scholarly journals Veleszületett csírahiánnyal társuló skeletalis eltérések vizsgálata

2019 ◽  
Vol 160 (6) ◽  
pp. 214-219
Author(s):  
I. Krisztina Mártha ◽  
Alina Cămărășan ◽  
Silvia Izabella Pop ◽  
Bernadette Kerekes Máthé
Keyword(s):  
Orthodontic Treatment ◽  
Matched Control ◽  
Daily Practice ◽  
Growth Direction ◽  
Control Group ◽  
X Ray ◽  
Skeletal Class ◽  
Measurement Results ◽  
The University ◽  
Age And Sex

Abstract: Introduction: The incidence of congenital hypodontia is increasing in daily practice. Early diagnosis of this dental disorder and the associated skeletal malocclusions is crucial for successful and stable final rehabilitation. Aim: Comparison of cephalometric findings of patients with hypodontia of 1–4 teeth with the measurement results of the control group without teeth agenesis. Material and method: We evaluated the lateral X-ray of 41 patients with 1–4 teeth agenesis selected from patients referred for orthodontic treatment to the Orthodontic Department of the University of Medicine and Pharmacy from Târgu Mureş within a two-year period. The results were compared with the values of the age and sex matched control group. Results: Bilateral upper incisor and lower bicuspid were missing in most of the hypodontia cases. When looking at the NSGn angle predicting the growth direction of the mandible, statistically significant differences were found between the male (p = 0.012), the front (p = 0.010) and the hypodontia group (p = 0.024) and the control group. Regarding the ANB angle, which shows the sagittal position of the maxilla to the mandible, statistically significant differences were found between the subgroups (women, men, anterior or posterior hypodontia) and the control group. Conclusion: Larger number of skeletal class 3 and vertical hypodivergent tendency were observed in the hypodontia group. Orv Hetil. 2019; 160(6): 214–219.

scholarly journals Circulating miRNA-202-3p is a potential novel biomarker for diagnosis of type 1 gastric neuroendocrine neoplasms

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dou Dou ◽  
Xiao-kou Li ◽  
Qi-sheng Xia ◽  
Ying-ying Chen ◽  
Yuan-liang Li ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Matched Control ◽  
Future Research ◽  
Control Group ◽  
Neuroendocrine Neoplasms ◽  
Diagnostic Biomarkers ◽  
Standard Curve ◽  
Qrt Pcr ◽  
Age And Sex

Abstract Background Currently, there are no circulating diagnostic biomarkers for gastric neuroendocrine neoplasms (g-NENs). In previous studies, we found that miRNA-202-3p is overexpressed in the tumour tissue of type 1 g-NEN. We speculated that miRNA-202-3p is also likely to be highly expressed in circulating blood. Methods A total of 27 patients with type 1 g-NEN and 27 age- and sex-matched control participants were enrolled in this study. The miRNA-202-3p levels in serum obtained from the participants were measured by qRT‐PCR. The expression level of miRNA-202-3p in the samples was calculated by comparison with a standard curve. Results The clinical characteristics of the patients were similar to those of the patient samples in previous reports. Expression of miRNA-202-3p was significantly higher in the patient group (3.84 × 107 copies/nl) than in the control group (0.635 × 107 copies/nl). The area under the ROC curve (AUC) was 0.878 (95% CI: 0.788–0.968), and the optimal cut-off point was approximately 1.12 × 107 copies/nl. The sensitivity and specificity were 88.9% and 77.8%, respectively. Conclusion This study suggests that miRNA-202-3p is potentially useful as a biomarker of type 1 g-NEN; further investigation and verification should be performed in future research.

