scholarly journals Psychological repercussions related to brachytherapy treatment in women with gynecological cancer: analysis of production from 1987 to 2007

2008 ◽  
Vol 16 (6) ◽  
pp. 1049-1053 ◽  
Author(s):  
Gisele Curi de Barros ◽  
Renata Curi Labate
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Literature Review ◽  
Cancer Treatment ◽  
Gynecological Cancer ◽  
Psychological Research ◽  
Psychological Consequences ◽  
Radioactive Materials ◽  
Emotional Issues

One of the radiotherapeutic modalities for gynecological cancer treatment is brachytherapy, characterized by the placement of radioactive materials near the tumor. This treatment can bring side effects for patients. Due to the emotional issues involved, the objective of this research was to apprehend studies about psychological repercussions related to brachytherapy treatment in women with gynecological cancer, through a literature review. The results revealed an embryionic production, with only one study produced in Brazil. A higher concentration of studies was found in the Nursing area. Research focused on psychosocial repercussions, attempting to understand the patients' experiences before, during and after treatment, evidencing physical and psychological consequences that affect their quality of life. It is important to consider the expansion of this production through psychological research that furthers the comprehension about the experience of women submitted to brachytherapy.

scholarly journals When Eating Becomes Torturous: Understanding Nutrition-Related Cancer Treatment Side Effects among Individuals with Cancer and Their Caregivers

Nutrients ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 356
Author(s):  
Brandy-Joe Milliron ◽  
Lora Packel ◽  
Dan Dychtwald ◽  
Cynthia Klobodu ◽  
Laura Pontiggia ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Cancer Treatment ◽  
Food Preferences ◽  
Treatment Side Effects ◽  
Food And Nutrition ◽  
Loss Of Appetite ◽  
Living With Cancer ◽  
Depth Interviews

Individuals living with cancer often experience multiple nutrition-related side effects from cancer treatment, including changes in taste and smell, nausea, diarrhea, loss of appetite, and pain during eating. These side effects can profoundly impact nutritional status and quality of life. The purpose of this study was to explore experiences with nutrition-related cancer treatment side effects among cancer patients and their family caregivers, the way they manage such side effects, and the resulting changes in food preferences and behaviors. Structured surveys and in-depth interviews were conducted. Interviews focused on the presence and management of treatment side effects, how those changes influenced food preferences, and the extent to which they interfered with quality of life. Most patients (72%) reported treatment side effects; 61% reported that these side effects impacted their eating and drinking. Common side effects included fatigue (58%), dry mouth (30%), nausea (24%), constipation (20%) and diarrhea (20%). Six overarching qualitative themes were identified: Spiral of side effects; Pain of eating; Burden of eating; Loss of taste/change in taste; Symptom management; and Solutions. The authors conclude with implications for food and nutrition practice—moving beyond traditional recommendations of what to eat or avoid—to consider the overall patient and caregiver experience.

Gastrointestinal symptoms of pelvic radiation disease (part 1): literature review

2020 ◽  
Vol 18 (2) ◽  
pp. 40-45 ◽  
Author(s):  
Helen Ludlow ◽  
John Green
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Literature Review ◽  
Patient Experience ◽  
Gastrointestinal Symptoms ◽  
Pelvic Radiation ◽  
Gi Symptoms ◽  
Pelvic Cancer ◽  
The Impact

Radiotherapy used to treat cancers in the pelvic region can have lasting side effects, and the persistence of these symptoms for 3 months or more is described as pelvic radiation disease (PRD). The growing number of pelvic cancer patients being diagnosed and successfully treated is increasing the incidence of PRD. This review examines the literature on the gastrointestinal symptoms of PRD. This includes how PRD is defined, how it is identified and how it relates specifically to the three pelvic cancers in which it most commonly manifests (prostate, gynaecological and colorectal). It pays particular attention to the impact of PRD on patient experience and quality of life. This review is the first part in a series on the GI symptoms of PRD.

