scholarly journals Methods of camouflage vitiligo (literature review)

2021 ◽  
Vol 24 (2) ◽  
pp. 161-166
Author(s):  
Kseniia A. Vovdenko ◽  
Makhabbat Lecaillon ◽  
Konstantin M. Lomonosov
Keyword(s):  
Depressive Disorders ◽  
Alternative Therapy ◽  
Clinical Manifestations ◽  
Psychological Adaptation ◽  
Foreign Markets ◽  
Comprehensive Therapy ◽  
Pubmed Database ◽  
Long Time ◽  
Compliance To Treatment ◽  
Correct Application

Vitiligo significantly affects the quality of life of patients, their social and psychological adaptation in society. It has been noted that patients with vitiligo are more likely to develop anxiety and depressive disorders, suicidal thoughts. Standard therapy regimens today often take a long time, are not enough effective and do not always meet the expectations of the patient and the dermatologist, reduces compliance to treatment. In this regard, comprehensive therapy for vitiligo remains a pressing issue to this day. Medical camouflage is a promising adjunctive or alternative therapy for vitiligo, as it allows to control the clinical manifestations of the disease. The purpose of this review is to consider the main types of medical camouflage in the Russian and foreign markets, their availability and principles of action. The PubMed database and the Internet were used to identify the most effective, affordable, and easy-to-use products available in the Russian and foreign markets. The research identified the most significant products that are most convenient to apply to the skin and are easily available for purchase by vitiligo patients in Russia. Parameters such as shape, texture, composition and effect duration were evaluated. Each group of preparations was described in detail, as well as the technique for their correct application. Thus, this review will be useful to all practicing dermatologists in controlling the clinical course of vitiligo as well as its skin manifestations.

Respiratory tract damage with bocavirus infection in children

2020 ◽  
Vol 19 (2) ◽  
pp. 14-18
Author(s):  
E. V. Sharipova ◽  
I. V. Babachenko ◽  
M. A. Shcherbatyh
Keyword(s):  
Respiratory Tract ◽  
Lower Respiratory Tract ◽  
Clinical Manifestations ◽  
Respiratory Viruses ◽  
Community Acquired Pneumonia ◽  
Human Bocavirus ◽  
Long Time ◽  
Clinically Significant ◽  
Tract Infections ◽  
Tract Damage

Long time the main pathogens associated with the development of community-acquired pneumonia were bacteria. However, in recent years in the Russian Federation, like all over the world, the view of the damage of lower respiratory tract changed, including a unique approach to community-acquired pneumonia as a bacterial infection, and respiratory viruses have become seen as a direct cause of lower respiratory tract damage, or as part of a viral-bacterial co-infection. These studies became possible since the widespread introduction of PCR techniques in the clinical setting, identification of respiratory viruses has increased and new microorganisms such, one as human bocavirus have been discovered. Objective: to study the features of respiratory tract damage in acute bocavirus infection in children of different ages. Materials and methods: A retrospective analysis of 97 medical hospital documentation of children with acute bocavirus infection, detected confirmed by PCR in nasopharyngeal aspirate. Results: In this work, it was shown that human bocavirus spread throughout the year with an increase in the incidence of clinically significant forms in the autumnwinter period, including during the period of an increase in the incidence of influenza. HBoV infection requiring hospitals is most significant in the first three years of life. In 74.2% of hospitalized children, bocavirus infection occurs with lower respiratory tract infections in the form of bronchitis — 77.8%, pneumonia — 28.9% and rarely bronchiolitis and is complicated by the development of respiratory failure in 28.9% of cases. Changes in the blood test are non-specific, and the level of C-reactive protein in children with various clinical manifestations of HBoV infection generally does not exceed 50 mg / l. An x-ray of the chest organs does not objectively reflect the existing volume and nature of the inflammatory process in the lungs.

scholarly journals A systematic review of historical and current trends in Chagas disease

2021 ◽  
Vol 8 ◽  
pp. 204993612110337
Author(s):  
Diego-Abelardo Álvarez-Hernández ◽  
Rodolfo García-Rodríguez-Arana ◽  
Alejandro Ortiz-Hernández ◽  
Mariana Álvarez-Sánchez ◽  
Meng Wu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chagas Disease ◽  
Case Reports ◽  
Clinical Manifestations ◽  
Human Case ◽  
Acute Stage ◽  
Diagnostic Tools ◽  
Chronic Stage ◽  
Pubmed Database ◽  
Trypanocidal Drugs

Introduction: Chagas disease (CD) is caused by Trypanosoma cruzi. When acquired, the disease develops in stages. For diagnosis, laboratory confirmation is required, and an extensive assessment of the patient’s health should be performed. Treatment consists of the administration of trypanocidal drugs, which may cause severe adverse effects. The objective of our systematic review was to analyze data contained in the CD published case reports to understand the challenges that patients and clinicians face worldwide. Materials and methods: We performed a systematic review following the PRISMA guidance. PubMed database was explored using the terms ‘American trypanosomiasis’ or ‘Chagas disease’. Results were limited to human case reports written in English or Spanish. A total of 258 reports (322 patients) were included in the analysis. Metadata was obtained from each article. Following this, it was analyzed to obtain descriptive measures. Results: From the sample, 56.2% were males and 43.8% were females. Most cases were from endemic countries (85.4%). The most common clinical manifestations were fever during the acute stage (70.0%), dyspnea during the chronic stage in its cardiac form (53.7%), and constipation during the chronic stage in its digestive form (73.7%). Most patients were diagnosed in the chronic stage (72.0%). Treatment was administered in 56.2% of cases. The mortality rate for the acute stage cases was 24.4%, while for the chronic stage this was 28.4%. Discussion: CD is a parasitic disease endemic to Latin America, with increasing importance due to human and vector migration. In this review, we report reasons for delays in diagnosis and treatment, and trends in medical practices. Community awareness must be increased to improve CD’s diagnoses; health professionals should be appropriately trained to detect and treat infected individuals. Furthermore, public health policies are needed to increase the availability of screening and diagnostic tools, trypanocidal drugs, and, eventually, vaccines.

