PLASMA CONCENTRATION OF TESTOSTERONE IN YOUNG BULLS IN RELATION TO AGE, RATE OF WEIGHT GAIN AND STIMULATION WITH HUMAN CHORIONIC GONADOTROPHIN

1980 ◽  
Vol 86 (3) ◽  
pp. 465-469 ◽  
Author(s):  
ANNE SUNDBY ◽  
WEIERT VELLE
Keyword(s):  
Weight Gain ◽  
Correlation Coefficients ◽  
Multiple Correlation Coefficient ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Daily Weight Gain ◽  
Plasma Testosterone ◽  
Testosterone Concentration ◽  
Subsequent Decrease ◽  
The Difference

In 86 bulls ranging in age between 3 and 11 months, the maximal plasma testosterone concentration (n = 7) well as the mean concentration (n = 7, same samples) were found to increase with age to peak values at 7–8 months with a subsequent decrease. The multiple correlation coefficient for monthly gain as a function of testosterone concentration and age was 0·85 (P <0·001), for monthly gain as a function of age 0·84 (P <0·001) and for monthly gain as a function of testosteroneconcentration 0·44 (P <0·001). The deviation in levels of measured plasma testosterone from the curve expressed by multiple regression analyses of testosterone concentration as a function of age was correlated with the average daily weight gain during the testing period of 9 months and found to be not significant (r = 0·21). The difference between concentrations of plasma testosterone after stimulation with human chorionic gonadotrophin (HCG) and the spontaneous maximal concentration of this hormone was not significant. High correlation coefficients were found between maximal (r = 0·8) and mean (r = 0·6) concentrations of plasma testosterone before and after an injection of HCG (P <0·001).

SHORT-TERM EFFECTS OF COPULATION, HUMAN CHORIONIC GONADOTROPHIN INJECTION AND NON-TACTILE ASSOCIATION WITH A FEMALE ON TESTOSTERONE LEVELS IN THE MALE RAT

1974 ◽  
Vol 60 (3) ◽  
pp. 429-439 ◽  
Author(s):  
K. PURVIS ◽  
N. B. HAYNES
Keyword(s):  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Physical Contact ◽  
Male Rats ◽  
Male Rat ◽  
Plasma Testosterone ◽  
Short Term ◽  
Testosterone Levels ◽  
Peripheral Plasma ◽  
First Contact

SUMMARY Peripheral plasma testosterone levels in the male rat were increased above control levels 5 min after the first intromission with an oestrous female, or 8–10 min after first contact with the female. The levels remained raised for at least 30 min if copulation was allowed to continue. Intravenous injection of human chorionic gonadotrophin resulted in an increased peripheral concentration of plasma testosterone after 10–15 min and an increase of testosterone content of the testis 5–10 min after injection, indicating that the rat testis has a potential to respond rapidly to gonadotrophin. The results suggested that if the testosterone surge during copulation was gonadotrophin-dependent, it was initiated before the first intromission. Indeed, plasma testosterone levels were raised in male rats 5 min after being placed in the proximity of oestrous females but not allowed physical contact.

THE EFFECT OF INTRAVENOUSLY ADMINISTERED HUMAN CHORIONIC GONADOTROPHIN ON PLASMA LEVELS OF TESTOSTERONE AND 5α-DIHYDROTESTOSTERONE IN NORMAL MALE SUBJECTS

1973 ◽  
Vol 72 (3) ◽  
pp. 615-624 ◽  
Author(s):  
W. Maurer ◽  
U. Volkwein ◽  
J. Tamm
Keyword(s):  
Plasma Levels ◽  
Initial Phase ◽  
Plasma Concentrations ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Plasma Testosterone ◽  
Normal Male ◽  
Peripheral Conversion ◽  
Male Subjects

ABSTRACT HCG was infused intravenously into normal male subjects. The doses administered were 500, 100 and 50 IU, respectively. During the initial phase of the infusions the plasma testosterone (T) levels decreased. Thirty minutes after starting the infusion of 500 and 100 IU HCG, respectively, the plasma testosterone increased. Significantly elevated values were observed 60 to 180 minutes after the cessation of HCG administration. The dihydrotestosterone (DHT) concentrations in the plasma showed a varying pattern. On the average this steroid also exhibited an increase in plasma following the HCG administration. From the results no conclusions can be drawn as to the extent to which the plasma concentrations of DHT have been influenced by a secretion from the testes or by a peripheral conversion of T into DHT.

