Nickel Oxide-incorporated Polyaniline/Polyvinyl Alcohol Composite for Enhanced Antibacterial Activity

2019 ◽  
Vol 233 (9) ◽  
pp. 1261-1274 ◽  
Author(s):  
Gul Rahman ◽  
Mansoor Khan ◽  
Zahid Khan ◽  
Anwar-ul-Haq Ali Shah ◽  
Muhammad Saleem Khan ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Polyvinyl Alcohol ◽  
Nickel Oxide ◽  
Antibacterial Agent ◽  
Composite Films ◽  
Cost Effective ◽  
Single Step ◽  
Bacterial Strains ◽  
X Ray Diffraction ◽  
E Coli

Abstract The development of biocompatible, cost effective and more efficient materials to control or inhibit the growth of microorganisms in necessary to fight against resistant microbes. Here, we demonstrate the synthesis of nickel oxide-incorporated polyaniline/polyvinyl alcohol (PANI/PVA/NiOx) composite material by single-step polymerization and its application as antibacterial agent. The composite films were characterized using UV-visible spectroscopy (UV-Vis), Thermogravimetric analysis (TGA), Fourier Transform Infrared spectroscopy (FTIR), X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM). UV-Vis spectra revealed the enhancement in absorption properties of PANI/PVA/NiOx with optimum 5% incorporation of NiOx. TGA results indicated slightly enhanced thermal stability of the PANI/PVA/NiOx composite film as compared to PANI/PVA. FTIR spectra for composites revealed the existence of NiOx in polymers. However the crystallinity of PANI/PVA was not much affected. The antibacterial activity of the prepared composites was examined against four different gram negative bacteria, Salmonella, Shigella, Pseudomonas and Escherichia coli (E. coli). The composite exhibited excellent antibacterial activity against E. coli, Salmonella and Shigella while pseudomonas showed some resistance. Based on the results, PANI/PVA/ NiOx (5%) composite showed the highest activity against the tested bacterial strains, thus showing its potential to be used as an effective antibacterial agent.

Antibacterial Activity of Thujaoccidentalis,ThujaorientalisandChamaecyparisobtusa

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Kyoung- Sun Seo ◽  
Seong Woo Jin ◽  
Seongkyu Choi ◽  
Kyeong Won Yun
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Antibacterial Agent ◽  
Methanol Extract ◽  
The Other ◽  
Diffusion Method ◽  
E Coli ◽  
Agar Diffusion ◽  
Agar Diffusion Method ◽  
Crude Methanol Extract

The antibacterial activity of three Cupressaceae plants (Thujaoccidentalis,ThujaorientalisandChamaecyparisobtusa) was tested against three bacteria using the agar diffusion method. The ether and ethylacetate fraction of crude methanol extract from the three plants showed potent antibacterial activity against the tested microorganisms. The result showed that Staphylococcus aureus revealed the most sensitivity among the tested bacteria. Thujaoccidentalisether fraction and Thujaorientalis hexane fraction exhibited the highest antibacterial activity against Staphylococcus aureus. E. coli was shown the highest MIC values compared to the other two tested bacteria, which indicates the lowest antibacterial activity against the bacterium. This study promises an interesting future for designing a potentially active antibacterial agent from the three Cupressaceae plants.

Temperature Dependent On Activated Carbon For Their Biological Activity And Photocatalytical Degradation of Methylene Blue: A Novel Approach To Green Synthesis

2021 ◽  
Author(s):  
Amalanathan.M ◽  
Aravind.M ◽  
Sony Michael Mary.M ◽  
Razan A. Alshgari ◽  
Asma A. Alothman ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Antibacterial Activity ◽  
Activated Carbon ◽  
Hydrothermal Carbonization ◽  
Microbial Pathogens ◽  
X Ray Diffraction ◽  
E Coli ◽  
Novel Approach ◽  
Transmission Electron ◽  
Ft Ir