scholarly journals Short-term fasting accompanying chemotherapy as a supportive therapy in gynecological cancer: protocol for a multicenter randomized controlled clinical trial

Trials ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Daniela Koppold-Liebscher ◽  
Christian S. Kessler ◽  
Nico Steckhan ◽  
Vanessa Bähr ◽  
Cornelia Kempter ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Tumor Progression ◽  
Gynecological Cancer ◽  
Controlled Clinical Trial ◽  
Breast Cancer Patients ◽  
Short Term ◽  
Randomized Controlled ◽  
Refined Carbohydrates

Abstract Background/objectives A few preliminary studies have documented the safety and feasibility of repeated short-term fasting in patients undergoing chemotherapy. However, there is a lack of data from larger randomized trials on the effects of short-term fasting on quality of life, reduction of side effects during chemotherapy, and a possible reduction of tumor progression. Moreover, no data is available on the effectiveness of fasting approaches compared to so-called healthy diets. We aim to investigate whether the potentially beneficial effects of short-term fasting can be confirmed in a larger randomized trial and can compare favorably to a plant-based wholefood diet. Methods This is a multicenter, randomized, controlled, two-armed interventional study with a parallel group assignment. One hundred fifty patients, including 120 breast cancer patients and 30 patients with ovarian cancer, are to be randomized to one of two nutritional interventions accompanying chemotherapy: (1) repeated short-term fasting with a maximum energy supply of 350–400 kcal on fasting days or (2) repeated short-term normocaloric plant-based diet with restriction of refined carbohydrates. The primary outcome is disease-related quality of life, as assessed by the functional assessment of the chronic illness therapy measurement system. Secondary outcomes include changes in the Hospital Anxiety and Depression Score and as well as frequency and severity of chemotherapy-induced side effects based on the Common Terminology Criteria of Adverse Events. Explorative analysis in a subpopulation will compare histological complete remissions in patients with neoadjuvant treatments. Discussion/planned outcomes Preclinical data and a small number of clinical studies suggest that repeated short-term fasting may reduce the side effects of chemotherapy, enhance quality of life, and eventually slow down tumor progression. Experimental research suggests that the effects of fasting may partly be caused by the restriction of animal protein and refined carbohydrates. This study is the first confirmatory, randomized controlled, clinical study, comparing the effects of short-term fasting to a short-term, plant-based, low-sugar diet during chemotherapy on quality of life and histological tumor remission. Trial registration ClinicalTrials.gov NCT03162289. Registered on 22 May 2017

The Effect of Lumbar Sympathetic Ganglion Block on Gynecologic Cancer-Related Lymphedema

2013 ◽  
Vol 4;16 (4;7) ◽  
pp. 345-352
Author(s):  
Hahck Soo Park
Keyword(s):  
Quality Of Life ◽  
Conservative Treatment ◽  
Cancer Treatment ◽  
Pain Score ◽  
Lower Limb ◽  
Sympathetic Ganglion ◽  
Gynecological Cancer ◽  
Gynecologic Cancer ◽  
Ganglion Block

