scholarly journals Handgrip strength and its relation to isokinetic dynamometry in COPD

2020 ◽  
Vol 33 ◽  
Author(s):  
Marisandra Flesch Nunes ◽  
Bruno Barcellos Hervé ◽  
Janice Luísa Lukrafka ◽  
Mariane Borba Monteiro
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Strong Correlation ◽  
Handgrip Strength ◽  
The Body ◽  
Isokinetic Dynamometer ◽  
Isokinetic Dynamometry ◽  
Peripheral Muscle ◽  
Significant Difference

Abstract Introduction: Muscle dysfunction is one of the major changes found in chronic obstructive pulmonary disease (COPD) and associated with loss of functionality, morbidity and mortality. Objective: correlate two strength assessment methods: manual dynamometry for handgrip strength and isokinetic dynamometry for quadriceps strength in patients with COPD, and assess the body mass index, airflow obstruction, dyspnea, and exercise capacity (BODE), quality of life and muscle strength. Method: twenty-five patients with moderate to very severe COPD were evaluated by pulmonary function parameters, anthropometric variables, functional capacity, via the six-minute walk test, dyspnea, applying the modified Medical Research Council (mMRC) scale, BODE, quality of life, using the Saint George's Respiratory Questionnaire (SGRQ), handgrip strength with manual dynamometer and quadriceps force using an isokinetic dynamometer. Muscle strength was assessed with a manual portable dynamometer and isokinetic dynamometer. For statistical analysis, ANOVA with Bonferroni’s post-test, the chi-squared test and Pearson's correlation coefficient were used. Results: There was a strong correlation between the strength measurements and the two instruments (torque and quadriceps extension power with right handgrip strength: r = 0.74; p <0.001). The patients classified as very severe exhibited worse performance in the strength tests when compared to the moderate group, albeit with no statistically significant difference. Conclusion: In muscle strength measurements, a strong correlation was detected between the isokinetic dynamometer for quadriceps and the manual dynamometer for handgrip strength. These findings indicate that, in clinical practice, the manual dynamometer for handgrip strength could be used to assess peripheral muscle strength in patients with COPD.

scholarly journals Influence of Hemoglobin Level on Muscle and Physical Functions, Activities of Daily Living, and Quality of Life in Patients With Hematological Malignancies

2019 ◽  
Vol 18 ◽  
pp. 153473541984219 ◽  
Author(s):  
Takuya Fukushima ◽  
Jiro Nakano ◽  
Shun Ishii ◽  
Ayumi Natsuzako ◽  
Haruna Kawachi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Activities Of Daily Living ◽  
Physical Function ◽  
Daily Living ◽  
Hematological Malignancies ◽  
Physical Symptoms ◽  
Significant Difference ◽  
Physical Functions

Purpose. Patients with hematological malignancies often present with reduced muscle and physical functions, which are caused by the disease or related treatment. Moreover, patients with hematological malignancies rapidly develop low hemoglobin levels, and this may affect muscle and physical functions. This study aimed to identify the influence of hemoglobin levels on muscle and physical functions in patients with hematological malignancies. Methods. Using a cross-sectional study design, this study included 60 patients with hematological malignancies (mean age = 68.0 ± 10.2 years, women 56.7%) who were hospitalized for chemotherapy- and radiotherapy-related side effects and underwent examination for skeletal muscle mass (SMM), muscle strength, physical function, activities of daily living (ADLs), psychological status, and quality-of-life (QOL), including physical symptoms. Participants were divided into 3 groups according to tertiles of hemoglobin levels: low (n = 19), middle (n = 20), and high (n = 21). Evaluation items were compared among the 3 groups. Results. There was no significant difference among the 3 groups in terms of SMM. The low hemoglobin group showed significantly higher values of fatigue and dyspnea and lower values of muscle strength, ADLs, and QOL than the high hemoglobin group. Conclusions. Hemoglobin levels did not affect SMM; however, muscle weakness, decrease in physical function, physical symptoms such as fatigue and dyspnea, and decline in ADLs and QOL were observed in patients with low hemoglobin levels.

