scholarly journals Effects of hydrolyzed yeast supplementation on growth performance, immunity, antioxidant capacity, and microbial shedding in weaning pigs

2020 ◽  
Vol 13 (9) ◽  
pp. 1902-1909
Author(s):  
Waewaree Boontiam ◽  
Chalong Wachirapakorn ◽  
Phreerapong Phaengphairee

Background and Aim: Weaning pigs normally suffer from many stressors which have impaired growth performance and immunity. Hydrolyzed yeast has been proposed as an alternative feed additive. The aim of this study was to investigate the effects of various levels of hydrolyzed yeast (HY) supplementation in the feed of weaning pigs on growth performance, diarrhea incidence, immunity, antioxidant capacity, and microbial populations. Materials and Methods: A total of 144 crossbred weaning pigs (Duroc × Landrace × Large White) with a mean body weight (BW) of 7.46 kg were randomly assigned to one of four treatments during a 5-week feeding trial. Treatments consisted of a basal diet without HY inclusion (control), or the basal diet supplemented with HY at 0.5, 1.0, and 1.5 g/kg of diet, respectively. Results: Piglets fed with 1.0 or 1.5 g/kg HY presented significantly increased BW (p=0.009) and decreased incidence of diarrhea (p=0.001). The final BW (p=0.012), average daily gain (p=0.094), and average daily feed intake (p=0.091) showed a linear improvement with the level of HY inclusion. However, the gain-to-feed ratio was unaffected by dietary treatments. Linear responses to the HY supplementation levels were also observed for blood urea nitrogen (p=0.030), total protein (p=0.017), lymphocyte percentage (p=0.064), catalase activity (p=0.089), malondialdehyde (MDA) level (p=0.001), Salmonella spp. (p=0.024), Escherichia coli (p=0.021), and Lactobacillus spp. (p=0.048). Dietary inclusion of HY at 1.0 and 1.5 g/kg resulted in increased immunoglobulin A and G secretions (p=0.042 and p=0.022, respectively) and decreased MDA concentration (p<0.01) and Salmonella spp. (p=0.026) and E. coli (p=0.050). Conclusion: It was concluded that HY inclusion at 1.0 and 1.5 g/kg in the diet of weaning pigs improve BW, immunoglobulin secretion, and antioxidant enzyme activity, whereas it lowers diarrhea occurrence, lipid peroxidation, and pathogenic bacteria in weaning pigs.

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1394
Author(s):  
Jianyong Zhou ◽  
Jingyi Yao ◽  
Luhong Bai ◽  
Chuansong Sun ◽  
Jianjun Lu

EGF has been shown to stimulate the growth of animals. In this study, the content of EGF in chicken embryos (gallus EGF, gEGF) aged from 1 to 20 days of incubation were determined by ELISA kit, and the 5-day-old chicken embryos with the highest content of 5593 pg/g were selected to make gEGF crude extracts. A total of 1500 1-day-old Xianju chickens were randomly divided into five groups with six replicates of 50 chickens each. The control group was fed a basal diet, and other treatment diets were supplemented with 4, 8, 16 and 32 ng/kg gEGF crude extract, respectively. The experiment lasted for 30 days. Chicks were harvested at the end of the experiment, and liver, spleen, thymus, bursa and serum samples were collected. Results showed that average daily gain (ADG) and average daily feed intake (ADFI) of 16 ng/kg group were higher than those in the control group (p < 0.05). The serum uric acid (UA) of the 16 ng/kg group was reduced (p < 0.01), and the serum alkaline phosphatase (AKP) of the 16 ng/kg group increased (p < 0.01). The gEGF extract also increased chick’s antioxidant capacity, decreased malondialdehyde (MDA) and increased catalase (CAT) in the liver and serum of 16 ng/kg groups in compared to the control group (p < 0.01). Furthermore, immunity was improved by the addition of gEGF to broiler diets. The serum immunoglobin A (IgA) content of 8 and 16 ng/kg groups and the serum immunoglobin M (IgM) content of 4 and 8 ng/kg groups were increased (p < 0.05) compared to the control group. The bursa index of each experimental group was higher than the control group (p < 0.01). These findings demonstrate that the crude extract of gEGF prepared in this experiment could improve the growth performance, antioxidant capacity and immunity of broilers.


