scholarly journals Mood Worsening on Days with High Pollen Counts is associated with a Summer Pattern of Seasonality

Pteridines ◽  
2019 ◽  
Vol 30 (1) ◽  
pp. 133-141 ◽  
Author(s):  
Faisal Akram ◽  
Tyler B. Jennings ◽  
John W. Stiller ◽  
Christopher A. Lowry ◽  
Teodor T. Postolache

Abstract Background: Summer/spring-type seasonal affective disorder (S-SAD) is the less common subtype of seasonal affective disorder and evidence regarding potential triggers of S-SAD is scarce. Recent reports support association of airborne-pollen with seasonal exacerbation of depression (mood seasonality) and timing of suicidal behavior. Therefore, we hypothesized that Old Order Amish (OOA) with summer/spring pattern of seasonality (abbreviated as summer pattern) and S-SAD will have significant mood worsening on high pollen days. Methods: A seasonal pattern of mood worsening and SAD parameters were estimated using Seasonal Pattern Assessment Questionnaire (SPAQ). Age- and gender-adjusted ANCOVAs and post hoc analyses were conducted to compare mood worsening on days with high pollen counts between summer-pattern vs no-summer-pattern of mood worsening, S-SAD vs no-S-SAD, winter-pattern vs no-winter-pattern of mood worsening, and W-SAD vs no-W-SAD groups. Results: The prevalence of S-SAD was 0.4%, while 4.5% of individuals had a summer pattern of mood seasonality. A statistically significant difference for mood worsening on high pollen days was observed between summer-pattern vs no-summer-pattern of mood worsening (p = 0.006). The significant association between S-SAD vs no-SAD groups (p = 0.032) for mood worsening on high pollen days did not withstand Bonferroni adjustment for multiple comparisons. No significant association was found for winter-pattern vs no-winter-pattern of mood worsening (p = 0.61) and for W-SAD vs no-W-SAD (p = 0.19) groups. Conclusion: Our results are consistent with previous studies implicating links between aeroallergen exposure and summer pattern of seasonality, but not the winter pattern of seasonality.

1994 ◽  
Vol 7 (1_suppl) ◽  
pp. 29-33 ◽  
Author(s):  
B. Martinez ◽  
S. Kasper ◽  
S. Ruhrmann ◽  
H.-J. Möller

Seasonal affective disorder (SAD) represents a subgroup of major depression with a regular occurrence of symptoms in autumn/winter and full remission in spring/summer. Light therapy (LT) has become the standard treatment of this type of depression. Apart from this, pharmacotherapy with antidepressants also seems to provide an improvement of SAD symptoms. The aim of this controlled, single-blind study was to evaluate if hypericum, a plant extract, could be beneficial in treating SAD patients and whether the combination with LT would be additionally advantageous. Patients who fulfilled DSM-III-R criteria for major depression with seasonal pattern were randomized in a 4-week treatment study with 900 mg of hypericum per day combined with either bright (3000 lux, n = 10) or dim (< 300 lux, n = 10) light condition. Light therapy was applied for 2 hours daily. We found a significant (MANOVA, P < .001) reduction of the Hamilton Depression Scale score in both groups but no significant difference between the two groups. Our data suggest that pharmacologic treatment with hypericum may be an efficient therapy in patients with seasonal affective disorder.


1997 ◽  
Vol 9 (2) ◽  
pp. 71-76 ◽  
Author(s):  
R.H. Van Den Hoofdakker ◽  
M.C.M. Gordijn

The present explosive growth of interest in the therapeutic possibilities of exposure to light was triggered by a patient, Herbert Kern. He suffered from episodic depressive and manic complaints and discovered, by registering these over the years, a seasonal pattern in their occurrence. Discussions with scientists of the NIMH resulted in his participation in a bright light-treatment experiment when he was depressed in the winter of 1980-1981. He recovered.Next, the same group of investigators defined the criteria for a new syndrome, Seasonal Affective Disorder (SAD): a history of major affective disorder (according to the Research Diagnostic Criteria), at least two consecutive years in which the depressions have occurred during fall or winter and remitted in the following spring or summer, and the absence of any clear-cut seasonally changing psychosocial variable, such as work, stress and so on.


2002 ◽  
Vol 180 (5) ◽  
pp. 394-395 ◽  
Author(s):  
Tony Kendrick

In this issue, Eagles et al report that people suffering from seasonal affective disorder (SAD) are heavy users of primary health care services (Eagles et al, 2002, this issue). Nearly 10% of patients attending practices in Aberdeen screened positive for SAD using the Seasonal Pattern Assessment Questionnaire (SPAQ; Rosenthal et al, 1987), among whom around half of those attending for interview fulfilled DSM–IV (American Psychiatric Association, 1994) criteria for recurrent major depression with seasonal pattern. The patients with SAD had consulted significantly more frequently over a 5-year period, with a variety of symptoms both related and unrelated to SAD, and had received significantly more prescriptions, investigations and referrals than patients found not to fulfil the criteria for SAD.


2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Sherri Melrose

Seasonal affective disorder or SAD is a recurrent major depressive disorder with a seasonal pattern usually beginning in fall and continuing into winter months. A subsyndromal type of SAD, or S-SAD, is commonly known as “winter blues.” Less often, SAD causes depression in the spring or early summer. Symptoms center on sad mood and low energy. Those most at risk are female, are younger, live far from the equator, and have family histories of depression, bipolar disorder, or SAD. Screening instruments include the Seasonal Pattern Assessment Questionnaire (SPAQ). Typical treatment includes antidepressant medications, light therapy, Vitamin D, and counselling. This paper provides an overview of SAD.