Penggunaan Konsentrat Komersial (683) untuk Memacu Pertambahan Berat Badan Kambing Kacang yang Diberi Pakan Dasar Hijauan Campuran

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Januar Akmal Swanda ◽  
Didy Rachmadi ◽  
Asril Asril
Keyword(s):  
Weight Gain ◽  
Analysis Of Variance ◽  
Latin Square ◽  
Daily Weight Gain ◽  
Feed Consumption ◽  
Feed Conversion ◽  
Anova Analysis ◽  
Significant Difference ◽  
The Difference ◽  
Banda Aceh

Abstrak. Penggunaan konsentrat komersial (683) untuk memacu pertambahan berat badan kambing kacang yang diberi pakan dasar hijauan campuran telah dilakukan di Laboratorium Ilmu dan Teknologi Ternak Potong Program Studi Peternakan Fakultas Pertanian Universitas Syiah Kuala Banda Aceh. pada bulan Agustus sampai dengan Oktober 2017. Tujuan penelitian ini adalah untuk mengetahui pertambahan berat badan harian pada kambing kacang jantan yang diberikan kosentrat komersial (683) dan hijauan campuran. Rancangan yang digunakan dalam penelitian ini adalah Rancangan Bujur Sangkar Latin (RBSL) yaitu dengan menggunakan empat perlakuan dan empat periode (ulangan). Masing-masing perlakuan adalah pelakuan A (0% pellet 683) perlakuan B (20% pellet 683), perlakuan C (40% pellet 683), dan pelakuan D (60% pellet 683). Data penelitian yang diperoleh dianalisis menggunakan ANOVA (Analysis of Variance). Parameter yang diamati adalah : Pertambahan berat badan, Konsumsi pakan, Konversi pakan. Hasil penelitian menunjukkan perbedaan yang sangat nyata (P0.01) terhadap konsumsi ransum. Namun terjadi perbedaan yang tidak nyata (P0,05) pada parameter pertambahan berat badan dan efesiensi ransum. Use of Commercial Concentrates (683) to Stimulate Weight Loss of Goat kacang Provided with Basic Mixed Forage FeedAbstract. The use of commercial concentrate 683 to accelerate the growth of kacang goat fed with mixed forage has been conducted at the Laboratory of Technology and Livestock Production, the Faculty of Agriculture, Syiah Kuala University of Banda Aceh. from August to October 2017. The objective of this study was to determine the daily weight gain in kacang goat given commercial concentrate (683) and mixed green. The design used in this study was Latin Square Design (RBSL) wash four treatments and four periods (replication). The treatment ware A (0% pellet 683) B (20% pellet 683), C (40% pellet 683), and D (60% pellet 683). The data obtained were analyzed using ANOVA (Analysis of Variance). Parameters observed were: Weight gain, Feed consumption, Feed conversion. The results showed a significant difference on (P 0.01) to the consumption of rations. However, the difference was not significant (P 0.05) on the parameter of weight gain and ration efficiency. 

Effect of intraventricular injection of 5,6-dihydroxytryptamine on spermatogenesis and plasma testosterone levels in the rat

1985 ◽  
Vol 106 (3) ◽  
pp. 395-NP ◽  
Author(s):  
T. K. Das ◽  
R. Mazumder ◽  
N. M. Biswas
Keyword(s):  
Quantitative Evaluation ◽  
Wistar Rats ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Seminiferous Epithelium ◽  
Intraventricular Injection ◽  
Plasma Testosterone ◽  
Testosterone Levels ◽  
Testicular Steroidogenesis

ABSTRACT Quantitative evaluation of spermatogenesis at stage VII of the cycle of the seminiferous epithelium and radioimmunoassay of plasma testosterone were performed in adult Wistar rats after intraventricular injection of 5,6-dihydroxytryptamine (5,6-DHT). The rats were killed 2, 10 and 21 days after injection. Brain 5-hydroxytryptamine (5-HT) and plasma testosterone levels were found to be significantly lower in all rats treated with 5,6-DHT. A significant reduction in step 7 spermatid count was also observed after 10 and 21 days. Supplementation with human chorionic gonadotrophin for 21 days in rats injected with 5,6-DHT partially prevented the step 7 spermatid degeneration and increased testosterone levels without producing any effect on brain concentrations of 5-HT. These results suggest that changes in testicular steroidogenesis and spermatogenesis are secondary to pituitary gonadotrophin release which, in turn, is under the influence of brain 5-HT neurones. J. Endocr. (1985) 106, 395–400

THE EFFECT OF THE URINARY GONADOTROPHIN INHIBITOR ON THE RAT UTERINE WEIGHT RESPONSE TO HUMAN CHORIONIC GONADOTROPHIN

1970 ◽  
Vol 64 (3) ◽  
pp. 421-430
Author(s):  
L. J. Hipkin
Keyword(s):  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Hormone Release ◽  
Uterine Weight ◽  
Control Groups ◽  
Mouse Uterus ◽  
Final Body Weight ◽  
Gonadotrophin Secretion ◽  
Small Doses ◽  
The Difference

