scholarly journals INFLUENCE OF ANTHROPOGENIC AND NATURAL FACTORS ON THE CONTENT OF POLLUTANT METALS IN MEDICINAL PLANTS OF THE MIDDLE PRE-URAL REGION (ZAKURYE ISLAND IN CHUSOVOY)

2020 ◽  
pp. 152-165
Author(s):  
Alexander D. Solovyev ◽  
◽  
Marina G. Shcherban ◽  
Maria D. Plotnikova ◽  
◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Raw Materials ◽  
Research Work ◽  
Significant Degree ◽  
World Health ◽  
Plant Materials ◽  
River Bank ◽  
Deep Layers ◽  
Health Organization

According to the estimates of the World Health Organization, the share of medications based on medicinal plant materials is increasing from year to year. Along with industrial drugs, the population widely uses medicinal plants harvested on their own. However, medicinal plants growing in unfavorable environmental conditions can cause serious harm to health. Thus, it is necessary not only to control raw materials but also to study the areas where harvested medicinal plants grow, which in most cases are located in the immediate vicinity of industrial facilities. The purpose of this work was a comprehensive study of the ecological state of Zakurye Island in the town of Chusovoy and its plant communities. When planning the research work, the study area was zoned in accordance with the distance from the alleged source of pollution. In the process of work, we used standard methods of preparation and drying of medicinal plant materials, sampling of soil and water. Chemical analysis was carried out with the use of generally accepted and approved methods. A conclusion is made about a significant degree of pollution with pollutant metals of the surface and deep layers of the Chusovaya River, as well as of soil and medicinal plants near Zakurye Island. Most likely, environmental pollution is associated with poorly maintained dumps of blast-furnace slag from the Chusovoy Metallurgical Plant, located along the river bank.

scholarly journals Ethnobotanical Study of Cultivated Plants in Kaišiadorys District, Lithuania: Possible Trends for New Herbal Based Medicines

2019 ◽  
Vol 2019 ◽  
pp. 1-15 ◽  
Author(s):  
Zivile Pranskuniene ◽  
Kristina Ratkeviciute ◽  
Zenona Simaitiene ◽  
Andrius Pranskunas ◽  
Jurga Bernatoniene
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
World Health Organization ◽  
World Health ◽  
Cultivated Plants ◽  
Ethnobotanical Study ◽  
Artemisia Absinthium ◽  
Plant Materials ◽  
The World ◽  
Health Organization

Background. Despite the growing body of ethnobotanical studies in Europe, publications are scarce in Lithuania. Ethnobotanical study in Kaišiadorys district is one of the few from this field done in Lithuania. Lithuania is divided into five ethnographic regions, and Kaišiadorys district is an area which borders with the three of them (Aukštaitija, Dzūkija, and Suvalkija), which determines the ethnographic distinctiveness of the area. The aim of this study was to determine the occurrence of cultivated medicinal plants, their families and pharmaceutical forms used in Kaišiadorys district, Lithuania, and to assess the conformity of medicinal plant materials used by respondents with the recommendations for medicinal plant materials in the World Health Organization monographs. Methods. The field work was conducted in periods of time from July 2016 to October 2017. During this ethnobotanical research, 30 people were interviewed, 25 of whom agreed to communicate. The average age of respondents was 65 years. Information was collected using semistructured and structured interviews. The obtained information was recorded indicating ethnic names of plants, their preparation techniques, parts used, modes of administration, and application for therapeutic purposes. Results. Respondents mentioned 71 species of cultivated medicinal plants from 38 families, used for therapeutic purposes and indicated which parts of the plant they use, how they prepare them, indications for use, and ways of administration. The most commonly cited families were Asteraceae (20.5%), Lamiaceae (13.9%), and Apiaceae (12.8%); most popular plants, cited more than 20 times, were Tilia cordata L., Matricaria recutita L., Calendula officinalis L., Carum carvi L., and Artemisia absinthium L. The frequently used plant parts were flowers (mentioned 35.8%), leaves (16.3%), roots and tubers (16.1%), herb (14.8%), and seeds (7.0%). Diseases most frequently treated were digestive (21.5% of citations), respiratory (21.3 % of citations), mental and behavioral (11.0%) disorders, certain infections and parasitic diseases (10.1%), and diseases of genitourinary system (9.1%). Conclusions. Only 19 of the cultivated medicinal plant species mentioned by interviewed persons are described in the World Health Organization monographs. This means that the remaining 52 species are used without the World Health Organization approved medical indications, based solely on the folk medicine knowledge and experience. This study showed that the folk use of plants is strongly rooted in daily practice in the studied area.