2020 ◽  
Vol 98 (12) ◽  
Author(s):  
Daolin Mou ◽  
Dajiang Ding ◽  
Shuang Li ◽  
Hui Yan ◽  
Binting Qin ◽  
...  

Abstract Selenium (Se) is an essential trace element for animals and exists in nature in both inorganic and organic forms. Although organic Se is more bioavailable than inorganic Se, there are inconsistent reports on the effect of organic Se on the reproductive performance of sows. This study was conducted to investigate the effect of maternal organic Se (2-hydroxy-4-methylselenobutanoic [HMSeBA]) supplementation on reproductive performance and antioxidant capacity of sows, and the long-term effect on the growth performance and antioxidant capacity of their offspring with or without lipopolysaccharide (LPS) challenge. The experimental design used in this study was a completely randomized design; 45 Landrace × Yorkshire sows were randomly allocated to receive one of the following three diets during gestation: control diet (Control, basal diet, n = 15), sodium selenite (Na2SeO3)-supplemented diet (Na2SeO3, basal diet + 0.3 mg Se/kg Na2SeO3, n = 15), and HMSeBA-supplemented diet (HMSeBA, basal diet + 0.3 mg Se/kg HMSeBA, n = 15). On day 21 of age, male offspring from each group were injected with LPS or saline (n = 6). As compared with the control group, maternal HMSeBA supplementation increased the number of total born piglets, while decreased birth weight (P &lt; 0.05). In the first week of lactation, maternal HMSeBA supplementation increased litter weight gain compared with the Na2SeO3 group (P &lt; 0.05) and increased the average daily gain of piglets compared with the control group and Na2SeO3 group (P &lt; 0.05). Meanwhile, maternal HMSeBA supplementation decreased piglet birth interval as compared with the control group and Na2SeO3 group (P &lt; 0.05). Besides, plasma glutathione peroxidase (GSH-Px) activity was higher in the HMSeBA group on farrowing 0 min and 90 min, while malondialdehyde (MDA) concentration was lower on farrowing 0, 90, and 135 min than those in the control group (P &lt; 0.05). In addition, maternal HMSeBA supplementation increased the concentration of selenoprotein P (SELENOP) in colostrum compared with the control group (P &lt; 0.05). Further study revealed that the LPS-challenged HMSeBA group had higher GSH-Px and total antioxidant capacity and lower MDA in weaning piglets compared with the LPS-challenged control group (P &lt; 0.05). Taken together, maternal HMSeBA supplementation increased the number of total born piglets, shortened the duration of farrowing, improved the antioxidant capacities of sows and their offspring, and improved the growth performance of suckling pigs at the first week of lactation. Thus, HMSeBA supplementation during gestation has the potentiality to produce more kilogram of meat.


2019 ◽  
Vol 99 (4) ◽  
pp. 840-847
Author(s):  
X. Liu ◽  
Y.S. Han ◽  
I.H. Kim

The present experiment was to evaluate the effects of dietary Spirulina (SP) supplementation in growing pigs. A total of 140 pigs [(Landrace × Yorkshire) × Duroc, 25.32 ± 1.36 kg] were randomly distributed to one of four treatments: control, basal diet; treatment 1, basal diet + 0.025% SP; treatment 2, basal diet + 0.050% SP; and treatment 3, basal diet + 0.100% SP. Growing pigs fed 0.050% SP diet had greater (P < 0.05) body weight and fecal Lactobacillus counts compared with pigs fed basal diet. Average daily gain and gain to feed ratio were greater (P < 0.05) in pigs fed 0.050% and 0.100% SP diets as compared with pigs fed basal diet. The apparent total tract digestibility (ATTD) of dry matter (DM) and superoxide dismutase (SOD) activity for pigs fed 0.050% SP diet tended to increase compared with pigs fed basal diet (P < 0.10). Pigs fed 0.025%, 0.050%, and 0.100% SP had a higher (P < 0.05) glutathione peroxidase (GPx) activity than pigs fed basal diet. In conclusion, SP supplementation improved growth performance and ATTD of DM, increased the SOD and GPx activity, and enhanced the fecal Lactobacillus counts in growing pigs.


