Alcohol-Based Sanitizers: An Effective Means for Preventing the Spread of Contagious Viral Diseases Including COVID-19

2021 ◽  
Vol 58 (6) ◽  
pp. 416-426
Author(s):  
Narendra Kumar Chaudhary ◽  
Biswash Guragain ◽  
Summi Rai ◽  
Nabina Chaudhary ◽  
Rahul Chaudhary ◽  
...  

Abstract The global community is struggling with the highly contagious COVID-19. Returning to \normal life" now poses risks, and the use of appropriate protective measures has become necessary to continue daily life and protect public health. The main protective measures to prevent transmission of COVID-19 are masks, soaps and disinfectants. Because coronavirus is a \lipid-enveloped virus", it is very sensitive to lipid-dissolving chemicals and can therefore be effectively removed by washing hands sufficiently with soap and water. However, using an alcohol-based disinfectant is a more viable option for outdoor use. Alcohol-based disinfectants are inexpensive, immediately effective, easy to use and better tolerated by the skin compared to other disinfectants. WHO recommends disinfectants containing 75% isopropanol or 80% ethanol as highly effective in inactivating the SARS-CoV-2-virus. The current review discusses the role of alcohol-based hand sanitizers (ABHS) in preventing the spread of viruses, their side effects on human health, and suggests the use of alcohol-based sanitizers as potentially effective in combating the current epidemic.

Author(s):  
Akshay Vaidya

Viral infections remain major “worldwide” cause of morbidity and mortality.  Herbal extracts or wholesome drugs have been in use for medicinal purposes since ancient time and are known for their antiviral properties and more tolerable side effects. Thus, naturally based pharmacotherapy is a proper alternative for treating viral diseases. Hence this article describes potential antiviral properties of medicinal plants against diverse group of viruses and suggests screening the potential of plants possessing broad spectrum anti-viral effects against viral diseases. Guduchyadi Kwath is a polyherb ayurvedic preparation useful in various diseases. It is useful in pitta vikar, shleshma vikar, Jwara, Chardi, Daha, Trushna, and Agnimandya1. According to modern science it showed anti-inflammatory, antioxidant, antibacterial, antiviral, antimalarial, hepatoprotective, wound healing and immune-modulatory action. The study is aim to the effect of “Guduchyadi kashaya” on viral diseases.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Kayo Augusto de Almeida Medeiros ◽  
Bárbara Justo Carvalho ◽  
Leonardo Zumerkorn Pipek ◽  
Gustavo Heluani Antunes de Mesquita ◽  
Fernanda Nii ◽  
...  

AbstractDespite inguinal hernias being a common problem in public health, there is still scarce information about the epidemiology of the complications, especially incarceration, and their influence on the laparoscopic surgical methods considering the role of the learning process of the surgeon. Compare laparoscopic totally extraperitoneal (TEP) approach in the repair of incarcerated and non-incarcerated inguinal hernias from the perspective of technical difficulty for trained surgeons. We obtained data about sex, age, location and type of hernia, surgery duration, ASA score, postoperative complications, previous surgeries and BMI. Groups were descriptively analyzed and statistically compared to verify how similar the samples were. 265 (90.1%) patients had non-incarcerated hernias and 29 (9.9%) incarcerated. We observed that there was no significant difference in the pattern of location (right, left or bilateral), sex, ASA, previous or complications between the two groups. Unilateral incarcerated hernias had longer operative times compared to non-incarcerated. No difference was found between bilateral hernias. We didn´t find significant epidemiological differences between incarcerated and non-incarcerated hernias. In our experience, with the limitation of a single-surgeon series, laparoscopic hernia repair achieved satisfactory results in terms of feasibility (especially for bilateral hernias) and safety.


Author(s):  
Marianna Isaakidou ◽  
Emmanouil Zoulias ◽  
Marianna Diomidous

The aim of this work is to shortly provide the public with an overview about fake news and artificial intelligence (AI) technology. Especially in our days, where there is a high speed of spreading news, the impact of fake news on public health is crucial and the development of valid and effective means of technology to support the provision of safe and trustworthy information about public health issues is vital. The role of informatics in health area is profoundly important and AI in public health, so people will be able to distinguish the genuine information from the fake one.