1986 ◽  
Vol 3 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Marilyn A. Cooper ◽  
Claudine Sherrill ◽  
David Marshall

Attitudes toward physical activity were examined in relation to sports classification (nonambulatory vs. ambulatory) and gender for elite cerebral palsied athletes and were compared to attitudes of elite Canadian able-bodied athletes (Alderman, 1970). Subjects were 165 CP adult athletes who competed in the 1983 National CP Games, Ft. Worth, Texas. Data were collected by interview on the Simon and Smoll Attitude Toward Physical Activity Scale (SATPA). SATPA answers were treated with MANOVA and ANOVA, and the Scheffé test was used for post hoc analysis. No significant difference was found among class, gender, and class-by-gender combinations in attitudes toward physical activity. Adult CP athletes have positive attitudes toward the total concept of physical activity, but are significantly less favorably disposed to physical activity as a thrill and as long and hard training than as social experience, health and fitness, beauty, and tension release.


2012 ◽  
Vol 27 (5) ◽  
pp. 369-371 ◽  
Author(s):  
M. Delavest ◽  
C. Even ◽  
N. Benjemaa ◽  
M.-F. Poirier ◽  
R. Jockers ◽  
...  

AbstractThis case-control study found an association between Seasonal Affective Disorder (SAD) and a single nucleotide polymorphism (intronic rs2072621) of the gene encoding GPR50 (an orphan member of the G protein-coupled melatonin receptor subfamily) in females. This may represent a gender-specific risk factor and a molecular link between melatonin and SAD.


2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Cecilia Rastad ◽  
Lennart Wetterberg ◽  
Cathrin Martin

Background. There is a need for more knowledge on the effects of light room treatment in patients with seasonal affective disorder and to explore patients’ subjective experience of the disease and the treatment.Methods. This was a descriptive and explorative study applying qualitative content analysis. A purposeful sample of 18 psychiatric outpatients with a major depressive disorder with a seasonal pattern and a pretreatment score ≥12 on the 9-item Montgomery-Åsberg Depression self-rating scale was included (10 women and 8 men, aged 24–65 years). All patients had completed light room treatment (≥7/10 consecutive weekdays). Data was collected two weeks after treatment using a semistructured interview guide.Results. Patients described a clear seasonal pattern and a profound struggle to adapt to seasonal changes during the winter, including deterioration in sleep, daily rhythms, energy level, mood, activity, and cognitive functioning. Everyday life was affected with reduced work capacity, social withdrawal, and disturbed relations with family and friends. The light room treatment resulted in a radical and rapid improvement in all the major symptoms with only mild and transient side effects.Discussion. The results indicate that light room treatment is essential for some patients’ ability to cope with seasonal affective disorder.


2020 ◽  
Author(s):  
Gülsüm Duruk ◽  
Esra Laloglu

Abstract Objective : YKL-40, a new biomarker of localized inflammation, is secreted by macrophages and regulates inflammation and immune responses. The aim of this study was to investigate YKL-40 levels in saliva and compare the level of this mediator in healthy and unhealthy oral cavity. Methods: 85 children (46 girls, 39 boys), aged 6-15 (mean±SD: 9.15±2.16) were included in this study. The children were divided into three groups: Group-I (control, n=25, DMFT/dmft=0), Group-II (n=30, exist of localized dental caries) and Group-III (n=30, exist of localized advanced dental caries). Gingival index (GI), plaque index (PI), DMFT/dmft, DMFS/dmfs, and the number of advanced dental caries according to the ICDAS II and PUFA/pufa index were recorded. Saliva was collected and YKL-40 concentrations were measured. One-way ANOVA with Tukey post hoc, Kruskal-Wallis, multiple regression analysis, and Sperman’s correlation tests were used for statistical analysis. Results: The highest level of YKL-40 was obtained in group III , followed by groups II and I , respectively (p<0.01). In Group II, DMFT/dmft scores and the number of caries (DT/dt) were higher than in group III (p<0.01). In group III, there was a statistically significant correlation between YKL-40 levels in saliva and the number of advanced dental caries. In addition, there was no statistically significant difference in terms of age and gender (p>0.05). Conclusion: Advanced dental caries, rather than DMFT/dmft score, may play an important role in the increasing levels of YKL-40 in saliva.


2002 ◽  
Vol 180 (5) ◽  
pp. 449-454 ◽  
Author(s):  
John M. Eagles ◽  
Fiona L. Howie ◽  
Isobel M. Cameron ◽  
Samantha M. Wileman ◽  
Jane E. Andrew ◽  
...  

BackgroundLittle is known about the presentation and management of seasonal affective disorder (SAD) in primary care.AimsTo determine the use of health care services by people suffering from SAD.MethodFollowing a screening of patients consulting in primary care, 123 were identified as suffering from SAD. Each was age— and gender-matched with two primary care consulters with minimal seasonal morbidity yielding 246 non-seasonal controls. From primary care records, health care usage over a 5-year period was established.ResultsPatients with SAD consulted in primary care significantly more often than controls and presented with a wider variety of symptoms. They received more prescriptions, under went more investigations and had more referrals to secondary care.ConclusionsPatients with SAD are heavy users of health care services. This may reflect the condition itself, its comorbidity or factors related to the personality or help-seeking behaviour of sufferers.


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