scholarly journals Determining the timing of pubertal onset via a multicohort analysis of growth

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0260137
Author(s):  
Essi Syrjälä ◽  
Harri Niinikoski ◽  
Helena E. Virtanen ◽  
Jorma Ilonen ◽  
Mikael Knip ◽  
...  

Objective Growth-based determination of pubertal onset timing would be cheap and practical. We aimed to determine this timing based on pubertal growth markers. Secondary aims were to estimate the differences in growth between cohorts and identify the role of overweight in onset timing. Design This multicohort study includes data from three Finnish cohorts—the Type 1 Diabetes Prediction and Prevention (DIPP, N = 2,825) Study, the Special Turku Coronary Risk Factor Intervention Project (STRIP, N = 711), and the Boy cohort (N = 66). Children were monitored for growth and Tanner staging (except in DIPP). Methods The growth data were analyzed using a Super-Imposition by Translation And Rotation growth curve model, and pubertal onset analyses were run using a time-to-pubertal onset model. Results The time-to-pubertal onset model used age at peak height velocity (aPHV), peak height velocity (PHV), and overweight status as covariates, with interaction between aPHV and overweight status for girls, and succeeded in determining the onset timing. Cross-validation showed a good agreement (71.0% for girls, 77.0% for boys) between the observed and predicted onset timings. Children in STRIP were taller overall (girls: 1.7 [95% CI: 0.9, 2.5] cm, boys: 1.0 [0.3, 2.2] cm) and had higher PHV values (girls: 0.13 [0.02, 0.25] cm/year, boys: 0.35 [0.21, 0.49] cm/year) than those in DIPP. Boys in the Boy cohort were taller (2.3 [0.3, 4.2] cm) compared with DIPP. Overweight girls showed pubertal onset at 1.0 [0.7, 1.4] year earlier compared with other girls. In boys, there was no such difference. Conclusions The novel modeling approach provides an opportunity to evaluate the Tanner breast/genital stage–based pubertal onset timing in cohort studies including longitudinal data on growth but lacking pubertal follow-up.

2020 ◽  
Vol 52 (7S) ◽  
pp. 583-584
Author(s):  
Jodi N. Dowthwaite ◽  
Matthew J. Pelowski ◽  
Jennifer E. Minassian ◽  
Tamara A. Scerpella

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1320
Author(s):  
Humberto Peña-Jorquera ◽  
Valentina Campos-Núñez ◽  
Kabir P. Sadarangani ◽  
Gerson Ferrari ◽  
Carlos Jorquera-Aguilera ◽  
...  

This study aimed to determine whether pupils who have breakfast just before a cognitive demand, do not regularly skip breakfast, and consume a high-quality breakfast present higher cognitive performance than those who do not; furthermore, to establish differences according to their nutritional status. In this study, 1181 Chilean adolescents aged 10–14 years participated. A global cognitive score was computed through eight tasks, and the body mass index z-score (BMIz) was calculated using a growth reference for school-aged adolescents. The characteristics of breakfast were self-reported. Analyses of covariance were performed to determine differences in cognitive performance according to BMIz groups adjusted to sex, peak height velocity, physical fitness global score, and their schools. A positive association was found in adolescents’ cognitive performance when they had breakfast just before cognitive tasks, did not regularly skip breakfast, presented at least two breakfast quality components, and included dairy products. No significant differences were found between breakfast components, including cereal/bread and fruits/fruit juice. Finally, pupils who were overweight/obese who declared that they skipped breakfast regularly presented a lower cognitive performance than their normal-BMIz peers. These findings suggest that adolescents who have breakfast just prior to a cognitive demand and regularly have a high quality breakfast have better cognitive performance than those who do not. Educative nutritional strategies should be prioritized, especially in “breakfast skippers” adolescents living with overweight/obesity.


2020 ◽  
Vol 33 (12) ◽  
pp. 1589-1595
Author(s):  
Mariana del Pino ◽  
Virginia Fano ◽  
Paula Adamo

AbstractObjectivesIn general population, there are three phases in the human growth curve: infancy, childhood and puberty, with different main factors involved in their regulation and mathematical models to fit them. Achondroplasia children experience a fast decreasing growth during infancy and an “adolescent growth spurt”; however, there are no longitudinal studies that cover the analysis of the whole post-natal growth. Here we analyse the whole growth curve from infancy to adulthood applying the JPA-2 mathematical model.MethodsTwenty-seven patients, 17 girls and 10 boys with achondroplasia, who reached adult size, were included. Height growth data was collected from birth until adulthood. Individual growth curves were estimated by fitting the JPA-2 model to each individual’s height for age data.ResultsHeight growth velocity curves show that after a period of fast decreasing growth velocity since birth, with a mean of 9.7 cm/year at 1 year old, the growth velocity is stable in late preschool years, with a mean of 4.2 cm/year. In boys, age and peak height velocity in puberty were 13.75 years and 5.08 cm/year and reach a mean adult height of 130.52 cm. In girls, the age and peak height velocity in puberty were 11.1 years and 4.32 cm/year and reach a mean adult height of 119.2 cm.ConclusionsThe study of individual growth curves in achondroplasia children by the JPA-2 model shows the three periods, infancy, childhood and puberty, with a similar shape but lesser in magnitude than general population.