2021 ◽  
Vol 12 ◽  
Author(s):  
Martina Vacondio ◽  
Giulia Priolo ◽  
Stephan Dickert ◽  
Nicolao Bonini

Efforts to contain the spread of the coronavirus emphasize the central role of citizens’ compliance with self-protective behaviors. Understanding the processes underlying the decision to self-protect is, therefore, essential for effective risk communication during the COVID-19 pandemic. In the present study, we investigate the determinants of perceived threat and engagement in self-protective measures in the United Kingdom, Italy, and Austria during the first wave of the pandemic. The type of disease (coronavirus vs. seasonal flu) and the type of numerical information regarding the disease (number of recovered vs. number of dead) were manipulated. Participants’ cognitive and emotional risk assessment as well as self-reported engagement in protective behaviors were measured. Results show that worry was the best predictor of perceived threat in all countries. Moreover, a path analysis revealed that worry and perceived threat serially mediated the effect of type of disease on engagement in self-protective behaviors. The numerical framing manipulation did not significantly impact behavior but had a direct effect on worry and an indirect effect on perceived threat. These results are in line with theoretical accounts that identify emotions as a central determinant for risk perception. Moreover, our findings also suggest that effective risk communication during the COVID-19 pandemic should not stress comparisons to other, well-known viral diseases, as this can ultimately reduce self-protective behaviors.


2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Fatemeh Malekvandfard ◽  
Leila Zare ◽  
Seyedeh Sahar Mortazavi Farsani ◽  
Mahsa Motavaf

: In recent decades, infertility is becoming a public health issue. Male spermatogenesis failure has been considered a major contributory factor to infertility. Mammalian spermatogenesis is a well-defined process, requiring highly regulation processes in both transcriptional and the posttranscriptional levels. Discovery of microRNAs (miRNAs or miR) as essential class of gene expression regulators has provided new insights into a multitude of biological processes including spermatogenesis. In current review study, we first provide a short overview of spermatogenesis process, and then focus on recent studies that have elucidated the essential role of miRNAs in different steps of sperm production.


2018 ◽  
Vol 6 (9) ◽  
pp. 478-486
Author(s):  
Daniela Cipu ◽  
Dan Simion Cipu ◽  
Agneta Maria Pusztai ◽  
Anca Alexandra Matusz

Bronchopulmonary neoplasm is the first cause of cancer mortality in the world and a major public health problem, affecting 17% of men and 12% of women; in this context it is very important and necessary to establish the correct diagnosis in the early stages of the disease in order to initiate the required surgical therapy [1]


2021 ◽  
Vol 11 ◽  
Author(s):  
Nahid Akhtar ◽  
Rabia Ayoubi ◽  
Vinaypreet Kour ◽  
Umesh Goutam ◽  
M. Amin-ul Mannan

Abstract: Fungal diseases cause more deaths as compared to combined deaths due to malaria and tuberculosis. There are around 3.8 million fungal species, but only about 300 of them are pathogenic to humans. Invasive fungal diseases are majorly caused by Aspergillus, Candida, Cryptococcus, Histoplasma, Mucorales, and Pneumocystis. It has been estimated that around 1.5 million people die because of these infections across the globe. The emergence of resistance against the major classes of antifungal drugs poses a serious threat to public health. Moreover, the commonly used antifungal drugs are loaded with side effects. Some of them are nephrotoxic, hepatotoxic, cause cardiomyopathy, and in acute cases, cytotoxicity. Hence, it is important to seek novel molecules that can be safe and effective antifungal drugs. Naturally occurring molecules in plants and various microorganisms can be a safe and effective alternative to the existing antifungal drugs. In this review, the role of various phytochemicals such as alkaloids, flavonoids, saponins, and phenols as potential antifungal agents has been discussed. Similarly, naturally occurring molecules in other microorganisms like algae, bacteria, and various other fungi have been summarized. The information discussed in this review can be useful in the identification of novel antifungals.


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