scholarly journals Odors as triggering and worsening factors for migraine in men

2011 ◽  
Vol 69 (2b) ◽  
pp. 324-327 ◽  
Author(s):  
A M Lima ◽  
G B Sapienza ◽  
V O Giraud ◽  
Y D Fragoso
Keyword(s):  
Patient Education ◽  
General Population ◽  
Environmental Factors ◽  
Cigarette Smoke ◽  
Special Focus ◽  
Related Factors ◽  
Triggering Factor ◽  
Males And Females ◽  
High Degree

OBJECTIVE: To assess the role of odors in triggering or worsening migraine in men. METHOD: Ninety-eight male migraineurs from the general population were assessed individually through questionnaires. Environmental factors relating to their migraine were reported, with special focus on the role of odors. RESULTS: Odors were the second most frequent triggering factor for migraine attacks (48%), behind stressful situations (59%). Likewise, odors were the second most frequent worsening factor (73%), just behind excessive light (74%). Thirty-three individuals (33.4%) stated that odors were both triggering and worsening factors for their migraine attacks. Perfume, cigarette smoke and cleaning products were the most frequent migraine-related odors reported by these male migraineurs. CONCLUSION: This was the first study to assess the role of odors in migraine exclusively in men. There was a high degree of odor-related migraine among these men, thus suggesting that patient education could alert such individuals to gender-related factors, since different triggering and worsening factors have been reported by males and females.

scholarly journals Zeaxanthin, a Molecule for Photoprotection in Many Different Environments

Molecules ◽  
2020 ◽  
Vol 25 (24) ◽  
pp. 5825
Author(s):  
Barbara Demmig-Adams ◽  
Jared J. Stewart ◽  
Marina López-Pozo ◽  
Stephanie K. Polutchko ◽  
William W. Adams
Keyword(s):  
Genetic Variation ◽  
Environmental Factors ◽  
Excitation Energy ◽  
Environmental Conditions ◽  
Xanthophyll Cycle ◽  
Field Studies ◽  
Photosynthetic Productivity ◽  
High Degree ◽  
Insight Into

Conversion of sunlight into photochemistry depends on photoprotective processes that allow safe use of sunlight over a broad range of environmental conditions. This review focuses on the ubiquity of photoprotection associated with a group of interconvertible leaf carotenoids, the xanthophyll cycle. We survey the striking plasticity of this process observed in nature with respect to (1) xanthophyll cycle pool size, (2) degree and speed of interconversion of its components, and (3) flexibility in the association between xanthophyll cycle conversion state and photoprotective dissipation of excess excitation energy. It is concluded that the components of this system can be independently tuned with a high degree of flexibility to produce a fit for different environments with various combinations of light, temperature, and other factors. In addition, the role of genetic variation is apparent from variation in the response of different species growing side-by-side in the same environment. These findings illustrate how field studies can generate insight into the adjustable levers that allow xanthophyll cycle-associated photoprotection to support plant photosynthetic productivity and survival in environments with unique combinations of environmental factors.

scholarly journals The Role of Probiotics in Chronic Rhinosinusitis Treatment: An Update of the Current Literature

Healthcare ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 1715
Author(s):  
Maria Rita Bianco ◽  
Massimo Ralli ◽  
Domenico Michele Modica ◽  
Marta Amata ◽  
Salvatore Poma ◽  
...  
Keyword(s):  
General Population ◽  
Environmental Factors ◽  
Medical Treatment ◽  
Chronic Rhinosinusitis ◽  
General Condition ◽  
The Body ◽  
Significant Health

Chronic rhinosinusitis (CRS) is a significant health problem. It affects 5–12% of the general population. The causes that underlie the onset of CRS are not yet well known. However, many factors may contribute to its onset, such as environmental factors and the host’s general condition. Medical treatment mainly uses local corticosteroids, nasal irrigation, and antibiotics. In recent years, a new therapeutic approach that employs the use of probiotics emerged. Probiotics have been extensively studied as a therapy for dysbiosis and inflammatory pathologies of various parts of the body. We aimed to examine the studies in vivo and in vitro and clinicals reports in the existing literature to update probiotics’ role in rhinosinusitis chronic medical treatment.

scholarly journals Environmental Factors and Endometriosis

2021 ◽  
Vol 18 (21) ◽  
pp. 11025
Author(s):  
Grzegorz Polak ◽  
Beata Banaszewska ◽  
Michał Filip ◽  
Michał Radwan ◽  
Artur Wdowiak
Keyword(s):  
Environmental Factors ◽  
Pelvic Pain ◽  
Common Disease ◽  
Related Factors

