scholarly journals Do cognitive tasks during gait increase the risk of accidents with pedestrians? A study based on electromyographic parameters

2017 ◽  
Vol 30 (1) ◽  
pp. 125-132
Author(s):  
Camilla Zamfolini Hallal ◽  
Marcelo Tavella Navega ◽  
José Adolfo Menezes Garcia Silva ◽  
Deborah Hebling Spinoso ◽  
Mary Hellen Morcelli ◽  
...  
Keyword(s):  
Muscle Activation ◽  
Cognitive Tasks ◽  
Cognitive Resources ◽  
Adult Women ◽  
Safe Driving ◽  
Younger Women ◽  
Significant Difference ◽  
Young Subjects ◽  
Serious Injuries ◽  
Complex Planning

Abstract Introduction Accidents involving pedestrians are responsible for many cases of serious injuries and deaths. Crossing streets safely requires complex planning and cognitive demand because it is necessary to perform more than one task at a time. Objective The aim of this study was to identify electromyographic changes during gait in young subjects who performed the cognitive tasks concurrently. Methods The study included 17 younger women aged between 18 and 25 years. Data collection was performed on a treadmill. The volunteers were instructed to walk in four different conditions: normal gait (NG), gait with dual easy task (DET), gait with dual hard task (DHT) and gait with dual mixed task (DMT). Results Significant differences were found between the MN condition to the other conditions for all muscles and, during the NG, smaller values of muscle activation were found. Muscle co-contraction between muscles VM / BF showed a significant difference between the conditions of NG and DMT (p = 0.04) and, during the NG, smaller values of co-contraction were observed. Conclusion The data of this study permits to conclude that the competition between motor and cognitive resources significantly affects the levels of muscle activation and co-contraction during gait in young adult women. Thus, we conclude that the performance of dual cognitive tasks while driving can be considered a risk factor for safe driving.

scholarly journals POS1288 TUBERCULOUS SPONDYLODISCITIS IN ELDERLY: EPIDEMIOLOGY, CLINICAL, FEATURES, TREATMENT AND OUTCOMES

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 926.1-926
Author(s):  
M. Mrabet ◽  
S. Boussaid ◽  
S. Jemmali ◽  
H. Sahli ◽  
H. Ajlani ◽  
...  
Keyword(s):  
Clinical Features ◽  
The Elderly ◽  
Lumbar Pain ◽  
Elderly Subjects ◽  
Normocytic Anemia ◽  
Imaging Features ◽  
X Rays ◽  
Significant Difference ◽  
Young Subjects ◽  
Tuberculous Spondylodiscitis

Background:Tuberculosis is still endemic all over the world. The incidence of tuberculous spondylodiscitis (TS) is steadily increasing. Clinical features and outcomes of this affection are various and depending on various parameters, including age.Objectives:Our objective was to explore the differences in presentation and the results of further investigations and the prognosis of TS between young and elderly subjects.Methods:We conduct a retrospective and descriptive study in a single rheumatology department. Data were collected from files of patients hospitalized in the past 20 years (2000-2020) who have been diagnosed with TS. We carried out a comparative study concerning the clinical biological, imaging features and outcomes between young subjects and subjects aged over 65 years.Results:Fifty-two cases of TS were collected (37F/15M). The mean age of the population was 55.21 years ± 17.79 [19-91]. Thirty-three patients (69.2%) were classified as young versus 16 elderly patients (30.8%), with female predominance in both groups (69.4% and 75% respectively, p = 0.57). Young subjects was more frequently vaccinated (88.9%) by Bacillus Calmette–Guérin (BCG) (p < 0.001). A delayed diagnosis was noted in both groups (p = 0.24). Lumbar spine involvement was the most common (57.7%). In the two age ranges, the onset of the disease was progressive (p = 0.22), characterized by segmental spine stiffness (p = 0.57) and lumbar pain with general signs (p = 0.27), such as: impaired general condition, fever, night sweats and weight loss. Biological inflammatory syndrome and normochrome normocytic anemia were encountered in both cases (p = 0.08 and p = 0.2, respectively). Standard X-rays and Computed tomography were more performed in young subjects (94.4% and 69.4%, respectively; p < 0.001), unlike magnetic resonance imaging which was more common in elderly subjects but with no statistically significant difference (p = 0.22). Disc pinch, erosion of vertebral plateaus and vertebral collapse were the major signs (82.7%, 65.4% and 67.3%, respectively). Clinical, biological and imaging arguments contributed to positive diagnosis in both groups (p = 0.24). Common medical treatment was anti-tuberculosis: Isoniazid (H), Rifampicin (R), Pyrazinamide (Z), Ethambutol (E) and physical treatment such as immobilization witch was more common in the eldery (56.3%, p = 0.16). The evolution of the disease was characterized by a clear improvement of young subjects during the second week of treatment (p < 0.001). A more frequent clinical improvement in older subjects was during the fourth week but with no statistically significant difference (p = 0.13). The occurrence of immediate complications was more frequent in the elderly (p = 0.23) with a predominance for drug complications (56.3%) such as: hepatic cytolysis (12.5%), hyperuricemia (18.8%) and major intolerance to anti-tuberculosis (18.8%).Conclusion:TS is a frequent condition that needs to be treated rapidly. the clinical presentation of TS in the elderly is less noisy which leads to more frequent complications and mortality.Disclosure of Interests:None declared

