender, age, education level, university, and previous experience with COVID-19 were not significant predictors for vaccine acceptance. The confirmed barriers to the COVID-19 vaccine concern available information, effectiveness, safety, and adverse effects. This work highlights the need for an educational strategy about the safety and effectiveness of the COVID-19 vaccine. Medical students should be educated about the benefits of vaccination for themselves and their families and friends. The Vaccine acceptant students' influence should not be neglected with a possible ambassador role to hesitant and resistant students.


2020 ◽  
Author(s):  
Usue Elizondo-Alzola ◽  
Mireia G. Carrasco ◽  
Laia Pinós ◽  
Camila Andrea Picchio ◽  
Cristina Rius ◽  
...  

Abstract Background. Immunization rates of immuno-preventable diseases have declined in recent decades due to vaccine hesitancy. Primary care nurses play an essential role in promoting and maintaining vaccination coverage but may have doubts about or question the need to vaccinate. This study describes the prevalence of vaccine hesitancy and the associated factors among pediatric primary care nurses in Barcelona (Spain).Methods. Cross-sectional descriptive study. We invited the pediatric nurses (N = 165) working at all the Barcelona public primary health services (N = 41) to participate. They answered a questionnaire with sociodemographic and behavioral variables: severity and probability of contracting the diseases in the vaccination schedule; safety and protection of each vaccine; and beliefs, social norms, and knowledge about vaccines. Outcome variable was vaccine hesitancy, dichotomized into no hesitant (nurses who would vaccinate their own offspring), and hesitant (including those who would not vaccinate them, those who had doubts and those who would delay the administration of one or more vaccines).We performed bivariate analysis and adjusted logistic regression models.Results. 83% of pediatric nurses (N = 137) agreed to participate. A 32.1% of them reported vaccine hesitancy, especially about the HPV (21.9%) and varicella (17.5%) vaccines. In the multivariate analysis, hesitancy was associated with low perception of the severity of whooping cough [aOR: 3.88; (95%CI):1.32–11.4], low perception of safety of the HPV vaccine [aOR:8.5;(95%CI):1.24–57.8], the belief that vaccines are administered too early [aOR:6.09;(95%CI):1.98–18.8], and not having children [aOR:4.05;(95%CI):1.22–13.3].Conclusions. Although most pediatric nurses would vaccinate their own children, almost one third display some kind of vaccine hesitancy, mainly related with doubts about HPV and varicella vaccines, as well as some misconceptions. These factors should be addressed to enhance their fundamental role in promoting vaccination among families.


2021 ◽  
Vol 12 ◽  
Author(s):  
Xiao Qiu ◽  
Heather Bailey ◽  
Claire Thorne

Vaccination during pregnancy is a safe and effective intervention to protect women from potentially severe consequences of influenza and reduce risk of influenza and pertussis in their infants. However, coverage remains variable. In this mini-review we update findings from a 2015 systematic review to describe results from recent studies in high income countries on the uptake of influenza and pertussis vaccination in pregnancy, reasons for vaccine hesitancy and barriers to increasing uptake, from maternal and healthcare provider (HCP) perspectives. Studies reported highly variable uptake (from 0% to 78%). A main facilitator for uptake among pregnant women was receiving a recommendation from their HCP. However, studies showed that HCP awareness of guidelines did not consistently translate into them recommending vaccines to pregnant women. Safety concerns are a well-established barrier to uptake/coverage of maternal immunization; 7%-52% of unvaccinated women gave safety concerns as a reason but these were also present in vaccinated women. Knowledge/awareness gaps among pregnant women and lack of confidence among HCPs to discuss vaccination were both important barriers. Several studies indicated that midwives were more likely to express safety concerns than other HCPs, and less likely to recommend vaccination to pregnant women. Women who perceived the risk of infection to be low were less likely to accept vaccination in several studies, along with women with prior vaccine refusal. Findings highlight the importance of further research to explore context-specific barriers to vaccination in pregnancy, which may include lack of vaccine confidence among pregnant woman and HCPs, and policy and structural factors.


