Comparison Of Full-Mouth Scaling and Quadrant-Wise Scaling in the Treatment of Adult Chronic Periodontitis

Abstract In the search for the ideal treatment of periodontal disease various non-surgical techniques should be considered. The objective of this study was to evaluate the efficacy of full-mouth scaling (FMS) by clinical and microbiological parameters. 670 individuals were evaluated with 230 subjects meeting the selection criteria and were divided into two groups; 115 subjects treated with FMS and 115 treated with weekly sessions of scaling and root planning (SRP). The patient population had a mean age of 51.67 years, with moderate chronic periodontitis. Subjects were evaluated prior to treatment (T1) and 90 days after execution of therapy (T2), with regards to: probing depth (PD), clinical attachment level (CAL), plaque index (PI), gingival index (GI), and microbial detection for the presence of Porphyromonas gingivalis (P.g.) and Prevotella intermedia (P.i.) by culture method and confirmed by biochemical tests. Subjects treated in the FMS group also rinsed with 0.12% chlorhexidine mouthwash for seven days following treatment. The results were analyzed using statistical Student’s t-test and chi-square test. No statistically significant differences were observed for PD and CAL between T1 and T2 in both groups. For GI and PI significant difference was observed between the groups. For the evaluated microbial parameters was observed reduction of P.g. and P.i., but only for P.g. with a significant reduction in both groups. The full mouth scaling technique with the methodology used in this study provided improved clinical conditions and reduction of P.g. in subjects with moderate periodontitis, optimizing the time spent in the therapeutic execution.

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Incidence of adverse drug reactions induced by N-acetylcysteine in patients with acetaminophen overdose

Human & Experimental Toxicology ◽

10.1177/0960327109359642 ◽

2010 ◽

Vol 29 (3) ◽

pp. 153-160 ◽

Cited By ~ 18

Author(s):

Sa'ed H Zyoud ◽

Rahmat Awang ◽

Syed Azhar Syed Sulaiman ◽

Waleed M Sweileh ◽

Samah W Al-jabi

Keyword(s):

Adverse Drug Reactions ◽

Univariate Analysis ◽

Drug Reactions ◽

Chi Square ◽

Exact Test ◽

Acetaminophen Overdose ◽

Significant Difference ◽

Chi Square Test ◽

Comparative Results ◽

Student’S T

Background: Intravenous N-acetylcysteine (IV-NAC) is widely recognized as the antidote of choice for acetaminophen overdose. However, its use is not without adverse drug reactions (ADR) that might affect therapeutic outcome or lead to treatment delay. Objective: the aim of this study was to investigate the type and incidence of ADR induced by IV-NAC in patients treated for acetaminophen overdose. Methods: This is a retrospective study of patients admitted to the hospital for acute acetaminophen overdose over a period of 4 years (1 January 2005 to 31 December 2008). The primary outcome of interest in this study was the occurrence of ADR during NAC administration. Pearson chi-square test or Fisher’s exact test, student’s t test, and Mann-Whitney U test were used in univariate analysis. SPSS 15 was used for data analysis. Results: Two hundred and fifty five patients were studied. Different types of ADR were observed in 119 (46.7%) cases. Of those patients, 83 (69.7%) had been treated with IV-NAC versus 36 (30.3%) who had not (p < .001). The following ADR were significantly associated with IV-NAC administration: vomiting (p = .001), flushing (p < .001), rash (p < .001), pruritus (p < .001), chest pain (p = .001), bronchospasm (p = .03), coughing (p = .01), headache (p = .001), dizziness (p < .001), convulsion (p = .03), and hypotension (p = .001). ADR were mild in 54 (43.2%), moderate in 17 (13.6%), and severe in 12 (9.6%) patients. There were no ADR in 42 (33.6%) patients. Comparative results of the characteristics of patients who reacted to IV-NAC and nonreactors showed that patients with ADR had no significant difference in age, gender, ethnicity, amount ingested, latency time, and acetaminophen level than nonreactors. Conclusion: ADR to IV-NAC were common among patients with acetaminophen overdose, but mostly minor and all reported adverse reactions were easily managed.

