scholarly journals Sleep disorders in acute and chronic pain

2021 ◽  
Vol 13 (3) ◽  
pp. 125-130
Author(s):  
M. G. Poluektov ◽  
A. O. Golovatyuk

Pain is one of the leading causes of decline in quality of life. When pain syndromes occur, a person may experience unpleasant sensory sensations and concomitant disorders, which can lead to pain aggravation and sleep disturbances. According to experimental studies, increased pain sensation with reduced sleep duration occurs due to opioid, serotonergic, noradrenergic, and dopaminergic antinociceptive systems dysfunction. In clinical practice, a reduction in sleep duration is usually associated with insomnia, which is the most common sleep disorder. In pain syndromes, insomnia occurs in 53–90% of patients (for comparison: in the general population – in 7.4%). Non-pharmacological (cognitive-behavioral therapy) and pharmacological approaches are used in insomnia treatment. Some medications (amitriptyline, mirtazapine, trazodone, gabapentin, pregabalin) have both hypnotic and analgesic effects, which allows to use them for pain syndromes with sleep disturbances. It has been shown that the correction of sleep disorders can reduce the severity and frequency of pain.

Author(s):  
Dmitry Fedorovich Khritinin ◽  
M. A. Sumarokova ◽  
E. P. Schukina

Currently, insomnia is not only a medical, but also a social as well as an economic problem. Sleep disorders increase the risk of somatic, neurological and mental illnesses. The shift schedule has a significant impact on the employee’s health, increasing the risk of developing such disorders as metabolic syndrome, arterial hypertension and other. As a result of sleep disturbances, lipid peroxidation processes may intensify, which can lead to the disorders described above. Therefore, the prevention and treatment of sleep disorders is an important aspect of chronic diseases diagnostics. In our opinion, it is crucial to study possible sleep disorders for their timely correction. The article discusses the features of drug and non-drug treatment of sleep disorders, as well as approaches to the primary and secondary prevention of insomnia. It is recommended to begin the treatment of sleep disorders with cognitive-behavioral therapy. Cognitive-behavioral therapy for insomnia typically includes psycho-education, training in relaxation techniques, stimulation limitation method, sleep limitation therapy, and cognitive therapy. When developing recreational activities for employees with a shift work schedule, attention should be paid to work and rest regimes, prevention of fatigue and obesity, and the sleep disorders treatment. Training in sleep hygiene and improving its compliance in the target groups is regarded as a method of non-pharmacological treatment of sleep disorders and a means of primary and secondary prevention of insomnia. In our opinion, further research on the features of the prevention and treatment of insomnia in various population groups is needed. Effective primary and secondary prevention of sleep disorders will reduce the risks of developing neurological, somatic and mental diseases and significantly improve the quality of life.


2021 ◽  
pp. 111-120
Author(s):  
N. V. Vashchenko ◽  
A. I. Kozhev ◽  
Ju. E. Azimovа

Migraine and sleep disorders are common in the general population, may be associated with each other and often significantly reduce patients’ quality of life. Clinicians and epidemiological studies have long acknowledged a link between these conditions. However, the exact nature of this relationship, its underlying mechanisms and patterns are complex and not fully understood. This publication brings together the latest data on the relationship between migraine and sleep disorders: the biochemical and functional-anatomical background, the mutual influence of these conditions on each other and the typical sleep disturbances in migraine patients (such as insomnia, obstructive sleep apnea, parasomnia, snoring, excessive daytime sleepiness). The paper discusses the hypotheses of pathogenetic relationships based on the studies of the central nervous system’s anatomical and physiological features in people with migraine and sleep disorders. The available data should encourage physicians to evaluate sleep quality in migraineurs and use combination therapy systematically. The therapy of insomnia is reviewed: both nonpharmacological and pharmacological therapies are discussed; the advantages of an integrated approach are discussed, and a brief overview of each group of medications is offered.Lastly, a case study of a patient with chronic migraine and insomnia treated with Doxylamine in combination therapy is presented. Treatment with Doxylamine significantly reduced the incidence of insomnia, probably thereby positively influencing the course of migraine as well.


