scholarly journals Recent trends of glucose-6-phosphate dehydrogenase deficiency among saudi population in Riyadh city

2019 ◽  
Vol 35 (6) ◽  
Author(s):  
Fatmah Said Abdullah Al Qahtany

G6PD deficiency is associated with erythrocyte deficiency in the X-chromosome enzyme. It causes a hematologic syndrome called hemolytic anemia that connects G6PD deficiency with X-linked condition. In the Middle East, including Saudi Arabia, G6PD deficiency is the most dominant genetic blood disorders. It results in higher rates of mortality and morbidity due to its incurable long-lasting nature and prevalence of physical and psychological incapacities. In this study, an attempt was made to evaluate the prevalence of G6PD deficiency among the Saudi population in Riyadh city. A cross-sectional retrospective study was conducted at King Saud University Medical City in Riyadh, Saudi Arabia. The population of the study comprised randomly chosen males and females who visited the hospital from January 2017 to January 2018. Statistical analyses were performed using SPSS, and descriptive analysis was used to find the frequency of G6PD-deficient patients. Out of the 209 patients, 62.2% were males (n=130) and 37.8% were females (n=79). Twenty males and 6 females were found to have G6PD deficiency, with the male to female ratio being 1:3. Out of the total 130 male participants, 20 patients were found to be enzyme deficient and 6 patients of 79 female patients were found to be G6PD deficient. There were 38.4% (n=10) patients with G6PD level <4 units/gram hemoglobin, 26.9% (n=7) patients had G6PD levels of 4.1–7.0 units/gram hemoglobin, and 34.6% (n=9) patients had >7 units/gram hemoglobin. Among the G6PD patients, 23.07% patients were severely anemic, and 5 (19.2%) patients were reported to have high bilirubin. The present study revealed the G6PD prevalence to be 12.4% among the Saudi population; this value is significantly higher than that found in France, Spain, India, and Singapore. In the Saudi population, males are more vulnerable to G6PD-deficient than females. Hence, attention should be paid to G6PD-deficient patients while prescribing antimalarial medication. Such patients may be advised to avoid certain foods to minimize the risk of having hemolytic episodes.

2019 ◽  
Vol 10 (4) ◽  
pp. 15
Author(s):  
Fakhr M. Alayoubi ◽  
Mohamed Rashrash ◽  
Yasmin Alsharawy ◽  
Samha Alayoubi ◽  
Wed A. Alayoubi ◽  
...  

Objective: The study sought to assess the prevalence and the risk factors associated with anemia among male and female young adults in (Riyadh city, Saudi Arabia). Methods: A cross-sectional study was conducted at King Saud University and Alfaisal University in September 2016 among young adults aged 18 to 28 years old. Data were collected using an interview questionnaire. Additionally, the respondents were evaluated clinically and via laboratory testing for anemia. Results: Our study population showed a higher percentage of men as compared to women participants. About half of our study sample had a lightly active lifestyle, and more than one-third of the study participants were overweight (34.7%). The average age of the respondents was 22.08 ± 1.98 years. The only factor significantly associated with anemia was gender, in that female gender showed a positive association with anemia. Conclusion:  The most explicit risk factor for anemia among Saudi individuals of college and young professional ages was the female gender. Dietary lifestyle, heavy menstruation, pregnancy, and intake of non-steroidal anti-inflammatory drugs were additional important risk factors among these individuals, but they were statistically not significant.   Article Type: Original Research


2021 ◽  
Vol 14 (02) ◽  
pp. 803-813
Author(s):  
Tasneem H. Ali Fathi ◽  
Shaima Ali Miraj

Background: The current study was premeditated to evaluate the attitude, knowledge and practice of the pharmacy employees (including interns and trainees) dealing with medical practice towards medical errors and adverse drug reaction reports. Methods:The study is a quantitative, descriptive, cross-sectional one with the influence of medication-error reporting, focused on pharmacy department of King Saud University Medical City, Riyadh, Saudi Arabia using the Likert-scale survey. The research population was 167 pharmacy employees, (including interns, and trainees) from King Saud University Medical City. The legalized items connected to knowledge, attitude and practices (KAP) survey was given to each member. Results:Majority of the total sample size (n=167) are pharmacists, managers, lead pharmacists, pharmacist-in-charge, or staff pharmacist by 74.3 %, where 15.6 % are pharmacy technicians, 7.8 % are pharmacy students interns/externs and 2.4 % other workers. Positive responses were highest in teamwork within the pharmacy employee (87.3% vs. 81.6%), staff training and skills within the pharmacy employee (86.35% vs. 79.25%), physical space and environment in the pharmacy (83.8% vs. 73.6%). Lower responses were found in response to mistakes (79.75% vs. 74.4%) compared to community pharmacy database report (AHRQ, 2019).Conclusion:The findings indicate that ratings on documenting mistakes (reporting)as perceived by pharmacy employee are at par with the community pharmacy elsewhere. The weakest dimension identified was mistakes (reporting) having the lowest positive response with a mean score of 3. This denotes a low level of agreement according to Likert scale confirming that is the dimension needing improvement.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Reema M. Alhussein ◽  
Mansoor M. Albarrak ◽  
Abdulaziz A. Alrabiah ◽  
Nawfal A. Aljerian ◽  
Hashim M. Bin Salleeh ◽  
...  

