scholarly journals Effects of aging on regular and express latencies of vergence

2009 ◽  
Vol 1 (3) ◽  
Author(s):  
Qing Yang ◽  
Thanh-Thuan Le ◽  
Zoi Kapoula
Keyword(s):  
Eye Movements ◽  
Target Onset ◽  
Aging Effects ◽  
Median Line ◽  
Fixed Stimulus ◽  
Convergence And Divergence ◽  
Young Subjects ◽  
Voluntary Eye Movements ◽  
Effects Of Aging ◽  
Gap Paradigm

Vergence eye movements are frequent in every day life and important for depth perception. Yet, studies of vergence in elderly are rare. We examined convergence and divergence between targets placed along median line at 20, 40 or 150cm. Thirteen elderly (70±11years) and ten young (25±3years) adults participated in the study. The gap paradigm (i.e., the fixed stimulus is extinguished prior to target onset) and the overlap paradigm (the fixed stimulus remains illuminated after target onset) were used to elicit reflexive or voluntary eye movements. Latency of convergence and divergence increased with age in both gap and overlap conditions. Both young subjects and elderly showed shorter latency of vergence under the gap condition than under the overlap condition. In the overlap condition, for elderly only, convergence resulted in longer latencies than divergence. In the gap condition express convergence was rare, while express latencies (80–120ms) were frequent for divergence starting from a near fixation point (at 20cm). The rates of express divergence were similar for young (23%) and elderly (21%). These results were in line with prior studies of saccades and indicated different aging effects on regular and express latencies.

Effects of Aging on the Subcortical Encoding of Stop Consonants

2020 ◽  
Vol 29 (3) ◽  
pp. 391-403
Author(s):  
Dania Rishiq ◽  
Ashley Harkrider ◽  
Cary Springer ◽  
Mark Hedrick
Keyword(s):  
Older Adults ◽  
Repeated Measures ◽  
Mixed Model ◽  
Auditory Brainstem ◽  
Auditory Brainstem Responses ◽  
Aging Effects ◽  
Formant Frequency ◽  
Place Of Articulation ◽  
Second Formant ◽  
Effects Of Aging

Purpose The main purpose of this study was to evaluate aging effects on the predominantly subcortical (brainstem) encoding of the second-formant frequency transition, an essential acoustic cue for perceiving place of articulation. Method Synthetic consonant–vowel syllables varying in second-formant onset frequency (i.e., /ba/, /da/, and /ga/ stimuli) were used to elicit speech-evoked auditory brainstem responses (speech-ABRs) in 16 young adults ( M age = 21 years) and 11 older adults ( M age = 59 years). Repeated-measures mixed-model analyses of variance were performed on the latencies and amplitudes of the speech-ABR peaks. Fixed factors were phoneme (repeated measures on three levels: /b/ vs. /d/ vs. /g/) and age (two levels: young vs. older). Results Speech-ABR differences were observed between the two groups (young vs. older adults). Specifically, older listeners showed generalized amplitude reductions for onset and major peaks. Significant Phoneme × Group interactions were not observed. Conclusions Results showed aging effects in speech-ABR amplitudes that may reflect diminished subcortical encoding of consonants in older listeners. These aging effects were not phoneme dependent as observed using the statistical methods of this study.

Age Differences in Eye Movements During Reading: Degenerative Problems or Compensatory Strategy?

2019 ◽  
Vol 24 (4) ◽  
pp. 297-311
Author(s):  
José David Moreno ◽  
José A. León ◽  
Lorena A. M. Arnal ◽  
Juan Botella
Keyword(s):  
Eye Movements ◽  
Eye Movement ◽  
Meta Analysis ◽  
Age Groups ◽  
Behavioral Changes ◽  
Aging Effects ◽  
Movement Data ◽  
Sentence Reading ◽  
The Difference ◽  
Eye Movements During Reading

Abstract. We report the results of a meta-analysis of 22 experiments comparing the eye movement data obtained from young ( Mage = 21 years) and old ( Mage = 73 years) readers. The data included six eye movement measures (mean gaze duration, mean fixation duration, total sentence reading time, mean number of fixations, mean number of regressions, and mean length of progressive saccade eye movements). Estimates were obtained of the typified mean difference, d, between the age groups in all six measures. The results showed positive combined effect size estimates in favor of the young adult group (between 0.54 and 3.66 in all measures), although the difference for the mean number of fixations was not significant. Young adults make in a systematic way, shorter gazes, fewer regressions, and shorter saccadic movements during reading than older adults, and they also read faster. The meta-analysis results confirm statistically the most common patterns observed in previous research; therefore, eye movements seem to be a useful tool to measure behavioral changes due to the aging process. Moreover, these results do not allow us to discard either of the two main hypotheses assessed for explaining the observed aging effects, namely neural degenerative problems and the adoption of compensatory strategies.