CNS Spectrums ◽  
2007 ◽  
Vol 12 (S10) ◽  
pp. 3-5 ◽  
Author(s):  
Thomas Roth

AbstractInsomnia is a disorder characterized by chronic sleep disturbance associated with daytime disability or distress, such as memory impairment and fatigue, that occurs despite adequate opportunity for sleep. Insomnia may present as difficulty falling/staying asleep or as sleep that is nonrestorative. Studies show a strong correlation between insomnia and impaired quality of life. Pain conditions and depression are commonly associated with insomnia, either as secondary or comorbid conditions. In addition, a greater incidence of anxiety, alcohol and drug dependence, and cardiovascular disease is found in people with insomnia. Data indicate insomnia results from over-engaged arousal systems. Insomnia patients experience increased metabolic rate, body temperature, and heart rate, and elevated levels of norepinephrine and catecholamines. Pharmacologic options for the treatment of insomnia include benzodiazepine hypnotics, a selective melatonin receptor agonist, and sedating antidepressants. However, insomnia may be best treated with cognitive-behavioral therapy and instruction in good sleep hygiene, either alone or in concert with pharmacologic agents. Studies on the effects of insomnia treatment use variable methodologies or do not publish negative results, and there are currently no studies of treatment focusing on morbidity. Further research is necessary to better understand the effects of insomnia therapies on medical and psychiatric disorders.In this Clinical Information Supplement, Thomas Roth, PhD, describes the nature of insomnia and its pathophysiology. Next, Andrew D. Krystal, MD, MS, reviews morbidities associated with insomnia. Finally, Joseph A. Lieberman III, MD, MPH, provides an overview of therapeutics utilized in patients with insomnia, including behavioral therapies and pharmacologic options.


Author(s):  
Abha Singh ◽  
Abha Daharwal ◽  
Avinashi Kujur

Background: Sleep disturbance is one of frequent sign and symptom encountered in post-menopausal women. It affects the quality of the life and may lead to depression in some women. Objective of present study was to find out the prevalence of sleep disorder in post-menopausal womenMethods: Prospective study done on the post-menopausal women coming to Gynaecology OPD of Dr Bheem Rao Ambedkar Hospital, Raipur. This study was a prospective cross sectional observational study, conducted in the outpatient department of Obstetrics and Gynecology from 1st August 2016 to 31st January 2017. It included 500 women of postmenopausal age. A detail Performa was provided to assess sleep patterns and disorders associated with it. All the data was analysed using chi square testResults: The prevalence of sleep disturbances was 29.58%. Home makers were affected more in comparison to working women, 71,43% women had problems in initiating sleep. About 2/3rd women in the study group developed insomnia within 5 years of menopause, whereas 1/3rd took more than 7years to develop insomnia. Co morbidities were present in 48% women. Our women have mean age of menopause around 45 years.Conclusions: Sleep disorders are common, with prevalence of 29.5% in menopausal women in present study. It significantly causes psychosocial problems in women. There is need for it to be asked for and to be treated promptly.


2017 ◽  
pp. 97-102
Author(s):  
M. G. POLUEKTOV ◽  
P. V. PCHELINA

Circadian rhythms and the mechanisms of sleep and wakefulness begin to form in the embryonic period and undergo many stages of development before acquire characteristics typical for an adult. Structure of sleep disturbances in children also differs from that in the adult population. Most sleep disorders in children are the result of immaturity of certain brain structures and mechanisms: primary sleep disorders, pediatric behavioral insomnia, sleepwalking, night terrors, enuresis. These disorders are benign, and usually disappear by adulthood. Treatment of benign sleep disorders in children should primarily be based on the methods of behavioral therapy, the rules of sleep hygiene and the purpose of light sedation.


2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Mariana Castanho Risso

Sleep disorders are currently a major public health issue in Brazil, due to its high incidence and difficult diagnosis, identification of type and treatment.1 Rheumatic disorders have been associated with changes in sleep state, which cause reduction in quality of life, eventually reduced by the chronic inflammatory process of the primary disease.2–6 This study aimed to identify and describe the existence of sleep disturbances in patients with psoriatic arthritis, as well as to verify possible association of sleep disorders with metabolic syndrome and other parameters in these individuals. Thirty one patients with psoriatic arthritis from a Rheumatology Outpatient Clinic were analyzed. Three sleep assessment questionnaires were employed: Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (EPW) and The Berlin Questionnaire (BQ). Sleep walking or talking were also inquired as a complementary scale. Sociodemographic variables and the presence of hypertension, obesity, diabetes, dyslipidemia and metabolic syndrome have also been investigated. On average, sleep disorders were found in 54.83% of the studied patients (64.5% from PSQI, 51.6% from EPW and 48.4% from Berlin) and around 70% of sleep disorders in patients with simultaneous diagnosis of metabolic syndrome and psoriatic arthritis. From these results, it is notable that sleep disorders are common in patients diagnosed with psoriatic arthritis. Thus, this pathology demands greater attention in clinical practice and search for ideal and complete therapy, in addition to simultaneous control of arthritis, sleep, hypertension, dyslipidemia and obesity.


2020 ◽  
Vol 117 (3) ◽  
pp. 58-67
Author(s):  
Anastasiia Shkodina ◽  
Kateryna Tarianyk ◽  
Dmytro Boiko