2015 ◽  
Vol 18 (3) ◽  
pp. 557-564 ◽  
Author(s):  
S. Mohana Devi ◽  
S.I. Lee ◽  
I.H. Kim

Abstract Phytogenic feed additives have become attractive alternatives for use in animal diets. The objective of the present study was to evaluate the effect of a phytogenic-based feed additive on growth performance, nutrient digestibility, blood profiles, fecal noxious gas emission, and intestinal morphology of weaning pigs after dietary challenge with E. coli K88. A total of 120 crossbred pigs [(Yorkshire × Landrace) × Duroc)] with an initial body weight (BW) of 6.09 ± 0.96 kg (21 d of age) were assigned randomly to 1 of the 4 dietary treatments. Each pen housed 5 pigs, and there were 6 pens/treatment. Treatments included: T1, negative control (without antibiotics); T2, T1 + antibiotic; T3, T1 + 0.05% phytogenics; and T4, T1 + 0.2% commercial mix of organic acids. Overall, the average daily gain (ADG) with the T3 treatment was higher (P<0.05). At wk 1, the apparent total tract digestibility (ATTD) of dry matter (DM) was increased (P<0.05) with T4 treatment. The ATTD of ash with T3 and T4 treatments was greater (P<0.05). At wk 3, pigs fed with the T4 diet had a significantly higher (P<0.05) ATTD of DM. The ATTD of ash and calcium (Ca) was significantly increased (P<0.05) with the T4 treatment. Pigs fed with the T3 diet had a higher (P<0.05) ATTD of phosphorus (P). At wk 6, the ATTD of ash was significantly increased (P<0.05) with the T1 and T3 treatments. The data indicate that phytogenics positively affect growth performance of weaning pigs, indicating that their use as an alternative in the diets of weaning pigs can significantly improve ADG, under challenge with E.coli K88.


2020 ◽  
Vol 98 (7) ◽  
Author(s):  
Hayden E Williams ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
Steven S Dritz ◽  
Michael D Tokach ◽  
...  

Abstract A total of 140 weanling pigs (241 × 600, DNA, Columbus, NE; initially 5.5 ± 0.79 kg body weight) were used in a 32-d study evaluating the effects of increasing dietary Fe from either iron sulfate (FeSO4) or iron carbonate (FeCO3) on nursery pig growth performance and blood Fe status. The pigs used for this trial did not receive an Fe injection after birth in order to increase the sensitivity to added dietary Fe after weaning. Pigs were weaned at approximately 21 d and allotted to pens based on the initial weight in a completely randomized block design with five pigs in each pen and four pens per treatment. Experimental treatments were arranged as a 2 × 3 + 1 factorial with main effects of dietary Fe source (FeSO4 vs. FeCO3) and level (10, 30, or 50 mg/kg of added Fe) plus a negative control with no additional dietary Fe. The basal diet contained 40 mg/kg total dietary Fe based on ingredient contributions and was formulated with an Fe-free trace mineral premix. Experimental diets were formulated below the pigs recommended Fe requirement based on NRC (2012) estimates. Experimental diets were fed in pellet form in a single phase for the duration of the trial. From day 0 to 32, there was no evidence for source × level interactions for growth performance, hemoglobin (Hb), or hematocrit (Hct) values. There was no evidence for a difference (P &gt; 0.10) in dietary Fe source. Providing increasing Fe levels in the diet from either FeSO4 or FeCO3 improved (P &lt; 0.05) average daily gain, average daily feed intake, gain-to-feed ratio, and increased (P &lt; 0.05) Hb and Hct values. A day effect (P = 0.001) was observed for both Hb and Hct with values increasing throughout the study. Increasing dietary Fe levels in the diet from either FeSO4 or FeCO3 increased (linear; P &lt; 0.05) Hb and Hct values on days 14, 21, and 32. In summary, these data suggest that the micronized form of FeCO3 is a source of Fe that can be added to nursery diets to yield similar responses to those observed from FeSO4 supplementation. Similar to previous research, increasing dietary Fe improved the growth performance and increased Hb and Hct values when pigs have low Fe status at weaning.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 397-398
Author(s):  
Sujie Liu ◽  
Jian Wang ◽  
Tengfei He ◽  
Hansuo Liu ◽  
Xiangshu Piao