Effects of aging and noncanonical form presentation on idiom processing: Evidence from eye tracking

2020 ◽  
pp. 1-27
Author(s):  
Katja I. Haeuser ◽  
Shari Baum ◽  
Debra Titone
Keyword(s):  
Older Adults ◽  
Eye Movements ◽  
Eye Tracking ◽  
Healthy Aging ◽  
Idiom Comprehension ◽  
First Pass ◽  
Effects Of Aging ◽  
Open Question ◽  
Idiom Processing ◽  
Noncanonical Form

Abstract Comprehending idioms (e.g., bite the bullet) requires that people appreciate their figurative meanings while suppressing literal interpretations of the phrase. While much is known about idioms, an open question is how healthy aging and noncanonical form presentation affect idiom comprehension when the task is to read sentences silently for comprehension. Here, younger and older adults read sentences containing idioms or literal phrases, while we monitored their eye movements. Idioms were presented in a canonical or a noncanonical form (e.g., bite the iron bullet). To assess whether people integrate figurative or literal interpretations of idioms, a disambiguating region that was figuratively or literally biased followed the idiom in each sentence. During early stages of reading, older adults showed facilitation for canonical idioms, suggesting a greater sensitivity to stored idiomatic forms. During later stages of reading, older adults showed slower reading times when canonical idioms were biased toward their literal interpretation, suggesting they were more likely to interpret idioms figuratively on the first pass. In contrast, noncanonical form presentation slowed comprehension of figurative meanings comparably in younger and older participants. We conclude that idioms may be more strongly entrenched in older adults, and that noncanonical form presentation slows comprehension of figurative meanings.

scholarly journals Anti-aging properties of metformin

2021 ◽  
Vol 11 (9) ◽  
pp. 37-42
Author(s):  
Anna Małgorzata Łopuszyńska ◽  
Mateusz Pawlicki ◽  
Magdalena Kozioł ◽  
Aleksandra Krasa ◽  
Ewa Piekarska ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Randomized Trials ◽  
Aging Effect ◽  
Oral Drug ◽  
Aging Effects ◽  
Ampk Signaling ◽  
Anti Cancer ◽  
Aging Properties ◽  
Effects Of Aging

 Introduction: Life expectancy of human population is being constantly prolonged, hence there is a lot of research into drug that will prevent the effects of aging. There are many reports that metformin, which is a drug used in type 2 diabetes, has anti-aging effects. It belongs to the group of biguanides and has been used since the 1950s. It is a relatively safe, cheap and effective drug, which makes it a promising subject for many studies. The purpose of this review is to present the latest developments in this field. Material and methods: PubMed scientific base was searched using following keywords: metformin, aging, anti-aging, in years 2017-2021. Results: Numerous studies show that metformin has an impact on aging through the nutrient pathway, AMPK signaling pathway, and its effects on reactive oxygen species. In addition, it has an anti-cancer effect, inhibiting, among others, rectal cancer cells and p53 mutant colon cancer. Research in rodents has shown that this drug has anti-aging effects on many organs, including the CNS, ovaries, prostate, heart muscle and skin. Conclusions: Metformin, which is the most commonly used oral drug in type 2 diabetes, has many other mechanisms of action. Its anti-aging effect works on many organs in our bodies, which gives hope to find an anti-aging substance. However, multicentre, randomized trials are needed to determine the exact anti-aging dose, its possible side effects, and effects on various organisms. 

Recasting the Smooth Pursuit Eye Movement System

2004 ◽  
Vol 91 (2) ◽  
pp. 591-603 ◽  
Author(s):  
Richard J. Krauzlis
Keyword(s):  
Eye Movements ◽  
Brain Stem ◽  
Smooth Pursuit ◽  
Visual Motion ◽  
Saccadic Eye Movements ◽  
Extrastriate Cortex ◽  
High Acuity ◽  
Voluntary Eye Movements ◽  
New Perspective ◽  
The Brain