scholarly journals Utilization of preimplantation genetic testing in the USA

2021 ◽  
Author(s):  
Kaitlyn Roche ◽  
Catherine Racowsky ◽  
Joyce Harper
Keyword(s):  
Genetic Testing ◽  
Older Women ◽  
State Level ◽  
Oocyte Retrieval ◽  
Preimplantation Genetic Testing ◽  
Annual Increase ◽  
Younger Women ◽  
Live Birth Rates ◽  
Significant Difference ◽  
The Usa

Abstract Purpose To evaluate the use of preimplantation genetic testing (PGT) and live birth rates (LBR) in the USA from 2014 to 2017 and to understand how PGT is being used at a clinic and state level. Methods This study accessed SART data for 2014 to 2017 to determine LBR and the CDC for years 2016 and 2017 to identify PGT usage. Primary cycles included only the first embryo transfer within 1 year of an oocyte retrieval; subsequent cycles included transfers occurring after the first transfer or beyond 1 year of oocyte retrieval. Results In the SART data, the number of primary PGT cycles showed a significant monotonic annual increase from 18,805 in 2014 to 54,442 in 2017 (P = 0.042) and subsequent PGT cycles in these years increased from 2946 to 14,361 (P = 0.01). There was a significant difference in primary PGT cycle use by age, where younger women had a greater percentage of PGT treatment cycles than older women. In both PGT and non-PGT cycles, the LBR per oocyte retrieval decreased significantly from 2014 to 2017 (P<0001) and younger women had a significantly higher LBR per oocyte retrieval compared to older women (P < 0.001). The CDC data revealed that in 2016, just 53 (11.4%) clinics used PGT for more than 50% of their cycles, which increased to 99 (21.4%) clinics in 2017 (P< 0.001). Conclusions A growing number of US clinics are offering PGT to their patients. These findings support re-evaluation of the application for PGT.

scholarly journals Investigation of different stimulation patterns with doublet pulses to reduce muscle fatigue

2019 ◽  
Vol 6 ◽  
pp. 205566831982580 ◽  
Author(s):  
Ruslinda Ruslee ◽  
Jennifer Miller ◽  
Henrik Gollee
Keyword(s):  
Electrical Stimulation ◽  
Muscle Fatigue ◽  
Functional Electrical Stimulation ◽  
Muscle Activation ◽  
Motor Units ◽  
Pulse Interval ◽  
Time Interval ◽  
Fatigue Index ◽  
Significant Difference ◽  
Cord Injury

Introduction: Functional electrical stimulation is a common technique used in the rehabilitation of individuals with a spinal cord injury to produce functional movement of paralysed muscles. However, it is often associated with rapid muscle fatigue which limits its applications. Methods: The objective of this study is to investigate the effects on the onset of fatigue of different multi-electrode patterns of stimulation via multiple pairs of electrodes using doublet pulses: Synchronous stimulation is compared to asynchronous stimulation patterns which are activated sequentially (AsynS) or randomly (AsynR), mimicking voluntary muscle activation by targeting different motor units. We investigated these three different approaches by applying stimulation to the gastrocnemius muscle repeatedly for 10 min (300 ms stimulation followed by 700 ms of no-stimulation) with 40 Hz effective frequency for all protocols and doublet pulses with an inter-pulse-interval of 6 ms. Eleven able-bodied volunteers (28 ± 3 years old) participated in this study. Ultrasound videos were recorded during stimulation to allow evaluation of changes in muscle morphology. The main fatigue indicators we focused on were the normalised fatigue index, fatigue time interval and pre-post twitch–tetanus ratio. Results: The results demonstrate that asynchronous stimulation with doublet pulses gives a higher normalised fatigue index (0.80 ± 0.08 and 0.87 ± 0.08) for AsynS and AsynR, respectively, than synchronous stimulation (0.62 ± 0.06). Furthermore, a longer fatigue time interval for AsynS (302.2 ± 230.9 s) and AsynR (384.4 ± 279.0 s) compared to synchronous stimulation (68.0 ± 30.5 s) indicates that fatigue occurs later during asynchronous stimulation; however, this was only found to be statistically significant for one of two methods used to calculate the group mean. Although no significant difference was found in pre-post twitch–tetanus ratio, there was a trend towards these effects. Conclusion: In this study, we proposed an asynchronous stimulation pattern for the application of functional electrical stimulation and investigated its suitability for reducing muscle fatigue compared to previous methods. The results show that asynchronous multi-electrode stimulation patterns with doublet pulses may improve fatigue resistance in functional electrical stimulation applications in some conditions.