Abstract In this work, jasmine flower derived activated carbon were successfully synthesized by hydrothermal carbonization process at the different annealing temperature. The Crystallinity, phase, structural, morphological and optical properties of activated carbon were investigated using X-ray diffraction (XRD), Fourier Transform Infrared spectroscopy (FT-IR), Scanning electron microscopy (SEM), Transmission electron microscope (TEM), and UV-visible spectroscopy analysis. The graphitic phase of carbon was obtained from the XRD pattern. Surface morphology reveals irregular-shaped nanoparticles. The photodegradation of methylene blue (MB) was carried out under the visible light irradiation technique to study its photocatalytic activity. The activated carbon obtained at 400oC, 500oC and 600oC shows a photocatalytic degradation efficiency of 86%, 90%, and 94%, respectively. Antibacterial activity of activated carbon was examined against S. Aureus (MTCC-737) and E-Coli (MTCC- 443) microbial pathogens, and their potent antibacterial activity was examined from the zone of inhibition layer.

scholarly journals Synthesis and Characterization of a Bioartificial Polymeric System with Potential Antibacterial Activity: Chitosan-Polyvinyl Alcohol-Ampicillin

Molecules ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 3109 ◽  
Author(s):  
Andres Bernal-Ballen ◽  
Jorge Lopez-Garcia ◽  
Martha-Andrea Merchan-Merchan ◽  
Marian Lehocky
Keyword(s):  
Antibacterial Activity ◽  
Polyvinyl Alcohol ◽  
Statistical Significance ◽  
Antibacterial Properties ◽  
Intermolecular Forces ◽  
Polymeric System ◽  
Bacterial Strains ◽  
Natural Polymers ◽  
The Matrix ◽  
The Individual

Bio-artificial polymeric systems are a new class of polymeric constituents based on blends of synthetic and natural polymers, designed with the purpose of producing new materials that exhibit enhanced properties with respect to the individual components. In this frame, a combination of polyvinyl alcohol (PVA) and chitosan, blended with a widely used antibiotic, sodium ampicillin, has been developed showing a moderate behavior in terms of antibacterial properties. Thus, aqueous solutions of PVA at 1 wt.% were mixed with acid solutions of chitosan at 1 wt.%, followed by adding ampicillin ranging from 0.3 to 1.0 wt.% related to the total amount of the polymers. The prepared bio-artificial polymeric system was characterized by FTIR, SEM, DSC, contact angle measurements, antibacterial activity against Staphylococcus aureus and Escherichia coli and antibiotic release studies. The statistical significance of the antibacterial activity was determined using a multifactorial analysis of variance with ρ < 0.05 (ANOVA). The characterization techniques did not show alterations in the ampicillin structure and the interactions with polymers were limited to intermolecular forces. Therefore, the antibiotic was efficiently released from the matrix and its antibacterial activity was preserved. The system disclosed moderate antibacterial activity against bacterial strains without adding a high antibiotic concentration. The findings of this study suggest that the system may be effective against healthcare-associated infections, a promising view in the design of novel antimicrobial biomaterials potentially suitable for tissue engineering applications.

scholarly journals Alkaloid-Rich Crude Extracts, Fractions and Piperamide Alkaloids of Piper guineense Possess Promising Antibacterial Effects

Antibiotics ◽  
2018 ◽  
Vol 7 (4) ◽  
pp. 98 ◽  
Author(s):  
Eunice Mgbeahuruike ◽  
Pia Fyhrquist ◽  
Heikki Vuorela ◽  
Riitta Julkunen-Tiitto ◽  
Yvonne Holm
Keyword(s):  
Antibacterial Activity ◽  
Pathogenic Bacteria ◽  
Bacterial Resistance ◽  
Hot Water ◽  
Bacterial Strains ◽  
Inhibitory Effects ◽  
Piper Guineense ◽  
E Coli ◽  
Growth Inhibitory ◽  
Derivatives Of

