Dynamic changes in Tangxunhu wetland over a period of rapid development (1953–2005) in Wuhan, China

Wetlands ◽  
2009 ◽  
Vol 29 (4) ◽  
pp. 1255-1261 ◽  
Author(s):  
Kai Xu ◽  
Chunfang Kong ◽  
Chonglong Wu ◽  
Gang Liu ◽  
Hongbin Deng ◽  
...  
2019 ◽  
Vol 316 (2) ◽  
pp. L303-L320 ◽  
Author(s):  
Kolene E. Bailey ◽  
Michael L. Floren ◽  
Tyler J. D’Ovidio ◽  
Steven R. Lammers ◽  
Kurt R. Stenmark ◽  
...  

Chronic pulmonary diseases, including idiopathic pulmonary fibrosis (IPF), pulmonary hypertension (PH), and chronic obstructive pulmonary disease (COPD), account for staggering morbidity and mortality worldwide but have limited clinical management options available. Although great progress has been made to elucidate the cellular and molecular pathways underlying these diseases, there remains a significant disparity between basic research endeavors and clinical outcomes. This discrepancy is due in part to the failure of many current disease models to recapitulate the dynamic changes that occur during pathogenesis in vivo. As a result, pulmonary medicine has recently experienced a rapid expansion in the application of engineering principles to characterize changes in human tissues in vivo and model the resulting pathogenic alterations in vitro. We envision that engineering strategies using precision biomaterials and advanced biomanufacturing will revolutionize current approaches to disease modeling and accelerate the development and validation of personalized therapies. This review highlights how advances in lung tissue characterization reveal dynamic changes in the structure, mechanics, and composition of the extracellular matrix in chronic pulmonary diseases and how this information paves the way for tissue-informed engineering of more organotypic models of human pathology. Current translational challenges are discussed as well as opportunities to overcome these barriers with precision biomaterial design and advanced biomanufacturing techniques that embody the principles of personalized medicine to facilitate the rapid development of novel therapeutics for this devastating group of chronic diseases.


2021 ◽  
Vol 29 (1) ◽  
pp. 49-56
Author(s):  
Nataliya V. Kurkan ◽  

The article addresses basic genre parameters of the operations manual and aims to develop its genre model within engineering discourse. Engineering communication is becoming a subject of a special focus for linguists due to its rapid development driven by dynamic changes in technology, society and industry, which results in continuous exchange of information between the members of the engineering society. Despite the significant number of studies in the field of certain institutional discourses, the genre structure of engineering discourse, one of the promising fields of communicative linguistics, is still a research challenge due to insufficient studies of the engineering discourse as well as the professional communication in general. Since discourse is embodied in certain genres, and genres, in turn, are always included into a certain discourse field, the author proposes the idea that the engineering discourse provides a number of core genres which reflect the values, strategies and information of engineering communication. The research is based on the texts of operations manuals for the equipment produced by Russian manufacturers. The analysis of genre parameters and lexical aspects has revealed a number of key characteristics of the operations manual as well as its peculiar linguistic presentation as of a specific genre of engineering communication. The analysis proves that the operation manual genre meets the primary goal of professional communication in the engineering field. The peculiar characteristics of the studied genre are determined by the professional communicative purposes and the situation. The results of the research may be used in university lectures on professional communication, cognitive linguistics and cognitive terminology studies.