ABSTRACT A urinary extract (GIM), which previously had been shown to inhibit small doses of human chorionic gonadotrophin (HCG) in the mouse uterus assay, was tested in the rat. In this species, GIM caused an increase in the basal uterine weight and potentiated the response to 0.1 IU HCG. Similar results, and in addition augmentation of the activity of 0.2 IU HCG, were obtained in rats injected with carbon tetrachloride or starved. GIM inhibited the activity of 0.8 IU and 1.6 IU HCG. This was thought to result from the difference in mean final body weight between the GIM and the control groups. The results support the hypothesis that GIM causes a non-specific stress reaction. In rats the effect of this is to increase endogenous gonadotrophin secretion. This contrasts with the results previously reported for mice, which suggest that stress suppresses endogenous follicle-stimulating hormone release.

EFFECT OF GLUCOCORTICOIDS ON PLASMA TESTOSTERONE IN MEN

1978 ◽  
Vol 89 (1) ◽  
pp. 126-131 ◽  
Author(s):  
G. Schaison ◽  
F. Durand ◽  
I. Mowszowicz
Keyword(s):  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Plasma Testosterone ◽  
Acth Stimulation ◽  
Testosterone Levels ◽  
Before And After ◽  
The Mean ◽  
Normal Men ◽  
Lh Secretion ◽  
Dexamethasone Suppression

ABSTRACT ACTH decreases plasma testosterone levels in men. The aim of this study was to assess the part played by the glucocorticoids in this effect, and the mechanism of their action. Plasma androstenedione, testosterone, cortisol and LH were measured in 8 normal men, before and after the following tests: ACTH stimulation (2 mg im), metyrapone administration (500 mg/every 4 h/6 times) and dexamethasone suppression (8 mg/day/3 days). In addition, androstenedione and testosterone were evaluated under human chorionic gonadotrophin (5000 IU HCG/day/3 days) before and after dexamethasone suppression (8 mg/day/6 days). In all patients, ACTH decreased plasma testosterone from 5.87 ± 1.59 (sd) ng/ml to 3.06 ± 0.8 (sd) ng/ml (P < 0.001). In contrast, after metyrapone, the mean plasma testosterone was increased to 6.98 ± 1.75 (sd) ng/ml. This increase, though not statistically significant, was observed in all patients but one. Both tests resulted in a significant increase of plasma androstenedione (P < 0.01 and P < 0.001, respectively). Dexamethasone suppressed both testosterone and androstenedione levels. None of the three tests had a significant effect on the LH concentration. HCG injection increased the mean plasma testosterone to 11.46 ± 2.80 ng/ml. Dexamethasone significantly depressed (P < 0.01) the testosterone response to HCG. These data are consistent with the following conclusions: 1) The decrease of plasma testosterone levels, observed in men after ACTH administration, is not observed after metyrapone induced ACTH increase. This confirms that it is related to cortisol levels rather than to ACTH itself. 2) Glucocorticoids act directly on testicular biosynthesis since they do not induce any change in LH secretion and since dexamethasone reduces testosterone response to HCG.

scholarly journals Normal Growth of Healthy Infants Born from HIV+ Mothers Fed a Reduced Protein Infant Formula Containing the Prebiotics Galacto-Oligosaccharides and Fructo-Oligosaccharides: A Randomized Controlled Trial

2015 ◽  
Vol 9 ◽  
pp. CMPed.S17841
Author(s):  
Hugo Da Costa Ribeiro Júnior ◽  
Tereza Cristina Medrado Ribeiro ◽  
Angela Peixoto De Mattos ◽  
Mariana Pontes ◽  
Roseli Oselka Saccardo Sarni ◽  
...  
Keyword(s):  
Weight Gain ◽  
Infant Formula ◽  
Controlled Trial ◽  
Normal Growth ◽  
Daily Weight Gain ◽  
Term Infants ◽  
Intention To Treat ◽  
Formula Group ◽  
The Difference ◽  
Breast Fed

Objective The aim of the current study was to evaluate the safety of a new reduced protein (2.1 g/100 kcal) infant formula containing 4 g/L of 90% galacto-oligosaccharides (GOS) and 10% fructo-oligosaccharides (FOS). Methods Healthy term infants from Brazil were enrolled. Those born to human immunodeficiency virus (HIV)-positive mothers were randomized to a test ( n = 65) or control ( n = 63) formula group. Infants born to HIV-negative mothers were either exclusively breast-fed ( n = 79) or received a mixed diet (breast milk and test formula, n = 65). Between 2 weeks and 4 months of age, infants were exclusively fed according to their assigned group. Anthropometric measurements were taken at baseline, 1, 2, 3, 4, 6, 8, 10, and 12 months. Digestive tolerance was evaluated during the first 4 months. The primary outcome was mean daily weight gain between 2 weeks and 4 months in the test formula and breast-fed groups. Results Data from all infants ( N = 272) were used in the intention-to-treat (ITT) analysis and data from 230 infants were used in the per-protocol (PP) analysis. The difference in mean daily weight gain between 2 weeks and 4 months in the test formula and breast-fed groups was 1.257 g/day (onesided 95% confidence interval [CI]: -0.705 to inf, P < 0.001) in the PP analysis, showing that the lower bound of the 95% CI was above the -3.0 g/day non-inferiority margin. Results were similar in the ITT analysis. Symptoms of digestive tolerance and frequency of adverse events were similar in the two groups. Conclusions The formula containing 2.1 g/100 kcal protein and GOS and FOS was safe and tolerated well.