scholarly journals Determination of essential and non-essential elements in Xylanthemum macropodum of Balochistan, Pakistan

2021 ◽  
Vol 2 (02) ◽  
pp. 94-103
Author(s):  
Maria Bibi ◽  
Samiullah Khan ◽  
Attiq-Ur-Rehman Kakar ◽  
Naqeebullah Khan ◽  
Abdul Hakeem Tareen ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Atomic Absorption ◽  
Essential Elements ◽  
Permissible Limit ◽  
World Health ◽  
Home Remedy ◽  
The World ◽  
Health Organization

Background: Medicinal plants have been used to treat various diseases for several years throughout the world. Xylanthemum macropodum is a medicinal plant with a vast application as a home remedy in Balochistan. Objective: The current study was conducted to determine the levels of essential and non-essential elements in Xylanthemum macropodum collected from Quetta (Balochistan, Pakistan). Methods: Analysis was conducted for eleven elements by using atomic absorption spectrophotometer and flame photometer. Results: The essential and non-essential elements that were detected in Xylanthemum macropodum are K, Na, Ca, Fe, Cu, Co, Ni, Mn, Cr, Cd and Pb, respectively. The result of the concentration of determined elements are in the order of K> Na> Ca> Fe> Cu> Co> Ni> Mn> Cd> Cr> Pb in Xylanthemum macropodum 3000> 1600> 790.25> 92.36> 85.31> 49.24> 40.94> 20.94> 6.655> 1.61> 1.18 µg/g respectively. Conclusions: Mn, Na and Pb were found within the permissible limit given by World Health Organization, while Ca, Cu, Fe, Ni, Cd and Cr were beyond the permissible limits. However, there is no permissible limit for K and Co.

scholarly journals Production de matières premières et fabrication des médicaments à base de plantes médicinales

2021 ◽  
Vol 15 (2) ◽  
pp. 750-772
Author(s):  
Salfo Ouedraogo ◽  
Jules Yoda ◽  
Tata Kadiatou Traore ◽  
Mathieu Nitiema ◽  
Bavouma C. Sombie ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Raw Materials ◽  
Production Quality ◽  
World Health ◽  
Plantes Médicinales ◽  
African Countries ◽  
Production Quality Control ◽  
Advance Research ◽  
Health Organization ◽  
Active Substances

Les plantes constituent un réservoir pour les pharmacopées du monde. Plusieurs médicaments importants sont fabriqués à partir des substances actives d’origine végétales. En outre de nombreux médicaments modernes ont été fabriqués à partir de ces matières premières. Les plantes médicinales sont utilisées directement sous forme fraîche, sèche ou transformée, stabilisée, ou extrait ou formulée avec d’autres plantes ou excipients de synthèse. Dans tous les cas, la matière végétale utilisée pour fabriquer la forme posologique doit faire preuve de son efficacité, son innocuité et être de qualité conforme aux exigences de la Pharmacopée Européenne pour les phytomédicaments, garantissant ainsi sa sécurité d’emploi. Pour ce faire, l’Organisation Mondiale de la Santé (OMS) a mis à la disposition des états membres des guides et standards permettant d’harmoniser et de sécuriser leur utilisation. Ainsi de nombreux pays africains ont adopté ces outils après des modifications appropriées pour faire progresser la recherche et le développement (R&D) de médicaments à base de plante. Le but de ce travail était de faire une synthèse des différentes étapes de production, de contrôle qualité et de  standardisation des matières premières issues des plantes médicinales et des médicaments à base de plantes médicinales.Mots clés : Pharmacopée, médicaments, médecine traditionnelle, sécurité d’emploi, phytomédicaments. English title: Production of raw materials and manufacturing of drugs from medicinal plants Plants are a reservoir for the world's pharmacopoeias. Several important medicines are made from active substances of plant origin. In addition, many modern medicines have been made from these raw materials. Medicinal plants are used directly in fresh, dry or processed, stabilized, or extracted form or formulated with other plants or synthetic excipients. In all cases, the herbal material used to manufacture the dosage form must demonstrate its efficacy, safety and be of a quality that meets the requirements of the European Pharmacopoeia for phytomedicines, thus ensuring its safe use. To this end, the World Health Organization (WHO) has made available to Member States guides and standards to harmonize and secure their use. Thus, many African countries have adopted these tools after appropriate modifications to advance research and development (R&D) of plant-based drugs. The aim of this work was to make a synthesis of the different stages of production, quality control and standardization of raw materials from medicinal plants and herbal medicines.Keywords: Pharmacopoeia, drugs, traditional medicine, safe use, phytomedicines.