2018 ◽  
Vol 10 (8) ◽  
pp. 2863 ◽  
Author(s):  
Caizhi Sun ◽  
Ling Liu ◽  
Yanting Tang

Inclusive growth captures the need to alleviate the problems of global income disparity and poverty, particularly in Asia. The study’s goal is to construct an indicator system that measures the inclusive growth of 11 coastal provinces and cities in China from five aspects, namely, survival, capacity, development, freedom, and opportunity, examining the area from 2000 to 2015. The system is based on Bossel’s basic orientor indicator framework. Dynamic changes in overall levels in the five fields are investigated and spatial differences calculated using the Gini coefficient. Among the provinces, Guangxi shows the strongest survival conditions, giving it an advantage over other regions. Shanghai has the highest level of capacity and freedom. Guangdong has the strongest development momentum, but this appears to be weakening. Finally, Shandong shows many more social opportunities. The study suggests that inclusive growth in the area has increased as a result of the area’s rapid development, but the growth rates remain low. The level of inclusive growth shows a large gap across the regions. Gini coefficient differences show that the eastern coastal areas have strong development trends, whereas the northern and southern coastal areas show weaker ones. We also offer suggestions on how to promote inclusive growth in these regions.


2020 ◽  
Vol 80 (6) ◽  
pp. 113-126
Author(s):  
Нелля Григорівна Ничкало ◽  
Наталія Петрівна Муранова ◽  
Олена Станіславівна Волярська ◽  
Наталія Валентинівна Пазюра

The issue of the use of educational communications in university students’ training and prospects of their development in the digital society have been analyzed. The methodological basis for the study of prognostic aspects of modernization of educational communications is the combination of systematic, axiological, cultural and individual-oriented approaches. The aim of the paper is to carry out theoretical analysis of the issue and experimentally confirm the effectiveness of educational communications in psychological, pedagogical, social, economic and technological aspects. The analysis of modern philosophic and pedagogical studies of Ukrainian and foreign scholars demonstrated that the development and innovative use of educational communications is influenced by globalization and integrative processes, dynamic changes on international, national and regional labour markets, intensive implementation of informational support, rapid development of commercial activity and the sphere of educational services, including online services. The pedagogical experiment carried out at the National Aviation University, Ukraine, has verified the effectiveness of integrated use of educational communications in distant education. The result of the study proved that the development, modernization and use of educational communications are determined by the following factors: flexibility of educational communications and their orientation towards society requirements; their forward-looking character and focus on dynamic changes in all social, economic and industrial spheres, taking into account digitalization and new educational requirements of different segments of population connected with it; modernization of teaching content, forms, technologies and methods in different educational subsystems; equal access to quality education for all segments of population in the country. The approaches to pedagogical forecasting, development, modernization and the use of educational communications on national, regional and field levels have been offered. It has been found out that upgrading educational communications in the digitized society requires modernization of legislation in view of foreign and domestic innovative experience, increasing demands of employers, educational establishments of different levels of accreditation, state employment service and educational requirements of different segments of population.


Electronics ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 507
Author(s):  
Chengxiang Liu ◽  
Wei Xiong ◽  
Ying Zhang ◽  
Yang Sun ◽  
Minghui Xiong ◽  
...  

With the rapid development of communications technology, the space-based information network (SBIN) is increasingly threatened by the outside world. Dynamic changes in any part of its interior can cause the collapse of the entire network. Therefore, research on the invulnerability of SBIN has become an urgent need to promote the economic development of our country and improve the living standards of our people. To this end, this paper has carried out research on the node-attacked invulnerability of SBIN based on the complex network theory. First, based on the model of SBIN, the internal parameters of the network are analyzed theoretically based on complex networks. Second, the paper proposes an improved tree attack strategy to analyze the invulnerability of SBIN, which constitutes a problem where the traditional attack strategy has a low invulnerability and the connected edge cannot fully realize the network function. Then, based on the improved tree attack strategy algorithm, this paper optimizes the invulnerability of SBIN by constructing four different edge-increasing strategies. Through the research, the LDF edge-increasing strategy makes the entire network flatter and can effectively improve the network’s ability to resist destruction. The research of invulnerability based on the complex network has a certain technical support and theoretical guidance for the construction of a reasonable and stable SBIN.


