The Necessity for Scale Up in R&D: Approach for Waste Immobilisation in Cement by BNFL

1995 ◽  
Vol 412 ◽  
Author(s):  
Graham A Fairhall ◽  
Eric W Miller
Keyword(s):  
Material Properties ◽  
Large Scale ◽  
Scale Up ◽  
Scaling Up ◽  
Full Scale ◽  
Physical Parameters ◽  
Wide Range ◽  
Regulatory Bodies ◽  
Major Factors

AbstractThe full scale processing of nuclear wastes immobilised in cement utilises a wide range of chemical and physical parameters. The success of this work however, involves many factors and material properties which are affected by the actual scaling up processes. The paper outlines the approach and experience gained by BNFL to recognise and evaluate the major factors involved in order to successfully produce large scale stable products acceptable to the appropriate regulatory bodies and suitable for long term disposal.

scholarly journals Global soil moisture data derived through machine learning trained with in-situ measurements

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Sungmin O. ◽  
Rene Orth
Keyword(s):  
Machine Learning ◽  
Soil Moisture ◽  
Large Scale ◽  
Short Term Memory ◽  
Temporal Dynamics ◽  
Soil Moisture Data ◽  
Wide Range ◽  
Global Soil

AbstractWhile soil moisture information is essential for a wide range of hydrologic and climate applications, spatially-continuous soil moisture data is only available from satellite observations or model simulations. Here we present a global, long-term dataset of soil moisture derived through machine learning trained with in-situ measurements, SoMo.ml. We train a Long Short-Term Memory (LSTM) model to extrapolate daily soil moisture dynamics in space and in time, based on in-situ data collected from more than 1,000 stations across the globe. SoMo.ml provides multi-layer soil moisture data (0–10 cm, 10–30 cm, and 30–50 cm) at 0.25° spatial and daily temporal resolution over the period 2000–2019. The performance of the resulting dataset is evaluated through cross validation and inter-comparison with existing soil moisture datasets. SoMo.ml performs especially well in terms of temporal dynamics, making it particularly useful for applications requiring time-varying soil moisture, such as anomaly detection and memory analyses. SoMo.ml complements the existing suite of modelled and satellite-based datasets given its distinct derivation, to support large-scale hydrological, meteorological, and ecological analyses.

Coupled Thermo-Hydro-Geochemical Models of Engineered Barrier Systems: The Febex Project

2000 ◽  
Vol 663 ◽  
Author(s):  
J. Samper ◽  
R. Juncosa ◽  
V. Navarro ◽  
J. Delgado ◽  
L. Montenegro ◽  
...  
Keyword(s):  
Large Scale ◽  
Reference Model ◽  
Numerical Models ◽  
Full Scale ◽  
Small Scale ◽  
Model Parameters ◽  
In Situ Test ◽  
Wide Range ◽  
Engineered Barrier

ABSTRACTFEBEX (Full-scale Engineered Barrier EXperiment) is a demonstration and research project dealing with the bentonite engineered barrier designed for sealing and containment of waste in a high level radioactive waste repository (HLWR). It includes two main experiments: an situ full-scale test performed at Grimsel (GTS) and a mock-up test operating since February 1997 at CIEMAT facilities in Madrid (Spain) [1,2,3]. One of the objectives of FEBEX is the development and testing of conceptual and numerical models for the thermal, hydrodynamic, and geochemical (THG) processes expected to take place in engineered clay barriers. A significant improvement in coupled THG modeling of the clay barrier has been achieved both in terms of a better understanding of THG processes and more sophisticated THG computer codes. The ability of these models to reproduce the observed THG patterns in a wide range of THG conditions enhances the confidence in their prediction capabilities. Numerical THG models of heating and hydration experiments performed on small-scale lab cells provide excellent results for temperatures, water inflow and final water content in the cells [3]. Calculated concentrations at the end of the experiments reproduce most of the patterns of measured data. In general, the fit of concentrations of dissolved species is better than that of exchanged cations. These models were later used to simulate the evolution of the large-scale experiments (in situ and mock-up). Some thermo-hydrodynamic hypotheses and bentonite parameters were slightly revised during TH calibration of the mock-up test. The results of the reference model reproduce simultaneously the observed water inflows and bentonite temperatures and relative humidities. Although the model is highly sensitive to one-at-a-time variations in model parameters, the possibility of parameter combinations leading to similar fits cannot be precluded. The TH model of the “in situ” test is based on the same bentonite TH parameters and assumptions as for the “mock-up” test. Granite parameters were slightly modified during the calibration process in order to reproduce the observed thermal and hydrodynamic evolution. The reference model captures properly relative humidities and temperatures in the bentonite [3]. It also reproduces the observed spatial distribution of water pressures and temperatures in the granite. Once calibrated the TH aspects of the model, predictions of the THG evolution of both tests were performed. Data from the dismantling of the in situ test, which is planned for the summer of 2001, will provide a unique opportunity to test and validate current THG models of the EBS.

