scholarly journals Free thyroxine is an independent predictor of subcutaneous fat in euthyroid individuals

2009 ◽  
Vol 161 (3) ◽  
pp. 459-465 ◽  
Author(s):  
Maria Alevizaki ◽  
Katerina Saltiki ◽  
Paraskevi Voidonikola ◽  
Emily Mantzou ◽  
Christos Papamichael ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Subcutaneous Fat ◽  
Cross Sectional Study ◽  
Free Thyroxine ◽  
Hip Circumference ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Regional Adiposity ◽  
Tsh Levels ◽  
Apparently Healthy

ObjectiveThyroid function parameters have been associated with obesity, but associations with the type of adiposity have not been examined. We used ultrasound (US) to assess regional adiposity and investigated associations of thyroid function with parameters of central obesity.DesignCross-sectional study.MethodsA total of 303 apparently healthy individuals (age 42.9±8.8, body mass index (BMI) 19.0–43.3, median 26.2 kg/m2, 181 women) were examined for indices of the metabolic syndrome. BMI, waist and hip circumference, abdominal subcutaneous fat (SF), and preperitoneal fat (PF) layer was estimated. TSH, free thyroxine (fT4), triiodothyronine (T3), thyroid autoantibodies, insulin, glucose, and lipid levels were measured. Subjects receiving T4(9.2%) were excluded.ResultsSF and SF/PF ratio were inversely correlated with fT4levels (r=−0.169,P=0.023,r=−0.193,P=0.009 respectively). In multivariate analysis, fT4was a predictor of SF and SF/PF, independently of age, sex, and smoking. SF correlated with TSH levels (r=0.149,P=0.037). PF and SF were positively associated with T3levels (r=0.245,P=0.004 andr=0.189,P=0.019 respectively). T3levels were positively associated with BMI (r=0.257,P=0.0004), waist perimeter (r=0.324,P<0.0001), and waist-to-hip ratio (WHR;r=0.363,P<0.0001). The T3/fT4ratio was positively correlated with SF (r=0.182,P=0.028), WHR (r=0.267,P=0.0003), and BMI (r=0.146,P=0.043).ConclusionsIncreasing SF accumulation as assessed by US is associated with lower fT4and higher TSH levels among euthyroid slightly overweight individuals. These associations indicate that subtle variation in thyroid function may participate in regional adiposity.

scholarly journals Iodine status and thyroid function among Spanish schoolchildren aged 6–7 years: the Tirokid study

2016 ◽  
Vol 115 (9) ◽  
pp. 1623-1631 ◽  
Author(s):  
L. Vila ◽  
S. Donnay ◽  
J. Arena ◽  
J. J. Arrizabalaga ◽  
J. Pineda ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Reference Values ◽  
Thyroid Autoimmunity ◽  
Geographical Area ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
Cross Sectional ◽  
History Of ◽  
Tsh Levels

AbstractI deficiency is still a worldwide public health problem, with children being especially vulnerable. No nationwide study had been conducted to assess the I status of Spanish children, and thus an observational, multicentre and cross-sectional study was conducted in Spain to assess the I status and thyroid function in schoolchildren aged 6–7 years. The median urinary I (UI) and thyroid-stimulating hormone (TSH) levels in whole blood were used to assess the I status and thyroid function, respectively. A FFQ was used to determine the consumption of I-rich foods. A total of 1981 schoolchildren (52 % male) were included. The median UI was 173 μg/l, and 17·9 % of children showed UI<100 μg/l. The median UI was higher in males (180·8 v. 153·6 μg/l; P<0·001). Iodised salt (IS) intake at home was 69·8 %. IS consumption and intakes of ≥2 glasses of milk or 1 cup of yogurt/d were associated with significantly higher median UI. Median TSH was 0·90 mU/l and was higher in females (0·98 v. 0·83; P<0·001). In total, 0·5 % of children had known hypothyroidism (derived from the questionnaire) and 7·6 % had TSH levels above reference values. Median TSH was higher in schoolchildren with family history of hypothyroidism. I intake was adequate in Spanish schoolchildren. However, no correlation was found between TSH and median UI in any geographical area. The prevalence of TSH above reference values was high and its association with thyroid autoimmunity should be determined. Further assessment of thyroid autoimmunity in Spanish schoolchildren is desirable.

Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome

2019 ◽  
pp. 68-73
Author(s):  
Trong Nghia Nguyen ◽  
Thi Nhan Nguyen ◽  
Thi Dua Dao
Keyword(s):  
Metabolic Syndrome ◽  
Medical Center ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
The Metabolic Syndrome ◽  
25 Hydroxyvitamin D ◽  
Key Words Metabolic Syndrome ◽  
And Control

Background: The metabolic syndrome is a constellation of cardiometabolic risk factors that tend to cluster together in affected individuals more often than predicted by chance. The presence of the metabolic syndrome substantially increases the risk of developing type 2 diabetes and cardiovascular disease, and is associated with a range of adverse clinical outcomes, many of which are closely associated with aging. Current estimates suggest that approximately 20 - 25% of the world’s population is affected by the metabolic syndrome. The prevalence of the metabolic syndrome rises with age and more than 45% of people aged over 60 years have the metabolic syndrome. Recent studies show that low vitamin D status is very common in the world and this is a risk factor of metabolic syndrome. Objective: (1) Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome. (2) Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Material and method: A cross-sectional study with control group on 318 adult subjects for health examinations at International Medical Center at Hue Central Hospital, including 139 subjects with metabolic syndrome and control group of 179 healthy subjects. Metabolic syndrome was defined according to the IDF, NHLBI, AHA, WHF, IAS, IASO (2009). Plasma hydroxyvitamin D concentration was measured using chemiluminescent microparticle immunoassay. Reciever operating characteristic (ROC) curve were generated to assess sensitivity and specificity for different cut off value of 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Results: Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome was 26.4 ng/ml, incidence of plasma 25-hydroxyvitamin D deficiency (59.7%) was significantly higher than in control group (23.5%) (p < 0.001). The optimal cut off point for 25-OH-D concentration for predictor of metabolic syndrome as 26.4 ng/ml (AUC=0.657, sensitivity=53.4%, specificity=71.6%). Conclusion: In 139 subjects with metabolic syndrome, the plasma 25-hydroxyvitamin D concentration was 26.4 ng/ml and the incidence of 25-hydroxyvitamin D deficiency in the metabolic syndrome group was 59.7%. The optimal cut off point for plasma 25-hydroxyvitamin D concentration for predictor of metabolic syndrome as 26.4 ng/ml. Key words: Metabolic syndrome, 25-hydroxyvitamin D

scholarly journals High Adherence to the Mediterranean Diet Is Associated with a Reduced Risk of Obesity among Adults in Gulf Countries

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 995
Author(s):  
Israa M. Shatwan ◽  
Eiman A. Alhinai ◽  
Balqees Alawadhi ◽  
Shelini Surendran ◽  
Najlaa M. Aljefree ◽  
...  
Keyword(s):  
Mediterranean Diet ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Inverse Association ◽  
Protective Effects ◽  
Hip Circumference ◽  
Cross Sectional ◽  
Gulf Countries ◽  
The Mean ◽  
The Mediterranean

The Mediterranean diet (MedDiet) is considered as a good example of a healthy dietary pattern that has protective effects on obesity. The aim of the present study was to assess the adherence of adults from three Gulf countries (Saudi Arabia, Oman, and Kuwait) to the MedDiet and its association with obesity risk. A cross-sectional study was conducted on 961 men and women (75.7%) aged 20–55 years old. Waist circumference (WC), and hip circumference (HC) were measured waist/hip ratio (WHR) and body mass index (BMI) were calculated. A validated 14-item Questionnaire was used to measure adherence to MedDiet. The mean of the adherence to MedDiet score was 5.9 ± 2.03 for the total sample. An inverse association was observed between the adherence to MedDiet and BMI after adjusting for potential confounders (p = 0.0003 in total participants, and p = 0.001 in women only). A protective effect was seen with a higher adherence to the MedDiet on HC, suggesting that a greater adherence to the MedDiet was associated with a decreased HC (p = 0.04 in total participants, and p = 0.01 in women only). In conclusion, low adherence to the MedDiet among participants from three gulf countries was associated with increased obesity indicators, BMI, and HC.