Endometriosis is a common disease, affecting up to 60–80% of women, with pelvic pain or/and infertility. Despite years of studies, its pathogenesis still remains enigmatic. Genetic, hormonal, environmental, and lifestyle-related factors may be involved in its pathogenesis. Thus, the design of the review was to discuss the possible role of environmental factors in the development of endometriosis. The results of individual studies greatly differ, making it very difficult to draw any definite conclusions. There is no reasonable consistency in the role of environmental factors in endometriosis etiopathogenesis.

Operator Experience and Accident Risk

1996 ◽  
Vol 40 (18) ◽  
pp. 947-951 ◽  
Author(s):  
T. J. Ayres ◽  
E. C. Lau ◽  
R. A. Schmidt ◽  
D. E. Young
Keyword(s):  
Environmental Factors ◽  
Product Safety ◽  
Motor Vehicles ◽  
Accident Risk ◽  
Major Category ◽  
Consumer Product Safety Commission ◽  
Related Factors ◽  
Operator Experience ◽  
The U.S

It has long been recognized that the risk of operating motor vehicles declines as operator experience increases, even when operator age is deconfounded. In this paper, causal analyses of accidents involving all-terrain vehicles (ATVs) are reviewed in order to explore the role of experience in accident patterns. Factor attributions made by evaluators from the U.S. Consumer Product Safety Commission were sorted according to the reported ATV experience of the person operating each vehicle at the time of an accident. Counter to some expectations, the proportion of accidents attributed at least in part to each major category (e.g., operator, mechanical, or environmental factors) did not change appreciably with operator experience. In addition, most of the proportions attributed to each of a series of possible operator-related factors did not change, with several generally expected exceptions. Implications for understanding and reducing accidents are considered.

scholarly journals M4 Muscarinic Receptors and Locomotor Activity Regulation

2017 ◽  
pp. S443-S455 ◽  
Author(s):  
J. MYSLIVECEK ◽  
V. FARAR ◽  
P. VALUSKOVA
Keyword(s):  
Locomotor Activity ◽  
Muscarinic Receptors ◽  
Current Evidence ◽  
Special Focus ◽  
Activity Regulation ◽  
Brain Areas ◽  
Hypothalamic Area ◽  
Males And Females ◽  
G Protein Coupled

M4 muscarinic receptors (M4 MR) represent a subfamily of G-protein coupled receptors serving a substantial role in spontaneous locomotor activity regulation, cognition and modulation of cholinergic system. With increasing body of literature discussing the role of M4 MR some controversies arose. Thus, we try here to summarize the current evidence regarding the M4 MR, with the special focus on their role in locomotor activity control. We review the molecular function of M4 MR in specific brain areas implicated in locomotor regulation, and shortly in other CNS processes that could be connected to locomotor activity. We also focus on brain areas implicated in locomotor activity biorhythm changes like suprachiasmatic nucleus, subparaventricular zone posterior hypothalamic area, striatum and thalamus. Gender-related aspects and differences in locomotor activity in males and females are discussed further.

The dual nature of obesity in metabolic programming: quantity versus quality of adipose tissue

2020 ◽  
Vol 134 (18) ◽  
pp. 2447-2451
Author(s):  
Anissa Viveiros ◽  
Gavin Y. Oudit
Keyword(s):  
Adipose Tissue ◽  
Environmental Factors ◽  
Maternal Obesity ◽  
Metabolic Programming ◽  
Dual Nature ◽  
Prevalence Of Obesity ◽  
Adipose Tissue Volume ◽  
Males And Females ◽  
Metabolically Healthy

Abstract The global prevalence of obesity has been rising at an alarming rate, accompanied by an increase in both childhood and maternal obesity. The concept of metabolic programming is highly topical, and in this context, describes a predisposition of offspring of obese mothers to the development of obesity independent of environmental factors. Research published in this issue of Clinical Science conducted by Litzenburger and colleagues (Clin. Sci. (Lond.) (2020) 134, 921–939) have identified sex-dependent differences in metabolic programming and identify putative signaling pathways involved in the differential phenotype of adipose tissue between males and females. Delineating the distinction between metabolically healthy and unhealthy obesity is a topic of emerging interest, and the precise nature of adipocytes are key to pathogenesis, independent of adipose tissue volume.

