scholarly journals THE EMPEROR AS A 'MAN OF GOD': THE IMPACT OF CONSTANTINE THE GREAT'S. Conversion on Roman Ideas of Kingship

2016 ◽  
Vol 35 (0) ◽  
Author(s):  
Harold DRAKE
Keyword(s):  
Divine Intervention ◽  
The Cross ◽  
The Impact ◽  
Eusebius Of Caesarea

ABSTRACT In numerous ways, the first Christian emperor, Constantine I (r. 306-337) indicated that he saw parallels between himself and St. Paul. These include his story of divine intervention (the vision of the Cross) and his decision to be buried amid markers for the twelve Apostles. But his biographer, Bishop Eusebius of Caesarea, chooses to liken Constantine instead to Moses, who led the Israelites out of captivity. By focusing on the different connotation of "Man of God" (Constantine's preferred label for himself) and "Friend of God" (the phrase Eusebius used), this article suggests that the reason for this difference lay in Eusebius's concern to prevent Constantine - and by extension all future emperors - from asserting priority over Christian bishops.

scholarly journals Investigation of the functional network modifier loading on the stoichiometric ratio of epoxy resins and their dielectric properties

2021 ◽  
Author(s):  
Istebreq A. Saeedi ◽  
Sunny Chaudhary ◽  
Thomas Andritsch ◽  
Alun S. Vaughan
Keyword(s):  
Glass Transition ◽  
Dielectric Properties ◽  
Electrical Properties ◽  
Epoxy Resins ◽  
Functional Network ◽  
Cross Linking ◽  
Network Modifier ◽  
Epoxy Resin System ◽  
The Cross ◽  
The Impact

AbstractReactive molecular additives have often been employed to tailor the mechanical properties of epoxy resins. In addition, several studies have reported improved electrical properties in such systems, where the network architecture and included function groups have been modified through the use of so-called functional network modifier (FNM) molecules. The study reported here set out to investigate the effect of a glycidyl polyhedral oligomeric silsesquioxane (GPOSS) FNM on the cross-linking reactions, glass transition, breakdown strength and dielectric properties of an amine-cured epoxy resin system. Since many previous studies have considered POSS to act as an inorganic filler, a key aim was to consider the impact of GPOSS addition on the stoichiometry of curing. Fourier transform infrared spectroscopy revealed significant changes in the cross-linking reactions that occur if appropriate stoichiometric compensation is not made for the additional epoxide groups present on the GPOSS. These changes, in concert with the direct effect of the GPOSS itself, influence the glass transition temperature, dielectric breakdown behaviour and dielectric response of the system. Specifically, the work shows that the inclusion of GPOSS can result in beneficial changes in electrical properties, but that these gains are easily lost if consequential changes in the matrix polymer are not appropriately counteracted. Nevertheless, if the system is appropriately optimized, materials with pronounced improvements in technologically important characteristics can be designed.

Are neutrophil extracellular traps the link for the cross-talk between periodontitis and rheumatoid arthritis physiopathology?

Rheumatology ◽  
2021 ◽  
Author(s):  
Sicília Rezende Oliveira ◽  
José Alcides A de Arruda ◽  
Ayda Henriques Schneider ◽  
Valessa Florindo Carvalho ◽  
Caio Machado ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Cross Talk ◽  
Neutrophil Extracellular Traps ◽  
Periodontal Therapy ◽  
Clinical Parameters ◽  
Extracellular Traps ◽  
Early Ra ◽  
The Cross ◽  
High Concentrations ◽  
The Impact

Abstract Objectives Neutrophil extracellular traps (NETs) play a role in the pathogenesis of periodontitis and rheumatoid arthritis (RA). However, it remains poorly understood whether NETs participate in the cross-talk between periodontitis and RA. Herein, we investigated the production of NETs in individuals with periodontitis and RA and its association with clinical parameters. The impact of periodontal therapy on RA and NET release was also assessed. Methods The concentration of NETs and cytokines was determined in the saliva and plasma of individuals with early RA (n = 24), established RA (n = 64), and individuals without RA (n = 76). The influence of periodontitis on the production of NETs and cytokines was also evaluated. Results Individuals with early RA had a higher concentration of NETs in saliva and plasma than individuals with established RA or without RA. Periodontitis resulted in an increase in the concentration of NETs of groups of individuals without RA and with early RA. The proportion of individuals with high concentrations of IL-6, IL-10 and GM-CSF was higher among individuals with periodontitis than among individuals without periodontitis. The concentrations of TNF-α, IL-6, IL-17/IL-25, and IL-28A were particularly high in individuals with early RA. Worse periodontal clinical parameters, RA onset and RA activity were significantly associated with circulating NETs. Periodontal therapy was associated with a reduction in the concentration of NETs and inflammatory cytokines and amelioration in periodontitis and RA. Conclusion This study reveals that NETs are a possible link between periodontitis and RA, with periodontal therapy resulting in a dramatic switch in circulating NET levels.

SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies

2021 ◽  
Vol 22 ◽  
Author(s):  
Poornima Gopi ◽  
TR Anju ◽  
Vinod Soman Pillai ◽  
Mohanan Veettil
Keyword(s):  
Virus Infection ◽  
Host Cell ◽  
Metabolic Pathways ◽  
Inflammatory Responses ◽  
Membrane Lipid ◽  
Therapeutic Strategies ◽  
Metabolic Reprogramming ◽  
Multiple Organs ◽  
The Cross ◽  
The Impact

: Novel coronavirus, SARS-CoV-2 is advancing at a staggering pace to devastate the health care system and foster the concerns over public health. In contrast to the past outbreaks, coronaviruses aren’t clinging themselves as a strict respiratory virus. Rather, becoming a multifaceted virus, it affects multiple organs by interrupting a number of metabolic pathways leading to significant rates of morbidity and mortality. Following infection they rigorously reprogram multiple metabolic pathways of glucose, lipid, protein, nucleic acid and their metabolites to extract adequate energy and carbon skeletons required for their existence and further molecular constructions inside a host cell. Although the mechanism of these alterations are yet to be known, the impact of these reprogramming is reflected in the hyper inflammatory responses, so called cytokine storm and the hindrance of host immune defence system. The metabolic reprogramming during SARS-CoV-2 infection needs to be considered while devising therapeutic strategies to combat the disease and its further complication. The inhibitors of cholesterol and phospholipids synthesis and cell membrane lipid raft of the host cell can, to a great extent, control the viral load and further infection. Depletion of energy source by inhibiting the activation of glycolytic and hexoseamine biosynthetic pathway can also augment the antiviral therapy. The cross talk between these pathways also necessitates the inhibition of amino acid catabolism and tryptophan metabolism. A combinatorial strategy which can address the cross talks between the metabolic pathways might be more effective than a single approach and the infection stage and timing of therapy will also influence the effectiveness of the antiviral approach. We herein focus on the different metabolic alterations during the course of virus infection that help to exploit the cellular machinery and devise a therapeutic strategy which promotes resistance to viral infection and can augment body’s antivirulence mechanisms. This review may cast the light into the possibilities of targeting altered metabolic pathways to defend virus infection in a new perspective.

scholarly journals PERAYAAN EKARISTI SEBAGAI SUMBER DAN PUNCAK SELURUH HIDUP KRISTIANI

2020 ◽  
Vol 20 (1) ◽  
pp. 88-100
Author(s):  
Don Bosco Karnan Ardijanto
Keyword(s):  
Christian Life ◽  
Daily Lives ◽  
In Christ ◽  
The Cross ◽  
The Impact ◽  
The Church

The Eucharist is the source and summit of the Christian life. Many faithful celebrate the Eucharist: some experience the Eucharist's impact, but many do not feel the impact of the Eucharist on their daily lives. The Eucharist is the memory of Christ's sacrifice on the cross. He himself is present at the Eucharist. Therefore the Eucharist is a source of grace and blessing to the lives of the faithful: to bring the fruits of redemption and to be the source of life for the faithful; building–living–reviving the Church. The Eucharist is also a source of repentance and forgiveness as well as a source for developing faith, hope, and love. The Eucharist is the offering of Christ and His Church. Therefore, in the Eucharist the faithful offer their entire lives to be transformed into a source of life and blessing for them and the whole world. In the spirit of repentance, the faithful are also called to offer themselves in faith, hope and love. Celebrating the Eucharist and seriously believing its truths will illuminate the daily lives of the faithful and grow in love for the Eucharist, so that they grow in love for God and others in Christ.

scholarly journals Experimental and Numerical Study on Ultimate Shear Load Carrying Capacity of Corroded RC Beams

