PITUITARY-GONADAL INTERRELATIONSHIPS IN PUBERTAL FEMALE SUBJECTS

1974 ◽  
Vol 76 (2) ◽  
pp. 214-234 ◽  
Author(s):  
D. A. Adamopoulos ◽  
J. A. Loraine ◽  
S. F. Lunn ◽  
M. A. Mackay ◽  
J. O. Forfar
Keyword(s):  
Sex Characteristics ◽  
First Year ◽  
Adult Women ◽  
Hormonal Activity ◽  
Secondary Sex Characteristics ◽  
Reproductive Life ◽  
Menstruating Women ◽  
Second Year ◽  
Range Of Values ◽  
Female Subjects

ABSTRACT Hormone assays in urine were conducted serially in four girls for 28 to 78 days each year for a period of four or five years. Assays of the three classical oestrogens and pregnanediol were made throughout this time; total gonadotrophins were estimated during the first two years and FSH and/or LH in subsequent years. Oestrogen output rose gradually throughout, evidence of variation in hormonal activity being noted from the second year onwards. In two of the girls who menstruated in the fourth year, the pattern of oestrogen excretion was similar to that of adult women during reproductive life. Pregnanediol output was generally low, tended to rise with increasing age, and from the second year onwards levels fluctuated. Ovulation, as judged by pregnanediol assays, occurred in two out of the nine cycles studied. Total gonadotrophic activity was low in the first year and rose in the second. In the third year FSH output was at the lower end of the range of values occurring in young normally menstruating women and was within this range during the fifth year. LH activity was low when first estimated, rose slightly in the fourth year, and showed a typical adult pattern, including a midcycle peak, in the fifth. The investigation demonstrated a progressive rise in steroid and gonadotrophin output in pubertal female subjects as they increased in stature, developed secondary sex characteristics and approached the menarche; the increase was associated with marked fluctuations in hormonal activity well in advance of the first menstrual bleeding. The physiological significance of these bleedings is discussed, and it is emphasised that the study as a whole provides a useful framework for the investigation of pathological conditions occurring at or about the time of puberty.

Endocrinology of the menopause and hormone replacement therapy

2011 ◽  
pp. 1492-1503
Author(s):  
Henry G. Burger ◽  
Helena J. Teede
Keyword(s):  
Hormone Replacement ◽  
Endocrine Function ◽  
Sex Characteristics ◽  
Pathological State ◽  
Human Ovary ◽  
Secondary Sex Characteristics ◽  
Reproductive Life ◽  
Central Nervous Systems ◽  
Approach Zero ◽  
Oestradiol Production

A major endocrine function of the human ovary is the production of oestradiol, a hormone essential for the development of the secondary sex characteristics, for normal reproduction, and for the integrity of the cardiovascular, skeletal, and central nervous systems in particular. Oestradiol is a product of the granulosa cells, and hence its secretion is dependent largely on the presence of ovarian follicles. The number of those follicles falls steeply in the last 10 years or so of reproductive life (1), to approach zero at around the time of final menses (Fig. 10.1.2.1). This results in a profound decline in oestradiol production, to levels less than 10% of those observed during reproductive life. The question of whether the consequences of this decline are to be regarded as ‘natural,’ or as giving rise to a pathological state of oestrogen deficiency, is a controversial one. This chapter describes the endocrine changes which take place from the mid-reproductive years through to the postmenopausal years, and addresses the consequences of these changes and their possible prevention.

Child, Adolescent, and Adult Development

2014 ◽  
Author(s):  
Jonathan A. Slater ◽  
Katharine A. Stratigos ◽  
Janis L. Cutler
Keyword(s):  
Adult Development ◽  
Middle Childhood ◽  
Risk Taking ◽  
Sex Characteristics ◽  
First Year ◽  
Ego Functions ◽  
Secondary Sex Characteristics ◽  
First Year Of Life ◽  
And Control ◽  
Risk Taking Behaviors

The development of children and adolescents is characterized by abrupt discontinuities as well as continuous aspects of behavior such as individual temperament. The crucial task of the first year of life is the development and solidification of the attachment between infant and caretaker. Toddlers and adolescents tend to experience intense conflicts around autonomy and control that become resolved as they progress in the process of separation-individuation. The tasks of middle childhood include developing a sustained sense of mastery and competence, morality, and stable self-esteem; as ego functions grow and consolidate, children become increasingly able to tolerate frustration and delays in the gratification of their wishes and desires. Adolescence begins with puberty, the period of sexual maturation in which the primary sex organs develop and become capable of reproduction and secondary sex characteristics appear. Although adolescents tend to engage in risk-taking behaviors, the majority of adolescents maintain normal academic and social functioning; an adolescent whose rebelliousness includes severe disturbances in conduct, mood, or drug abuse should be evaluated for possible psychopathology requiring treatment. The main social developmental tasks for adults take place in the realms of work and intimate relationships.