Decreased Neutrophil Cyclic AMP Response to Isoprenaline Stimulation in the Elderly

1983 ◽  
Vol 65 (2) ◽  
pp. 155-157 ◽  
Author(s):  
T. G. Cotter ◽  
K. O'Malley
Keyword(s):  
Monoclonal Antibodies ◽  
Cyclic Amp ◽  
The Elderly ◽  
Population Heterogeneity ◽  
Elderly Subjects ◽  
Age Related ◽  
Significant Difference ◽  
Young Subjects ◽  
Drug Free

1. Neutrophils from drug-free elderly subjects produced approximately 50% less cyclic AMP in response to isoprenaline than did neutrophils from young subjects. A significant difference in basal cyclic AMP levels was also evident (elderly 2.8 ± 0.37; young 4.9 ± 0.36 pmol of cAMP/107 cells; P < 0.05). 2. With a range of anti-neutrophil monoclonal antibodies no evidence of age-related neutrophil population heterogeneity was found. 3. These findings indicate that the age-related decline in β-adrenoceptor responsiveness is not due to changes in the neutrophil population. 4. The present results support the hypothesis that there is a generalized decline in β-adrenoceptor-mediated responsiveness in the elderly.

scholarly journals Function, strength, and muscle activation of the shoulder complex in Crossfit practitioners with and without pain: a cross-sectional observational study

2022 ◽  
Vol 17 (1) ◽  
Author(s):  
Elisa Raulino Silva ◽  
Nicola Maffulli ◽  
Filippo Migliorini ◽  
Gilmar Moraes Santos ◽  
Fábio Sprada de Menezes ◽  
...  
Keyword(s):  
Shoulder Pain ◽  
Surface Electromyography ◽  
Shoulder Joint ◽  
Muscle Activation ◽  
National Registry ◽  
Kinetic Chain ◽  
Balance Test ◽  
Cross Sectional ◽  
Significant Difference ◽  
Lower Trapezius

Abstract Background The shoulder joint is the most commonly injured joint in CrossFit practitioners, because of the high intensity and loads associated with this sport. Despite the large number of clinical cases, there is a shortage of studies that investigate influence of biomechanical aspects of upper limbs' injuries on CrossFit practitioners. This study hypothesized that there would be a difference in function, strength, and muscle activation between Crossfit practitioners with and without shoulder pain. Methods We divided 79 Crossfit practitioners into two groups according to whether they reported pain (n = 29) or no pain (n = 50) in the shoulder during Crossfit training. Muscle function, strength, and activation were assessed using the Disability Arm, Shoulder and Hand function questionnaire, Upper Quarter Y Balance Test and Closed Kinetic Chain Upper Extremity Stability Test shoulder tests, isometric muscle strength assessment by manual dynamometry and muscle activation by surface electromyography and pain report. Results The function based on questionnaire was associated with pain (p = 0.004). We observed a statistically significant difference between the two groups only in the surface electromyography activity of the lower trapezius, and in the variables of shoulder pain and function (p = 0.038). Conclusion Crossfit practitioners with shoulder pain occurring during training showed good function and stability of the shoulder joint, but there was a reduction in the activation of stabilizing muscles, especially the lower trapezius. Trial registration Registro Brasileiro de Ensaios Clinico (Brasilian National Registry) with the ID: RBR-2gycyv.

scholarly journals Xyloglucan, Hibiscus and Propolis in the Management of Uncomplicated Lower Urinary Tract Infections: A Systematic Review and Meta-Analysis

Antibiotics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 14
Author(s):  
Tommaso Cai ◽  
Umberto Anceschi ◽  
Irene Tamanini ◽  
Serena Migno ◽  
Michele Rizzo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Medical Device ◽  
Meta Analysis ◽  
Clinical Effectiveness ◽  
Adult Women ◽  
End Of Treatment ◽  
Significant Difference ◽  
Clinically Significant ◽  
Tract Infections ◽  
Uncomplicated Cystitis