2017 ◽  
Vol 12 (3) ◽  
pp. 344-350 ◽  
Author(s):  
Ashley J Cripps ◽  
Christopher Joyce ◽  
Carl T Woods ◽  
Luke S Hopper

This study compared biological maturation, anthropometric, physical and technical skill measures between talent and non-talent identified junior Australian footballers. Players were recruited from the under 16 Western Australian Football League and classified as talent (state representation; n = 25, 15.7 ± 0.3 y) or non-talent identified (non-state representation; n = 25, 15.6 ± 0.4 y). Players completed a battery of anthropometric, physical and technical skill assessments. Maturity was estimated using years from peak height velocity calculations. Binary logistic regression was used to identify the variables demonstrating the strongest association with the main effect of ‘status’. A receiver operating characteristic curve was used to assess the level of discrimination provided by the strongest model. Talent identified under 16 players were biologically older, had greater stationary and dynamic leaps and superior handball skill when compared to their non-talent identified counterparts. The strongest model of status included standing height, non-dominant dynamic vertical jump and handball outcomes (AUC = 83.4%, CI = 72.1%–95.1%). Biological maturation influences anthropometric and physical capacities that are advantageous for performance in Australian football; talent identification methods should factor biological maturation as a confound in the search for junior players who are most likely to succeed in senior competition.


2017 ◽  
Vol 135 (3) ◽  
pp. 253-259 ◽  
Author(s):  
Ricardo Ribeiro Agostinete ◽  
Igor Hideki Ito ◽  
Han Kemper ◽  
Carlos Marcelo Pastre ◽  
Mário Antônio Rodrigues-Júnior ◽  
...  

ABSTRACT CONTEXT AND OBJECTIVE: Peak height velocity (PHV) is an important maturational event during adolescence that affects skeleton size. The objective here was to compare bone variables in adolescents who practiced different types of sports, and to identify whether differences in bone variables attributed to sports practice were dependent on somatic maturation status. DESIGN AND SETTING: Cross-sectional study, São Paulo State University (UNESP). METHODS: The study was composed of 93 adolescents (12 to 16.5 years old), divided into three groups: no-sport group (n = 42), soccer/basketball group (n = 26) and swimming group (n = 25). Bone mineral density and content were measured using dual-energy x-ray absorptiometry and somatic maturation was estimated through using peak height velocity. Data on training load were provided by the coaches. RESULTS: Adolescents whose PHV occurred at an older age presented higher bone mineral density in their upper limbs (P = 0.018). After adjustments for confounders, such as somatic maturation, the swimmers presented lower values for bone mineral density in their lower limbs, spine and whole body. Only the bone mineral density in the upper limbs was similar between the groups. There was a negative relationship between whole-body bone mineral content and the weekly training hours (β: -1563.967; 95% confidence interval, CI: -2916.484 to -211.450). CONCLUSION: The differences in bone variables attributed to sport practice occurred independently of maturation, while high training load in situations of hypogravity seemed to be related to lower bone mass in swimmers.


2019 ◽  
Vol 14 (5) ◽  
pp. 674-680 ◽  
Author(s):  
Olaf Prieske ◽  
Helmi Chaabene ◽  
Christian Puta ◽  
David G. Behm ◽  
Dirk Büsch ◽  
...  

Purpose: To examine the effects of drop height on drop-jump (DJ) performance and on associations between DJ and horizontal-jump/sprint performances in adolescent athletes. Methods: Male (n = 119, 2.5 [0.6] y post-peak-height velocity) and female (n = 120, 2.5 [0.5] y post-peak-height velocity) adolescent handball players (national level) performed DJs in randomized order using 3 drop heights (20, 35, and 50 cm). DJ performance (jump height, reactive strength index [RSI]) was analyzed using the Optojump Next system. In addition, correlations were computed between DJ height and RSI with standing-long-jump and 20-m linear-sprint performances. Results: Statistical analyses revealed medium-size main effects of drop height for DJ height and RSI (P < .001, 0.63 ≤ d ≤ 0.71). Post hoc tests indicated larger DJ heights from 20 to 35 and 35 to 50 cm (P ≤ .031, 0.33 ≤ d ≤ 0.71) and better RSI from 20- to 35-cm drop height (P < .001, d = 0.77). No significant difference was found for RSI between 35- and 50-cm drop height. Irrespective of drop height, associations of DJ height and RSI were small with 5-m-split time (−.27 ≤ r ≤ .05), medium with 10-m-split time (−.44 ≤ r ≤ .14), and medium to large with 20-m sprint time and standing-long-jump distance (−.57 ≤ r ≤ .22). Conclusions: The present findings indicate that, irrespective of sex, 35-cm drop heights are best suited to induce rapid and powerful DJ performance (ie, RSI) during reactive strength training in elite adolescent handball players. Moreover, training-related gains in DJ performance may at least partly translate to gains in horizontal jump and longer sprint distances (ie, ≥20-m) and/or vice versa in male and female elite adolescent athletes, irrespective of drop height.