scholarly journals Changes to the chemical state of the northern hemisphere atmosphere during the second half of the twentieth century

2016 ◽  
Author(s):  
Mike J. Newland ◽  
Patricia Martinerie ◽  
Emmanuel Witrant ◽  
Detlev Helmig ◽  
David R. Worton ◽  
...  
Keyword(s):  
Northern Hemisphere ◽  
Large Scale ◽  
Atmospheric Composition ◽  
The Arctic ◽  
Major Influence ◽  
Secondary Products ◽  
Alkyl Nitrates ◽  
Mixing Ratios ◽  
Wide Range

Abstract. The NOX (NO and NO2) and HOX (OH and HO2) budgets of the atmosphere exert a major influence on atmospheric composition, controlling removal of primary pollutants and formation of a wide range of secondary products, including ozone, that can influence human health and climate. However, there remain large uncertainties in the changes to these budgets over recent decades. Due to their short atmospheric lifetimes, NOX and HOX are highly variable in space and time, and so the measurements of these species are of very limited value for examining long term, large scale changes to their budgets. Here, we take an alternative approach by examining long-term atmospheric trends of alkyl nitrates, the formation of which is dependent on the atmospheric NO / HO2 ratio. We derive long term trends in the alkyl nitrates from measurements in firn air from the NEEM site, Greenland. Their mixing ratios increased by a factor of 4–5 between the 1970s and 1990s. This was followed by a steep decline to the sampling date of 2008. Moreover, we examine how the trends in the alkyl nitrates compare to similarly derived trends in their parent alkanes (i.e. the alkanes which, when oxidised in the presence of NOX, lead to the formation of the alkyl nitrates). The ratios of the alkyl nitrates to their parent alkanes increase from around 1970 to the late 1990's consistent with large changes to the [NO] / [HO2] ratio in the northern hemisphere atmosphere during this period. These could represent historic changes to NOX sources and sinks. Alternatively, they could represent changes to concentrations of the hydroxyl radical, OH, or to the transport time of the air masses from source regions to the Arctic.

scholarly journals Citizen workshops in public libraries to disseminate and discuss primary care research results: a scaling-up study

2020 ◽  
Author(s):  
José Massougbodji ◽  
Hervé Tchala Vignon Zomahoun ◽  
Evehouenou Lionel Adisso ◽  
Jasmine Sawadogo ◽  
Valérie Borde ◽  
...  
Keyword(s):  
Knowledge Translation ◽  
Financial Incentives ◽  
General Public ◽  
Large Scale ◽  
Public Libraries ◽  
Scale Up ◽  
Scaling Up ◽  
Computer Assisted ◽  
Knowledge Gain ◽  
Research Results