scholarly journals Quality of Life in Uveal Melanoma Patients in Ireland: A Single-Centre Survey

2019 ◽  
Vol 6 (2) ◽  
pp. 99-106
Author(s):  
Olya Scannell ◽  
Valerie O’Neill ◽  
Mary Dunne ◽  
Caroline Baily ◽  
Amira Salih ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Uveal Melanoma ◽  
Psychosocial Support ◽  
Well Being ◽  
Disease Recurrence ◽  
The Body ◽  
Treatment Groups ◽  
Significant Difference ◽  
Melanoma Patients

Background: Uveal melanoma and its treatment can influence the physical and psychological well-being of patients in a way that differs from other cancers. Factors influencing quality of life (QOL) include visual impairment, changes in appearance, day-to-day functioning, ocular discomfort, and worry regarding disease recurrence. Objective: We aimed to study both general and disease-specific QOL in uveal melanoma patients in Ireland and compare QOL between a plaque radiotherapy group and an enucleation treatment group. This information was sought to enhance our understanding of QOL issues for uveal melanoma patients, in the context of improving care and providing appropriate psychosocial support. Method: The European Organisation for Research and Treatment of Cancer (EORTC) QOL questionnaires QLQ-C30 and QLQ-OPT30 were completed by patients with uveal melanoma treated by enucleation or brachytherapy. Results: 138 of 206 patients completed the questionnaires. There was no significant difference in QOL scores between treatment groups. Thirty-two percent of patients reported concerns about tumour recurrence elsewhere in the body. The brachytherapy group had a significantly higher “role functioning” score (p = 0.030). Enucleation patients were more likely to have problems with appearance (p < 0.0005). Younger patients (12–54 years of age) were more likely to report headaches (p < 0.0005) and problems with reading (p = 0.042), and they had a lower cognitive functioning score (p = 0.003) than those aged ≥55 years. Conclusions: There was no significant difference in reported QOL between treatment groups. Our data identified a number of vulnerable patient subgroups. By anticipating which patients are more likely to suffer in terms of certain aspects of their QOL, we are better able to provide appropriate and timely psychosocial support.

scholarly journals Pacemaker implications in the functional capacity and quality of life of cardiopathic patients

2019 ◽  
Vol 32 ◽  
Author(s):  
Tainá Samile Pesente ◽  
Tiago Luan Labres de Freitas ◽  
Jaqueline Piccoli Korb ◽  
Juliana Nunes Ferreira ◽  
Alexandre Simões Dias ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Muscle Strength ◽  
Cardiorespiratory Fitness ◽  
Respiratory Muscle ◽  
Respiratory Muscle Strength ◽  
Large Hospital ◽  
The North ◽  
Peripheral Muscle

Abstract Introduction: Cardiovascular diseases are among the main causes of death, and in recent years there has been an increase in pacemaker implants (PM), which is intended not only to increase survival, but also to improve quality of life. Objective: To evaluate the quality of life, cardiorespiratory fitness and level of physical activity of patients before and after permanent PM implant in a large hospital in the north of the state of Rio Grande do Sul. Method: The study comprised 19 patients submitted to PM surgery who had their electronic health record and quality of life (AQUAREL) evaluated as well as their cardiorespiratory fitness and the limit of daily physical activity (VSAQ), peripheral muscle strength (PMS), respiratory muscle strength (manovacuometry), their degree of dyspnea (modified PMS) and the hemodynamic parameters, all of which were assessed in the preoperative period and after 30 days. Results: A mean age of 71.79 years was observed and in 63.1% of the cases Total Atrioventricular Block was the pathology, while 89.5% of the participants presented systemic arterial hypertension and 31.6% also presented Diabetes Melittus. Statistically significant improvement was observed in all the values under evaluation, namely: dyspnea (p = 0.0001), peripheral muscle strength (p = 0.0001) and respiratory muscle strength (PIMAX p = 0.0001 and PEMAX p = 0.0001), Quality of Life (p = 0.0001) and Cardiorespiratory Fitness and level of physical activity p=0.0001). Conclusion: Improvement was verified in all parameters analyzed, thus suggesting that the PM positively influences the quality of life and the functionality of the patients.