Abstract A total of 168 one-day old broilers (average BW 46.4 ± 0.6 g) were selected to determine effects of natural capsaicin extract (NCE) as a substitute for chlortetracycline (CTC) on performance, antioxidant capacity, immune function and meat quality of broilers [Founded by NSFC (31772612)]. Broilers were randomly allotted into 3 dietary treatments (n = 7) including a corn-soybean meal basal diet (CON), a basal diet + 75 mg/kg CTC (CTC), and a basal diet + 80 mg/kg NCE (NCE). The experiment contained phase 1 (day 1 to 21) and 2 (day 22 to 42). Compared with CON, broilers from NCE showed higher average daily gain at all stages (P &lt; 0.05). On day 42, organic matter, crude protein and gross energy digestibilities of broilers from NCE were higher than those from the other two groups (P &lt; 0.05). Higher percentage of bursa of Fabricius was observed in broilers fed NCE diets compared with CON (P &lt; 0.05). Trypsin and lipase activities in the pancreas of broilers from NCE were higher than those from CON (P &lt; 0.05). Breast muscle of broilers fed NCE diets showed lower L* values compared with CON (P &lt; 0.05). Broilers from NCE also showed higher levels of serum total antioxidant capacity, glutathione peroxidase, superoxide dismutase, lower levels of interleukin-1β and tumor necrosis factor-α compared with broilers offered CON diets (P &lt; 0.05). Compared with CON, lower concentrations of serum urea-N, low-density lipoprotein cholesterol and total cholesterol, higher growth hormone level were observed in broilers fed NCE diets (P &lt; 0.05). In conclusion, supplementing 80 mg/kg of NCE to diets could improve growth performance, nutrient digestibility, antioxidant and immune function, and meat quality of broilers. Moreover, broilers fed NCE diets exhibited similar growth performance and health status to those offered chlortetracycline (CTC) diets.


2021 ◽  
Vol 6 (4) ◽  
pp. 650-658
Author(s):  
Md Manirul Islam ◽  
Meherunnesa Chowdhury Sumy ◽  
Kona Adhikary ◽  
Priunka Bhowmik

The study was conducted to evaluate the effects of olive leaves with probiotics (OLP) on growth performance, carcass characteristics, meat quality, blood parameters and oxidative stability of meat in broiler. A total of 160 day old, unsexed Cobb-500 chicks were distributed in to five dietary treatment groups: Control (Basal diet), OLP-1 (Basal diet + 0.4% OLP, DM basis), OLP-2 (Basal diet + 0.8% OLP, DM basis), OLP-3 (Basal diet + 1.2% OLP, DM basis) and OLP-4 (Basal diet + 1.6% OLP, DM basis) having 4 replications with 8 birds in each in a completely randomized design. Results showed that the live weight, overall average daily gain (ADG) increased significantly (p<0.05) in all treatment groups compared to control. The weekly feed conversion ratio (FCR) reduced significantly (p<0.05) in 0-14 days and the weekly ADG improved in 15-28 days. Blood cholesterol and high density lipoprotein (HDL) increased significantly (p<0.05) in all treatment groups except OLP-4 compared to control. The dressing percentage showed significant (p<0.05) difference among treatment groups and control. Organs weight were similar among treatment groups, although the breast meat and bursa weight differed significantly (p<0.05) in treatment groups. A significant increase (p<0.05) in meat crude protein (CP) and total ash content in treatment groups relative to control. Meat thiobarbituric acid reactive substances (TBARS) significantly (p<0.05) decreased at 0.8%, 1.2% and 1.8% during 1st, 2nd, 3rd weeks and in average value as well. Net return and benefit cost ratio (BCR) substantially increased in all treatment groups compared to control (p<0.05). Finally, dietary OLP supplementation improved growth performance, meat CP and ash content, increased blood cholesterol, HDL content, net rutrun and BCR while reduced meat TBARS value. Thus, olive leaf probiotics can be a potential source to be used as feed additive in broiler. Asian J. Med. Biol. Res. December 2020, 6(4): 650-658


Agriculture ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 83
Author(s):  
Qingyu Sun ◽  
Haiming Yang ◽  
Jun Yu ◽  
Jingru Liang ◽  
Xuean Xu ◽  
...  