Background: Eighteen to 25% of patients after gynecological cancer treatment suffer from lower limb lymphedema (LLL) that decreases the quality of life of gynecological cancer survivors. Lumbar sympathetic ganglion block (LSGB) is widely used in practice for the evaluation and management of sympathetically mediated pain in the lower limbs. Several articles have suggested that sympathetic ganglion block could be an effective treatment for lymphedema. Objectives: To investigate the effect of LSGB on patients with secondary lymphedema related to the treatment of gynecologic cancer, who do not respond to a conservative treatment. Study Design: Prospective clinical study. Setting: A single academic medical center, outpatient setting. Methods: Eighteen patients with stage II lower limb lymphedema who did not response to the conservative treatment were recruited. The patients underwent fluoroscopy-guided LSGB 3 times at 2-week intervals. The circumference of the thigh and calf was measured in the upright position at the first visit and 2 weeks after each session of LSGB. The pain score of the lower limb was checked at the same time by a numeric rating scale (NRS) from 0 to 10. The patients were asked about their satisfaction with the procedure at the last follow-up visit. The Wilcoxon signed rank test was used for data analysis. Significance was accepted at a P-value less than 0.05/3. Results: The circumferences of affected thighs and calves decreased from 56.38 ± 4.77 and 35.33 ± 3.51cm to 54.42 ± 5.27 and 34.41 ± 3.35cm, respectively, in a significant manner after 3 consecutive LSGBs (P < 0.05/3). The maximal decrease after the third LSGB was 4 cm in the thigh and 2cm in the calf. The pain score also showed a significant decrease after 3 consecutive LSGBs from 2.17 to 1.28. The tightness and heaviness of the affected limb decreased after the first LSGB in 15 patients (83.3%) and after the second LSGB in 2 patients (11.1%). Five of 18 patients (27.8%) answered that the result of the LSGB met their expectations, 10 (55.6%) answered they would undergo the same treatment for the same outcome, 2 (11.1%) answered they did not improve as much as they had hoped, and they would not undergo the same treatment for the same outcome, and only one patient (5.6%) answered the LSGB showed no effect. Limitations: This study lacks a placebo control group and has only 18 patients. We did not evaluate the quality of life of the patients. Conclusion: We suggest that LSGB can be one of the treatment options for patients suffering from LLL after gynecologic cancer treatment. Our result could provide a basis for a randomized controlled trial in future investigations. The pain physicians can play an important role as one of the multidisciplinary team for a comprehensive treatment of LLL. Key words: Lumbar sympathetic ganglion block;gynecologic cancer;lymphedema

scholarly journals PHYSICAL ACTIVITY AND QUALITY OF LIFE IN WOMEN WITH BREAST CANCER – A CROSS-SECTIONAL STUDY

2018 ◽  
Vol 24 (5) ◽  
pp. 377-381
Author(s):  
Leonessa Boing ◽  
Gustavo Soares Pereira ◽  
Melissa de Carvalho Souza Vieira ◽  
Taysi Seemann ◽  
Allana Alexandre Cardoso ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Activity ◽  
Side Effects ◽  
Cancer Treatment ◽  
Vigorous Physical Activity ◽  
Breast Cancer Treatment ◽  
Clinical Treatment ◽  
Walking Time

ABSTRACT Introduction: Breast cancer treatment can cause different side effects on the quality of life of women. Physical activity, in turn, can reduce these side effects. Objective: To investigate the physical activity and quality of life of women during and after breast cancer treatment. Methods: Sample of 174 women (57.0±9.5 years) during or after clinical treatment for breast cancer. Interview questionnaire composed of general information, physical activity (IPAQ short version) and quality of life (EORTC QLQ-C30 and BR23). For statistical analysis chi-squared test or Fisher's exact test, student's t-test for independent samples, Mann-Whitney U test and multiple logistic regression analyses (p <0.05). Results: Most women did not achieve the physical activity guidelines, particularly those undergoing clinical treatment. Results showed longer walking time, moderate physical activity, vigorous physical activity, moderate + vigorous physical activity, and total physical activity among the women following completion of treatment. The quality of life scores were also higher among women after clinical treatment. Logistic regression indicated that every 10-minute increment to walking time results in a 19% decrease in the probability of worse functional capacity and a 26% decrease in the probability of worse symptoms associated with treatment side effects. Conclusion: During treatment, women with breast cancer undertake less physical activity and have worse quality of life. Walking appears to be an effective type of physical activity for these women, improving quality of life during and after breast cancer treatment. Level of evidence II; Prognostic studies - Investigation of the effect of patient characteristics on the disease outcome.