An inevitable crisis? From first to second year in counsellor training

2020 ◽  
Vol 5 (1) ◽  
pp. 74-89
Author(s):  
Hugh Crago
Keyword(s):  
Right Hemisphere ◽  
Training Programme ◽  
First Year ◽  
Training Experience ◽  
Counsellor Training ◽  
Student Dropout ◽  
Second Year ◽  
Neurological Research ◽  
First Year Of Life ◽  
And Control

In a seminal 1973 paper, Robert Clark described the very different “cultures” of the first and second year students in a four year clinical psychology PhD programme. The author applies Clark’s template to his own experiences as trainee or trainer in five different counsellor education programmes, one in the US and four in Australia. Each of the programmes, to varying degrees, demonstrates key features of the pattern identified by Clark, where the first year is “therapeutic” and other-oriented, the second is “professional” and self-focused. The author concludes that all the surveyed programmes exhibited some level of “second year crisis”, in which a significant number of students felt abandoned, dissatisfied, or rebellious. The author extends and refines Clark’s developmental analogy (first year = childhood; second year = adolescence) to reflect recent neurological research, in particular, the shift from a right hemisphere-dominant first year of life, prioritising affiliative needs, to a left hemisphere-dominant second year, prioritising autonomy and control. This shift is paralleled later by a more gradual move from a protective, supportive childhood to necessary, but sometimes conflictual, individuation in adolescence. The first two years of a counsellor training programme broadly echo this process, a process exacerbated by the second year internship/placement, in which students must “leave home” and adjust to unfamiliar, potentially less nurturing, authority figures. Finally, the author suggests introducing more rigorous “academic holding” into the first year, and greater attention to “therapeutic holding” of dissident students in the second, hopefully decreasing student dropout, and achieving a better balanced training experience.

Implementation of the Second-year course in an Engineering Professional Spine

2018 ◽  
Author(s):  
Umar Iqbal ◽  
Deena Salem ◽  
David Strong
Keyword(s):  
Learning Outcomes ◽  
Research University ◽  
Engineering Students ◽  
Employability Skills ◽  
First Year ◽  
Computer Engineering ◽  
Core Courses ◽  
Second Year ◽  
First Time ◽  
Academic Year

The objective of this paper is to document the experience of developing and implementing a second-year course in an engineering professional spine that was developed in a first-tier research university and relies on project-based core courses. The main objective of this spine is to develop the students’ cognitive and employability skills that will allow them to stand out from the crowd of other engineering graduates.The spine was developed and delivered for the first time in the academic year 2010-2011 for first-year general engineering students. In the year 2011-2012, those students joined different programs, and accordingly the second-year course was tailored to align with the different programs’ learning outcomes. This paper discusses the development and implementation of the course in the Electrical and Computer Engineering (ECE) department.

Exploring the Implementation of Early Math Assessments in Kindergarten Classrooms: A Research-Practice Collaboration

2020 ◽  
Author(s):  
Jennifer McDonald ◽  
Rebecca Merkley ◽  
Jacqueline Mickle ◽  
Lisa Collimore ◽  
Daniel Ansari
Keyword(s):  
Mathematical Thinking ◽  
Math Education ◽  
Kindergarten Students ◽  
First Year ◽  
Research Practice ◽  
Early Numeracy ◽  
Future Directions ◽  
Collaborative Project ◽  
Practice Gap ◽  
Second Year

Research in cognitive development has highlighted that early numeracy skills are associated with later math achievement, suggesting that these skills should be targeted in early math education. Here we tested whether tools used by researchers to assess mathematical thinking could be useful in the classroom. This paper describes a collaborative project between cognitive scientists and school board researchers/educators implementing numeracy screeners with kindergarten students over the course of three school years. The Give-A-Number task (Wynn, 1990) was used with first-year kindergarten students and the Numeracy Screener [BLINDED] with second-year kindergarten students. Results indicated that educators (N = 59) found the tools feasible to implement and helpful for exploring their students’ thinking and targeting instruction. The Educators’ feedback also helped inform improvements to the implementation of the tools and future directions for both the schools and the researchers. This work emphasizes the importance of transdisciplinary collaboration to address the research-practice gap.

