scholarly journals Proton magnetic spectroscopy agreed better with magnetic resonance image to lateralization of epileptogenic zone than with surface electroencephalography

2013 ◽  
Vol 71 (9A) ◽  
pp. 584-590
Author(s):  
Ricardo Andre Amorim Leite ◽  
Maria Concepcion Garcia Otaduy ◽  
Gilson Edmar Goncalves e Silva ◽  
Maria Lucia Brito Ferreira ◽  
Maria de Fatima Vasco Aragao

Objective To analyze the agreement rate of proton magnetic spectroscopy with magnetic resonance image (MRI) and surface electroence-phalography (EEG) in extratemporal neocortical epilepsies. Methods A cross-sectional study, type series of cases included 33 patients, age range 13–59 years old, of both gender, presenting structural alteration identified by MRI (75.8%) or by neurophysiologic techniques (72.7%). The variables were alterations of N-acetyl-aspartate/choline, N-acetyl-aspartate/creatine, choline/creatine, and N-acetyl-aspartate/cho-line+creatine coefficient of asymmetry. Results Agreement rates of lateralization by coefficient of asymmetry of NAA/Cho, NAA/Cr, Co/Cr, and NAA/Cho+Cr with MRI, independent of alteration of surface EEG, were equal to 93.3, 57.9, 15.4, and 93.3%, respectively, modifying to 100, 33.3, 0, and 100%, in 16 patients, with lateralization agreement of MRI and surface EEG. Conclusion Proton magnetic spectroscopy agreed better with MRI to lateralization of epileptogenic zone than with surface EEG.

2020 ◽  
Vol 18 ◽  
Author(s):  
Kartik Gupta ◽  
Shivabalan ◽  
Virendra Kumar ◽  
Surabhi Vyas ◽  
RM Pandey ◽  
...  

Background: Cognitive impairment in patients with human immunodeficiency virus (HIV) is associated with higher morbidity. The prevalence of and the metabolite changes in the brain associated with cognitive impairment in anti-retroviral therapy naïve patients with HIV is unknown. Objective: To estimate the prevalence of, and the neurometabolites associated with cognitive impairment in antiretroviral therapy (ART) naïve patients with HIV. Methods: We conducted a cross-sectional study among ART naïve patients with HIV aged 18-50 years in a tertiary care center in India. Cognition was tested using the Post Graduate Institute battery of brain dysfunction across five domains; memory, attentioninformation processing, abstraction executive, complex perceptual, and simple motor skills. We assessed the total N-acetyl aspartyl (tNAA), creatine (tCr) and glutamate + glutamine (Glx) using 3T magnetic resonance spectroscopy. Cognitive impairment was defined as an impairment in ≥2 domains. Results: Among 43 patients eligible for this study, the median age was 32 years (IQR 29, 40) and 30% were women. Median CD4 count and viral load were 317 cells/µL (IQR 157, 456) and 9.3 copies/ µL (IQR 1.4, 38), respectively. Impairment in at least one cognitive domain was present in 32 patients (74.4%). Impairment in simple motor skills and memory was present in 46.5% and 44% of patients, respectively. Cognitive impairment, defined by impairment in ≥2 domains, was found in 22 (51.2%) patients. There was a trend towards higher concentration of tNAA (7.3 vs. 7.0 mmol/kg), tGlx (9.1 vs. 8.2 mmol/kg), and tCr (5.5 vs. 5.2 mmol/kg) in the frontal lobe of patients with cognitive impairment vs. without cognitive impairment but it did not reach statistical significance (p>0.05 for all). There was no difference in the concentration of these metabolites in the two groups in the basal ganglia. Conclusions: There is a high prevalence of cognitive impairment in ART naïve patients with HIV. There is no difference in metabolites in patients with or without cognitive impairment. Further studies, with longitudinal follow-up, are required to understand the underlying pathophysiological mechanisms.