Enlargement of cerebrospinal fluid spaces in long-term benzodiazepine abusers

1987 ◽  
Vol 17 (4) ◽  
pp. 869-873 ◽  
Author(s):  
C. Schmauss ◽  
J.-C. Krieg
Keyword(s):  
Low Dose ◽  
Matched Control ◽  
Control Group ◽  
High Dose ◽  
Withdrawal Therapy ◽  
The Mean ◽  
Dose Dependent ◽  
Dose Dependent Effect ◽  
Age And Sex

SynopsisIn 17 benzodiazepine (BDZ) dependent in-patients a CT scan was performed before initiation of withdrawal therapy. The evaluation of the ventricular to brain ratio (VBR) by standardized and computerized measurements revealed significantly higher mean VBRs for both high-and low-dose BDZ-dependent patients compared to the mean VBR of an age- and sex-matched control group. In addition, the mean VBR of high-dose BDZ-dependent patients (N = 8) was significantly higher than the mean VBR of low-dose BDZ-dependent patients (N = 9). This difference could not be accounted for by the age of the patients or duration of BDZ-dependency and, therefore, suggests a dose-dependent effect of BDZs on the enlargement of internal CSF-spaces. On the other hand, higher values for the width of external CSF-spaces were found to be related to increasing age of the patients and duration of BDZ-dependency.

scholarly journals Root Dimensions in Patients with Mild Hypodontia and a Control Group

2019 ◽  
Vol 13 (04) ◽  
pp. 574-580
Author(s):  
Khaled Khalaf ◽  
Zahra Seraj ◽  
Hesham Hussein ◽  
Mahmoud Mando
Keyword(s):  
Matched Control ◽  
Permanent Teeth ◽  
Cervical Region ◽  
Control Group ◽  
Third Molars ◽  
Control Groups ◽  
Implant Placement ◽  
Dental Hospital ◽  
The University ◽  
And Control

Abstract Objectives The aim of this study was to compare root dimensions (length and mesiodistal widths) between subjects with mild hypodontia and an age- and sex-matched control group. Materials and Methods Root dimension measurements of all permanent teeth excluding third molars were made on standardly taken orthopantomograms of 50 individuals (25 hypodontia and 25 controls) attending the University of Sharjah Dental Hospital. The length and two mesiodistal widths were measured for each fully formed root. The length of the root was measured digitally by drawing a line from the midpoint and bisecting the mesiodistal cemento-enamel junction (CEJ) of the tooth and extended to its apex. The mesiodistal widths of each root were measured at the cervical region and at half way of and perpendicular to the length of the root. Statistical Analysis Two sample t-tests were used to compare root dimension measurements between the hypodontia and control groups. Results There were no significant differences between genders with regard to root length or widths measurements, and therefore genders were combined for further analysis. Patients with hypodontia have significantly shorter root lengths than controls for the upper central incisors, upper canines, first premolars, and lower first molars (p < 0.05). Similarly, root width at the midpoint of the root was found to be less in hypodontia group than that in controls for the upper central incisors, lower first premolars, upper first molars, and all second premolars (p < 0.05). Similar pattern of differences was found with regard to the root width at the cervical region (p < 0.05). Conclusions Patients with hypodontia have shorter and narrower roots of the whole permanent dentition except the upper lateral incisors, lower incisors, lower canines, and all second molars when compared with controls. In effect, this may affect the orthodontic treatment planning and implant placement.

scholarly journals Orthodontics is temporomandibular disorder–neutral

2015 ◽  
Vol 86 (4) ◽  
pp. 649-654 ◽  
Author(s):  
Daniele Manfredini ◽  
Edoardo Stellini ◽  
Antonio Gracco ◽  
Luca Lombardo ◽  
Luca Guarda Nardini ◽  
...  
Keyword(s):  
Temporomandibular Disorders ◽  
Joint Pain ◽  
Orthodontic Treatment ◽  
Normal Values ◽  
Temporomandibular Disorder ◽  
Control Group ◽  
Disc Displacement ◽  
History Of ◽  
Clinically Significant ◽  
Age And Sex