scholarly journals Quality of Life, Behavioural Activation and Inhibition and Perceived Social Competence among Drug Addicts

2021 ◽  
Vol 4 (1) ◽  
pp. 131-142
Keyword(s):  
Quality Of Life ◽  
Social Competence ◽  
Drug Addiction ◽  
Family System ◽  
Nuclear Family ◽  
Life Quality ◽  
The Body ◽  
Drug Addicts ◽  
Significant Difference

The purpose of this article was to shower light on the quality of life that mostly we expect. Life quality is determined by two aspects i.e., physiological and psychological aspects. While if a person is addicted by the drugs, then the both aspects of his/ her life is deteriorated to the extreme. Due to drug addiction, the negative psychological effects which arises are anxiety, stress, depression, and familial relationships while the negative physiological effects that arise from the drug addiction are weakness, headache, dizziness, and pain in the body, etc. The main objective was to evaluate the quality of life of Diamorphine addicts, behavioral stimulation and inhibition, perceived social competence, and the relationship between these variables; and check differences between drug addicts on these variables based on their belongingness to joint and nuclear family systems. To achieve the objectives, 10 Diamorphine addicts were taken from Azm Drug Rehabilitation center, Sargodha, through purposive sampling. A total number of 10 participants responded to the 26-items quality of life survey (WHO-QOL-BREF), 24-items BAS/BIS (BIS/BAS scale) questionnaire, and 5-items perceived social competence questionnaire (Perceived Social Competence Scale II). Results were analyzed via SPSS version 20. The results showed that all three variables in the study were not associated with each other. Quality of life and social competence correlated -.25 (p = n.s); quality of life and BAS/BIS had .30 (p = n.s); while social competence and BAS/BIS had -.16 (p = n.s). It may be due to the cultural settings of Pakistan. In drug addicts, BAS has high activity, and BIS has low activity. And there is no significant difference in these variables among addicts of the nuclear and joint family system.

scholarly journals Association between muscle strength and health-related quality of life in a Chinese rural elderly population: a cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. e026560 ◽  
Author(s):  
Shanshan Yang ◽  
Tianzhi Li ◽  
Hongbing Yang ◽  
Jianhua Wang ◽  
Miao Liu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Elderly Population ◽  
Handgrip Strength ◽  
Cross Sectional Study ◽  
Rural Elderly ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

ObjectiveTo investigate the relationship between upper and lower limb muscle strength and the health-related quality of life (HRQoL) of a Chinese rural, elderly population.DesignA population-based, cross-sectional study.SettingMiyun, Beijing, China.ParticipantsThe participants of this study were 2083 (834 men and 1249 women) older adults from a rural area, (average age of ≥60 years), living in Miyun county, located on the outskirts of Beijing. Data were collected between May and October 2014. Handgrip strength and timed up and go tests (TUGT) were conducted to measure the muscle strength of their upper and lower limbs, respectively. The Euro Quality of Life (Euroqol) (EQ-5D)-Visual Analogue Scale was used to evaluate participants’ HRQoL.ResultsA significant association between handgrip strength and the EQ-5D index (β=0.015 per SD, 95% CI: 0.008 to 0.023, p<0.001) was discovered, following adjustments. The association between handgrip strength and the EQ-5D index in the ≥80 years group was found to be stronger than that of the 60–79 years group, following adjustment (β per SD: 0.013 vs 0.035). Similar results were observed when comparing the non-chronic disease group, in terms of TUGT time, against those with chronic diseases.ConclusionsThere was a significant relationship between muscle strength (measured via handgrip strength and TUGT time) and HRQoL (measured via EQ-5D index and VAS score) in the Chinese rural elderly population. Furthermore, this relationship was stronger in the older population (aged ≥80 years), and in those participants diagnosed with chronic diseases.