Abstract Background Little is known about engaging patients and stakeholders in the process of scaling up effective knowledge translation interventions targeting the general public. Using an integrated knowledge translation approach, we aimed to scale up and evaluate an effective pilot program of disseminating research results in public libraries. Methods We conducted a scaling-up study targeting the general public. Based on our successful pilot project, we co-developed and implemented a larger-scale program of free citizen workshops in public libraries, this time in close research partnership with stakeholders and patient representatives. Citizen workshops, each facilitated by one participating physician and one science communicator, consisted of a 45-min computer-assisted presentation and a 45-min open exchange. Additional scale-up costs included offering financial incentives to stakeholders involved and the purchase of audio-visual equipment. The intervention outcome was knowledge gained. Scale-up outcomes were satisfaction, appropriateness, coverage, time and costs. An evaluation questionnaire was used to collect data of interest. Both quantitative and qualitative analyses were performed. Results The workshop theme chosen by patient and stakeholder representatives was the high prevalence of medication overuse among people over 65 years of age. From April to May 2019, 26 workshops were given in 25 public libraries reaching 362 people. Eighteen participating physicians and six science communicators facilitated the workshops. Participants reported significant knowledge gain (mean difference 2.1, 95% CI 2.0–2.2, P < .001). Median score for overall public satisfaction was 9/10 (IQR 8–10). A high level of appropriateness of the workshops was globally rated by the public participants Coverage was 92.6% of the total number of public libraries targeted. Costs were $6,051.84 CAD for workshop design and $22,935.41 CAD for scaling them up. Conclusion This project successfully established a large-scale and successful KT bridge between researchers, clinicians, and citizens via public libraries. This study provides a model for a dissemination practice that benefits the general public by both engaging them in the dissemination process and by targeting them directly.

scholarly journals O7C.2 Developing a measuring strategy for monitoring and evaluation of a national occupational health intervention programme in great britain (GB)

2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A64.3-A65
Author(s):  
Yiqun Chen ◽  
Andrew Curran
Keyword(s):  
Occupational Health ◽  
Large Scale ◽  
National Level ◽  
Health And Safety ◽  
Monitoring And Evaluation ◽  
Work Related ◽  
Measurement Framework ◽  
Wide Range ◽  
Over Time

The Health and Safety Executive (HSE) is the GB regulator for health and safety at work. The HSE Health and Work (H&W) program designs and carries out a wide range of interventions; including inspection, enforcement and other regulatory activities as well as prevention; targeting priority health conditions in high-risk sectors. It is anticipated that long-term, sustainable and coordinated actions developed as part of the program will over time improve awareness, behaviors, control of exposures, and, as a result, prevent work-related ill health in GB workforce.An HSE Measuring Strategy, together with measurement framework and principles, has been developed. The measurement framework draws together data systems, covering Attitudes (A), Behaviors (B), Control of exposures (C), and Disease and work-related ill health reduction (D), based on a simple model to provide evidence required for evaluating the short, medium and long term impacts of the large scale and complex H&W program on the GB health and safety system. The Strategy gives a new focus on measuring behavioral changes and risk reductions; and emphasizes longitudinal measurement designs to assess progress over time.For developing the Strategy, workshops were organized to bring stakeholders across HSE to review existing systems for conducting population surveys, collecting exposure intelligence and occupational health surveillance, which have contributed to forming a long-term vision of fit-for-purpose measurement systems.We will present the development of the Strategy and the plans to implement it with the H&W program, which requires close collaborations between epidemiologists and social researchers, policy makers, and other multidisciplinary regulatory specialists. The lessons learnt will help HSE towards building the right evidence base for monitoring and evaluation of a range of national level intervention programs for work-related ill health prevention.©British Crown copyright (2019)

scholarly journals Artist: fast radiative transfer for large-scale simulations of the epoch of reionization

2019 ◽  
Vol 489 (4) ◽  
pp. 5594-5611 ◽  
Author(s):  
Margherita Molaro ◽  
Romeel Davé ◽  
Sultan Hassan ◽  
Mario G Santos ◽  
Kristian Finlator
Keyword(s):  
Radiative Transfer ◽  
Large Scale ◽  
Power Spectra ◽  
Physical Parameters ◽  
Speed Of Light ◽  
Photon Propagation ◽  
Wide Range ◽  
Gas Ionization ◽  
Excursion Set ◽  
Large Scale Simulations