Piper guineense is a food and medicinal plant commonly used to treat infectious diseases in West-African traditional medicine. In a bid to identify new antibacterial compounds due to bacterial resistance to antibiotics, twelve extracts of P. guineense fruits and leaves, obtained by sequential extraction, as well as the piperine and piperlongumine commercial compounds were evaluated for antibacterial activity against human pathogenic bacteria. HPLC-DAD and UHPLC/Q-TOF MS analysis were conducted to characterize and identify the compounds present in the extracts with promising antibacterial activity. The extracts, with the exception of the hot water decoctions and macerations, contained piperamide alkaloids as their main constituents. Piperine, dihydropiperine, piperylin, dihydropiperylin or piperlonguminine, dihydropiperlonguminine, wisanine, dihydrowisanine and derivatives of piperine and piperidine were identified in a hexane extract of the leaf. In addition, some new piperamide alkaloids were identified, such as a piperine and a piperidine alkaloid derivative and two unknown piperamide alkaloids. To the best of our knowledge, there are no piperamides reported in the literature with similar UVλ absorption maxima and masses. A piperamide alkaloid-rich hexane leaf extract recorded the lowest MIC of 19 µg/mL against Sarcina sp. and gave promising growth inhibitory effects against S. aureus and E. aerogenes as well, inhibiting the growth of both bacteria with a MIC of 78 µg/mL. Moreover, this is the first report of the antibacterial activity of P. guineense extracts against Sarcina sp. and E. aerogenes. Marked growth inhibition was also obtained for chloroform extracts of the leaves and fruits against P. aeruginosa with a MIC value of 78 µg/mL. Piperine and piperlongumine were active against E. aerogenes, S. aureus, E. coli, S. enterica, P. mirabilis and B. cereus with MIC values ranging from 39–1250 µg/mL. Notably, the water extracts, which were almost devoid of piperamide alkaloids, were not active against the bacterial strains. Our results demonstrate that P. guineense contains antibacterial alkaloids that could be relevant for the discovery of new natural antibiotics.

Antibacterial Activity Inhibition after the Degradation of Flumequine by UV/H2O2

2011 ◽  
Vol 14 (1) ◽  
Author(s):  
Caio Rodrigues da Silva ◽  
Milena Guedes Maniero ◽  
Susanne Rath ◽  
José Roberto Guimarães
Keyword(s):  
Antibacterial Activity ◽  
Broad Spectrum ◽  
Antibacterial Agent ◽  
Veterinary Drug ◽  
Drug Resistant ◽  
Bacterial Strains ◽  
Activity Inhibition

AbstractFlumequine is a broad-spectrum antibacterial agent of the quinolone class widely used as veterinary drug in food-producing animals. It is considered as pseudo-persistent compound continuously introduced into the environment and its presence in the environment may contribute to the development of drug resistant bacterial strains. In this study antibacterial activity removal during flumequine degradation by UV/H

scholarly journals Design, Synthesis and Antibacterial Activity of Coumarin-1,2,3-triazole Hybrids Obtained from Natural Furocoumarin Peucedanin

Molecules ◽  
2019 ◽  
Vol 24 (11) ◽  
pp. 2126 ◽  
Author(s):  
Alla V. Lipeeva ◽  
Danila O. Zakharov ◽  
Liubov G. Burova ◽  
Tatyana S. Frolova ◽  
Dmitry S. Baev ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Cycloaddition Reaction ◽  
Bacterial Strains ◽  
Design Synthesis ◽  
Docking Simulations ◽  
E Coli ◽  
Antibiotic Drugs ◽  
In Vitro Antibacterial Activity ◽  
Substituted Coumarins

Synthesis of 1,2,3-triazole-substituted coumarins and also 1,2,3-triazolyl or 1,2,3-triazolylalk-1-inyl-linked coumarin-2,3-furocoumarin hybrids was performed by employing the cross-coupling and copper catalyzed azide-alkyne cycloaddition reaction approaches. The synthesized compounds were evaluated for their in vitro antibacterial activity against Staphylococcus aureus, Bacillius subtilis, Actinomyces viscosus and Escherichia coli bacterial strains. Coumarin-benzoic acid hybrids 4с, 42с and 3-((4-acetylamino-3-(methoxycarbonyl)phenyl)ethynyl)coumarin (29) showed promising activity against S. aureus strains, and the 1,2,3-triazolyloct-1-inyl linked coumarin-2,3-furocoumarin hybrid 37c was endowed with high selectivity against B. subtilis and E. coli species. The in vitro antibacterial activity of 4с, 29, 37c and 42с can potentially be compared with that of a number of modern antibiotic drugs used in the clinic, suggesting promising prospects for further research. A detailed study of the molecular interactions with the targeted protein MurB was performed using docking simulations and the obtained results are quite promising.