Abstract Background Most sudden cardiac arrests occur at home, with low rates of bystander cardiopulmonary resuscitation being performed. We aimed to assess knowledge of cardiopulmonary resuscitation among individuals in Riyadh City, Saudi Arabia, who are not involved in health care. Methods A community-based cross-sectional study was conducted between January and February 2020 in 4 different areas in Riyadh City: North, South, East, and West. The participants were surveyed using a validated self-administered questionnaire. The Statistical Package for Social Sciences version 25.0 was used for inferential statistics and binary logistic regression analysis. Results A total of 856 participants completed the questionnaire, 51.8% were unaware of cardiopulmonary resuscitation. Only 4.4% of the participants had attended a formal cardiopulmonary resuscitation training course, 5.1% were campaign attendees, and 38.7% acquired their experience through the media. Having a higher level of education was positively associated with having knowledge of cardiopulmonary resuscitation. The main concern among attendees of cardiopulmonary resuscitation training courses and campaigns was legal issues, whereas inadequate knowledge was the major barrier for those who had learned about cardiopulmonary resuscitation through the media. Conclusion The level of knowledge of cardiopulmonary resuscitation among non-health care individuals in Riyadh City was found to be insufficient. Therefore, coordinated efforts among different authorities should be considered to implement a structured strategy aiming to increase awareness and knowledge of cardiopulmonary resuscitation among non-health care individuals.


Author(s):  
Saleh Alghamdi

Objectives: The use of herbal medicines as non-conventional treatment is popular, especially in developing countries where people suffering from chronic diseases as diabetes mellitus are more likely to use herbal medicines along with conventional medicines. However, their simultaneous use may concur serious drug interactions and may therefore result in a serious outcome. The present study was designed to identify the most commonly used herbal medicines and conventional anti-diabetic medications among Saudi population. Methods: A cross-sectional survey was developed and piloted.Data were retrieved and manually entered in Excel 2016. Frequencies and percentages were utilized to perform descriptive analysis. The study was approved by the Scientific and Research Committee of the main hospital taking part in the study. Results: A total of 347 responses were recorded (69.4% response rate). 54% of participants were male, 53% were between the age of 41 and 64 years, and 35.5% had no formal education. Black tea, Peppermint, ginger, green tea, olive oil, and black seed were among the frequently mentioned herbal medicines. Black tea was used by the majority of patients (80%) while peppermint and ginger were used by more than half of patients, i.e., (56.5%) and (52.7%) respectively. Least common herb used by patients was Artemisia species (2.8%). A majority of patients (53.4%) used traditional medicine at least once daily, and 83% used traditional medicine without their physician's prescription. Conclusion: Concomitant use of herbal and conventional anti-diabetic medication was a common practice among patients in Saudi Arabia, therefore, pharmacists-led educational programs should target both prescribers and general public about the possible interactions/risks of herbal medicines.


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Ahmed A. Al-Sayed ◽  
Abdualltef H. Al-Rashoudi ◽  
Abdulrhman A. Al-Eisa ◽  
Abdullah M. Addar ◽  
Abdullah H. Al-Hargan ◽  
...  

Introduction.Medical students experience significant psychological stress and are therefore at higher risk of using sedatives. There are currently no studies describing the prevalence of sedative drug use among medical students in Saudi Arabia. The aim of this study was to evaluate the prevalence and factors associated with sedative drug use among medical students in Saudi Arabia.Materials and Methods.A cross-sectional convenience sampling study gathered data by anonymous questionnaire from students enrolled at the King Saud University College of Medicine in 2011. The questionnaires collected data regarding social and demographic variables, sleep patterns, and the use of stimulant and sedative drugs since enrollment. Sedatives were defined as any pharmaceutical preparations that induce sleep.Results and Discussion.Of the 729 students who returned questionnaires, 17.0% reported sedative drug use at some time since enrollment. Higher academic year, lower grade point average, regular exercise, fewer hours of sleep per day, poorer quality of sleep, and the presence of sleeping disorders were found to be significantly associated with sedative drug use.Conclusions.Further study is required to increase our understanding of sedative drug use patterns in this relatively high-risk group, as such understanding will help in the development of early intervention programs.