Background: In the era of antibiotic resistance, an antibiotic-sparing approach presents an interesting alternative treatment of uncomplicated cystitis in women. Our aim is to perform a systematic review and meta-analysis to compare the effectiveness and safety profile of a medical device containing xyloglucan, hibiscus and propolis (XHP) in women with uncomplicated cystitis. Methods: Relevant databases were searched using methods recommended by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The primary endpoint was clinical or microbiological success, defined as the complete (cure) and/or non-complete (improvement) resolution of symptoms at the end of treatment, or microbiological resolutions. Results: After screening 21 articles, three studies were included, recruiting a total of 178 patients. All three studies used placebo as comparator. A statistically significant difference was found in terms of clinical or microbiological resolution between the medical device and the comparator (3 RCTs, 178 patients, OR: 0.13; 95% CI: 0.05–0.33; p < 0.0001). No clinically significant adverse effects have been reported. Conclusion: A medical device containing xyloglucan, hibiscus and propolis is superior to comparator regimens in terms of clinical effectiveness in adult women with microbiologically confirmed or clinical suspicion of uncomplicated cystitis and is associated with a high patient compliance.

scholarly journals The Effect of Sound and Vibration on Postural Balance in Healthy Young Adults

2018 ◽  
Vol 16 (12) ◽  
pp. 975-983
Author(s):  
Sunee BOVONSUNTHONCHAI ◽  
Pichaya HENGSOMBOON ◽  
Sitapa TANGLUANG ◽  
Pran ANUSRI ◽  
Pavitta CHOTIKUL ◽  
...  
Keyword(s):  
Young Adults ◽  
Interaction Effect ◽  
Postural Balance ◽  
Center Of Pressure ◽  
Force Plate ◽  
Repeated Measure ◽  
Significant Difference ◽  
Main Effect ◽  
Young Subjects ◽  
The One

Postural balance is influenced by alteration of somatosensory inputs. Sound and vibratory senses, one of several human senses may assist the postural control in a specific impaired situation. The aim of this pilot study was to quantify the effect of sound and vibration on postural balance in healthy young adults. Ten healthy young subjects volunteered to participate in the study. The average age, weight, height, and body mass index were 21.88 ± 0.42 years, 56.21 ± 9.80 kg, 159.75 ± 5.20 cm, and 21.99 ± 3.52 kg/m2. They were assessed for standing postural balance on a force plate over 6 conditions of sound and vibration applications under vision was excluded by using a blindfold. Postural balance variables consisted of planar deviation of Center of Pressure (CoP) and the maximum ranges of CoP in the medio-lateral (ML) and antero-posterior (AP) directions. Two-way ANOVA was used to find the effect and interaction effect of sound and vibration on the postural balance variables. Further analyses of the variables were performed on a basis of each factor. Between sound conditions (no sound and open sound), the variables were analyzed by the paired t-test. In addition, the effect of vibration (no vibration, vibration on quadriceps, and vibration on gastrocnemius) on the variables were analyzed by the one-way repeated measure ANOVA. Results demonstrated no interaction effect and main effect of sound and vibration on the postural balance variables (p > 0.05). In addtion, no significant difference of the postural balance variables between sound conditions (p > 0.05) as well as among vibration conditions (p > 0.05). In conclusion, sound and vibration did not effect to the postural balance during standing in healty young adults.

Validation and comparison of trunk muscle activities in male participants during exercise using an innovative device and abdominal bracing maneuvers

2021 ◽  
pp. 1-8
Author(s):  
Yuki Kurokawa ◽  
Satoshi Kato ◽  
Satoru Demura ◽  
Kazuya Shinmura ◽  
Noriaki Yokogawa ◽  
...  
Keyword(s):  
Muscle Activity ◽  
Muscle Activation ◽  
Voluntary Contraction ◽  
Trunk Muscle ◽  
Erector Spinae ◽  
Trunk Muscles ◽  
Activity Levels ◽  
Significant Difference ◽  
External Oblique ◽  
Internal Oblique