ABSTRACT We introduce the ‘Asymmetric Radiative Transfer In Shells Technique’ (artist), a new method for photon propagation on large scales that explicitly conserves photons, propagates photons at the speed of light, approximately accounts for photon directionality, and closely reproduces results of more detailed radiative transfer (RT) methods. Crucially, it is computationally fast enough to evolve the large cosmological volumes required to predict the 21cm power spectrum on scales that will be probed by future experiments targeting the epoch of reionization (EoR). Most seminumerical models aimed at predicting the EoR 21cm signal on these scales use an excursion set formalism (ESF) to model the gas ionization, which achieves computational viability by making a number of approximations. While artist is still roughly two orders of magnitude slower than ESF, it does allow to model the EoR without the need for such approximations. This is particularly important when considering a wide range of reionization scenarios for which artist would help limit the assumptions made. By implementing our RT method within the seminumerical code simfast21, we show that Artist predicts a significantly different evolution for the EoR ionization field compared to the code’s native ESF. In particular, artist predicts up to a factor of two difference in the power spectra, depending on the physical parameters assumed. Its application to large-scale EoR simulations will therefore allow more physically motivated constraints to be obtained for key EoR parameters. In particular, it will remove the need for the artificial rescaling of the escape fraction.

Salvage harvesting – past lessons and future issues

2006 ◽  
Vol 82 (1) ◽  
pp. 48-53 ◽  
Author(s):  
David Lindenmayer
Keyword(s):  
Environmental Impacts ◽  
Large Scale ◽  
Natural Disturbance ◽  
Forest Planning ◽  
Salvage Logging ◽  
Eastern Australia ◽  
Wide Range ◽  
Natural Resource Managers ◽  
Salvage Harvesting

The increasing prevalence and/or increasing intensity of large-scale natural disturbance events in forests means that post-disturbance salvage logging is becoming more widespread. Salvage logging can have a wide range of environmental impacts, but some of these are not well known or not well understood by policy makers and natural resource managers. Some of these impacts are briefly summarized in this paper. Improved long-term forest planning needs to be embraced that takes into account the not only the environmental but also the social and environmental impacts of salvage harvesting. Past mistakes and future opportunities associated with salvage harvesting are illustrated by a case study from the Lower Cotter Catchment in south-eastern Australia. Key words: salvage harvesting, natural disturbance, environmental impacts, ecologically sustainable forestry, forest planning, long-term forest sustainability

scholarly journals Investment Priorities of France in Russia

2021 ◽  
Vol 21 (3) ◽  
pp. 128-136
Author(s):  
Egor Yumaev ◽  
Keyword(s):  
United States ◽  
Direct Investment ◽  
Large Scale ◽  
Economic Sanctions ◽  
The United States ◽  
Restricted Range ◽  
Russian Economy ◽  
Wide Range ◽  
Local Manufacturing

One of the main conditions for the Russian economy transition to growth rates above the global average is large-scale investment. The so-called «smart investments» are important for the accelerated economic development of Russia. Only a restricted range of states is a source of «smart investment». France is among them and it is a long-standing economic partner of Russia. French business implements long-term projects in Russia. After the economic sanctions being introduced, not a single company has left Russia; however, new investors do not come from France, and the operating investors evaluate the prospects for continuing work very carefully. As there is the economic sanctions mode, lending agencies in France, being afraid of losing their business in the United States, refuse to finance projects in Russia, even if they are not included into the sanctions list. Local manufacturing content of French companies still does not cover a wide range of areas in Russia, being limited mainly to agriculture. Compared to French, Russia’s investment contribution to France is disproportionately small. The article examines the factors determining the direct investment of France in Russia; the current investment agenda of French business in Russia; identifies the prospects for France’s investment participation in the Russian economy

scholarly journals Is scaling-up COVID-19 testing cost-saving?