Influence of abiotic factors and hosts on seasonal dynamic of green lacewing, Chrysoperla carnea (Stephens)

2016 ◽  
Vol 3 (3) ◽  
Author(s):  
ARVIND KUMAR ◽  
POOJA KHULBE
Keyword(s):  
Abiotic Factors ◽  
Host Population ◽  
Maximum Temperature ◽  
First Year ◽  
Green Lacewing ◽  
Larval Population ◽  
Correlation Studies ◽  
Helianthus Annus ◽  
Sunflower Crop ◽  
Second Year

Influence of abiotic factors and hosts on population dynamics of green lacewing, Chrysoper lacarnea (Stephens) was studied in sunflower, Helianthus annus (Linn.).The maximum number of C. carnea population was found during mid March –mid April in the first year and mid April – mid May in the second year in sunflower crop. The maximum number of host population viz. egg and larva of Helicoverpa armigera and Myzuspe rsicae population were found during mid March –mid April in both the year and correlation studies revealed the positive and significant correlation between larval population of H. armigera, M. persicae and predator C. carnea. While there was no significant relationship found between eggs of H. armigera and C. carnea. The C. carnea population on H. annus during both the year was positively correlated with maximum temperature and found significant,while negatively correlated with relative humidity.However, no significant correlation of C. carnea was found with minimum temperature in both the year.

Effects of Cutting First Year Red Clover on Stand and Yield in the Second Year 1

1955 ◽  
Vol 47 (5) ◽  
pp. 224-228 ◽  
Author(s):  
James H. Torrie ◽  
Earle W. Hanson
Keyword(s):  
Red Clover ◽  
First Year ◽  
Second Year

scholarly journals Socio-economic consequences of mental distress: quantifying the impact of self-reported mental distress on the days of incapacity to work and medical costs in a two-year period: a longitudinal study in Germany

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Gerhard Müller ◽  
Manuela Bombana ◽  
Monika Heinzel-Gutenbrenner ◽  
Nikolaus Kleindienst ◽  
Martin Bohus ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Mental Distress ◽  
Linear Models ◽  
Longitudinal Research ◽  
Depression Scale ◽  
Routine Data ◽  
Medical Costs ◽  
First Year ◽  
Second Year ◽  
The Impact

Abstract Background Mental disorders are related to high individual suffering and significant socio-economic burdens. However, it remains unclear to what extent self-reported mental distress is related to individuals’ days of incapacity to work and their medical costs. This study aims to investigate the impact of self-reported mental distress for specific and non-specific days of incapacity to work and specific and non-specific medical costs over a two-year span. Method Within a longitudinal research design, 2287 study participants’ mental distress was assessed using the Hospital Anxiety and Depression Scale (HADS). HADS scores were included as predictors in generalized linear models with a Tweedie distribution with log link function to predict participants’ days of incapacity to work and medical costs retrieved from their health insurance routine data during the following two-year period. Results Current mental distress was found to be significantly related to the number of specific days absent from work and medical costs. Compared to participants classified as no cases by the HADS (2.6 days), severe case participants showed 27.3-times as many specific days of incapacity to work in the first year (72 days) and 10.3-times as many days in the second year (44 days), and resulted in 11.4-times more medical costs in the first year (2272 EUR) and 6.2-times more in the second year (1319 EUR). The relationship of mental distress to non-specific days of incapacity to work and non-specific medical costs was also significant, but mainly driven from specific absent days and specific medical costs. Our results also indicate that the prevalence of presenteeism is considerably high: 42% of individuals continued to go to work despite severe mental distress. Conclusions Our results show that self-reported mental distress, assessed by the HADS, is highly related to the days of incapacity to work and medical costs in the two-year period. Reducing mental distress by improving preventive structures for at-risk populations and increasing access to evidence-based treatments for individuals with mental disorders might, therefore, pay for itself and could help to reduce public costs.

scholarly journals Field Efficacy of Steinernema sp. (Rhabditida: Steinernematidae) on the Colorado Potato Beetle Overwintering Generation