The article summarizes the arguments and counter-arguments within the scientific discussion on the impact of sleep disorders on the development of cognitive decline in patients with Parkinson's disease. The main purpose of the study is to study the possibility of predicting the development of cognitive decline by assessing the severity of sleep disorders and their differences in the presence of cognitive impairment. Systematization of literature sources and approaches to solving the problem showed that sleep disorders develop in the early stages of Parkinson's disease and are often accompanied by cognitive impairment. Cognitive decline is manifested throughout Parkinson's disease and ranges from moderate in the early stages to dementia in the late stages. The relevance of the study of the relationship between sleep disorders and cognitive functions lies in the possibility of further improving the prediction of the development of cognitive decline in order to effectively correct it. Treatment of sleep disorders can be accompanied by improved memory and even morphological changes in the brain. Therefore, the question arises about the possibility of correcting cognitive decline by influencing sleep disorders. The methodology of the study included assessment of the overall status of patients on a unified scale of Parkinson's disease, Montreal cognitive rating scale and sleep scale in Parkinson's disease. The duration of the study was 8 months. Patients with Parkinson's disease were selected as the study. The article presents the results of a survey of patients who show that patients with Parkinson's disease and cognitive decline showed a predominance of motor disorders, sleep disorders and the overall score on the sleep scale in Parkinson's disease. In the presence of cognitive decline more pronounced disorders of motor functions in everyday life, which can lead to sleep disorders and its quality. The study empirically confirms and theoretically proves that the assessment of sleep disorders can be used to predict the risk of developing cognitive impairment in patients with Parkinson's disease. The results of this study may be useful for improving the early diagnosis and prevention of cognitive impairment in patients with Parkinson's disease, which, in turn, leads to improved quality of treatment of these patients. Such changes can directly affect the choice of therapeutic tactics and improve the quality of life of patients with Parkinson's disease. The question of the features of various sleep disorders and their prognostic value in relation to cognitive decline in patients with various forms of Parkinson's disease remains open.


2018 ◽  
Vol 7 (2) ◽  
pp. 135-161
Author(s):  
A.I. Melehin

The article shows that in the treatment of chronic insomnia in geriatric patients, it is recommended to use a step-by-step treatment and start with steps aimed at the elimination of somatic, environmental and psychological barriers which affect the quality of sleep. An algorithm for the evaluation of sleep disorders at a later age firstly desctibed. The specifics of the clinical and psychological evaluation of the quality of sleep in geriatric patients presented. Evidence on the effectiveness of pharmacological and non-pharmacological approaches for the treatment of chronic insomnia at a later age presented on the basis of a number of foreign studies. It is recommended to use multicomponent cognitive-behavioral psychotherapy as a first-line treatment of chronic insomnia at a later age Types, forms and structural components of cognitive-behavioral therapy of chronic insomnia in the elderly are detailed. Practical difficulties and reccomentations for the use of medical approach in the treatment of sleep disorders in the elderly are also presented.


Author(s):  
Md Moyazzem Hossain ◽  
Md Habibur Rahman

Background and Objective: Insufficient sleep duration as well as quality is becoming endemic in our modern society. The time of going to bed and sleep quality and quantity are linked with students’ learning abilities and academic accomplishment. Therefore, this paper firstly opted to measure the level of sleep quality of the students of Jahangirnagar University, Savar, Dhaka-1342, Bangladesh, and finally detect the association between quality of sleep and academic achievement among the students. Materials and Methods: The primary data were collected through a self-administered questionnaire from 334 students with a response rate about 84 percent during February to March 2019. Pittsburgh Sleep Quality Index (PSQI) was used to measure the sleep quality of the students. The percent distribution, descriptive statistics, and multiple regression were employed to identify the influence of the components of sleep quality on academic performance. Results: Only the sleep quality of one-fourth of the students was good. Moreover, sleep duration, subjective sleep quality, and daytime dysfunction were positively related to the academic performance; however, sleep latency, sleep disturbances, use of sleeping medications, and habitual sleep efficiency were inversely associated with the academic performance of the students. Conclusion: Academic performance of a student was related to the components of sleep quality. Thus, this study indicates that students with poor academic performance have problems regarding sleep issues. Medical advice should be followed to maintain a healthier lifestyle including adequate rest time.


Author(s):  
Aishwarya Gonzalez Cherubal ◽  
S. Pooja ◽  
Vijaya Raghavan

Background: Sleep disorders can act as risk factors and even aggravate underlying conditions. With prevalence of 17% in general population, hypertension is a leading cause of morbidity and mortality in India. Though hypertension has various well established risk factors like family history, sedentary lifestyle, poor diet, smoking and age, sleep is often an understudied and overlooked factor. Body mass index is another important risk factor for various physical conditions. Associations between sleep and body mass index have been documented in many studies around the world. Although a consensus is yet to be drawn, many studies highlight that BMI related disorders could be predicted by sleep duration and quality. Materials and Methods: Two hundred consecutive hypertensive patients who were attending the OPD for follow-up were included as participants in this study after obtaining an informed consent. A semi structured proforma was designed to elicit the socio demographic profile of the participants. Each participant was assessed for the presence of sleep disorders by sleep-50 questionnaire and quality of sleep by the Pittsburgh Sleep Quality Index (PSQI). Results: Results found that BMI was significantly correlated with sleep quality, sleep duration, and sleep disorder. Hypertension was not significantly correlated to sleep quality or duration but associated to sleep disorder. Conclusion: This study found that body mass index was significantly correlated with sleep variables such as sleep duration, sleep quality, and sleep disorders. Maintaining a healthy BMI could in fact impact the amount and quality of sleep an individual receives.


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