Primates use a combination of smooth pursuit and saccadic eye movements to stabilize the retinal image of selected objects within the high-acuity region near the fovea. Pursuit has traditionally been viewed as a relatively automatic behavior, driven by visual motion signals and mediated by pathways that connect visual areas in the cerebral cortex to motor regions in the cerebellum. However, recent findings indicate that this view needs to be reconsidered. Rather than being controlled primarily by areas in extrastriate cortex specialized for processing visual motion, pursuit involves an extended network of cortical areas, and, of these, the pursuit-related region in the frontal eye fields appears to exert the most direct influence. The traditional pathways through the cerebellum are important, but there are also newly identified routes involving structures previously associated with the control of saccades, including the basal ganglia, the superior colliculus, and nuclei in the brain stem reticular formation. These recent findings suggest that the pursuit system has a functional architecture very similar to that of the saccadic system. This viewpoint provides a new perspective on the processing steps that occur as descending control signals interact with circuits in the brain stem and cerebellum responsible for gating and executing voluntary eye movements. Although the traditional view describes pursuit and saccades as two distinct neural systems, it may be more accurate to consider the two movements as different outcomes from a shared cascade of sensory–motor functions.

Whiplash Effects on Brain: Voluntary Eye Movements

2014 ◽  
pp. 233-239
Author(s):  
M. Spanio ◽  
S. Rigo ◽  
D. C. Alpini
Keyword(s):  
Eye Movements ◽  
Voluntary Eye Movements

scholarly journals Investigation of Temperature and Aging Effects in Nanostructured Dye Solar Cells Studied by Electrochemical Impedance Spectroscopy

2009 ◽  
Vol 2009 ◽  
pp. 1-15 ◽  
Author(s):  
Minna Toivola ◽  
Janne Halme ◽  
Lauri Peltokorpi ◽  
Peter Lund
Keyword(s):  
Solar Cells ◽  
Electrochemical Impedance Spectroscopy ◽  
Impedance Spectroscopy ◽  
Electrochemical Impedance ◽  
Charge Transfer Resistance ◽  
Aging Effects ◽  
Transfer Resistance ◽  
Deterioration Rate ◽  
Dye Solar Cells ◽  
Effects Of Aging

Effects of aging and cyclically varying temperature on the electrical parameters of dye solar cells were analyzed with electrochemical impedance spectroscopy. Photoelectrode total resistance increased as a function of time due to increasing electron transport resistance in theTiO2film. On the other hand, photoelectrode recombination resistance was generally larger, electron lifetimes in theTiO2were film longer, and charge transfer resistance on the counter electrode was smaller after the temperature treatments than before them. These effects correlated with the slower deterioration rate of the temperature-treated cells, in comparison to the reference cells.

scholarly journals Voluntary Spatial Attention has Different Effects on Voluntary and Reflexive Saccades

2003 ◽  
Vol 3 ◽  
pp. 881-902 ◽  
Author(s):  
Stephanie K. Seidlits ◽  
Tammie Reza ◽  
Kevin A. Briand ◽  
Anne B. Sereno
Keyword(s):  
Eye Movements ◽  
Spatial Attention ◽  
Saccadic Eye Movements ◽  
Fundamental Issue ◽  
Fixation Condition ◽  
The Subject ◽  
Symbolic Cues ◽  
The Relationship ◽  
Reflexive Saccades ◽  
Gap Paradigm

Although numerous studies have investigated the relationship between saccadic eye movements and spatial attention, one fundamental issue remains controversial. Some studies have suggested that spatial attention facilitates saccades, whereas others have claimed that eye movements are actually inhibited when spatial attention is engaged. However, these discrepancies may be because previous research has neglected to separate and specify the effects of attention for two distinct types of saccades, namely reflexive (stimulus-directed) and voluntary (antisaccades). The present study explored the effects of voluntary spatial attention on both voluntary and reflexive saccades. Results indicate that voluntary spatial attention has different effects on the two types of saccades. Antisaccades were always greatly facilitated following the engagement of spatial attention by symbolic cues (arrows) informing the subject where the upcoming saccade should be directed. Reflexive saccades showed little or no cueing effects and exhibited significant facilitation only when these cues were randomly intermixed with uncued trials. In addition, the present study tested the effects of fixation condition (gap, step, and overlap) on attentional modulation. Cueing effects did not vary due to fixation condition. Thus, voluntary spatial attention consistently showed different effects on voluntary and reflexive saccades, and there was no evidence in these studies that voluntary cues inhibit reflexive saccades, even in a gap paradigm.

scholarly journals Effects of aging on eye movements in the real world

2015 ◽  
Vol 9 ◽  
Author(s):  
Stefan Dowiasch ◽  
Svenja Marx ◽  
Wolfgang Einhäuser ◽  
Frank Bremmer
Keyword(s):  
Eye Movements ◽  
Real World ◽  
The Real ◽  
Effects Of Aging
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