scholarly journals Reproducibility and agreement between three positions for handgrip assessment

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Olga-Cecilia Vargas-Pinilla ◽  
Eliana-Isabel Rodríguez-Grande
Keyword(s):  
Supine Position ◽  
Cross Sectional Study ◽  
Sitting Position ◽  
Average Difference ◽  
Cross Sectional ◽  
Hand Grip ◽  
Standardization Process ◽  
The One ◽  
Level Of Agreement ◽  
Apparently Healthy

AbstractThe protocol established for taking hand grip dynamometry measurements determines that the patient must be in a sitting position. This protocol cannot be applied due to the patient’s conditions in some cases, such as abdominal surgery, musculoskeletal spine or hip injuries. The purpose was to determine the reproducibility and level of agreement between the Handgrip dynamometry in supine position with the elbow flexed or extended, and the one measured in the sitting position, the design was a descriptive cross-sectional study. The population were young apparently healthy between 18 and 30 years of age (N = 201). Handgrip measurement was performed on both upper limbs in a sitting position with a flexed elbow, a supine position with a flexed elbow, and supine position with the elbow extended. Reproducibility was nearly perfect in all positions (ICC 0.95–0.97). Regarding the level of agreement for the comparison between sitting and supine positions with a flexed elbow, an average difference of − 0.406. For supine position with an extended elbow and supine position with a flexed elbow, the average difference was − 1.479. Considering the results, clinicians or researchers can choose any of the positions evaluated herein and obtain reliable results as long as the standardization process is followed.

A Cross-Sectional Study of Socioeconomic Status and the Metabolic Syndrome in Korean Adults

2007 ◽  
Vol 17 (4) ◽  
pp. 320-326 ◽  
Author(s):  
Min Jung Park ◽  
Kyung Eun Yun ◽  
Go Eun Lee ◽  
Hong Jun Cho ◽  
Hye Soon Park
Keyword(s):  
Metabolic Syndrome ◽  
Socioeconomic Status ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Korean Adults ◽  
The Metabolic Syndrome

The association between meat consumption and the metabolic syndrome: a cross-sectional study and meta-analysis

2021 ◽  
pp. 1-15
Author(s):  
Khemayanto Hidayat ◽  
Wan-Zhan Zhu ◽  
Si-Min Peng ◽  
Jin-Jin Ren ◽  
Meng-Lan Lu ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Fish Consumption ◽  
Meta Analysis ◽  
Meat Consumption ◽  
Cross Sectional Study ◽  
Red Meat ◽  
Inverse Association ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Metabolic Syndrome

Abstract The findings regarding the associations between red meat, fish and poultry consumption, and the metabolic syndrome (Mets) have been inconclusive, and evidence from Chinese populations is scarce. A cross-sectional study was performed to investigate the associations between red meat, fish and poultry consumption, and the prevalence of the Mets and its components among the residents of Suzhou Industrial Park, Suzhou, China. A total of 4424 participants were eligible for the analysis. A logistic regression model was used to estimate the OR and 95 % CI for the prevalence of the Mets and its components according to red meat, fish and poultry consumption. In addition, the data of our cross-sectional study were meta-analysed under a random effects model along with those of published observational studies to generate the summary relative risks (RR) of the associations between the highest v. lowest categories of red meat, fish and poultry consumption and the Mets and its components. In the cross-sectional study, the multivariable-adjusted OR for the highest v. lowest quartiles of consumption was 1·23 (95 % CI 1·02, 1·48) for red meat, 0·83 (95 % CI 0·72, 0·97) for fish and 0·93 (95 % CI 0·74, 1·18) for poultry. In the meta-analysis, the pooled RR for the highest v. lowest categories of consumption was 1·20 (95 % CI 1·06, 1·35) for red meat, 0·88 (95 % CI 0·81, 0·96) for fish and 0·97 (95 % CI 0·85, 1·10) for poultry. The findings of both cross-sectional studies and meta-analyses indicated that the association between fish consumption and the Mets may be partly driven by the inverse association of fish consumption with elevated TAG and reduced HDL-cholesterol and, to a lesser extent, fasting plasma glucose. No clear pattern of associations was observed between red meat or poultry consumption and the components of the Mets. The current findings add weight to the evidence that the Mets may be positively associated with red meat consumption, inversely associated with fish consumption and neutrally associated with poultry consumption.

scholarly journals Echocardiographic assessment of suspicious clinical and electrocardiogram findings of healthy young male military aspirants: a cross sectional observational study

2018 ◽  
Vol 14 (2) ◽  
pp. 92-97
Author(s):  
Navaraj Paudel ◽  
Vijay Madhav Alurkar
Keyword(s):  
Physical Examination ◽  
Sinus Bradycardia ◽  
Pulmonary Stenosis ◽  
Young Male ◽  
Physical Exertion ◽  
Cross Sectional Study ◽  
Structural Abnormality ◽  
Cross Sectional ◽  
Structural Abnormalities ◽  
Apparently Healthy

ABSTRACTBackground: Heavy exercise is associated with multiple physiological changes in cardiovascular system. Individuals who otherwise are healthy and asymptomatic are also found to have cardiac abnormalities. The aim of study is to find prevalance of structural abnormalities in apparently healthy males who are found to have abnormal/ suspicious clinical/electrogram findings during routine screening. Materials and Methods:A cross-sectional study was done in the department of cardiology within Manipal Teaching Hospital, Pokhara over a period of 3 years (December 2013 to December 2016). The study population included all the participants who were apparently healthy young males competing for military recruitment. After the initial screening, those who had abnormal/suspicious findings in the physical examination or in ECG were subjected for trans-thoracic echocardiogram to assess for any structural abnormality Results: Out of 1950 individuals, who underwent physical examination and ECG, 165 had abnormal physical findings and 261 had abnormal ECG findings (21.84% of total had any form of abnormality). 72 (43%) had grade 2 short systolic murmur in the pulmonary area followed by pansystolic murmur in apex. Only 1.8% had diastolic murmur in aortic area. Most common ECG abnormality found was LVH followed by sinus bradycardia and Tinversion in III . Almost 7% of individuals with abnormal ECG findings. Only 16 (0.82% of the total screened/ 4.38% of suspicious findings) had structural abnormalities in echocardiography: 12 had RHD (MR-7, AR-3, R+AS+MR=2); 1 had ASD, 1 had VSD, 1 had Ebstein’s anomaly and 1 had mild valvular pulmonary stenosis (congenital). Conclusion: Individuals who are otherwise healthy and asymptomatic were found to have cardiac abnormality (almost 1.7% had serious electrical or structural abnormality). Cardiovascular screening of all the individuals seeking jobs requiring intense physical exertion is essential to prevent serious cardiovascular outcomes.Keywords: echocardiography; electrocardiography; intense exercise; physical cardiac findings.

scholarly journals Thyroid Function and Ultrasonography Abnormalities in Lithium-Treated Bipolar Patients: A Cross-sectional Study with Healthy Controls

2017 ◽  
Vol 54 (2) ◽  
pp. 108-115 ◽  
Author(s):  
Ozlem KUMAN TUNCEL ◽  
Fisun AKDENIZ ◽  
Suha Sureyya OZBEK ◽  
Gulgun KAVUKCU ◽  
Gokcen UNAL KOCABAS
Keyword(s):  
Thyroid Function ◽  
Cross Sectional Study ◽  
Healthy Controls ◽  
Sectional Study ◽  
Cross Sectional ◽  
Bipolar Patients
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