Effects of Hydroxyapatite on Titanium Foam as a Bone Ingrowth Surface in Acetabular Shells: A Canine Study

2010 ◽  
Vol 20 (1) ◽  
pp. 35-42 ◽  
Author(s):  
William M. Mihalko ◽  
Craig Howard ◽  
Fred Dimaano ◽  
Nena Dimaano ◽  
Monica Hawkins
Keyword(s):  
Bone Ingrowth ◽  
Titanium Foam ◽  
Canine Study

Effect of nickel on formation of transition layer during liquid-phase aluminizing of titanium

2020 ◽  
pp. 313-317
Author(s):  
A.I. Kovtunov ◽  
Yu.Yu. Khokhlov ◽  
S.V. Myamin
Keyword(s):  
Mechanical Properties ◽  
Liquid Phase ◽  
Intermetallic Layer ◽  
Reaction Diffusion ◽  
Strength Properties ◽  
Effect Of Temperature ◽  
Nickel Concentration ◽  
Aluminum Melt ◽  
Titanium Aluminum ◽  
Titanium Foam

Titanium—aluminum, titanium—foam aluminum composites and bimetals obtained by liquid-phase methods, are increasingly used in industry. At the liquid-phase methods as result of the reaction diffusion of titanium and aluminum is formed transitional intermetallic layer at the phase boundary of the composite, which reduces the mechanical properties of titanium and composite. To reduce the growth rate of the intermetallic layer between the layers of the composite and increase its mechanical properties, it is proposed to alloy aluminum melt with nickel. The studies of the interaction of titanium and molten aluminum alloyed with nickel made it possible to establish the effect of temperature and aluminizing time on the thickness, chemical and phase compositions of the transition intermetallic layer. The tests showed the effect of the temperature of the aluminum melt, the nickel concentration on the strength properties of titanium—aluminum bimetal.

scholarly journals Osseointegration Improvement of Co-Cr-Mo Alloy Produced by Additive Manufacturing

Pharmaceutics ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 724
Author(s):  
Amilton Iatecola ◽  
Guilherme Arthur Longhitano ◽  
Luiz Henrique Martinez Antunes ◽  
André Luiz Jardini ◽  
Emilio de Castro Miguel ◽  
...  
Keyword(s):  
Surface Modification ◽  
Additive Manufacturing ◽  
Bone Ingrowth ◽  
Orthopedic Implants ◽  
Coated Sample ◽  
High Mechanical Strength ◽  
Coated Surface ◽  
Surface Modification Techniques ◽  
Almost All ◽  
Cobalt Base

Cobalt-base alloys (Co-Cr-Mo) are widely employed in dentistry and orthopedic implants due to their biocompatibility, high mechanical strength and wear resistance. The osseointegration of implants can be improved by surface modification techniques. However, complex geometries obtained by additive manufacturing (AM) limits the efficiency of mechanical-based surface modification techniques. Therefore, plasma immersion ion implantation (PIII) is the best alternative, creating nanotopography even in complex structures. In the present study, we report the osseointegration results in three conditions of the additively manufactured Co-Cr-Mo alloy: (i) as-built, (ii) after PIII, and (iii) coated with titanium (Ti) followed by PIII. The metallic samples were designed with a solid half and a porous half to observe the bone ingrowth in different surfaces. Our results revealed that all conditions presented cortical bone formation. The titanium-coated sample exhibited the best biomechanical results, which was attributed to the higher bone ingrowth percentage with almost all medullary canals filled with neoformed bone and the pores of the implant filled and surrounded by bone ingrowth. It was concluded that the metal alloys produced for AM are biocompatible and stimulate bone neoformation, especially when the Co-28Cr-6Mo alloy with a Ti-coated surface, nanostructured and anodized by PIII is used, whose technology has been shown to increase the osseointegration capacity of this implant.

Osteoclast and osteoblast response to strontium-doped struvite coatings on titanium for improved bone integration

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Claus Moseke ◽  
Katharina Wimmer ◽  
Markus Meininger ◽  
Julia Zerweck ◽  
Cornelia Wolf-Brandstetter ◽  
...  
Keyword(s):  
Bone Ingrowth ◽  
Osteoclast Differentiation ◽  
Inhibitory Effect ◽  
Osteoclast Formation ◽  
Strontium Nitrate ◽  
Bone Implant ◽  
Electrochemically Deposited ◽  
Bone Integration ◽  
Titanium Substrates