scholarly journals Fungsi Tiroid Pasca Radioterapi Tumor Ganas Kepala- Leher

2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Ade Chandra ◽  
Sukri Rahman
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Side Effects ◽  
Thyroid Gland ◽  
Literature Review ◽  
Head And Neck ◽  
Blood Vessels ◽  
Neck Cancer ◽  
Thyroid Function Tests

Abstrak                 Latar Belakang : Radioterapi merupakan salah satu pilihan modalitas pada penatalaksanaan tumor ganas kepala dan leher selain pembedahan dan kemoterapi. Radioterapi pada tumor ganas kepala dan leher dapat mempengaruhi kelenjar tiroid dan merangsang kelainan. Diantara efek samping akibat radioterapi pada kelenjar tiroid tersebut, hipotiroid merupakan kelainan yang paling sering ditemukan. Hipotiroid akibat radioterapi ini bersifat irreversibel dan mempengaruhi kualitas hidup pasien.  Tujuan : Untuk mengetahui fungsi tiroid setelah dilakukan radioterapi pada pasien tumor ganas kepala dan leher. Tinjauan Pustaka : Hipotiroid merupakan efek samping yang paling sering ditemukan pasca radioterapi tumor ganas kepala dan leher. Kelainan pada tiroid pasca radioterapi dihubungkan dengan kerusakan sel dan pembuluh darah kecil kelenjar tiroid serta fibrosis kapsul kelenjar tiroid yang selanjutnya menyebabkan kelenjar tiroid mengecil. Kesimpulan : Radioterapi pada pasien tumor ganas kepala dan leher dapat menimbulkan efek samping berupa hipotiroid yang dibuktikan dengan peningkatan nilai TSH dan penurunan nilai T4  pada pemeriksaan fungsi tiroid.Kata kunci: Radioterapi, tumor ganas kepala dan leher, hipotiroid AbstractBackground: Radiotherapy is one option of modality in the management of head and neck cancer beside surgery and chemotherapy. Radiotherapy in the head and neck cancer can affect the thyroid gland and stimulates the gland disorders. Among the side-effects of radiotherapy on the thyroid gland, hypothyroidism is a disorder most commonly found. Hypothyroidism due to radiotherapy is irreversible and affect quality of life of patients Objective: To determine the function of the thyroid after radiotherapy in patients with the head and neck cancer. Literature Review: Hypothyroidism is the most common side effects found after radiotherapy of the head and neck cancer. Abnormalities of the thyroid after radiotherapy is associated with damage cells and small blood vessels of the thyroid gland and capsule fibrosis of the thyroid gland which in turn causes the thyroid gland to shrink. Conclusion: Radiotherapy in patients with the head and neck cancer can cause side effects such as hypothyroidism as evidenced by the increase in the value of TSH and T4 in the impairment of thyroid function tests. Keywords:  Radiotherapy, head and neck cancer, hypothyroid

scholarly journals Aspects of interest related to antiemesis in haematological patients

2019 ◽  
Vol 7 (2) ◽  
pp. 46-48
Author(s):  
Maria Perfecta Fernandez Gonzalez ◽  
Aurea Maria Gomez Marquez ◽  
Maria Pereiro Sanchez ◽  
Raquel Iglesias Varela ◽  
Jose Luis Sastre Moral  ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Radiation Therapy ◽  
Clinical Practice ◽  
Side Effects ◽  
Cancer Treatment ◽  
Negative Impact ◽  
Nausea And Vomiting ◽  
Haematological Patients ◽  
Critical Aspects

Few side effects of cancer treatment are more fearsome for patients than nausea and vomiting. Although both can result from surgery or radiation therapy, chemotherapy-induced nausea and vomiting (CINV) are potentially the most severe and the most distressing ones. Despite recent advances in the prevention of emesis induced by chemotherapy, its control remains to be insufficient in 20-25%.1s of patients, with the ensuing negative impact on their quality of life. In this small review, we intend to analyze some critical aspects related to the approach of antiemetic therapy in the clinical practice in haematological patients.

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