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Assessment of first molars sagittal and rotational position in Class II, division 1 malocclusion

Dental Press Journal of Orthodontics ◽

10.1590/s2176-94512013000600016 ◽

2013 ◽

Vol 18 (6) ◽

pp. 106-111 ◽

Cited By ~ 1

Author(s):

Paulo Estevão Scanavini ◽

Renata Pilli Jóias ◽

Maria Helena Ferreira Vasconcelos ◽

Marco Antonio Scanavini ◽

Luiz Renato Paranhos

Keyword(s):

Class Ii ◽

Chi Square ◽

Mean Values ◽

Significance Level ◽

Significant Difference ◽

Division 1 ◽

Chi Square Test ◽

Student’S T ◽

The Right ◽

Class Ii Division 1

OBJECTIVE: This study assessed the anterior-posterior positioning of the upper and lower first molars, and the degree of rotation of the upper first molars in individuals with Class II, division 1, malocclusion. METHODS: Asymmetry I, an accurate device, was used to assess sixty sets of dental casts from 27 females and 33 males, aged between 12 and 21 years old, with bilateral Class II, division 1. The sagittal position of the molars was determined by positioning the casts onto the device, considering the midpalatal suture as a symmetry reference, and then measuring the distance between the mesial marginal ridge of the most distal molar and the mesial marginal ridge of its counterpart. With regard to the degree of rotation of the upper molar, the distance between landmarks on the mesial marginal ridge was measured. Chi-square test with a 5% significance level was used to verify the variation in molars position. Student's t test at 5% significance was used for statistical analysis. RESULTS: A great number of lower molars mesially positioned was registered, and the comparison between the right and left sides also demonstrated a higher number of mesially positioned molars on the right side of both arches. The average rotation of the molars was found to be 0.76 mm and 0.93 mm for the right and left sides, respectively. CONCLUSION: No statistically significant difference was detected between the mean values of molars mesialization regardless of the side and arch. Molars rotation, measured in millimeters, represented ¼ of Class II.

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Effect of Use of Ambulance as Emergency Medical Service in Patients of ST-Elevation Myocardial Infarction

Life and Science ◽

10.37185/lns.1.1.189 ◽

2021 ◽

Vol 2 (3) ◽

pp. 4

Author(s):

Majid Bashir ◽

Kubra Maryam ◽

Nazeer Ahmed ◽

Tariq Mehmood ◽

Adnan Aslam

Keyword(s):

Myocardial Infarction ◽

St Elevation Myocardial Infarction ◽

Base Line ◽

Chi Square ◽

Level Of Satisfaction ◽

Significant Difference ◽

Chi Square Test ◽

St Elevation ◽

Student’S T ◽

Student’S T Test

Objective: To study the frequency of ambulance utilization by the St-elevation Myocardial Infarction patients toreach hospital, perception of ambulance users about the facilities available in the ambulance, and evaluate theclinical outcomes of STEMI between ambulance users and non-users.Study Design: Cross-section survey-based study.Place and Duration of Study: The study was carried out in the Department of Cardiology at Chaudry Pervaizth th Elahi Institute of Cardiology (CPEIC) Multan from 14 April 2020 to 14 September 2020.Materials and Methods: Patients with the diagnosis of STEMI were included in the study and were classifiedinto two groups' ambulance and non-ambulance users, to reach the facility. Patients' demographics, initialpresenting symptoms, availability of ambulance, and time to reach the hospital were recorded. Moreover, theywere followed for complication during their stay and base line laboratory indicators. Ambulance users werealso evaluated for their perception about availability of medical services in the ambulance. The data collectedfrom both of the groups were compared through student's t-test and chi-square test. Statistical value less than0.05 was considered as significant.Results: Out of 300 patients, 32.6% were ambulance users while 67.4% were non-ambulance user. Nosignificant difference was found in age, gender, underlying comorbidity, and initial presenting symptomsbetween two groups. Majority of ambulance users (74%) arrived in less than 45minutes. Differentcomplications were recorded but no significant difference was found between two groups. Majority ofambulance users 31.5% were neutral about the level of satisfaction for ambulance facilities.Conclusion: Frequency of ambulance utilization by STEMI patients is not only low in Pakistan, but ambulancesystem is also not successful in producing significant change in clinical outcomes. Therefore an awarenesscampaign along with ambulance improvement campaigns should be launched to bring a meaningful change.