Author(s):  
Farrukh Ansar ◽  
Hira Naveed ◽  
Mudasir Khan ◽  
Almas Khattak

COVID-19 pandemic has caused global healthcare and economic crises and mass vaccination to acquire herd immunity seem to be the only solution. Present study aimed to evaluate the intent of Pakistani population towards vaccination and to uncover the barriers associated with vaccine reluctance. This cross-sectional study included responses of 855 Pakistani residents. Respondents’ knowledge of COVID-19 infection, intent of vaccination and barriers towards vaccine refusal were evaluated. Participants were categorized on the basis of knowledge score, risk of disease and other demographic characteristics. Descriptive statistics were used for calculating frequencies and percentages, means and Chi-square test was utilized for cross-tabulation. A multinomial logistic regression model was executed to identify the predictors of vaccination intention. Significance level was set at the p-value of ? 0.05. Prevalence of vaccine refusal was 40%. COVID-19 vaccine is not Halal, negative propaganda on social media against the vaccine, discouraging advice from social circle and clerics, concerns regarding efficacy, fear of immediate and late adverse reactions were the major barriers identified towards vaccine hesitancy. Around one-third of the study population did not consider COVID-19 as a serious disease and associate it with conspiracy theory. The mean score of participants towards COVID-19 knowledge was 5.5±1.6 (range: 0-9). Having a college degree, living in an urban area, working in a healthcare field and being in a higher risk category increases the chances of vaccine acceptability.


2021 ◽  
Author(s):  
Noura Salibi ◽  
Sawsan Abdulrahim ◽  
Maria El Haddad ◽  
Stephanie Bassil ◽  
Zeina El Khoury ◽  
...  

AbstractThis study assesses COVID-19 vaccine intentions among a sample of Syrian refugees (≥50 years) beneficiaries of a humanitarian organization in Lebanon, and explores factors associated with vaccine refusal. The findings are part of an ongoing rotating 4-wave panel study. The sample was limited to participants from the first panel who completed a phone interview between January-February, 2021. Out 1,037 beneficiaries, almost a third (29%) reported no intention to vaccinate. Reasons for refusal were: newness of the vaccine (35%); preference to maintain precaution measures (21%); belief that COVID-19 vaccine is not essential (21%); and other reasons (23%). COVID-19 vaccine refusal was significantly associated with perceptions regarding vaccine safety (OR: 5.97; 95%CI: 4.03-8.84) and effectiveness (OR: 6.80; 95%CI:4.44-10.42) but did not differ by age, presence of chronic conditions, self-reported adherence to COVID-19 measures, and perceptions of susceptibility to and severity of COVID-19. Addressing vaccine hesitancy among Syrian refugees in Lebanon necessitates disseminating accurate, accessible, and culturally appropriate information about vaccine safety and effectiveness.


2021 ◽  
Vol 6 (5) ◽  

Background: Vaccination is currently considered the major hope to slow down the spread of the current coronavirus disease 2019 (COVID-19) pandemic. Currently, the biggest obstacle against mass vaccination is that people are reluctant to take the vaccine. Objective: The aim of this study is to assess the acceptance and hesitancy towards the COVID-19 vaccine among the general population in Jordan. In addition, the study explores the possible causes of vaccine refusal and the possible associated factors. Methods: The study was conducted by using an online survey distributed in March 2021. It is composed of items that assess the respondent characteristics and their acceptance to the vaccine. Results: A total of 3728 respondents completed the survey. The majority of respondents 60.5% (n = 2255) didn’t register to the platform to take the vaccine, most of them (54.77% were not convinced with the effectiveness of the vaccine). People who work in the health care sector and people with chronic diseases were found to be more likely to receive the vaccine, whereas previously COVID-19 infected and possibly exposed patients both showed hesitancy to sign up for the vaccine. Conclusion: The effectiveness and safety of different vaccines should be widely available to the general population, and be scientifically explained in a simple trustful way. In addition, more awareness programs probably need to target the hesitant groups, including the previously infected patients.


Vaccines ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 1389
Author(s):  
Megumi Hara ◽  
Motoki Ishibashi ◽  
Atsushi Nakane ◽  
Takashi Nakano ◽  
Yoshio Hirota

Little is known about the differences in coronavirus disease (COVID-19) vaccine acceptance and hesitancy between the general population and healthcare workers in Japan. To compare these differences, a nationwide web-based cross-sectional survey was conducted on 19 January 2021, shortly before the initiation of COVID-19 vaccinations in Japan. A total of 6180 men and women aged 20–69 years and 1030 healthcare workers aged 20–69 years were enrolled. Data on COVID-19 vaccine acceptance, basic characteristics, including socioeconomic factors, and confidence in immunization in general were collected. COVID-19 vaccine acceptance was also evaluated under hypothetical vaccine effectiveness and adverse event frequencies. Factors associated with vaccine hesitancy were examined using multinomial logistic regression analysis. The COVID-19 vaccine acceptance rate was 48.6% among the general population and was lower among nurses (45.5%) and medical clerks (40.7%). Women and young adults had significantly higher COVID-19 vaccine hesitancy odds ratios, and current smokers had significantly lower odds ratios. The frequency of adverse events was a COVID-19 vaccine hesitancy factor. Even if these factors were adjusted, COVID-19 vaccine hesitancy among nurses was 1.4 times higher than that among the general population. Thus, interventions to improve health literacy and vaccine hesitancy among the general population and healthcare workers, especially nurses, are needed.


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