Author(s):  
I. Sudoł-Szopińska ◽  
G. A. Santoro ◽  
M. Kołodziejczak ◽  
A. Wiaczek ◽  
U. Grossi

AbstractAnal fistula (AF) is a common referral to colorectal surgeons. Management remains challenging and sometimes controversial. Magnetic resonance imaging (MRI) is commonly performed in initial workup for AF. However, reports often lack key information for guiding treatment strategies. It has been shown that with structured radiology reports, there is less missing information. We present a structured MRI template report including 8 key descriptors of anal fistulas, whose effectiveness and acceptability are being assessed in a cross-sectional study (NCT04541238).


2021 ◽  
pp. 030157422110221
Author(s):  
Jyoti Mishra ◽  
Sudhir Kapoor ◽  
Jitendra Bhagchandani ◽  
Sonahita Agarwal ◽  
Vaibhav Vashishta ◽  
...  

Aim and Objective: To assess the level of awareness among local adult population (orthodontically untreated) regarding orthodontic treatment and procedures. Materials and Methods: A cross-sectional study was planned by accessing 100 subjects comprising of 2 groups (50 male and 50 female). After due ethical clearance, a self-structured questionnaire consisting of 17 questions was given to a group of randomly selected 100 individuals with an age range of 20 to 30 years. Results: The overall awareness of orthodontics as a speciality among both the groups was only 52% to 56%. Statistically insignificant difference was found in the knowledge and awareness of orthodontic treatment among both male and female subjects, that is, Group I and II. Also, those who knew about the orthodontic treatment did not opt for it because of high cost and longer duration involved. Conclusion: More than half of the population is unaware of the scope of orthodontic treatment, and thus, they do not seek any assistance. Hence, more efforts are needed to create awareness about orthodontics and the associated benefits.


2021 ◽  
Vol 14 (01) ◽  
pp. 011-015
Author(s):  
Rodrigo Fernandes Weyll Pimentel ◽  
Gilson Cruz de Moraes ◽  
Shalla Gomes Cavalcanti Barcelos ◽  
Pedro Carlos Muniz de Figueiredo ◽  
Magno Conceição Das Merces

Abstract Introduction The Coronavirus has spread to almost every country in the world, causing the coronavirus disease (COVID-19). The coronavirus stands out among the other infections especially by it's high contagious power and important effects on the respiratory system. The COVID-19 has differents ways of presentation and these are influenced by the patient's previous nutricional status, correlated with the patient's lifestyle and comorbities. Objective this survey seeks to analyze the nutritional status and the prevalence of obesity in patients hospitalized with SARS-CoV-2. Methods: this is a descriptive, prospective and cross-sectional study type, which 41 patients affected by COVID-19 were interviewed. Patient's weight and height were used to assess the BMI, and nutritional risk assessment was performed using the Nutritional Risk Screening tool (NRS 2002). For the analysis, Absolute (AF) and Relative Frequency (RF), the mean and the standard deviation were calculated. Results It was observerd that 78% of the participants had a high nutritional risk, while only 22% had a low nutritional risk. Besides that, 34% showed overweight and 41.4% showed obesity. Conclusion the existence of a high prevalence of increased nutritional risk was evidenced, in addition to the high frequency of overweight in patients affected by SARS-CoV-2.


2021 ◽  
Vol 8 (26) ◽  
pp. 2253-2259
Author(s):  
Mohit B. Gor ◽  
Kuldeepsinh D. Mori ◽  
Mehul N. Bavishi ◽  
Nirmala C. Chudasama ◽  
Jaypalsinh D. Barad ◽  
...  