2016 ◽  
Vol 51 (1) ◽  
pp. 103-116
Author(s):  
Daniela Gračan

In the mid-70s of the last century, due to changes in the marketing strategy and repositioning of the entire sector on the market, the demand for cruise tourism experienced growth. One of the reasons for the relatively rapid development of the market of cruise tourism was conquering new segments of consumers and the development of new concepts of cruise that offers rest and relaxation with a variety of activities and entertainment on board. Cruising has evolved into a major worldwide corporate business, and the dynamic changes in the reorganization of major cruise corporation went up with the high growth rates in demand on the world cruise market. The main objective of the reorganization of these large corporations is contained in adapting to the needs of tourists on cruise ships, trying to adjust the offer to growing demand - to its multi-functional and multi-disciplinary nature. Today, the dominating business and scientific-economic concept is a marketing approach in which the consumer-tourist is in the center of attention.


Author(s):  
T. M. Murad ◽  
Karen Israel ◽  
Jack C. Geer

Adrenal steroids are normally synthesized from acetyl coenzyme A via cholesterol. Cholesterol is also shown to enter the adrenal gland and to be localized in the lipid droplets of the adrenal cortical cells. Both pregnenolone and progesterone act as intermediates in the conversion of cholesterol into steroid hormones. During pregnancy an increased level of plasma cholesterol is known to be associated with an increase of the adrenal corticoid and progesterone. The present study is designed to demonstrate whether the adrenal cortical cells show any dynamic changes during pregnancy.


Author(s):  
James C. Long

Over the years, many techniques and products have been developed to reduce the amount of time spent in a darkroom processing electron microscopy negatives and micrographs. One of the latest tools, effective in this effort, is the Mohr/Pro-8 film and rc paper processor.At the time of writing, a unit has been recently installed in the photographic facilities of the Electron Microscopy Center at Texas A&M University. It is being evaluated for use with TEM sheet film, SEM sheet film, 35mm roll film (B&W), and rc paper.Originally designed for use in the phototypesetting industry, this processor has only recently been introduced to the field of electron microscopy.The unit is a tabletop model, approximately 1.5 × 1.5 × 2.0 ft, and uses a roller transport method of processing. It has an adjustable processing time of 2 to 6.5 minutes, dry-to-dry. The installed unit has an extended processing switch, enabling processing times of 8 to 14 minutes to be selected.


2020 ◽  
Vol 13 (4) ◽  
pp. 1132-1153 ◽  
Author(s):  
Tianpei Zhou ◽  
Nan Zhang ◽  
Changzheng Wu ◽  
Yi Xie

Surface/interface nanoengineering of electrocatalysts and air electrodes will promote the rapid development of high-performance rechargeable Zn–air batteries.


2004 ◽  
Vol 71 ◽  
pp. 121-133 ◽  
Author(s):  
Ascan Warnholtz ◽  
Maria Wendt ◽  
Michael August ◽  
Thomas Münzel

Endothelial dysfunction in the setting of cardiovascular risk factors, such as hypercholesterolaemia, hypertension, diabetes mellitus and chronic smoking, as well as in the setting of heart failure, has been shown to be at least partly dependent on the production of reactive oxygen species in endothelial and/or smooth muscle cells and the adventitia, and the subsequent decrease in vascular bioavailability of NO. Superoxide-producing enzymes involved in increased oxidative stress within vascular tissue include NAD(P)H-oxidase, xanthine oxidase and endothelial nitric oxide synthase in an uncoupled state. Recent studies indicate that endothelial dysfunction of peripheral and coronary resistance and conductance vessels represents a strong and independent risk factor for future cardiovascular events. Ways to reduce endothelial dysfunction include risk-factor modification and treatment with substances that have been shown to reduce oxidative stress and, simultaneously, to stimulate endothelial NO production, such as inhibitors of angiotensin-converting enzyme or the statins. In contrast, in conditions where increased production of reactive oxygen species, such as superoxide, in vascular tissue is established, treatment with NO, e.g. via administration of nitroglycerin, results in a rapid development of endothelial dysfunction, which may worsen the prognosis in patients with established coronary artery disease.


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