VIRILIZING ADRENOCORTICAL ADENOMA RESPONSIVE TO GONADOTROPHIN

1975 ◽  
Vol 78 (1) ◽  
pp. 77-85 ◽  
Author(s):  
M. Blichert-Toft ◽  
H. Vejlsted ◽  
H. Kehlet ◽  
R. Albrechtsen
Keyword(s):  
Young Female ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Adrenocortical Function ◽  
Plasma Testosterone ◽  
Adrenocortical Adenoma ◽  
Androgen Excess ◽  
Pronounced Increase ◽  
Steroid Excretion ◽  
Trophic Hormones

ABSTRACT A virilizing adrenocortical adenoma was demonstrated in a young female. Urinary 17-ketosteroid excretion and subfractions, plasma testosterone level and urinary 17-ketogenic steroid excretion were markedly increased. Dehydroepiandrosterone was the main constituent of the androgen excess. Otherwise the adrenocortical function was found to be normal as evaluated from measurements of cortisol, corticosterone and their metabolites under basal conditions and during dynamic tests. The androgen excess showed an unexpected response to trophic hormones. Human chorionic gonadotrophin stimulation resulted in a pronounced increase in androgen production, whereas no gonadotrophin-dependency could be demonstrated by means of the oestrogen suppression test. Similarly, no corticotrophin-dependency could be demonstrated by corticotrophin stimulation and suppression tests. Removal of the tumour resulted in normalization of the androgen production and no abnormal response upon human chorionic gonadotrophin administration could now be found. The inappropriate response of tumours to trophic hormones is discussed. It is concluded that the reliability of stimulation and suppression tests in determining the site of excessive androgen production should be accepted with reservation.

scholarly journals Semi-Intensive Fattening Suitability and Slaughter Value of Young Bulls of Three Polish Native Breeds in Comparison With Polish Holstein-Friesian and Simmental

2014 ◽  
Vol 14 (2) ◽  
pp. 453-460 ◽  
Author(s):  
Zygmunt Litwińczuk ◽  
Paweł Żółkiewski ◽  
Mariusz Florek ◽  
Witold Chabuz ◽  
Piotr Domaradzki
Keyword(s):  
Weight Gain ◽  
Reference Group ◽  
Daily Weight Gain ◽  
White Variety ◽  
Black And White ◽  
Holstein Friesian ◽  
Good Material ◽  
Fattening Period ◽  
The Difference ◽  
Intensive System

Abstract An evaluation was conducted of the suitability for fattening in a semi-intensive system (mainly with fodders from permanent grassland) and the slaughter value of 15 young bulls of the Polish Red (PR) breed and 10 each of the White-Backed (WB) and Polish Black-and-White (BW) breeds. The reference group consisted of young bulls of the Black-and-White variety of the Polish Holstein- Friesian (HF) breed and the Simmental (SIM) breed, fattened on the same farms. Control fattening was carried out until the age of 18 months. Mean daily weight gain in the bulls of the native breeds during the control fattening period (which lasted 314-358 days) was 0.9 kg, similarly to HF, but significantly lower (P≤0.05) than in the Simmentals (986 g). During the entire fattening period, i.e. from birth to the age of 18 months, daily weight gain was 832 g in PR and 889-919 g in WB and BW. Dressing percentage was lowest in PR bulls (51.69%), and higher in WB (53.1%) and BW (53.49%), with values similar to the reference group, i.e. young bulls of the Simmental (52.97%) and HF (53.29%) breeds. The difference between PR and BW (1.8%) and HF (1.6%) was statistically significant (P≤0.05). In the EUROP classification system, the carcasses of the young bulls of the native breeds were most often placed in classes R- and O+ (conformation) and 2+ and 3- (fat cover), as in the case of young HF bulls. Carcasses of young Simmental bulls were assigned to much higher classes. The young bulls of the three Polish native breeds evaluated are good material for fattening in a semi-intensive system (mainly with fodder from permanent grasslands), while the young PR bulls were the least suitable

Sign in / Sign up

Export Citation Format

Share Document