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Zhanzhan Tang ◽  
Zhixiang He ◽  
Zheng Chen ◽  
Lingkun Chen ◽  
Hanyang Xue ◽  
...  
Keyword(s):  
Shear Strength ◽  
Bearing Capacity ◽  
Cross Section ◽  
Loss Rate ◽  
Numerical Study ◽  
Rc Beams ◽  
Load Carrying ◽  
Shear Bearing Capacity ◽  
The Cross ◽  
The Impact

For an RC beam, the strength of steel rebar, the bonding strength between the concrete and reinforcement, and the bite action between the aggregates will deteriorate significantly due to corrosion. In the present study, 10 RC beams were designed to study the impact of corrosion on the shear bearing capacity. The mechanism of corrosion for stirrups and longitudinal bars and their effects were analyzed. Based on the existing experimental data, the correlation between the stirrup corrosion factor and the cross section loss rate was obtained. An effective prediction formula on the shear bearing capacity of the corroded RC beams was proposed and validated by the experimental results. Moreover, a numerical analysis approach based on the FE technique was proposed for the prediction of the shear strength. The results show that corrosion of the reinforcements could reduce the shear strength of the RC beams. The corrosion of stirrups can be numerically simulated by the reduction of the cross section. The formulae in the literature are conservative and the predictions are very dispersed, while the predictions by the proposed formula agree very well with the experiment results.

scholarly journals TACHYON DYNAMICS OF THE BLACK DISC LIMIT IN THE HARD SMALL x PROCESSES IN QCD

2006 ◽  
Vol 21 (07) ◽  
pp. 549-558 ◽  
Author(s):  
B. BLOK ◽  
L. FRANKFURT
Keyword(s):  
Cross Section ◽  
Impact Parameter ◽  
High Energy ◽  
Black Disk ◽  
Black Disc ◽  
Energy Behavior ◽  
Small X ◽  
The Cross ◽  
The Impact ◽  
Black Disc Limit

We investigate the effective field theory (EFT) which gives the approximate description of the scattering of two hard small dipoles in the small x processes in QCD near the black disc limit (BDL). We argue that the perturbative QCD approaches predict the existence of tachyon and visualize it in the approximation where α′P=0. We demonstrate that the high energy behavior of the cross-section depends strongly on the diffusion law in the impact parameter plane. On the other hand, almost threshold behavior of the cross section of the hard processes and multiplicities, i.e. fast increase of cross sections (color inflation), melting of ladders into color network and softening of the longitudinal distributions of hadrons are qualitatively insensitive to the value of diffusion in the impact parameter space. We evaluate α′P near the black disk limit and find significant α′P as the consequence of the probability conservation.

The impact of culture on millennials' attitudes towards luxury brands: evidence from Tokyo and Shanghai

2022 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Cheng Lu ◽  
Zhencong Sang ◽  
Kun Song ◽  
Kazuo Kikuchi ◽  
Ippei Machida
Keyword(s):  
Social Identity ◽  
Peer Influence ◽  
Positive Impact ◽  
Cross Cultural ◽  
Mediating Effect ◽  
Luxury Brands ◽  
Content Type ◽  
The Social ◽  
The Cross ◽  
The Impact

PurposeBased on the theory of social identity mechanism, this study aimed to investigate the associations with millennial consumers' need for uniqueness (NFU), susceptibility to peer influence (SPI) and attitudes towards luxury brands (ALB) under the cross-cultural context. The mediating effect of fashion innovativeness (FI) and the moderating effect of culture were examined.Design/methodology/approachThe data for this study were collected through a survey from 217 millennials in Shanghai and 268 millennials in Tokyo. Moderation analysis and mediation analysis using Hayes PROCESS macro were applied to test proposed hypotheses.FindingsResults show that NFU and SPI have a significantly positive effect on millennials' ALB, and fashion innovativeness plays a mediating role in this process. Furthermore, the positive impact of NFU on millennials' ALB for relatively individualistic cities (Shanghai) is stronger than for relatively collectivist cities (Tokyo). The positive impact of susceptibility to informative influence (SII) on millennials' ALB for Tokyo is stronger than for Shanghai.Practical implicationsThe research results suggest how different cultures can support marketers in effectively carrying out their business strategy.Originality/valueUnder the cross-cultural background, the social identity mechanism behind the attitudes of millennials towards luxury brands has been widely recognised. However, little is known about how culture could moderate the social identity mechanism behind millennials' ALB. By analysing these mechanisms, this study compares the cultures of Shanghai and Tokyo and expands the previous research achievements.

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