BACKGROUND Brain tumours represents 1.7 % of all cancers and contributes 1.8 % of all cancer deaths. Of all the brain tumours, 80 % are supratentorial.1 Magnetic resonance imaging (MRI) is an important modality, having higher sensitivity for detecting intracranial pathology. Multiplanar imaging is possible with MRI which helps in detection, localization and characterization of the lesion. MRI examination has helped in early diagnosis, accurate localization of the tumour, with prompt initiation of appropriate medical or surgical therapy. Recent advances like magnetic resonance (MR) spectroscopy, MR fluoroscopy with stereotactic guided biopsy have revolutionized the role of MRI in study of intracranial tumours. METHODS A cross sectional study of 75 patients was done by Siemens Essenza 1.5T MRI from June 2018 to June 2020 using dedicated head coil. RESULTS In our study, most of the patients were between 31 - 60 years of age (39 % of all patients) with the largest group between 31 - 40 years (20 % of all patients). Out of 75 cases of supratentorial neoplasms, 47 (72 %) were intra-axial lesions, 15 (23 %) were extra-axial lesions and 3 (5 %) were intra ventricular lesions. In this study, 69 % of the lesions were solitary and 31 % were multiple. Most of patients (89 %) showed some enhancement, most common being heterogeneous/inhomogeneous enhancement. Commonest type of supratentorial neoplasms were metastases comprising 29 % of this study. CONCLUSIONS Magnetic resonance imaging is an important modality, having higher sensitivity for detecting intracranial pathology. Multiplanar imaging is possible with MRI which helps in early detection, localization and characterization of the lesion. Metastasis is the most common supratentorial tumour in this study followed by meningioma. Intra-axial tumours are more common than extra-axial tumours in this study. KEYWORDS MRI, Metastasis, Glioma, Meningioma


2016 ◽  
Vol 32 (2) ◽  
pp. 609 ◽  
Author(s):  
Olga Hernández-Serrano ◽  
José P. Espada ◽  
Alejandro Guillén-Riquelme

<p>The objectives of the present study are the following ones: 1) to study the use of drugs, the prosocial behaviour and the problem-solving skills with respect to age and gender, and 2) to analyze the association of both the prosocial behaviour and the problem-solving skills with the use of drugs. An exploratory cross-sectional study was performed, amongst a sample of 567 students in Spanish Compulsory Secondary Education (48.14% males) with an age range from 14 to 17 years (<em>M </em>= 14.92; <em>SD </em>= 0.90). Statistically significant differences were found concerning alcohol use and the prosocial behaviour with respect to gender, as well as concerning alcohol and cannabis use with respect to age. Logistic regression analyses revealed statistical significance of the prosocial behaviour with respect to the use of alcohol and cannabis. The ability in problem-solving was the most important protective predictor with respect to the abuse of cannabis. The results from this study enhance the importance of tailored interventions based on the promotion of prosocial behaviours and/or problem-solving strategies as fundamental protective factors for substance use amongst adolescents.</p>


Author(s):  
T Nasreen ◽  
ME Haq

In the management of the adult dental patient efforts are geared towards the preservation of permanent dentition as it is important for maintaining normal occlusal relationship, play role in aesthesis, speech, influence food habit and nutrition. This hospital based descriptive type of cross sectional study was done at Exodontia Department of Dhaka Dental College and Hospital to identify the factors that contribute in tooth extraction among the respondents. The study was carried out during the month of January to June 2009 and 110 respondents selected purposively. The study showed the majority of the respondents (57.3%) were in the age group of 20-39 years. Their mean age was 36.85.years, SD of age was ±13.85 and age range was 15-85 years. Among the respondents 46.4% were male and 53.6% were female. Dental caries was the leading cause of tooth extractions in 68% cases. It was also observed that post filling complication contributed in 33% cases of extraction. Patient requests due to economic cause in 16% cases, negligence in 11% cases and even distance of the treatment centre from residence reported in 15% cases. The treatment philosophy of the centre played a vital role. Heavy rush of the patient and inconvenient conservative treatment schedule caused many unnecessary extractions DOI: http://dx.doi.org/10.3329/bjodfo.v2i1.15996 Ban J Orthod & Dentofac Orthop, October 2011; Vol-2, No.1, 7-10


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