Natural products from the traditional Moroccan pharmacopoeia: A potential lead for the prevention and treatment of COVID-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1278-1285
Author(s):  
Mohamed Yafout ◽  
Amine Ousaid ◽  
Ibrahim Sbai El Otmani ◽  
Youssef Khayati ◽  
Amal Ait Haj Said
Keyword(s):  
Medicinal Plants ◽  
Plant Extracts ◽  
Molecular Mechanisms ◽  
Scientific Literature ◽  
Treatment Protocol ◽  
World Health ◽  
The World ◽  
Health Organization ◽  
Promising Source

The new SARS-CoV-2 belonging to the coronaviruses family has caused a pandemic affecting millions of people around the world. This pandemic has been declared by the World Health Organization as an international public health emergency. Although several clinical trials involving a large number of drugs are currently underway, no treatment protocol for COVID-19 has been officially approved so far. Here we demonstrate through a search in the scientific literature that the traditional Moroccan pharmacopoeia, which includes more than 500 medicinal plants, is a fascinating and promising source for the research of natural molecules active against SARS-CoV-2. Multiple in-silico and in-vitro studies showed that some of the medicinal plants used by Moroccans for centuries possess inhibitory activity against SARS-CoV or SARS-CoV-2. These inhibitory activities are achieved through the different molecular mechanisms of virus penetration and replication, or indirectly through stimulation of immunity. Thus, the potential of plants, plant extracts and molecules derived from plants that are traditionally used in Morocco and have activity against SARS-CoV-2, could be explored in the search for a preventive or curative treatment against COVID-19. Furthermore, safe plants or plant extracts that are proven to stimulate immunity could be officially recommended by governments as nutritional supplements.

scholarly journals The Safety Assessment of Toxic Metals in Commonly Used Herbs, Spices, Tea, and Coffee in Poland

2021 ◽  
Vol 18 (11) ◽  
pp. 5779
Author(s):  
Grażyna Kowalska
Keyword(s):  
Heavy Metals ◽  
Environmental Protection Agency ◽  
Inductively Coupled Plasma ◽  
Raw Materials ◽  
Hazard Quotient ◽  
World Health Organisation ◽  
World Health ◽  
Target Hazard Quotient ◽  
Plant Materials

The presented study was aimed at the determination of the level of contamination with heavy metals (Cd, Pb, As, and Hg) in 240 samples of plant materials, i.e., herbal raw materials, spices, tea, and coffee. Moreover, a probabilistic risk assessment (noncarcinogenic and carcinogenic risks) was estimated by models including target hazard quotient (THQ) and cancer risk (CR). The samples were subjected to microwave mineralisation with the use of HNO3 (65%), while the determination of the content of the elements was performed with the use of inductively coupled plasma mass spectrometer (ICP–MS) and a mercury analyser. The element which was characterised by the highest level of accumulation in the analysed samples was lead (from 0.010 to 5.680 mg/kg). Among the heavy metals under analysis, the lowest concentration was noted in the case of mercury (from 0.005 to 0.030 mg/kg). A notably higher level of contamination with heavy metals was noted in the analysed samples of herbs and spices (0.005–5.680 mg/kg), compared to samples of tea and coffee (0.005–0.791 mg/kg). According to the guidelines of the World Health Organisation (WHO) concerning the limits of contamination of samples of herbal raw materials with heavy metals, lead levels exceeding the limits were only noted in 24 samples of herbs (18%). In all of the analysed samples of spices, tea, and coffee, no instances of exceeded limits were noted for any of the analysed heavy metals. The values of TTHQmax (in relation to the consumption of the analysed products) were as follows: up to 4.23 × 10−2 for spices, up to 2.51 × 10−1 for herbs, up to 4.03 × 10−2 for China tea, and up to 1.25 × 10−1 for roasted coffee beans. As the value of THQ ≤1, there is no probability of the appearance of undesirable effects related to the consumption of the analysed group of raw materials and products of plant origin. The CR value for As (max. value) was 1.29 × 10−5, which is lower than the maximum acceptable level of 1 × 10−4 suggested by United States Environmental Protection Agency (USEPA).