2020 ◽  
Author(s):  
Bernardo Sousa-Pinto ◽  
João Almeida Fonseca ◽  
Altamiro Costa-Pereira ◽  
Francisco Nuno Rocha-Gonçalves
Keyword(s):  
Cost Saving ◽  
Large Scale ◽  
Scale Up ◽  
Scaling Up ◽  
World Health ◽  
Hospitalization Costs ◽  
Testing Cost ◽  
Additional Costs ◽  
Economic Analyses ◽  
Health Organization

The World Health Organization currently recommends that governments scale up testing for COVID-19 infection. We performed health economic analyses projecting whether the additional costs from screening would be offset by the avoided costs with hospitalizations. We analysed Portuguese COVID-19 data up until the 22nd March 2020, and estimated the additional number of cases that would be detected if different testing rates and frequencies of positive results would have been observed. We projected that, in most scenarios, the costs with scaling up COVID-19 tests would be lower than savings with hospitalization costs, rendering large scale testing cost-saving.

scholarly journals 9.G. Workshop: Evaluation of scale-up of health systems interventions: what and how? Lessons for scale-up projects

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
◽  
Keyword(s):  
Small Group ◽  
Health Information ◽  
Large Scale ◽  
Scale Up ◽  
Health Information Systems ◽  
Scaling Up ◽  
Evaluation Methods ◽  
Cost Evaluation ◽  
Research Projects ◽  
Implementation Evaluation

Abstract Objectives Non-communicable diseases (NCD) are a major challenge for health systems across the globe. Although effective interventions for prevention, detection and control exist, these do not reach all people in need, especially the poor and most vulnerable. Scale-up strategies are developed to increase universal access to those interventions, addressing demand-side and supply-side barriers and to facilitate integration in the health system. While there are useful frameworks to conceptualise and operationalise scale-up of NCD interventions, there is a knowledge gap on what and how to evaluate. This session addresses that knowledge gap, presenting evaluation methods for scale-up from four large multi-country research projects. The objectives are: To increase knowledge on four dimensions of scale-up evaluation: 1) contextualisation of methods; 2) implementation evaluation; 3) cost-evaluation and 4) use of health information systemsTo present methods and results of implementation research on NCDs as an example for other chronic diseasesTo illustrate how contextualisation, implementation and evaluation varies across different stages of scale-upTo stimulate learning by experience through small-group discussion with session participants This workshop provides added value through the four coherent presentations combined with small group interactions on the same topics. It allows the audience to link the case study lessons to their own research and wider application. Format Four different elements of scale-up evaluation are addressed: 1) Contextualisation of evaluation methods from a common framework; 2) Implementation evaluation at operational level; 3) Cost-evaluation of NCD interventions; and 4) Large-scale evaluation through routine health information systems (HIS). Case studies from four large-scale Horizon2020 funded research projects in 14 countries in Europe, Africa and Asia will be presented, each case focusing on one dimension. Cross-cutting themes of adaptation and transferability of methods will also be addressed. After the presentations, there will be an interactive session to promote experience-based learning in small-group discussions. Presentations Self-Management Approach and Reciprocal Learning for Type 2 Diabetes (SMART2D)Scaling-up Packages of Interventions for cardiovascular disease prevention in Europe and Sub-Saharan Africa (SPICES)Scaling-Up NCD Interventions in South-East Asia (SUNI-SEA)The Scale-Up of Diabetes and Hypertension Care (SCUBY) The presentations will provide the introduction to subsequent small-table discussions, around the following questions: How to measure and monitor implementation and outcome of intervention scale-up?How to generate transferrable lessons from cross-country studies?How to conduct cross-setting evaluation of the effect and cost of NCD interventions? Key messages The global scale-up of NCD interventions calls for robust evaluation methods of effect, implementation and cost. Evaluation methods need to be fit to the country context and health information systems.

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