Questions on the role of biofilms for the adaptation of microorganisms to unfavorable environmental factors by the example of P. aeruginosa

2020 ◽  
Vol 99 (4) ◽  
pp. 379-383
Author(s):  
Vasily N. Afonyushkin ◽  
N. A. Donchenko ◽  
Ju. N. Kozlova ◽  
N. A. Davidova ◽  
V. Yu. Koptev ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Environmental Factors ◽  
Barrier Function ◽  
Infectious Agent ◽  
Antagonistic Activity ◽  
The Body ◽  
Main Function ◽  
Pathogenic Potential ◽  
The Face

Pseudomonas aeruginosa is a widely represented species of bacteria possessing of a pathogenic potential. This infectious agent is causing wound infections, fibrotic cystitis, fibrosing pneumonia, bacterial sepsis, etc. The microorganism is highly resistant to antiseptics, disinfectants, immune system responses of the body. The responses of a quorum sense of this kind of bacteria ensure the inclusion of many pathogenicity factors. The analysis of the scientific literature made it possible to formulate four questions concerning the role of biofilms for the adaptation of P. aeruginosa to adverse environmental factors: Is another person appears to be predominantly of a source an etiological agent or the source of P. aeruginosa infection in the environment? Does the formation of biofilms influence on the antibiotic resistance? How the antagonistic activity of microorganisms is realized in biofilm form? What is the main function of biofilms in the functioning of bacteria? A hypothesis has been put forward the effect of biofilms on the increase of antibiotic resistance of bacteria and, in particular, P. aeruginosa to be secondary in charcter. It is more likely a biofilmboth to fulfill the function of storing nutrients and provide topical competition in the face of food scarcity. In connection with the incompatibility of the molecular radii of most antibiotics and pores in biofilm, biofilm is doubtful to be capable of performing a barrier function for protecting against antibiotics. However, with respect to antibodies and immunocompetent cells, the barrier function is beyond doubt. The biofilm is more likely to fulfill the function of storing nutrients and providing topical competition in conditions of scarcity of food resources.

Role of environmental factors in the etiology of hepatocellular carcinoma

2010 ◽  
Vol 151 (28) ◽  
pp. 1132-1136 ◽  
Author(s):  
István Tornai
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Environmental Factors ◽  
Hepatitis B ◽  
Hepatitis A ◽  
Virus Hepatitis ◽  
B Virus

A krónikus vírushepatitisek jelentik ma a legismertebb okokat a hepatocellularis carcinoma (HCC) kialakulásában. A krónikus B- és C-vírus-hepatitis a májrákok körülbelül 40-50%-át okozza. A nyugati típusú társadalmakban a HCC előfordulása folyamatosan növekvő tendenciát mutat. Az alkohol számít a környezeti tényezők közül a legfontosabbnak, bár az alkoholfogyasztás a legtöbb országban csökken. Ez aláhúzza az egyéb környezeti tényezők fontosságát is. Az elfogyasztott alkoholmennyiséggel egyenes arányban növekszik a cirrhosis és a következményes HCC gyakorisága nőkben és férfiakban egyaránt. A kémiai anyagok közül a legismertebb a Kínában és Afrikában elterjedt aflatoxin, amely a gabonaféléket szennyező mycotoxin. Hasonló területeken endémiás, mint a hepatitis B-vírus, együtt szinergista hatást fejtenek ki. A dohányzás is egyértelműen bizonyított hepatocarcinogen hatással rendelkezik. Ez is jelentősen fokozódik, ha alkoholfogyasztással vagy vírushepatitisszel társul. Társadalmilag talán a legfontosabb az elhízás, a következményes nem alkoholos zsírmáj, illetve steatohepatitis és a 2-es típusú cukorbetegség, amelyek prevalenciája egyre fokozódik. Feltehetően ezek állnak a növekvő HCC-gyakoriság hátterében. Az inzulinrezisztencia és az oxidatív stressz képezik a legfontosabb patogenetikai lépéseket a májsejtkárosodásban. További fontos rizikótényező az orális fogamzásgátlók elterjedt használata. Egyes foglalkozások esetén a tartós szervesoldószer-expozíció is növeli a HCC rizikóját. Védelmet jelenthetnek az antioxidánsok, a szelén, a gyógyszerek közül a statinok és a feketekávé-fogyasztás.

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