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135 SHORT-TERM CRYOPRESERVATION OF VITRIFIED MOUSE MORULAE AT - 79°C

Reproduction Fertility and Development ◽

10.1071/rdv19n1ab135 ◽

2007 ◽

Vol 19 (1) ◽

pp. 185

Author(s):

Y. Takagi ◽

M. Shimizu ◽

M. Morimura ◽

S. Yokomizo ◽

K. Hara ◽

...

Keyword(s):

Liquid Nitrogen ◽

Blastocyst Stage ◽

Control Group ◽

Embryo Viability ◽

Chi Square ◽

Significant Difference ◽

Morula Stage ◽

Chi Square Test ◽

Student’S T

Embryos of various species are successfully vitrified and cryopreserved in liquid nitrogen (<−150°C). Like the preservation of frozen somatic cells cooled by dry ice (−79°C), the cryopreservation of embryos at −79°C is useful for a reduction in the shipping costs. The purpose of this study was to evaluate the effect of the cryopreservation period at −79°C on the in vitro embryo viability of vitrified mouse morulae after thawing. Morula-stage mouse embryos were collected from superovulated ICR donors 70 h after hCG injection. The embryos were exposed first to 5% DMSO + 5% ethylene glycol (EG) in Dulbecco's PBS + 20% FCS (mPBS) for 2 min, and then equilibrated for 20–30 s in a vitrification solution composed of 10% DMSO + 10% EG + 0.6 M sucrose in mPBS. The embryos were loaded onto cryoloops (Lane et al. 1999 Nat. Biotech. 17, 1234–1236) and plunged directly into liquid nitrogen. The cryoloops were placed in 1.2-mL cryotubes and stored in a −79°C freezer for 1–7 days. The embryos were warmed by passing through 4 dilution media and rinsed with mWM culture medium. They were then cultured at 37°C in 5% CO2 for 44 h. Non-cryopreserved embryos and embryos cryopreserved in liquid nitrogen served as controls. Data were analyzed by the chi-square test and the Student's t-test. Results are shown in Table 1. There was no significant difference (P > 0.01) in the developmental abilities to the blastocyst stage of the vitrified embryos that were cryopreserved at −79°C for 1 day, 3 days, and 5 days, the embryos cryopreserved in liquid nitrogen, and the non-vitrified control. The blastocyst rate of embryos was significantly lower (P < 0.01) for the Day 7 group than for the control group. The cell numbers of blastocysts were significantly lower (P < 0.01) for the Day 1, Day 3, Day 5, and Day 7 groups than for the control group. This study suggests that vitrified mouse morulae can be successfully cryopreserved at −79°C for 5 days. Table 1. Effect of the cryopreservation period on the viability of vitrified mouse morulae preserved at −79°C

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Therapeutic potential of Brazilian fluoride varnishes: an in vivo study

Brazilian Dental Journal ◽

10.1590/s0103-64402011000300003 ◽

2011 ◽

Vol 22 (3) ◽

pp. 193-197 ◽

Cited By ~ 5

Author(s):

Marcella Quirino de Almeida ◽

Olívia Ximenes Izidro Costa ◽

Jainara Maria Soares Ferreira ◽

Valdenice Aparecida de Menezes ◽

Rossana Barbosa Leal ◽

...