2019 ◽  
Vol 31 (1) ◽  
pp. 99-106
Author(s):  
Kyle S. Beyer ◽  
Jeffrey R. Stout ◽  
Michael J. Redd ◽  
Kayla M. Baker ◽  
Haley C. Bergstrom ◽  
...  

Purpose: To examine the reliability and the maturity-related differences of fatigue thresholds (FTs) among youth males. Methods: Twenty-nine youth males (11–17 y) completed 2 ramp exercise tests on a cycle ergometer. Systemic FTs were calculated from gas exchange and ventilation variables. Localized FTs were calculated from electromyography and near-infrared spectroscopy of the vastus lateralis. All FTs were determined using the maximal distance method and expressed relative to maximal oxygen consumption. All participants were grouped according to the number of years from peak height velocity into PRE- (< −1.5 y), PERI- (−1.5 to +1.5 y) and POST- (> +1.5 y) peak height velocity. Reliability was assessed with intraclass correlation coefficients, and differences between groups were assessed with analysis of variance and Cohen’s d coefficients. Results: Analysis of variance revealed significant group differences with PRE having significantly greater systemic pulmonary FTs than POST, while localized muscular FTs were significantly greater in PRE when compared with PERI and POST. All FTs exhibited excellent reliability (intraclass correlation coefficient > .75) in all maturity groups. Conclusion: Maturity status appears to influence the onset of FTs among youth male athletes, with FTs occurring later in younger athletes. Furthermore, all FTs were reliable measures regardless of maturity.


Author(s):  
Edilson Hobold ◽  
Lucinar Jupir Forner Flores ◽  
Ricardo Brandt ◽  
Oldemar Mazzardo Junior ◽  
Miguel De Arruda

The aim of this study was to analyze the age of Peak Height Velocity (PHV), anthropometric variables and body composition of students from the western state of Paraná. he study included 1,011 male students aged 12-15 years from 11 municipalities located around the Itaipu lake. Anthropometric and body composition variables were obtained according to international criteria. Biological maturation was determined by age of PHV and for the purpose of analysis, it was categorized into developmental levels. The results reinforce, as expected, an increasing trend of variables analyzed as students advanced in maturity. hus, it was concluded that with the advancement of maturation, anthropometric variables maintain a linear growth observed in each PHV stratum. his linear trend is not observed in body composition. Body fat showed a decrease in average values as the individual approaches PHV.


2018 ◽  
Vol 6 (12) ◽  
pp. 232596711881104 ◽  
Author(s):  
Hans Jan Bult ◽  
Maarten Barendrecht ◽  
Igor Joeri Ramon Tak

Background: The relationship between injury risk (IR) in age groups and periods around peak height velocity (PHV) remains unclear. PHV is defined as the moment of the largest increase in body height. Purpose: To investigate injury risk and injury burden as functions of growth velocity (periods around PHV) and chronological age groupings (under 12 years [U12] to U19) in talented youth male soccer players. Study Design: Cohort study; Level of evidence, 2. Methods: A total of 170 players from the youth academy of a Dutch soccer club (highest professional league: Eredivisie) were observed for 1 to 3 seasons. Injuries, exposure, PHV age, and chronological age were registered. The injury incidence density (IID) and injury burden per 1000 hours of soccer participation, with 95% CIs, were calculated for 5 PHV periods and 7 age groups. These were compared with the overall cohort results using incidence ratios (IRs) and burden ratios (BRs) with 95% CIs. Results: The mean age at PHV was 14.4 ± 0.65 years (range, 12.8-16.5 years). The mean IID for the total cohort was 8.34 injuries per 1000 hours (95% CI, 7.71-9.02). Compared with the overall mean, a significantly higher IID was found for PHV period 4+5 (IR, 1.31 [95% CI, 1.00-1.71]; P = .049) and for the U15 group (IR, 1.49 [95% CI, 1.24-1.79]; P < .001). The overall injury burden was 58.37 injury days per 1000 hours (95% CI, 56.66-60.13). In PHV period 4+5, the injury burden was significantly higher (BR, 1.53 [95% CI, 1.39-1.68]; P < .001) when compared with the overall mean. Also, compared with the overall mean, the injury burden was higher in the U16 (BR, 1.48 [95% CI, 1.39-1.58]; P < .001), U15 (BR, 1.28 [95% CI, 1.19-1.38]; P < .001), and U17 groups (BR, 1.21 [95% CI, 1.13-1.31]; P < .001). Conclusion: Talented young soccer players were more prone to injuries during the 6 months after PHV (31% above overall mean) as well as in the U15 group (49% above overall mean). Based on the higher injury burden in the U16 (48%), U15 (28%), and U17 (21%) groups, we suggest that research on injury risk factors and preventive measures should primarily target these age groups. Additional interventions based on PHV may be of limited value from a screening perspective. Further research is needed on the interaction between age groups and PHV periods.


Sign in / Sign up

Export Citation Format

Share Document