scholarly journals Assessment of Antimalarial Activity againstPlasmodium falciparumand Phytochemical Screening of Some Yemeni Medicinal Plants

2009 ◽  
Vol 6 (4) ◽  
pp. 453-456 ◽  
Author(s):  
Mohammed A. Alshawsh ◽  
Ramzi A. Mothana ◽  
Hassan A. Al-shamahy ◽  
Salah F. Alsllami ◽  
Ulrike Lindequist
Keyword(s):  
Medicinal Plants ◽  
Antimalarial Activity ◽  
Traditional Healers ◽  
Antiplasmodial Activity ◽  
World Health ◽  
Moderate Activity ◽  
Phytochemical Screening ◽  
Cissus Rotundifolia ◽  
Health Organization

Developing countries, where malaria is one of the most prevalent diseases, still rely on traditional medicine as a source for the treatment of this disease. In the present study, six selected plants (Acalypha fruticosa,Azadirachta indica,Cissus rotundifolia,Echium rauwalfii,Dendrosicyos socotranaandBoswellia elongata) commonly used in Yemen by traditional healers for the treatment of malaria as well as other diseases, were collected from different localities of Yemen, dried and extracted with methanol and water successfully. The antiplasmodial activity of the extracts was evaluated against fresh clinical isolates ofPlasmodium falciparum. The selectivity parameters to evaluate the efficacy of these medicinal plants were measured byin vitromicro test (Mark III) according to World Health Organization (WHO) 1996 & WHO 2001 protocols of antimalarial drug tests. Among the investigated 12 extracts, three were found to have significant antiplasmodial activity with IC50values less than 4 µg/ml, namely the water extracts ofA. fruticosa,A. indicaandD. socotrana. Six extracts showed moderate activity with IC50values ranging from 10 to 30 µg/ml and three appeared to be inactive with IC50values more than 30 µg/ml. In addition, preliminary phytochemical screening of the methanolic and aqueous extracts indicated the presence of saponins, tannins, flavonoids, terpenoids, polysaccharides and peptides.

scholarly journals Design and Development of an Instrument on Knowledge of Food Safety, Practices, and Risk Perception Addressed to Children and Adolescents from Low-Income Families

2021 ◽  
Vol 13 (4) ◽  
pp. 2324
Author(s):  
Sueny Andrade Batista ◽  
Elke Stedefeldt ◽  
Eduardo Yoshio Nakano ◽  
Mariana de Oliveira Cortes ◽  
Raquel Braz Assunção Botelho ◽  
...  
Keyword(s):  
Food Safety ◽  
Risk Perception ◽  
Low Income ◽  
Raw Materials ◽  
World Health ◽  
Low Income Students ◽  
Level Of Knowledge ◽  
Low Income Families ◽  
Health Organization ◽  
Rules Set

In the fight against foodborne diseases, expanding access to information for different groups is needed. In this aspect, it is crucial to evaluate the target audience’s particularities. This study constructed and validated an instrument containing three questionnaires to identify the level of knowledge, practices, and risk perception of food safety by low-income students between 11 and 14 years old. The following steps were used: systematic search of the databases; conducting and analyzing focus groups; questionnaires development; and questionnaires analysis. After two judges’ rounds, the final version was reached with 11 knowledge items, 11 practice items, and five risk perception items. The content validation index values were higher than 0.80. The adopted methodology considered the students’ understanding and perceptions, as well the appropriate language to be used. Besides, it allowed the development of questionnaires that directly and straightforwardly covers the rules set by the World Health Organization for foodborne disease control called Five Keys to Safer Food (keep clean; separate raw and cooked; cook thoroughly; keep food at safe temperatures; and use safe water and raw materials). Its use can result in a diagnosis for elaborating educational proposals and other actions against foodborne illness in the most vulnerable population.