Keyword(s):

Therapeutic Potential ◽

Clinical Results ◽

White Spot Lesions ◽

Final Size ◽

Chi Square ◽

Anterior Teeth ◽

Significant Difference ◽

Chi Square Test ◽

Student’S T

The aim of this study was to assess in vivo the therapeutic effect of three fluoride varnishes available in the Brazilian market on the performance of white spot lesions (WSL). The sample included 36 children aged 7 to 13 years old, with a total of 67 active WSL in permanent anterior teeth. The children were randomly divided into 3 groups, according to fluoride varnish used: FL- Fluorniz (n=24), DUO - Duofluorid XII (n=22) and DF - Durafluor (n=21). Maximum WSL dimensions (mesiodistal and incisogingival) were measured in millimeters by a previously calibrated single examiner using a periodontal probe. WSL were also assessed regarding lesion activity. Initial and final S-OHI (Simplified Oral Hygiene Index) scores were recorded. Pearson's chi-square test revealed no statistically significant differences (p>0.05) in the performance of the varnishes. At the end of the 5th week, FL had 6 active and 18 inactive WSL; DUO had 7 active and 15 inactive WSL; and DL had 6 active and 15 inactive WSL. Taking into account all lesions, there was a 45.7% reduction in WSL dimensions. Paired Student's t-test revealed a statistically significant difference (p<0.05) between the initial size (1.88) and final size (1.02). After four applications, all varnishes obtained similar clinical results.

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The evolution of neuropsychiatric symptoms during treatment for hyperthyroidism

Romanian Journal of Medical Practice ◽

10.37897/rjmp.2021.2.27 ◽

2021 ◽

Vol 16 (2) ◽

pp. 273-278

Author(s):

Oana-Maria NICOLA (MARIOARA) ◽

◽

Alice Elena GHENEA ◽

Cristina-Nicoleta VLĂDOIANU ◽

Valentin CARLIG ◽

...

Keyword(s):

Neuropsychiatric Symptoms ◽

Antithyroid Drug ◽

T Test ◽

Chi Square ◽

Antithyroid Drug Therapy ◽

Significant Difference ◽

Hamd Score ◽

Chi Square Test ◽

Student’S T ◽

Student’S T Test

Introduction. The link between the action of thyroid hormones and neurological, cognitive and affective function is well known. The aim of the study is to evaluate the changes of hormone’s value and symptoms at hyperthyroid patients after 6 months and 1 year of treatment. Materials and methods. In our study, we enrolled 80 patients with hyperthyroidism (new cases) and we asked them to fill out a questionnaire three times: first time was when they were into a thyrotoxic state (before the antithyroid drug therapy – ATD) and after that during ATD treatment (when they were into an euthyroid state after 6-12 months of treatment, average 7 months). Results. There is no statistically significant difference between the ages of the study and control groups (p Student’s t -test = 0.207 > 0.005), nor between the distributions according to gender (p Chi square test = 0.827) or area of residence (p Chi square test = 0.820). For HAMD score, there is highly significant differences (p < 0.001) before treatment, a statistically significant difference after 6 months (p Student’s t-test = 0.015 < 0.05), and no statistically significant difference after 1 year. Conclusion. Depression and anxiety were improved following thyroid function normalization in hyperthyroidism.

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The Influence of Age and Gender on Mandibular Indices among the Libyan Population

Journal of Oral & Dental Health ◽

10.33140/jodh.03.02.2 ◽

2019 ◽

Vol 3 (2) ◽

Keyword(s):