scholarly journals Antibacterial Activity of Tannic Acid and Tannic Acid/Amphiphilic Cationic Polymer Mixtures

2020 ◽  
Vol 32 (6) ◽  
pp. 1491-1496
Author(s):  
Fatimah M. Alzahrani ◽  
Stephen G. Yeates ◽  
Michelle Webb ◽  
Hind Ali Alghamdi
Keyword(s):  
Antibacterial Activity ◽  
Tannic Acid ◽  
Cationic Polymer ◽  
Polymer Mixture ◽  
Klebsiella Pneumonia ◽  
Cationic Polymers ◽  
Polymer Mixtures ◽  
Bacterial Strains ◽  
Gram Positive ◽  
E Coli

In this study, the antibacterial activity of tannic acid/amphiphilic cationic polymer (poly{2-[(methacryloyloxy)ethyl]trimethyl-ammonium chloride}, PMADQUAT) and tannic acid mixtures was examined on the strains of Gram-positive (S. aureus) and Gram-negative (E. coli CI2, E. coli K12, Klebsiella pneumonia and P. aeruginosa) bacteria. Tannic acid exhibited the antibacterial activity against all the studied bacterial strains. The ester linkage between glucose and gallic acid is vital for the antimicrobial activity of tannic acid. Tannic acid inhibited the growth of S. aureus and E. coli K12 (1 wt%) and reduced the growth of P. aeruginosa to 23%. Mixing cationic polymers having different structures (statistical copolymer, homopolymer and diblock polymer) with tannic acid lead to an increase in antibacterial activity of tannic acid and the stability and clarity of mixtures was higher than that of a pure tannic acid solution. Tannic acid/diblock polymer and tannic acid/homopolymer mixtures (0.1 wt%) were excellent for inhibiting the growth of planktonic E. coli K12 bacteria, and a low concentration (0.0001 wt%) of tannic acid/diblock polymer reduced its growth to 19%. By contrast, the tannic acid/statistical polymer mixture (0.0001 wt%) was excellent for inhibiting the growth of Gram-positive S. aureus bacteria.

scholarly journals Photon-Induced Superior Antibacterial Activity of Palladium-Decorated, Magnetically Separable Fe3O4/Pd/mpg-C3N4 Nanocomposites

Molecules ◽  
2019 ◽  
Vol 24 (21) ◽  
pp. 3888 ◽  
Author(s):  
Deepika Thakur ◽  
Qui Thanh Hoai Ta ◽  
Jin-Seo Noh
Keyword(s):  
Antibacterial Activity ◽  
Solution Method ◽  
Pd Nanoparticles ◽  
Bacterial Degradation ◽  
Photoluminescence Intensity ◽  
Bacterial Cells ◽  
Bacterial Strains ◽  
E Coli ◽  
Carrier Recombination ◽  
Solar Light Irradiation

Three-component nanocomposites (Fe3O4/Pd/mpg-C3N4) have been systematically synthesized using a three-step solution method for the photocatalytic bacterial decontamination. The mesoporous g-C3N4 nanosheets (mpg-C3N4), which were prepared by the acid treatment, showed a great improvement in photocatalytic performance. The photoluminescence intensity of the mpg-C3N4 nanosheets was disclosed to drop about 60% from the value of normal g-C3N4 nanosheets. Decoration of mpg-C3N4 with palladium (Pd) nanoparticles led to the effective suppression of carrier recombination and the carrier migration to Fe3O4 nanoparticles. It was revealed that the three-component nanocomposites degraded 99.9% of E. coli and 99.8% of S. aureus bacterial strains within 2 h of solar light irradiation at a 100 μg/mL concentration, demonstrating their superb photocatalytic antibacterial activity. In addition, the nanocomposites could be easily separated from the bacterial cells and repeatedly used for photocatalytic bacterial degradation with good recyclability. The strong photon-induced antibacterial activity and good recyclability of the three-component nanocomposites may represent their potential as a promising antibacterial photocatalyst.