scholarly journals P0944UREMIC SARCOPENIA IN THE ELDER: PRELIMINARY RESULTS OF A PRECISION MEDICINE APPROACH IN A COHORT OF UREMIC PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Rocco Baccaro ◽  
Wanda Lattanzi ◽  
Francesca Maria D'Ascenzo ◽  
Patrizia Silvestri ◽  
Giovanni Gambaro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Diagnostic Criteria ◽  
Muscle Mass ◽  
Gait Speed ◽  
Daily Activity ◽  
Handgrip Strength ◽  
Uremic Patients ◽  
Esrd Patients

Abstract Background and Aims Sarcopenia is defined as a chronic condition of “muscle failure”, characterized by reduced muscular strength, mass and performance. End-stage renal disease (ESRD) and sarcopenia have several complications in common including inflammation, low sexual hormones, reduced levels of Vitamin D, and low satellite cells proliferation rate. Sarcopenic and uremic patients have higher risk for fracture, cardiovascular events, cognitive impairment, low quality of life, hospitalization and death. The European Working Group on Sarcopenia in Older People (EWGSOP2) 2019 guidelines standardize the diagnostic criteria and recommend a systematic approach for sarcopenia assessment. The aim of our study is to evaluate the prevalence of sarcopenia in ESRD patients not yet on dialysis and to characterize their clinical, laboratory and behavioral features. Method This is a pilot cross-sectional study. ESRD patients expected to initiate replacement therapy (hemodialysis or peritoneal dialysis), age ≥60 years, free mobility and hemoglobin levels ≥9.5 g/dL were enrolled. Exclusion criteria were: use of steroids &gt;3 months during the previous year, previous renal replacement treatments. Enrolled patients were screened for sarcopenia following the three diagnostic criteria: muscle strength (through “handgrip strength” and “chair stand-up test”), muscle mass (with dual X-ray absorptiometry and bio-electrical impedance analysis), and muscle performance (with “4m gait speed test”). Clinical data were collected as well as anthropometric measures. Patients also underwent an abdominal ultrasound and a hematology, chemistry, urinary and inflammation laboratory panel. Finally, they filled questionnaires for sarcopenia identification (SARC-F), quality of life (SF-36), daily activity (ADL and iADL) and nutritional status. GFR was estimated according to CKD-EPI formula. Results We evaluated 9 patients (2 females and 7 males), mean age 72 ± 7 years, mean GFR 10.2±1.5 mL/min/1.73 m2 (range 7.3, 11.8). 7/9 reported hypertension history, 4/9 were diabetic. The prevalence of sarcopenia was 44% (4 patients) according EWGSOP2 criteria. Table 1 reports diagnostic exam results from our cohort. Taking individually EGWSOP2 criteria 4 patients showed low muscle strength, 5 reached the threshold for a low DXA muscle mass while 3 patients had a low gait speed performance, marker for sarcopenia severity. Compared with controls, sarcopenic patients (Table 2) showed a significantly lower handgrip strength (15.0±4.3 vs 23.0±6.7 Kg respectively, p-value 0.03), a lower but not significant appendicular lean mass (ALM) index normalized for squared height (European criteria) or for BMI (American criteria). Moreover, sarcopenic patients were more anemic (p 0.05), with a lower hematocrit (p 0.04). Finally, SF36 questionnaire describes sarcopenic patients as more jaded about physical activity, with impaired social activity and higher bodily pain. Conclusion Sarcopenia has a complex and diversified background, and ESRD represents an important risk factor. Sarcopenic patients with ESRD might need more carefulness on daily activity, anemia management, physical functioning and muscle recovery.

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