Bioactive Natural Medicinal Plants in South Indian Western Ghats and Their Pharmacological Importance

2020 ◽  
Vol 6 (2) ◽  
pp. 62-69
Author(s):  
M. Tamizharasi ◽  
R. Rajila ◽  
D. Beula Shiny ◽  
J. Vijila Jasmin ◽  
T. Kumaran
Keyword(s):  
Medicinal Plants ◽  
Western Ghats ◽  
New Drugs ◽  
World Health ◽  
Plant Resources ◽  
Medical Products ◽  
Primary Health ◽  
South Indian ◽  
The World ◽  
Health Organization

Awareness of traditional knowledge and medicinal plants can play a key role in the utilization and discovery of natural plant resources. Plants became the basis of medicine system throughout the world for thousands of years and continue to provide mankind with new remedies. Researchers generally agree that natural products from plants and other organisms have been the most consistently successful source for ideas for new drugs. The world health organization estimates that 80% of the population living in the developing countries relies exclusively on traditional medicine for their primary health care. More than half of the world's population still relies entirely on plants for medicines, and plants supply the active ingredients of most traditional medical products. The review shows the south Indian medicinal plant products has been used by people to treat various health ailments.

scholarly journals Factors increasing safety of the disabled road users

2018 ◽  
Vol 231 ◽  
pp. 03006
Author(s):  
Monika Ucińska ◽  
Ewa Odachowska
Keyword(s):  
Road Traffic ◽  
Functional Limitations ◽  
Significant Degree ◽  
World Health ◽  
Safe Driving ◽  
The Road ◽  
Road Users ◽  
The World ◽  
The Disabled ◽  
Health Organization

A report by the World Health Organization indicates that over one billion people in the world are affected by some form of disability or have limited fitness, and 200 million have difficulties in functioning [1]. In Poland, according to the statistics, there are 7.5 million people with functional limitations, including almost 2.5 million those in a significant degree [2]. Many people with different dysfunctions drive vehicles, among this group there are also older people, who, with age experience the reduction of many functions affecting the safe driving of the vehicle. To assess some factors increasing the safety of disabled participants in the road traffic, selected psychomotor aspects have been verified. This article presents analyses related to determining the capabilities of people with disabilities depending on whether the disability was congenital or acquired. These drivers were also compared with non-disabled road users. Psychomotor performance was checked using the DTS (Driver Test Station) device. It was noticed that people with acquired disability do better in the majority of tests measuring both pressure forces and reactions of particular limbs in comparison with people with a congenital disability. The research presented sets the direction for further explorations, mainly due to the small group of respondents, but they can nevertheless form the basis for further hypotheses and their verification.

scholarly journals Simple, At-Site Detection of Diethylene Glycol/Ethylene Glycol Contamination of Glycerin and Glycerin-Based Raw Materials by Thin-Layer Chromatography

1998 ◽  
Vol 81 (1) ◽  
pp. 44-50 ◽  
Author(s):  
Allen S Kenyon ◽  
Shi Xiaoye ◽  
Wang Yan ◽  
Ng Wai Har ◽  
Robert Prestridge ◽  
...  
Keyword(s):  
Thin Layer ◽  
Diethylene Glycol ◽  
Visual Inspection ◽  
Raw Materials ◽  
World Health ◽  
Visual Method ◽  
Laboratory Facilities ◽  
Training Samples ◽  
Health Organization ◽  
Layer Chromatography

Abstract This paper describes a rapid, inexpensive thin-layer chromatographic (TLC) method that separates diethylene glycol (DEG) from glycerin and other glycols. Studies with collaborating laboratories of the World Health Organization have shown that about 6% DEG in glycerin and about 2% DEG in acetaminophen (paracetamol) elixirs may be detected by direct visual inspection of the developed TLC sheets. Staining the sheet permits detection of DEG at less than 0.1%. The method costs less than $1.00 per test and takes 20 min by visual inspection, longer when staining is required. The visual method can be performed without laboratory facilities by personnel having little previous training. Samples testing positive by the visual method can be submitted to a laboratory for confirmation and quantitation of DEG.

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