ABSTRACT Objectives:  To assess if subjects with a clinical diagnosis of temporomandibular disorders (TMDs) have a similar prevalence of orthodontic history as a population of TMD-free individuals and to assess if those subjects who have a history of ideal orthodontics have fewer symptoms than those with a history of nonideal orthodontics. Materials and Methods:  Two groups of age- and sex-matched individuals belonging to either a study (“TMD”) or a control group were recruited. Subjects who underwent orthodontic treatment were classified as having a history of ideal or nonideal orthodontics based on the current presence of normal values in five reference occlusal features. Results:  The correlation with a history of orthodontic treatment was not clinically significant for any of the TMD diagnoses (ie, muscle pain, joint pain, disc displacement, arthrosis), with Phi (Φ) coefficient values within the −0.120 to 0.058 range. Within the subset of patients with a history of orthodontics, the correlation of ideal or nonideal orthodontic treatment with TMD diagnoses was, in general, not clinically relevant or was weakly relevant. Conclusions:  Findings confirmed the substantial absence of clinically significant effects of orthodontics as far as TMD is concerned. The very low correlation values of a negative or positive history of ideal or nonideal orthodontics with the different TMD diagnoses suggest that orthodontic treatment could not have a true role for TMD.

scholarly journals Craniofacial And Dentoalveolar Morphology In Individuals With Prader-Willi Syndrome: A Case-Control Study.

2021 ◽  
Author(s):  
Gisela Vasconcelos ◽  
Jo Stenehjem ◽  
Stefan Axelsson ◽  
Ronnaug Saeves
Keyword(s):  
Young Adults ◽  
Class Ii ◽  
Growth Direction ◽  
Control Group ◽  
Craniofacial Growth ◽  
Prader Willi Syndrome ◽  
Class Iii ◽  
Skeletal Class ◽  
Skeletal Class Ii ◽  
Lateral Cephalograms

Abstract Background: Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder with distinct genetic and clinical features. Among other clinical symptoms, PWS is characterized by severe infantile hypotonia with feeding problems, childhood onset hyperphagia, obesity, scoliosis, short stature combined with growth hormone deficiency and developmental delay. PWS is associated with facial dysmorphology, orofacial dysfunction, oral abnormalities, low salivary flow and subsequent severe tooth wear. Little is known about the craniofacial growth direction or dental and skeletal relationships in individuals with PWS in different ages. The purpose of this study was to assess the craniofacial and dentoalveolar characteristics and to investigate the craniofacial growth direction separately in children, young adults and adults with PWS, using a cephalometric analysis of lateral cephalograms. Results: Lateral cephalograms of 42 individuals with a confirmed genetic diagnosis of PWS were analysed and divided into three groups according to their age: Children (< 12 years), young adults (12 – 20 years) and adults (> 20 years). Cephalometric variables were compared between PWS patients and healthy age- and sex-matched controls.Significant deviations and distinct craniofacial patterns were found in children, young adults and adults with PWS compared with the control group. Children showed retrognatic mandible with a skeletal class II relationship, posterior growth direction and longer anterior face height. The young adults had smaller cranial base angle, a skeletal class II pattern and a higher anterior lower face than the control group. Adults with PWS had a prognathic mandible, skeletal class III relationship with anterior growth direction, more retroclined lower incisors and proclined upper incisors than the controls. Similar results were found when comparing the three groups with PWS; the adults had a prognathic mandible, skeletal class III pattern and anterior growth direction. Children had a retropositioned mandibula, skeletal class II relationship and posterior growth direction. Conclusion: This study may contribute to a better understanding of the craniofacial growth pattern in children, young adults and adults with PWS and may have a clinical importance when planning dental treatment, such as prosthodontics and/or orthodontics.

Migraine Patients Experience Poorer Subjective Well-Being/Quality of Life Even Between Attacks

Cephalalgia ◽  
1995 ◽  
Vol 15 (1) ◽  
pp. 31-36 ◽  
Author(s):  
CGH Dahlöf ◽  
E Dimenäs
Keyword(s):  
Migraine Patient ◽  
Matched Control ◽  
Well Being ◽  
Control Group ◽  
Subjective Well Being ◽  
Subjective Symptoms ◽  
Matched Control Group ◽  
Patients Experience ◽  
Age And Sex

