IS THERE A "RIGHT" OF PARENTHOOD?

PEDIATRICS ◽  
1994 ◽  
Vol 93 (4) ◽  
pp. 646-646

A woman was enraged (recently) because her health insurance company, after paying for two unsuccessful attempts at in vitro fertilization, had refused to reimburse her for further infertility treatments. "They're depriving me of my right to become a mother," she said, "and I'm going to sue them." But where is it written that our society owes everyone the "right" to become a parent, regardless of the financial or ethical cost?... Almost no one has questioned the notion of parenthood as a right and infertility as a disaster that must be fought with all the high-tech tools of modern medicine . . . but when infertility is viewed simply as one misfortune on a scale of sorrows—less horrible, say, than mind destroying diseases or mass starvation—the ethical balance looks quite different.

2021 ◽  
Author(s):  
Itay Erlich ◽  
Assaf Ben-Meir ◽  
Iris Har-Vardi ◽  
James A Grifo ◽  
Assaf Zaritsky

Automated live embryo imaging has transformed in-vitro fertilization (IVF) into a data-intensive field. Unlike clinicians who rank embryos from the same IVF cycle cohort based on the embryos visual quality and determine how many embryos to transfer based on clinical factors, machine learning solutions usually combine these steps by optimizing for implantation prediction and using the same model for ranking the embryos within a cohort. Here we establish that this strategy can lead to sub-optimal selection of embryos. We reveal that despite enhancing implantation prediction, inclusion of clinical properties hampers ranking. Moreover, we find that ambiguous labels of failed implantations, due to either low quality embryos or poor clinical factors, confound both the optimal ranking and even implantation prediction. To overcome these limitations, we propose conceptual and practical steps to enhance machine-learning driven IVF solutions. These consist of separating the optimizing of implantation from ranking by focusing on visual properties for ranking, and reducing label ambiguity.


2018 ◽  
Vol 1 (102) ◽  
pp. 47
Author(s):  
Ángel José Gómez Montoro

Resumen:El presente trabajo es un análisis de cómo ha evolucionado la protección del no nacido en España desde la aprobación de la Constitución de 1978. Se centra, en particular en el estudio de la legislación y de la jurisprudencia constitucional sobre dos temas especialmente relevantes y controvertidos: la regulación del aborto, de un lado, y de la fecundación in vitro y uso de embriones, sus tejidos y órganos, de otro. Tanto el legislador como la doctrina del Tribunal Constitucional se han inclinado por una protección gradualista de la vida humana en formación que deja abiertos muchos interrogantes desde la perspectiva del derecho a la vida (art. 15 CE) y la dignidad humana (art. 10.1 CE)Summary:1. The Introduction Of Abortion In Spain And The STC 53/1985: a) From Criminalization To Decriminalization In Certain Circumstances; b) STC 53/1985: i) Right To Life And Prenatal Life; ii) The Life Of The Unborn As A Constitutional Interest; iii) The Constitutionality Of The Indication System; iv) The Conditions For The Constitutionality Of Decriminalization; c) The New Regulation. 2. From The «Indication System» To The «System Of Deadlines»: Organic Law 2/2010 Of 3 March On Sexual And Reproductive Health And Voluntary Termination Of Pregnancy: a) The Evolution Of Abortion In Spain Under The 1985 Act;b) The Arguments For The Reform And The Context Of The New Regulation;c) The New Regulation. 3. An Open Debate: a) The Conditions For The Constitutionality Of Decriminalization; b) The Failed Reform Of The Act. 4. The Weak Protection Of The Embryo In The Legislation On In Vitro Fertilization And The Use Of Embryonic Organs And Tissues, And The SSTC 212/1996 And 116/1999: a) Act 35/1988 On Assisted Reproduction Techniques, And Act 42/1988 On Donation And Use Of Human Embryos And Fetuses And Their Cells, Tissues And Organs; b) Negation Of The Right To Life Of The Embryo And Consequences For Its Consideration As A Constitutionally Protected Legal Interest: i) The Embryo Does Not Hold The Right To Life; ii) Two New Categories:Pre-Embryos And Non-Viable Embryos And Their Legal Relevance; iii) Surplus Embryos; iv) The Absence Of Any Criminal Protection; v) A Weak Concept Of Dignity. 5. Legislative Evolution; 6. A Model For The Gradual (Dis)Protection Of Unborn Human Life.Abstract:This paper analyzes the evolution of the protection of the unborn human life in Spain since the enactment of the 1978 Constitution. It focuses, in particular, on the study of the laws and the constitutional jurisprudence on two relevant matters: the regulation of abortion; and the in vitro fertilization, the use of embryos their tissues and organs. The legislator and the decisions of the Constitutional Court have opted for gradualist protection of the embryo that leaves many questions open from the perspective of the right to life (Article 15 SC) and human dignity (Article 10.1 SC).


2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S51-S52
Author(s):  
Arati Inamdar ◽  
Abraham Loo

Abstract The risk of ovarian malignancy is rare in pregnancy with a reported incidence of approximately 1 in 50,000. Ovarian clear cell carcinoma (OCCC) accounts for 5% to 10% of all ovarian carcinomas with mean age of 50 to 55 years and is often associated with endometriosis. We present a case of 38-year-old G2P1 Asian female with an in vitro fertilization pregnancy and history of endometriosis who presented with the right adnexal mass. The transvaginal ultrasound performed during the early pregnancy was suggestive of endometrioma or desmoid tumor. At 32 weeks, the patient presented to the emergency department with preeclampsia and severe headache. An emergency cesarean section was performed due to worsening of the patient’s condition. An ovarian mass arising from the right ovary and with a friable and hemorrhagic internal surface was excised, which weighed 63 g and measured 14.0 × 10.5 × 3.0 cm. Its external surface was smooth, hemorrhagic, but without any excrescences. The serial sectioning revealed multiple cystic lesions filled with necrotic material overall occupying 80% of the mass. Microscopically, the viable ovarian tissue demonstrated tubulocystic/papillary architecture lined by hyperchromatic hobnail cells along with focal areas of solid sheets of tumor cells displaying clear cytoplasm. Immunohistochemical stains for Wilm’s tumor 1 and p53 were negative while positive for PAX8. These findings were indicative of OCCC without overexpression of wild-type p53. The PET scan performed few weeks after delivery showed widespread metastasis. We present a unique case of metastatic OCCC removed at the time of cesarean section in the late-preterm period. Our case not only emphasizes the need for definitive treatment option for endometriosis but also a close imaging surveillance of all masses diagnosed during pregnancy in women with risk factors such as endometriosis and Asian ethnicity. Furthermore, our study advocates the need for possible guidelines for management of such rare cases.


2021 ◽  
Vol 22 (2) ◽  
pp. 55-59
Author(s):  
Yu. S. Chekhova ◽  
◽  
S. V. Soloveva ◽  
M. V. Antonova ◽  
O. A. Lyubimceva ◽  
...  

Predicting the onset of pregnancy by in vitro fertilization (IVF) in women with tuboperitoneal infertility is a pressing challenge of modern medicine. Aim: to develop a method for determining the chance of pregnancy by IVF in women with tuboperitoneal infertility, based on the analysis of physiological parameters, using the binary logistic regression. Materials and methods. The object of the study is clinically healthy women before pregnancy and in the first trimester after conception, women with tuboperitoneal infertility before entering the IVF and in the first trimester of gestation, and women with tuboperitoneal infertility and an unsuccessful IVF trial. We analyzed the state of the cardiovascular system and autonomic regulation, adaptive capabilities and height-weight indicators at the first stage of the study. The data were statistically processed using the Microsoft Office and Statistica10 software package. We used the binary logistic regression method to create a model for predicting pregnancy in the second stage. Results. Based on the physiological indicators obtained using logistic regression analysis a mathematical model was built – a formula for assessing the probability of non-pregnancy. Conclusion. The quality of prognosis of the binary logistic regression model was 97.2%. The model can serve as a method for predicting the onset of pregnancy by IVF in women with tuboperitoneal infertility. We recommend this method for use in the work of a practicing physician.


2019 ◽  
Vol 35 (6) ◽  
pp. 485-489 ◽  
Author(s):  
Claudia Massarotti ◽  
Giulia Gentile ◽  
Chiara Ferreccio ◽  
Paola Scaruffi ◽  
Valentino Remorgida ◽  
...  

2020 ◽  
Vol 18 (1) ◽  
pp. 59-66
Author(s):  
Nguyen Huu Duc ◽  
Pham Thu Giang ◽  
Tran Thi Binh Nguyen ◽  
Bui Dai Phong

The objective of this study was to determine the right conditions for the separation of Blanc-Blue-Belge bovine sperm (BBB) by swim-up mothed; determine the maturity of hybrid Zebu bovine eggs; and culture of embryos after in vitro fertilization. After 60-80 minutes of swim-up in CAP-05, BBB bovine sperms were healthy, straight movement and separated with a concentration of 106 sperm/ml. Hybrid Zebu bovine eggs developed and matured in the maturation medium with the basic medium TCM-199 supplemented with 10% calf serum, FSH (0.75 µg / ml), LH (0.15 µg / ml) and Estradiol (2.5 µg / ml), the results showed that the IVM-08 medium had significantly higher maturation rates than IVM-03, the proportion of mature eggs reached 71,11% compared to 51.69%, respectively (P <0.01). In vitro fertilization of hybrid Zebu bovine egg in IVF-08 medium. In vitro fertilized embryos (BBB x hybrid Zebu) developed from bovine sperms separated by the swim-up method achieved a better rate of morula-blastocysts in IVC-09 than IVC-06 medium, 21.68% compared to 8.56%, respectively (P <0.01). The conclusion was that the suitable conditions for BBB bovine sperm separation and in vitro embryo production (BBB x hybrid Zebu) were determined. This is the premise to create bovine semen, BBB bovine embryos with defined gender.


2012 ◽  
Vol 61 (3) ◽  
Author(s):  
Marina Casini ◽  
Carlo Casini ◽  
Rafael Santamaria D'Angelo ◽  
Joseph Meaney ◽  
Nikolas Nikas ◽  
...  

Il contributo esamina il “Caso n. 12.361 Gretel Artavia Urilla et Al. vs. Costa Rica” sul quale si attende una pronuncia della Corte interamericana dei diritti umani. La vicenda ha origine dalla sentenza della Corte costituzionale costaricana (del 15 marzo 2000 n. 2000-02306) che aveva annullato, per ragioni di forma e di sostanza, il Decreto Ejecutivo n. 24029-S1 (del 3 febbraio 1995) sulla procreazione artificiale umana. La vicenda prosegue davanti alla Commissione interamericana chiamata in causa da una “Petición” che accusa la Repubblica del Costa Rica di aver violato i diritti di alcune coppie in attesa di realizzare il loro “progetto parentale”. Il divieto di fecondazione artificiale confliggerebbe, in sintesi, con il diritto alla privacy e alla vita familiare, con il diritto di fondare una famiglia con il principio di uguaglianza contenuti nella Convenzione americana dei diritti umani (“Patto di San Josè”). Al termine di un lungo percorso e di un ampio dibattito, la Commissione ha ritenuto che tali diritti fossero stati violati e ha rimesso il caso alla Corte interamericana dei diritti dell’uomo. Con riferimento a questa nuova fase, nell’articolo si dà conto del “Escrito de Amici Curiae” presentato alla Corte dal Movimento per la vita italiano, dall’Istituto di Bioetica, dall’Asociación Crece Familia-CreceFam, dal Coordinamento di Human Life International e da Bioethics Defend Found. Nell’“Escrito” si afferma che il divieto del Costa Rica non viola la Convenzione americana sui diritti umani che afferma: “Ogni persona ha diritto al rispetto della propria vita. Tale diritto è protetto dalla legge e, in generale, è tutelato a partire dal momento del concepimento. Nessuno può essere privato arbitrariamente della vita (art. 4/1). Nel parere, inoltre, si avanzano argomenti di ordine scientifico e giuridico a sostegno del divieto di procreazione artificiale, in nome del riconoscimento della dignità umana e del conseguente diritto alla vita dell’essere umano nella fase più giovane della sua esistenza. Questo diritto, primo fra tutti, è già ampiamente accolto nella Convenzione americana sui diritti dell’uomo sottoscritta e ratificata dalla Repubblica del Costa Rica. ---------- The article deals with the “Case n. 12.361 Gretel Artavia Urilla et Al. vs. Costa Rica” which the Inter-American Court of Human Rights is going to decide. This case has its roots in the Supreme Court of Costa Rica’s decision (n. 2000-02306, March 15, 2000) which annulled the Decree n. 24029-S1 (February, 3, 1995) on human artificial procreation because of both formal and substantial aspects. Indeed, the Supreme Court of the Costa Rica considered that in vitro fertilization constituted a threat against human life before birth. Afterwards, the Inter-American Commission on Human Rights received a “Petición” which charged Costa Rica with a violation of the rights of some couples who wanted to achieve parenthood by medically assisted procreation. In short, according to Petitioner, the ban on in vitro fertilization violated the right to privacy and family life, the right to raise a family and equality before the law and equal protection established in the American Convention on human rights (“Pact of Saint José”). At the end of a long iter and an extended debate, the Inter-American Commission on Human Rights submitted the case to the jurisdiction of the Inter-American Court of Human Rights claiming the violation of said rights and asking the Court to rule and declare the international responsability of the Costa Rican Republic. Regarding this new stage, the article relates the “Escrito de Amici Curiae” sent to the Inter-American Commission on Human Rights by the Italian Movement for the Life, the Institute of Bioethics of teh Catholic University of the Sacred Heart, Asociación Crece Familia-CreceFam, Human Life International and the Bioethics Defense Fund. This “Escrito” argues that Costa Rica’s ban does not violate the American Convention on Human Rights which says that “Every person has the right to have his life respected. This right shall be protected by law and, in general, from the moment of conception. No one shall be arbitrarily deprived of his life” (article 4/1). Besides the “Escrito” presents scientific and legal arguments corroborating the ban on artificial human procreation in the light of modern idea of human rights, recognition of human dignity and the right to life of human beings in the youngest stages of their lives. This right, the primary or first right, is already widely recognized in the American Convention on Human Rights, signed and ratified by Costa Rica’s Republic.


Sympozjum ◽  
2021 ◽  
Vol 25 (2 (41)) ◽  
pp. 45-63
Author(s):  
Konrad Glombik

The problem of consent in the question of the right to life Under particular questions in the field of the right to life occurs the problem of consent which is discussed mainly in the context of legalization of abortion, euthanasia, in vitro fertilization and capital punishment. The question of consent in filed of the right to life is important for the discussions to this theme and is related to the understanding of nature of the right to life, both in juridical and moral perspective. The common accordance in the right to life has an impact on the actual solutions in the range of respect for life and concrete activities and choices of people in this field. The presented paper explains the nature of the consent in the question of the right to life, indicates problematic aspects in this regard and shows some arguments in the process of achievement of common accordance in the problem of the right to life. Wśród szczegółowych zagadnień w obszarze problematyki ochrony prawa do życia występuje zagadnienie konsensu, które jest dyskutowane głównie w kontekście legalizacji ustawodawstwa dotyczącego aborcji, eutanazji, sztucznego zapłodnienia, kary śmierci. Zagadnienie konsensu w kwestii prawa do życia jest kluczowym dla społecznych dyskusji na ten temat i wiąże się z rozumieniem natury prawa do życia, zarówno w perspektywie prawniczej, jak i moralnej. Problem ten ma także znaczenie dla przyjmowanych rozstrzygnięć w zakresie poszanowania życia ludzkiego oraz konkretnych działań i wyborów ludzi w tym obszarze. Niniejszy tekst jest próbą wyjaśnienia istoty konsensu w kwestii prawa do życia, wskazuje na kwestie problematyczne w dyskusjach na ten temat i przedstawia niektóre argumenty w procesie dochodzenia do powszechnej zgody w zakresie prawa do życia.


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