Negative Correlation ◽

Bone Mineralization ◽

Age Groups ◽

T Test ◽

Chi Square ◽

Age And Gender ◽

Significant Difference ◽

Chi Square Test ◽

And Gender ◽

Libyan Population

Radiographic Mandibular Indices serve as easy and relatively cheap tools for evaluating bone mineralization. Objectives: To examine the effect of age and gender on three mandibular indices: the panoramic mandibular index (PMI), the mandibular ratio (MR) and the mandibular cortical index (MCI), among Libyan population. Methods: The three indices were measured on 317 digital (OPGs) of adult humans (155 males, 162 females). The sample was divided into six age groups (from 18-25 years through 56-65 years). The measurements were analyzed for interactions with age and sex, using SPSS (Statistical Package for Social Studies) software version no. 22. The tests employed were two way ANOVA, the unpaired T-test and chi-square test. Results: The mean PMI fluctuated between 0.37 s.d. 0.012 and 0.38 s.d. 0.012. among the sixth age groups. One-way ANOVA statistical test revealed no significant of age on PMI. On the other hand gender variation has effect on PMI, since independent sample t-test disclosed that the difference between the male and female PMI means statistically significant. ANOVA test showed that the means of MR among age groups showed a negative correlation i.e. MR mean declined from 3.01 in 18-25 age groups to 2.7 in 55-65 age groups. In contrary, the gender showed no effect on MR according two sample t-test at p> 0.05. In regards with MCI, statistical analysis showed that it affected by age that is C1 was decreasing by age while C2 and C3 were increased by age. Using chi square test the result indicated that there is a significant difference among the different age group and the two genders in MCI readings. Conclusion: PMI was influenced significantly by age but minimally by the gender. MR is not affected by gender but has a negative correlation with age. MCI is affected by both age and gender

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Prognostic significance of peritoneal cytology in low-risk endometrial cancer: comparison of laparoscopic surgery and laparotomy

International Journal of Clinical Oncology ◽

10.1007/s10147-020-01854-z ◽

2021 ◽

Author(s):

Satoe Fujiwara ◽

Ruri Nishie ◽

Shoko Ueda ◽

Syunsuke Miyamoto ◽

Shinichi Terada ◽

...

Keyword(s):

Endometrial Cancer ◽

Laparoscopic Surgery ◽

Retrospective Study ◽

Prognostic Significance ◽

Low Risk ◽

Peritoneal Cytology ◽

Chi Square ◽

Significant Difference ◽

Chi Square Test ◽

Positive Peritoneal Cytology

Abstract Background There is uncertainty surrounding the prognostic value of peritoneal cytology in low-risk endometrial cancer, especially in laparoscopic surgery. The objective of this retrospective study is to determine the prognostic significance of positive peritoneal cytology among patients with low-risk endometrial cancer and to compare it between laparoscopic surgery and conventional laparotomy. Methods From August 2008 to December 2019, all cases of pathologically confirmed stage IA grade 1 or 2 endometrial cancer were reviewed at Osaka Medical College. Statistical analyses used the Chi-square test and the Kaplan–Meier log rank. Results A total of 478 patients were identified: 438 with negative peritoneal cytology (232 who underwent laparotomy and 206 who undertook laparoscopic surgery) and 40 with positive peritoneal cytology (20 who underwent laparotomy and 20 who received laparoscopic surgery). Survival was significantly worse among patients with positive peritoneal cytology compared to patients with negative peritoneal cytology. However, there was no significant difference among patients with negative or positive peritoneal cytology between laparoscopic surgery and laparotomy. Conclusion This retrospective study suggests that, while peritoneal cytology is an independent risk factor in patients with low-risk endometrial cancer, laparoscopic surgery does not influence the survival outcome when compared to laparotomy.

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A Randomized, Controlled, Parallel-Group, Trial on the Effects of Melatonin on Fatigue Associated with Breast Cancer and Its Adjuvant Treatments

Integrative Cancer Therapies ◽

10.1177/1534735420988343 ◽

2021 ◽

Vol 20 ◽

pp. 153473542098834

Author(s):

Abdolazim Sedighi Pashaki ◽

Kamal Mohammadian ◽

Saeid Afshar ◽

Mohammad Hadi Gholami ◽

Abbas Moradi ◽

...