Plants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1464
Author(s):  
Maja Čačija ◽  
Renata Bažok ◽  
Majda Kolenc ◽  
Tena Bujas ◽  
Zrinka Drmić ◽  
...  
Keyword(s):  
Colorado Potato Beetle ◽  
First Generation ◽  
Control Measures ◽  
Recommended Dose ◽  
Steinernema Feltiae ◽  
First Year ◽  
Potato Beetle ◽  
Field Efficacy ◽  
Second Year ◽  
Economic Pest

Colorado potato beetle (CPB) is an economic pest of potato that has developed resistance to all classes of chemical insecticides, thus requiring alternative control measures. As a potential solution, entomopathogenic nematodes (EPNs) have proven effective in suppressing this pest, but their efficacy against overwintering generations of CPB in Croatia has not been sufficiently researched. The aim of this two-year (2018–2019) field study was to determine the efficacy of Steinernema feltiae and Steinernema carpocapsae applied to overwintering CPB adults. EPNs were applied at three doses (7.5 mil./10 m2, 5.0 mil./10 m2 (the recommended dose) and 2.5 mil./10 m2) by watering the soil where the adults were overwintering. The first-year results were satisfactory for both EPNs: the efficacy of S. feltiae ranged from 79.03% to 100.00%, while the efficacy of S. carpocapsae ranged from 77.32% to 96.22%. In the second year, the highest efficacy (69.57%) was obtained using the recommended dose of S. feltiae. Although the results are not consistent across the two years of our study and suggest further research, they indicate that EPNs have great potential in controlling overwintering CPB generations to reduce first generation abundance and damage, and also to prevent the spread of new generations to surrounding potato growing areas.

scholarly journals Sperm Cryopreservation in American Flamingo (Phoenicopterus Ruber): Influence of Cryoprotectants and Seminal Plasma Removal

Animals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 203
Author(s):  
María Gemma Millán de la Blanca ◽  
Eva Martínez-Nevado ◽  
Cristina Castaño ◽  
Juncal García ◽  
Berenice Bernal ◽  
...  
Keyword(s):  
Seminal Plasma ◽  
Genetic Material ◽  
First Year ◽  
Sperm Cryopreservation ◽  
Straight Line ◽  
The Family ◽  
Second Year ◽  
American Flamingo ◽  
Phoenicopterus Ruber

The American flamingo is a useful model for the development of successful semen cryopreservation procedures to be applied to threatened related species from the family Phoenicopteridae, and to permit genetic material banking. Current study sought to develop effective sperm cryopreservation protocols through examining the influences of two permeating cryoprotectants and the seminal plasma removal. During two consecutive years (April), semen samples were collected and frozen from American flamingos. In the first year, the effect of two permeating cryoprotectants, DMA (dimethylacetamide) (6%) or Me2SO (dimethylsulphoxide) (8%), on frozen–thawed sperm variables were compared in 21 males. No differences were seen between DMA and Me2SO for sperm motility, sperm viability, and DNA fragmentation after thawing. In the second year, the role of seminal plasma on sperm cryoresistance was investigated in 31 flamingos. Sperm samples were cryopreserved with and without seminal plasma, using Me2SO (8%) as a cryoprotectant. The results showed that samples with seminal plasma had higher values than samples without seminal plasma for the following sperm variables: Straight line velocity (22.40 µm/s vs. 16.64 µm/s), wobble (75.83% vs. 69.40%), (p < 0.05), linearity (62.73% vs. 52.01%) and straightness (82.38% vs. 73.79%) (p < 0.01); but acrosome integrity was lower (55.56% vs. 66.88%) (p < 0.05). The cryoresistance ratio (CR) was greater in samples frozen with seminal plasma than without seminal plasma for CR-progressive motility (138.72 vs. 54.59), CR-curvilinear velocity (105.98 vs. 89.32), CR-straight line velocity (152.77 vs. 112.58), CR-average path velocity (122.48 vs. 98.12), CR-wobble (111.75 vs. 102.04) (p < 0.05), CR-linearity (139.41 vs. 113.18), and CR-straightness (124.02 vs. 109.97) (p < 0.01). This research demonstrated that there were not differences between Me2SO and DMA to successful freezing sperm of flamingos; seminal plasma removal did not provide a benefit for sperm cryopreservation.

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