Size-Controlled Synthesis of MgO Nanoparticles and the Assessment of Their Bactericidal Capacity

2013 ◽  
Vol 1547 ◽  
pp. 135-140 ◽  
Author(s):  
Yarilyn Cedeño-Mattei ◽  
Myrna Reyes ◽  
Oscar Perales-Pérez ◽  
Félix R. Román
Keyword(s):  
Average Crystallite Size ◽  
Cost Effective ◽  
Controlled Synthesis ◽  
X Ray Diffraction ◽  
Mgo Nanoparticles ◽  
E Coli ◽  
Mechanism Of Inhibition ◽  
Crystallite Sizes ◽  
Nanoscale Mgo ◽  
Size Controlled

ABSTRACTThe present work focuses on the development of a reproducible and cost-effective size-controlled synthesis route for nanoscale MgO and the preliminary assessment of its bactericide capacity as a function of crystal size. Nanoscale MgO was produced through the thermal decomposition of Mg-carbonate hydrate precursor (hydromagnesite) synthesized in aqueous phase. The exclusive formation of the MgO phase, with an average crystallite size between 7 and 13 ± 1 nm, was evidenced by X-Ray Diffraction and HRTEM analyses. Fourier Transform – Infrared spectroscopy confirmed the evolution of the precursor into the desired MgO structure. The bactericidal tests were conducted by measuring the optical density at 600 nm of E. coli in presence of MgO nanoparticles of specific sizes. MgO nanocrystals with average crystallite sizes of 13nm inhibited bacterial growth up to 35% at 500 mg MgO/L. The mechanism of inhibition could be attributed to the formation of superoxide species on the MgO surface.

scholarly journals ANTIBACTERIAL ACTIVITY OF SOAP MADE FROM ESSENTIAL OILS AND COMMERCIAL SOAP SOLD IN THE LEBANESE MARKET

2021 ◽  
pp. e304
Author(s):  
Candy GERGES ◽  
Mohamad HADLA ◽  
Michele ELIALI ◽  
Martine RICHA ◽  
Nour Mammari ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Essential Oils ◽  
Antibacterial Activities ◽  
Diffusion Method ◽  
Bacterial Strains ◽  
Effective Measure ◽  
E Coli ◽  
Different Types ◽  
Commercial Soap ◽  
Zones Of Inhibition

Background: Thousands of people are dying as a result of infections caused by bacteria. Among the main routes of germ transmission are the hands, making hand hygiene very important in preventing the spread of pathogens and bacterial infection. Hand washing with soap and water is considered to be a simple and effective measure. Old soap manufacturers have long had traditional uses in the Lebanese community. Methods: The purpose of this study is to compare the antibacterial activity of oil-based soaps with commercial soap sold in the Lebanese market. Different types of herbal soap and antiseptics have been used in this study. Four bacterial strains were used: Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli and Enterobacter Spp. The antibacterial activities of these soaps were determined by the diffusion method of disks in agar medium. Results and Discussion: Statistical analysis of zones of inhibition showed that S. epidermidis, P. aeruginosa and Enterobacter Spp. were sensitive only to traditional oil-based soaps, which are Sage, Rose Mary and Cedar. In addition, S. aureus showed sensitivity to soaps comprised of essential oils as well as antibacterial synthetic soap, Dettol and Lifebuoy. On the other hand, E. coli showed resistance to all soaps. Soaps comprised of natural essential oils have shown antibacterial activity superior to so-called “Antibacterial” soaps. Conclusion: Based on this study, we can say that the use of soaps with essential oils might be the best option due to their organic origin as well as their antibacterial proved activities.

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