The aim of the present study was to compare the general well-being of migraine patients between attacks with that of an age- and sex-matched control group. One hundred and forty-five consecutive and eligible patients at the Gothenburg Migraine Clinic were asked about their well-being and their complaints. Using three self-administered standardized questionnaires, the Minor Symptoms Evaluation Profile (MSEP), Subjective Symptoms Assessment Profile (SSAP) and the Psychological General Well-Being (PGWB) Index, evaluable responses were obtained from 138 migraine patients. Compared with control subjects, migraineurs perceived more symptoms and greater emotional distress as well as disturbed contentment, vitality and sleep. It is concluded that the general well-being of the migraine patient is impaired, even between the attacks.

scholarly journals Corneal Epithelial Damage and Impaired Tear Functions in Patients with Inflamed Pinguecula

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Erkut Küçük ◽  
Uğur Yılmaz ◽  
Kürsad Ramazan Zor
Keyword(s):  
Matched Control ◽  
Tear Film ◽  
Control Group ◽  
Healthy Controls ◽  
Epithelial Defect ◽  
Epithelial Integrity ◽  
Corneal Epithelial ◽  
Matched Control Group ◽  
Age And Sex ◽  
Fellow Eyes

Purpose. In this study, we evaluated corneal epithelial integrity and tear film parameters in patients with inflamed pinguecula and compared these findings with their fellow eyes and with healthy controls. Methods. We evaluated the fluorescein staining properties and performed the tear break-up time (TBUT) test and Schirmer 2 test (ST2) measurements of 32 patients who had symptomatic unilateral inflamed pinguecula and compared the results with their fellow eyes and also with an age- and sex-matched control group. Results. Twenty-three eyes (72%) in the inflamed pinguecula group and 1 eye (3.1%) in the fellow eyes group had punctate epithelial staining (PES) or epithelial defect on the nasal cornea (p<0.001). There was no PES or epithelial defect in the control group. Eyes with inflamed pinguecula (n = 32) had lower TBUT and ST2 values compared to the control group (n = 32) (p<0.001 for both). Fellow eyes (n = 32) also had lower TBUT and ST2 values compared to the control group (p=0.003 for both). There was no difference in the TBUT and ST2 results between the eyes with inflamed pinguecula and fellow eyes (p=0.286 and p=0.951, respectively). Conclusion. A high percentage of eyes with inflamed pinguecula had nasal corneal epithelial staining or epithelial defect. We also found lower TBUT and ST2 results in eyes with inflamed pinguecula and the fellow eyes compared to the control group. These findings may be important in pathogenesis of pinguecula and pterygium and also in uncovering their relation.

Fatigue and health-related quality of life in elderly patients with and without heart failure in primary healthcare

2007 ◽  
Vol 6 (3) ◽  
pp. 208-215 ◽  
Author(s):  
Lena Hägglund ◽  
Kurt Boman ◽  
Mona Olofsson ◽  
Christine Brulin
Keyword(s):  
Heart Failure ◽  
Primary Healthcare ◽  
Matched Control ◽  
Control Group ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Patient Groups ◽  
Age And Sex

Background Patients with heart failure (HF) in primary healthcare are in many respects not comparable to those in specialized care and the knowledge about different patient groups with and without HF is limited. Aims To compare fatigue and health-related quality of life (Hr-QoL) when adjusting for age, gender and social provision in patients with confirmed HF ( n=49) to a group of patients with symptoms indicating HF but without HF (NHF, n=59) and to an age-and sex-matched control-group ( n=40). Method A questionnaire including the Multidimensional Fatigue Inventory, the SF-36, and the Social Provisions Scale was used. Results The average age in all groups was 78 years. Patients in the HF and NHF groups reported worse physical QoL and more general and physical fatigue than the control group. HF patients had worse general health than the NHF group. Conclusion Elderly patients in primary healthcare with confirmed heart failure and patients with symptoms similar to heart failure perceived they had a significantly worse physical QoL and more general and physical fatigue than an age- and sex-matched control group. The similarities between the patient groups indicate the importance of the symptom experience for Hr-QoL.