Keyword(s):

Breast Cancer ◽

Adjuvant Chemotherapy ◽

Intervention Group ◽

Chi Square ◽

Significance Level ◽

Severe Fatigue ◽

Before And After ◽

Brief Fatigue Inventory ◽

Chi Square Test ◽

Student’S T

Objective: Fatigue associated with malignant conditions and their treatments is a disabling condition. This trial assessed the anti-fatigue effects of melatonin coadministration during adjuvant treatment of patients with the breast cancer. Material and Methods: Patients with breast cancer were randomly assigned to receive melatonin or placebo during adjuvant chemotherapy and radiotherapy. Thirty-seven patients were randomly enrolled in each group. The mean ages of patients in the intervention and control groups were 50.47 ± 10.79 and 46.05 ± 10.55 years, respectively ( P = .223). The intervention group received oral melatonin (18 mg/day) from 1 week before until 1 month after the adjuvant radiotherapy. The level of fatigue was assessed before and after intervention using Brief Fatigue Inventory (BFI) in both groups. To analyze data, the Student’s t-test and the Chi-square test were used at a significance level of P ≤ .05. Results: The BFI score was similar before the intervention in both groups, however, after the intervention, it was significantly lower in the melatonin group ( P < .001). Moreover, the frequency of severe fatigue in the melatonin group was significantly lower than in the placebo group after intervention (42.1% vs 83.3%, P < .001). Conclusion: Coadministration of melatonin during adjuvant chemotherapy and radiotherapy of women with breast cancer decreased the levels of fatigue associated with the malignant condition and its treatments.

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Effect of corneal refractive surgery on accommodative and binocular dysfunctions among civilian pilots in Southwest China

BMC Ophthalmology ◽

10.1186/s12886-021-01855-0 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Ye Wu ◽

Zhen Zhang ◽

Meng Liao ◽

Qi Li ◽

Xue Lin Tang ◽

...

Keyword(s):

Binocular Vision ◽

Refractive Surgery ◽

Visual Symptom ◽

Chi Square ◽

Visual Symptoms ◽

Significant Difference ◽

Symptom Scores ◽

Chi Square Test ◽

Corneal Refractive Surgery ◽

Normal Binocular Vision

Abstract Background To analyze whether corneal refractive surgery (CRS) is associated with the distribution of different accommodative dysfunctions (ADs) and binocular dysfunctions (BDs) in civilian pilots. A further aim was to analyze the percentages and visual symptoms associated with ADs and/or BDs in this population. Methods One hundred and eight civilian pilots who underwent CRS from January 2001 to July 2012 (age: 30.33 ± 4.60 years) were enrolled, the mean preoperative SE was − 1.51 ± 1.15 D (range: − 1.00- − 5.00 D). Ninety-nine emmetropic civilian pilots (age: 29.64 ± 3.77 years) who were age- and sex-matched to the CRS group were also enrolled. Refractive status, accommodative and binocular tests of each subject were performed. Visually related symptoms were quantified using the 19-item College of Optometrists in Vision Development Quality of Life (COVD-QOL) questionnaire. The 19 items were summed to obtain visual symptom scores that might indicate visual dysfunctions. The chi-square test was used to analyze differences in percentages of ADs and/or BDs between the CRS and emmetropic groups. The Mann-Whitney U test was used to compare visual symptom scores between pilots with ADs and/or BDs and pilots with normal binocular vision. Results No significant difference was observed between the CRS and emmetropic groups in the overall prevalence of ADs and BDs (15.7% and 15.2% in the CRS and emmetropic groups, respectively; P = 0.185). ADs were present in 4.63% and 3.03% of the CRS and emmetropic group, respectively. BDs were observed in 11.1% and 12.1% of the CRS and emmetropic group, respectively, yielding no significant differences between the groups in the prevalence of ADs or BDs (AD: P = 0.094; BD: P = 0.105). Pilots with ADs and/or BDs had significantly more visual symptoms than pilots with normal binocular vision (p < 0.001). Conclusions CRS for civilian pilots with low-moderate myopia might not impact binocular functions. ADs and/or BDs commonly occur in both emmetropia pilots and pilots who undergo CRS, and pilots with ADs and/or BDs are associated with increased symptoms. This study confirms the importance of a full assessment of binocular visual functions in detecting and remedying these dysfunctions in this specific population.

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