2014 ◽  
Vol 4 (1) ◽  
pp. 9-13
Author(s):  
Salih Binsalih ◽  
Omar Al Harthi ◽  
Mohammad Qahtani ◽  
Abdullah Al Sayyari

Objective: To determine if inpatients in medical wards are aware who their most responsible physician (MRP) is and what is the nature of his/her specialty and if this awareness is influenced by age, sex, method of admission and the length of hospital stay. Methods: A cross-sectional study conducted at King Abdulaziz Medical City, Riyadh. Results: One hundred patients completed the survey from 7 different wards. 66% were male and two-thirds of the patients were over the age of 60 years, and 55% were inpatients for more than 10 days. Overall respondents, 43% knew the name of their MRP whereas 57% did not. Conclusion: Reduced awareness was more often observed in female gender, older age and being admitted through Emergency Department. It's recommended that MRPs' names on signboards be written in Arabic and English in all wards.


Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3401
Author(s):  
Nora A. Althumiri ◽  
Mada H. Basyouni ◽  
Faisal Saeed Al-Qahtani ◽  
Mohammed Zamakhshary ◽  
Nasser BinDhim

Background: Bariatric surgery is known as the most effective treatment resulting in long-term weight loss for obesity. However, behavioral changes, including food preference, food allergies, and consumption, between groups of patients who underwent bariatric surgery in comparison with people who did not have bariatric surgery have not been fully discussed in the literature. Objective: The aim of this article is to describe patient-reported changes of perception related to food preferences, consumption, and food allergies in participants who underwent bariatric surgery and to compare their food consumption with participants who did not have bariatric surgery in Saudi Arabia. Methodology: This study is a secondary analysis of the Sharik Diet and Health National Survey (SDHNS) conducted in July 2021. Quota sampling was utilized to generate balanced distributions of participants by age and gender across all administrative regions of Saudi Arabia. Data collection included sociodemographic information (age, gender, and educational level), as well as food habits and the consumption of various food categories. Results: Of the 6267 potential participants contacted in 2021 from the 13 administrative regions of Saudi Arabia, 5228 successfully completed the interview, with a response rate of 83.4%. Gender was distributed equally among the total participants in the sample. The prevalence of bariatric surgeries in Saudi Arabia was estimated at around 4.1% of the total sample. More than 36% of people who had bariatric surgery experienced food taste changes, and around 15% reported a decrease in allergic reactions to food. Moreover, 68.1% had food preference changes, either starting to favor a new food or no longer favoring one. There was a significant association between consuming more red meat, chicken, and energy drinks and a decreased consumption of grains and rice among those who had the bariatric surgery compared with those who did not. Conclusions: This study found that more than two-thirds of people who had bariatric surgery self-reported food taste and food preference changes. More studies should be performed on the Saudi population, including clinical follow-up, to better understand these changes.


2018 ◽  
Vol 5 (2) ◽  
pp. 3560-3564 ◽  
Author(s):  
Zeeshan H Ahamed ◽  
Abdulaziz Alwakeel ◽  
Abdulelah Alrshedan ◽  
Fahad Altimsah

Objective: The present study was planned with an aim to evaluate the knowledge and awareness regarding root canal treatment in a sample of Saudi population. Material and methods: A cross-sectional questionnaire-based survey was conducted among a sample of participants in the Saudi population. Participants were asked questions to assess their knowledge about endodontic treatment. Results: A total of 568 patients (343 males and 225 females) participated in the study. When the patient’s responses were analyzed regarding endodontic treatment, it was found that 68.55 % of participants had a good experience of root canal treatment in the past. 27.9% of the respondents describe their knowledge of root canal treatment as average. Spontaneous toothache was considered the most important factor to seek endodontic treatment in majority (40.1%) of the participants and 86.6% of the participants preferred a specialist to undergo a root canal treatment. Conclusion: Pain associated with root canal treatment was the most important factor that dithered the surveyed participants from root canal treatment. The results of the survey reveal an improvement of knowledge and awareness of patients about root canal treatment


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