Reinke's oedema and thyroid function

1991 ◽  
Vol 105 (4) ◽  
pp. 291-292 ◽  
Author(s):  
A. White ◽  
D. W. Sim ◽  
A. G. D. Maran
Keyword(s):  
Thyroid Function ◽  
Matched Control ◽  
Normal Population ◽  
Vocal Folds ◽  
Thyroid Stimulating Hormone ◽  
Aetiological Factor ◽  
Controlled Study ◽  
Control Group ◽  
Matched Control Group ◽  
Age And Sex

AbstractReinke's oedema (RO) of the vocal folds is a condition of unknown aetiology. Cigarette smoking and vocal abuse may contribute to its development. Hypo thy roidism has been described as an aetiological factor but, to date, no controlled study has been published confirming this association. This prospective, controlled study compared thyroid function in 61 consecutive RO patients with an age and sex matched control group (n = 65) without laryngeal disease. Thyroid function was assessed by measuring serum thyroid stimulating hormone (TSH), free thyroxine (T4) and tri-iodothyronine (T3). Hypothyroidism was diagnosed when TSH was above normal with a T3 and T4 below the normal range.Four RO patients were hypothyroid at the time of diagnosis, compared to five of the control group. Six RO patients had past or present hypothyroidism compared to seven of the controls. One RO patient and two controls were euthyroid with marginally elevated TSH levels. Although the incidence of hypothyroidism in this group of Reinke's oedema patients is higher than expected in a normal population, it is similar to that in an age and sex matched control group, reflecting the prevalence of hypothyroidism in middle aged women.This study suggests that hypothyroidism is not an aetiological factor in the development of Reinke's oedema.

DOZ047.54: Fundoplication outcomes in children with esophageal atresia

2019 ◽  
Vol 32 (Supplement_1) ◽  
Author(s):  
E Chung ◽  
M van Lennep ◽  
R Saoji ◽  
A Jiwane ◽  
M W N Oomen ◽  
...  
Keyword(s):  
Esophageal Atresia ◽  
Matched Control ◽  
Cumulative Risk ◽  
Control Group ◽  
Postoperative Dysphagia ◽  
Long Gap ◽  
Type C ◽  
New Diagnosis ◽  
Age And Sex

Abstract Background In esophageal atresia (EA) patients, cumulative risk of having a fundoplication ranges from 0% to 45%, with long gap patients with recurrent strictures at even higher risk. However, there are no controlled trials evaluating the outcomes postfundoplication. We hypothesized that children with EA undergoing fundoplication will suffer from more postoperative dysphagia compared to non-EA patients as the fundoplication increases the resistance to esophageal bolus flow, which is already hampered by abnormal motility. Aims Our study aimed to compare outcomes in EA patients with age- and sex-matched control patients postfundoplication. Methods This was an international multicenter retrospective cohort study. All EA patients who had fundoplication between 2006 and 2017 during this period were included. Data were also collected from age- and sex-matched children without EA who underwent fundoplication. Results A total of 40 EA patients had fundoplication during this period. Of the EA patients 82.5% were type C, and 82.5% were long gap. Table 1 compares EA patients with controls. Significantly more EA patients were failing to thrive, on nasogastric/gastrostomy feeds at time of surgery and needed gastrostomy placement at time of fundoplication compared to controls. A total of 17.5% of EA patients developed infection and 22.5% a leak postfundoplication. EA patients had postoperative dysphagia and oral aversion significantly more often than controls. Of 90% of EA patients had recurrence of gastrointestinal or respiratory symptoms, 35% had recurrent strictures, 5% had a new diagnosis of eosinophilic esophagitis postfundoplication. Median time to symptom recurrence was 64 days (12–165 days), 90% were back on PPI and 7.5% had redofundoplication. Conclusions Our study is the first to examine postfundoplication outcomes in EA patients and compare these with a matched control group. EA patients had significantly more dysphagia and oral aversion postfundoplication and majority were back on PPI within two months of surgery. Based on these data, the role of fundoplication in EA patients should be reconsidered. Prospective data are urgently needed.

Sign in / Sign up

Export Citation Format

Share Document