This experiment aimed to investigate effects of the different dietary levels of vitamin E (VE) on the growth performance, immunity and antioxidant capacity of goslings. A total of 240 1-day-old, male Jiangnan white goslings were selected and randomly divided into 6 groups. Each treatment included five replicates. The basal diet was supplemented with 6 concentrations of VE (0, 12, 24, 36, 48 and 60 mg DL-α-tocopherol acetate/kg). The results were as follows: (1) The α-tocopherol content in the serum and liver of goslings increased linearly as supplemental VE increased in diet (p < 0.05). (2) The body weight (BW) and average daily gain (ADG) increased quadratically with increasing dietary VE supplementation (p < 0.05). Dietary VE supplementation could significantly reduce the feed/gain ratio (F/G) (p < 0.05). (3) Dietary supplementation with VE could significantly improve the contents of immunoglobulin A (IgA) and immunoglobulin G (IgG) in the serum of the goslings (p < 0.05). The content of interferon-γ (IFN-γ) in the serum was significantly reduced with VE supplementation (p < 0.05). (4) Dietary supplementation with VE could significantly improve serum and liver catalase (CAT), superoxide dismutase (SOD) activities and liver total antioxidant capacity (T-AOC) (p < 0.05); Serum and liver MDA contents were significantly reduced with VE supplementation (p < 0.05). In summary, dietary supplementation with VE could improve growth performance, immunity and antioxidant capacity. Based on broken-line regression analysis, the dietary VE supplementation level for ADG was 12.51 mg/kg, but higher supplementation level should be considered to improve immunity and antioxidant capacity.


2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 199-200
Author(s):  
Woo Jung Seok ◽  
Lei Cheng ◽  
Thanapal Palanisamy ◽  
Xiangting Fu ◽  
In Ho Kim

Abstract This study aimed to evaluate the effects of supplemental Bacillus licheniformis derived-protease in diets on growth performance, apparent total tract digestibility (ATTD), and fecal microbial shedding in post-weaned growing pigs. In total, 90 crossbred (Landrace × Yorkshire × Duroc) weaner pigs with an initial average BW of 6.61 ± 1.73 kg were randomly allotted into 2 treatments with 9 replicate pens of 5 pigs for a 4-phase feeding trial (0 to 1, 1 to 3, 3 to 6, and 6 to 11 weeks). The treatments were: CON, corn-soybean meal based basal diet; PROT, basal diet + 0.05% protease. The basal diet contained 16.32, 15.91, 15.49, and 14.91 MJ/kg digestibility energy respectively and 1.50, 1.40, 1.30, and 1.00% lysine respectively for phase 1, 2, 3, and 4. All data were statistically analyzed by Student’s t-test of SAS 9.4 (SAS Institute Inc., Cary, NC, USA). Variability in the data was expressed as mean ± standard deviation, differences with P &lt; 0.05 were considered to be statistically significant. During phase 3, average daily gain, and gain: feed ratio was increased (P &lt; 0.05) in pigs fed PROT diet compared with those fed CON diet. Pigs fed PROT diet had higher (P &lt; 0.05) ATTD of dry matter and crude protein than pigs fed CON diet. No differences were observed in fecal microflora counts between CON and PROT groups. Dietary supplementation of Bacillus licheniformis derived-protease increased growth performance at phase 3 and increased the digestibility) of dry matter and crude protein (insert mean values for both Con vs Treat) in growing pigs.


2018 ◽  
Vol 98 (3) ◽  
pp. 488-497 ◽  
Author(s):  
D.H. Nguyen ◽  
S.I. Lee ◽  
J.Y. Cheong ◽  
I.H. Kim

A total of 180 crossbred pigs [(Landrace × Yorkshire) × Duroc] with an average body weight of 22.61 ± 1.23 kg were used in an 18 wk study to determine the effect of protease and bromelain in low-protein diets in grower–finisher pigs. Dietary treatments included: T1, basal diet treatment; T2, low-protein treatment; T3 (T2 + 0.2 g kg−1 protease); and T4 (T2 + 0.3 g kg−1 bromelain). Pigs fed protease- and bromelain-supplemented diets increased average daily gain and gain to feed ratio at week 18, dry matter and nitrogen digestibility at week 6, as well as energy digestibility at week 12, compared with low-protein diet (P < 0.05). Pigs fed T3 and T4 diets led to a trend of decreased (P < 0.05) blood urine nitrogen (BUN) and creatinine concentrations at the 12th wk. A reduction of ammonia (NH3) and hydrogen sulfide (H2S) emission was observed in pigs fed the dietary protease and bromelain supplementation at the 6th wk (P < 0.05). There was no effect on all parameters between the protease and bromelain supplementation treatments. In conclusion, supplementation of protease and bromelain to low-protein diet enhanced growth performance, nutrient digestibility, and reduced NH3 and H2S in growing–finishing pigs.


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