BACKGROUND: Abdominal bracing is effective in strengthening the trunk muscles; however, assessing performance can be challenging. We created a device for performing abdominal trunk muscle exercises. The effectiveness of this device has not yet been evaluated or compared OBJECTIVE: We aimed to quantify muscle activity levels during exercise using our innovative device and to compare them with muscle activation during abdominal bracing maneuvers. METHODS: This study included 10 men who performed abdominal bracing exercises and exercises using our device. We measured surface electromyogram (EMG) activities of the rectus abdominis (RA), external oblique, internal oblique (IO), and erector spinae (ES) muscles in each of the exercises. The EMG data were normalized to those recorded during maximal voluntary contraction (%EMGmax). RESULTS: During the bracing exercise, the %EMGmax of IO was significantly higher than that of RA and ES (p< 0.05), whereas during the exercises using the device, the %EMGmax of IO was significantly higher than that of ES (p< 0.05). No significant difference was observed in the %EMGmax of any muscle between bracing exercises and the exercises using the device (p= 0.13–0.95). CONCLUSIONS: The use of our innovative device results in comparable activation to that observed during abdominal bracing.

The Effects of Taping on Muscle Activity and Throwing Velocity in Fatigued Baseball Players

2021 ◽  
Vol 3 (1) ◽  
pp. 18-29
Author(s):  
Kara-Lyn R. Harrison ◽  
Paolo Sanzo ◽  
Carlos Zerpa ◽  
Taryn Klarner
Keyword(s):  
Pilot Study ◽  
Muscle Activity ◽  
Muscle Activation ◽  
Performance Enhancement ◽  
Maximum Velocity ◽  
Baseball Players ◽  
Kinesio Tape ◽  
Significant Difference ◽  
Post Test ◽  
And Performance

Due to the repetitive high forces and torques placed on an individual during a baseball pitch, shoulder pain is present in 46-57% of pitchers. Therapeutic taping has been proposed to have beneficial qualities in injury prevention, rehabilitation, and performance enhancement via muscular facilitation. Therefore, the purpose of this pilot study was to investigate the effect of taping on the velocity of an overhead baseball throw and muscle activation patterning of the supraspinatus, infraspinatus, and pectoralis major muscles in baseball players after muscle fatigue was induced. Participants were asked to complete three pre-test maximum velocity overhead throws, a fatiguing protocol, followed by three post-test maximum velocity pitches. There was no statistically significant difference in throwing velocity or muscle activity with the application of the different taping conditions in the three phases of an overhead baseball throw. These finding suggest Kinesio Tape® does not change muscle activation or velocity of overhead baseball throws when compared to a no tape condition.

Effect of Muscle Activation on the Gravity Stress View in Unstable Weber B Ankle Fractures

2020 ◽  
Vol 41 (11) ◽  
pp. 1342-1346
Author(s):  
Kimberly K. Broughton ◽  
Caroline Williams ◽  
Christopher P. Miller ◽  
Kristen Stupay ◽  
John Y. Kwon
Keyword(s):  
Muscle Activation ◽  
False Negative ◽  
Ankle Fractures ◽  
Published Data ◽  
Neutral Position ◽  
Distal Fibula ◽  
Level Of Evidence ◽  
Negative Results ◽  
False Negative Results ◽  
Significant Difference

Background: In the setting of apparently isolated distal fibula fractures, the gravity stress view (GSV) is a validated method to determine mortise stability. There is currently no published data evaluating whether dynamic muscle activation can reduce an unstable mortise. If patients with instability can overcome gravity, resultant images could yield false-negative results. The goal of this investigation was to determine if patient effort can influence medial clear space (MCS) measurements in proven unstable bimalleolar-equivalent ankle fractures. Methods: Patients presenting with Weber B fibula fractures were assessed for mortise stability using the GSV. If the GSV demonstrated instability based on MCS widening >4 mm, 3 additional views were performed: GSV with an assistant maintaining the ankle in a neutral position; GSV with the patient actively dorsiflexing to neutral; and GSV with the patient actively dorsiflexing and supinating the foot. Twenty-four consecutive patients met inclusion criteria, with a mean age of 48.7 (range, 22-85) years. Fifteen patients (62.5%) were female and 9 (37.5%) were male. The laterality was evenly divided. Results: The mean MCS was 5.8 ± 2.0 6.0 ± 2.6, and 6.2 ± 2.7 mm for the manual assist, active dorsiflexion, and active supination radiograph measurement groups, respectively ( P = .434). Only 5 of 24 subjects had any measurable decrease in their MCS with active supination, with a maximum change of 1.2 mm. The remainder of the patients had an increase in MCS ranging from 0.1 to 4.0 mm. Conclusion: There was no significant difference between measurement states indicating that muscle activation is unlikely to yield a false-negative result on GSV. Mortise instability, secondary to deep deltoid injury in the presence of gravity stress, is unlikely to be actively overcome by dynamic stabilizers, supporting the validity and specificity of the GSV. Level of Evidence: Level III, prospective study.

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