AbstractTo develop implants with improved bone ingrowth, titanium substrates were coated with homogeneous and dense struvite (MgNH4PO4·6H2O) layers by means of electrochemically assisted deposition. Strontium nitrate was added to the coating electrolyte in various concentrations, in order to fabricate Sr-doped struvite coatings with Sr loading ranging from 10.6 to 115 μg/cm2. It was expected and observed that osteoclast activity surrounding the implant was inhibited. The cytocompatibility of the coatings and the effect of Sr-ions in different concentrations on osteoclast formation were analyzed in vitro. Osteoclast differentiation was elucidated on morphological, biochemical as well as on gene expression level. It could be shown that moderate concentrations of Sr2+ had an inhibitory effect on osteoclast formation, while the growth of osteoblastic cells was not negatively influenced compared to pure struvite surfaces. In summary, the electrochemically deposited Sr-doped struvite coatings are a promising approach to improve bone implant ingrowth.

The Modified Maquet Procedure (MMP) in Dogs: Technical Development and Initial Clinical Experience

2016 ◽  
Vol 52 (4) ◽  
pp. 242-250 ◽  
Author(s):  
Malcolm Graham Ness
Keyword(s):  
Cruciate Ligament ◽  
Major Complication ◽  
Tibial Tuberosity ◽  
Radiographic Examination ◽  
Computer Assisted ◽  
Clinical Report ◽  
Modified Technique ◽  
Cranial Cruciate Ligament ◽  
Titanium Foam

ABSTRACT The literature about tibial tuberosity advancement surgery in dogs and humans informed the development of a version of the operation using a wedge-shaped implant of titanium foam. Computer-assisted drawing and stereolithography was used to create instruments and implants that were evaluated by cadaver surgery. A trial, involving 26 client-owned dogs with lameness due to cranial cruciate ligament failure, was started. Follow-up was done by clinical and radiographic examination after 4 wk and clinical examination again 6–11 mo after surgery. The titanium foam implant maintained tibial tuberosity advancement easily and effectively. The same major complication occurred in 2 of the first 6 cases before, a slightly modified technique was used to treat 20 dogs without complication. At mid-term follow-up (6–11 mo), 20/26 dogs (77%) had returned to full function, two dogs (7.7%) had acceptable function, two dogs (7.7%) could not be evaluated due to recent contra lateral modified Maquet procedure surgery, and two (7.7%) dogs had died for reasons unrelated to the study. This is the first clinical report of the use of titanium foam in veterinary orthopaedics. Modified Maquet procedure appears to be an effective treatment for lameness due to failure of the cranial cruciate ligament in dogs.

Bone ingrowth in total knee arthroplasty: The impact of HA-coatings and the relation with mechanical stability

1998 ◽  
Vol 31 ◽  
pp. 26
Author(s):  
L. Labey ◽  
H. Van Campenhout ◽  
J. Vander Sloten ◽  
R. Van Audekercke ◽  
G. Van der Perre ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Mechanical Stability ◽  
Bone Ingrowth ◽  
Total Knee ◽  
The Impact

scholarly journals Treatment of acute vocal fold scar with local injection of basic fibroblast growth factor: a canine study

2010 ◽  
Vol 130 (7) ◽  
pp. 844-850 ◽  
Author(s):  
Atsushi Suehiro ◽  
Shigeru Hirano ◽  
Yo Kishimoto ◽  
Bernard Rousseau ◽  
Tatsuo Nakamura ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Vocal Fold ◽  
Local Injection ◽  
Fibroblast Growth ◽  
Vocal Fold Scar ◽  
Canine Study

Porous Bioceramics (Open Cell Foams) Expanded in Vacuum

2006 ◽  
Vol 309-311 ◽  
pp. 1023-1026
Author(s):  
E.T. Uzumaki ◽  
C.S. Lambert
Keyword(s):  
Zirconium Oxide ◽  
Cell Structure ◽  
The Body ◽  
Carbon Coatings ◽  
Open Cell ◽  
Glass Foam ◽  
Open Cell Foams ◽  
Titanium Foam ◽  
Porous Bioceramics ◽  
Scanning Electron

In this study, porous bioceramics (titanium foam with diamond-like carbon coatings, glass foam and zirconium oxide foam) were produced using expansion in vacuum. The porosity, the pore size and pore morphology can be adjusted in agreement with the application. The different 3D structures were obtained by varying the parameters of the process. The microstructure and morphology of the porous materials were observed by scanning electron microscopy (SEM) and optical microscopy. The foam exhibit an open-cell structure with interconnected macropores, which provide the potential for tissue ingrowths and the transport of the body fluids.

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