scholarly journals A solitary giant neurofibroma of inguinal region: A case report

2021 ◽  
Vol 104 (1) ◽  
pp. 003685042110042
Author(s):  
Haiying Zhou ◽  
Hui Lu
Keyword(s):  
Tumor Resection ◽  
Clinical Manifestations ◽  
Inguinal Region ◽  
Nerve Sheath Tumor ◽  
Neurogenic Tumors ◽  
Long Time ◽  
Giant Neurofibroma ◽  
History Of ◽  
Neuroectodermal Origin ◽  
Recurrence Tendency

Neurofibroma is a rare nerve sheath tumor of neuroectodermal origin, especially the huge and isolated neurofibroma located in the inguinal region. To our knowledge, no such case has previously been reported. We report a case of 34-year-old male patient with a 4-year history of progressive enlargement of the medial root mass in his left thigh with sitting and standing disorders along with pain. The tumor was completely removed by operation, and pathological diagnosis showed neurofibroma. There was no obvious neurologic defect after surgery, and no recurrence tendency was found in the follow-up of 2 years. For a large solitary mass with slow growth and no malignant clinical manifestations for a long time, clinicians cannot rule out the hypothetical diagnosis of neurofibroma, even though its growth site is very rare, such as this case of a huge tumor located in the groin. For neurogenic tumors, early operation should be performed, and the prognosis of patients after tumor resection is excellent.

CHRONIC ATYPICAL NEUTROPHILIC DERMATOSIS WITH LIPODYSTROPHY AND FEVER (CANDLE SYNDROME) IN PEDIATRIC PRACTICE

2021 ◽  
Vol 100 (2) ◽  
pp. 254-261
Author(s):  
O.G. Sukhovjova ◽  
◽  
I.A. Ivanova ◽  
N.A. Kalugina ◽  
E.S. Zholobova ◽  
...  
Keyword(s):  
Clinical Observation ◽  
Clinical Manifestations ◽  
Maculopapular Rash ◽  
The Body ◽  
Neutrophilic Dermatosis ◽  
Inherited Disease ◽  
Laboratory Activity ◽  
Ubiquitinated Proteins ◽  
Systemic Inflammatory Reaction ◽  
Long Time

The purpose of this publication is to describe the CANDLE syndrome (its etiology, pathogenesis, clinical manifestations) and present a clinical observation. CANDLE syndrome is a rare genetically inherited disease caused by impaired assembly by of the protease, which leads to the accumulation of abnormal (ubiquitinated) proteins in B-lymphocytes, fibroblasts, macrophages and some other cells of the body. As a result, an excessive activation of interferon synthesis occurs and a systemic inflammatory reaction develops with symptoms such as febrile fever, skin syndrome, represented by nodules and maculopapular rash, hepatosplenomegaly, lipodystrophy, amyotrophy, delayed physical development, as well as high laboratory activity. The article describes a clinical observation of a female patient with typical symptoms of CANDLE syndrome. However, due to the rarity of the disease and lack of publications describing it, it has not been possible to diagnose the child for a long time.

scholarly journals Movement Disorders Related to Gluten Sensitivity: A Systematic Review

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1034 ◽  
Author(s):  
Ana Vinagre-Aragón ◽  
Panagiotis Zis ◽  
Richard Grunewald ◽  
Marios Hadjivassiliou
Keyword(s):  
Movement Disorders ◽  
Medical Literature ◽  
Wide Spectrum ◽  
Clinical Manifestations ◽  
Gluten Sensitivity ◽  
Gluten Free ◽  
Inclusion Criteria ◽  
Pubmed Database ◽  
Gluten Sensitive Enteropathy ◽  
The Subject

Gluten related disorders (GRD) represent a wide spectrum of clinical manifestations that are triggered by the ingestion of gluten. Coeliac disease (CD) or gluten sensitive enteropathy is the most widely recognised, but extra-intestinal manifestations have also been increasingly identified and reported. Such manifestations may exist in the absence of enteropathy. Gluten sensitivity (GS) is another term that has been used to include all GRD, including those where there is serological positivity for GS related antibodies in the absence of an enteropathy. Gluten ataxia (GA) is the commonest extraintestinal neurological manifestation and it has been the subject of many publications. Other movement disorders (MDs) have also been reported in the context of GS. The aim of this review was to assess the current available medical literature concerning MDs and GS with and without enteropathy. A systematic search was performed while using PubMed database. A total of 48 articles met the inclusion criteria and were included in the present review. This review highlights that the phenomenology of gluten related MDs is broader than GA and demonstrates that gluten-free diet (GFD) is beneficial in a great percentage of such cases.

Interkulturelle Aspekte bei der Gestaltung von Unternehmenswebseiten

2014 ◽  
Vol 55 (2) ◽  
pp. 15-22
Author(s):  
Ulrike Reisach
Keyword(s):  
International Management ◽  
Corporate Communications ◽  
Foreign Markets ◽  
Target Groups ◽  
The World ◽  
Long Time ