Consultation with the specialist

1994 ◽  
Vol 15 (5) ◽  
pp. 204-207
Author(s):  
Jeffrey S. Rubenstein
Keyword(s):  
Cerebral Cortex ◽  
Systemic Disease ◽  
Afferent Neurons ◽  
Altered Consciousness ◽  
Case Presentation ◽  
Good General Health ◽  
Ascending Reticular Activating System ◽  
Reticular Activating System ◽  
The Central Nervous System ◽  
The Brain

Case Presentation A 2-year-old boy is brought to the emergency room by ambulance after being found "unresponsive" by his parents. He has been in good general health, has had no fever or other symptoms of infectious processes, has been taking no medications, and was "his normal self" until immediately prior to being found. Patients who are unresponsive and unarousable are in coma. The term altered consciousness represents the spectrum of abnormalities that exists between the immediate capability for normal wakefulness and true coma. For the purposes of this review, the two terms will be used interchangeably because their causes are similar and usually differ only in severity. Pathophysiology Two areas of the brain are responsible for consciousness: the ascending reticular activating system (ARAS) and the cerebral cortex. The ARAS is located in the brain stem from the level of the medulla to the level of the midbrain and sends multiple afferent neurons to the cortex. Disruption of this system can lead to disorders of consciousness. The cerebral cortex is the much more common site where dysfunction can cause coma. Any injury or illness that affects the cerebral cortex globally can cause coma or altered consciousness. Differential Diagnosis Altered consciousness in children can be caused by injuries or illnesses that affect the central nervous system directly or can be a manifestation of other systemic disease (Table 1).

Glucuronyl 3-sulfate occurs exclusively on distal unmyelinated terminals of selected sensory neurons in the peripheral nervous system

1995 ◽  
Vol 53 ◽  
pp. 958-959
Author(s):  
S.S. Spicer ◽  
B.A. Schulte
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cerebral Cortex ◽  
Peripheral Nervous System ◽  
Sensory Neurons ◽  
Sensory Nerves ◽  
Tissue Antigens ◽  
The Central Nervous System ◽  
The Brain ◽  
Leu 7

Generation of monoclonal antibodies (MAbs) against tissue antigens has yielded several (VC1.1, HNK- 1, L2, 4F4 and anti-leu 7) which recognize the unique sugar epitope, glucuronyl 3-sulfate (Glc A3- SO4). In the central nervous system, these MAbs have demonstrated Glc A3-SO4 at the surface of neurons in the cerebral cortex, the cerebellum, the retina and other widespread regions of the brain.Here we describe the distribution of Glc A3-SO4 in the peripheral nervous system as determined by immunostaining with a MAb (VC 1.1) developed against antigen in the cat visual cortex. Outside the central nervous system, immunoreactivity was observed only in peripheral terminals of selected sensory nerves conducting transduction signals for touch, hearing, balance and taste. On the glassy membrane of the sinus hair in murine nasal skin, just deep to the ringwurt, VC 1.1 delineated an intensely stained, plaque-like area (Fig. 1). This previously unrecognized structure of the nasal vibrissae presumably serves as a tactile end organ and to our knowledge is not demonstrable by means other than its selective immunopositivity with VC1.1 and its appearance as a densely fibrillar area in H&E stained sections.

scholarly journals Efektivitas Otak Anak Usia Dini dalam Mengenal Calistung

2017 ◽  
Vol 1 (2) ◽  
pp. 207-222
Author(s):  
Zulfatun Anisah
Keyword(s):  
Central Nervous System ◽  
Cerebral Cortex ◽  
Cognitive Stimulation ◽  
Brain Cells ◽  
Abstract Thinking ◽  
Mental Age ◽  
The Central Nervous System ◽  
Iq Scores ◽  
The Brain ◽  
Child's Brain

The introduction of calistung in AUD focuses on brain optimization of children. The child's brain has a trillion brain cells and trillions of brain-nerve cell connections. Brain nerves. influenced by the number of myelin that awakened at the age of 0-2 years which will determine the ability of abstract thinking, scientific thinking at the formal stage of operations. The backbone and cerebral cortex are the central nervous system for humans. the physical body of the child can be trained through mild exercise. Other parts of the brain in the form of cerebral cortex handle the functions of intellectual and language. Parents or nannies can provide stimulation as needed. The results suggest that children from families with high language intake received higher IQ scores at age three. So is the case with children who get more cognitive stimulation, they are more skilled in language activities. Age of AUD precisely began to learn to read if it has reached the mental age, ie 5-5.5 years.

Consciousness Emanates from the Neuronal Network of Coordination, A Fact Endorsed by Preserved Consciousness in Focal Ischemic Infarctions

2021 ◽  
Vol 19 (3) ◽  
pp. 17-25
Author(s):  
Dr. Sohail Adnan ◽  
Dr. Mubasher Shah ◽  
Dr. Syed Fahim Shah ◽  
Dr. Fahad Naim ◽  
Dr. Akhtar Ali ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Neuronal Network ◽  
Brain Activity ◽  
Cross Sectional Study ◽  
Difficult Problem ◽  
Altered Consciousness ◽  
Cross Sectional ◽  
Consciousness Disorder ◽  
The Right ◽  
The Brain

Background: Consciousness has remained a difficult problem for the scientists to explore its relationship to the brain activity. This is the first paper that presents the significance of focal areas of the cerebral cortex for consciousness. Objectives: To determine if consciousness is produced by the activity of the whole brain or one of its focal areas. Methods: We have performed a prospective cross-sectional study in eighty patients of acute ischemic stroke. The neurovascular territory of the middle cerebral artery (MCA) was sectioned into four similar areas. The association of any of these focal areas to consciousness was observed after their dysfunction with ischemic strokes. Results: Of the eighty patients, 57.5 % were males and 42.5 % were females. Mean age was 63 years ± 7 SD. The righthanded patients were 90 % (72) of the whole sample. Focal areas of the right MCA were generally less prone to consciousness disorder. Average statistics of the focal infarctions of the right MCA showed no tendency for consciousness disorder on the Glasgow coma scale (GCS) [Mean GCS of all focal areas; 14.5, SD; 0.71, 95 % CI; 14.27 to 14.72, P= 0.0000004]. Altered consciousness with focal infarctions of the territory of left MCA was also less likely [Mean GCS of all focal areas; 14.2, SD; 1.01, 95 % CI; 13.88 to 14.51, P= 0.0004]. Conclusion: Consciousness is not determined by the activity of a focal area of the cerebral cortex. Perhaps, we get our consciousness from the activity of “Neuronal Network of Coordination”.

Developmental Overview of Central Neuroanatomy

2017 ◽  
Author(s):  
Peggy Mason
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Cerebral Cortex ◽  
Neural Tube ◽  
The Central Nervous System ◽  
Dorsal Telencephalon ◽  
Adult Spinal Cord ◽  
The Brain

The central nervous system develops from a proliferating tube of cells and retains a tubular organization in the adult spinal cord and brain, including the forebrain. Failure of the neural tube to close at the front is lethal, whereas failure to close the tube at the back end produces spina bifida, a serious neural tube defect. Swellings in the neural tube develop into the hindbrain, midbrain, diencephalon, and telencephalon. The diencephalon sends an outpouching out of the cranium to form the retina, providing an accessible window onto the brain. The dorsal telencephalon forms the cerebral cortex, which in humans is enormously expanded by growth in every direction. Running through the embryonic neural tube is an internal lumen that becomes the cerebrospinal fluid–containing ventricular system. The effects of damage to the spinal cord and forebrain are compared with respect to impact on self and potential for improvement.

scholarly journals Laser-Induced Evoked Potentials in the Brain after Nonperceptible Optical Stimulation at the Neiguan Acupoint: A Preliminary Report

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Gerhard Litscher ◽  
Guenther Bauernfeind ◽  
Gernot Mueller-Putz ◽  
Christa Neuper
Keyword(s):  
Evoked Potentials ◽  
University Of Technology ◽  
Ascending Reticular Activating System ◽  
Cerebral Evoked Potentials ◽  
Reticular Activating System ◽  
Joint Study ◽  
Laser Needle ◽  
Medical University ◽  
The Brain ◽  
Needle Stimulation

We report on small but reproducible human cerebral evoked potentials after bilateral nonperceptible laser needle (658 nm, 40 mW, 500 μm, 1 Hz) irradiation of the Neiguan acupoint (PC6). The results which are unique in scientific literature were obtained in a 26-year-old female healthy volunteer within a joint study between the Medical University of Graz, the Karl-Franzens University of Graz, and the Graz University of Technology. The findings of the 32-channel evoked potential analysis indicate that exposure to laser needle stimulation with a frequency of 1 Hz can modulate the ascending reticular activating system. Further studies are absolutely necessary to confirm or refute the preliminary findings.

scholarly journals Rosai-Dorfman Disease – A Case Report

2019 ◽  
Author(s):  
Oldřich Medek ◽  
Petra Kašparová ◽  
Michael Bartoš ◽  
Petr Krůpa ◽  
Blanka Klimova ◽  
...  
Keyword(s):  
Resonance Imaging ◽  
Case Presentation ◽  
Adjacent Tissue ◽  
Organ Systems ◽  
Rosai Dorfman Disease ◽  
History Of Disease ◽  
History Of ◽  
The Central Nervous System ◽  
Significant Regression ◽  
The Brain

Abstract Background: The aim is to discuss a case of a meningeal form of Rosai-Dorfman disease, is a rare haematological disease, primarily affecting lymph nodes, but it can also affect most organ systems of the human body, including the central nervous system. So far, there have been over 650 cases of this disease described in literature. Case presentation: This report deals with a young, 40-year-old man with a negative history of disease, who observed a loss of smell and taste, without a history of anxiety or an injury. The patient was hospitalized and completely examined. Consequently, a navigational biopsy of the brain was indicated. The findings showed that the patient suffered from Rosai-Dorfman disease with reactive gliosis in adjacent tissue without evidence of amyloid. Conclusions: In January, March, and then in May 2018, the patient was checked for the magnetic resonance imaging of the brain, according to which there was a significant regression of the finding, and according to the outpatient reports of the same year, the taste and vision of the left eye are gradually being adjusted. The patient was treated with new corticosteroids, which proved to be effective.

Awaking the Cortex

2019 ◽  
pp. 103-122
Author(s):  
Alan J. McComas
Keyword(s):  
Cerebral Cortex ◽  
Brain Stem ◽  
Reticular Formation ◽  
Cortical Excitability ◽  
Reticular Activating System ◽  
The Brain

This chapter tells the story of the discovery of the reticular activating system. At the same time, the chapter traces various attempts to address the larger question of “waking” the cortex and bringing it to a state of consciousness. It turns to two scientists, Horace Magoun and Giuseppe Moruzzi, both of whom conducted experiments to explore the possible effects on the cerebral cortex of stimulating the brain stem. Since the brain’s reticular formation ended just below the thalamus on either side, it was logical to see if it might alter cortical excitability. The chapter shows how Magoun and Moruzzi came to the conclusion that, through its action on the excitability of the cortex, the reticular formation could control the wakefulness of the brain.

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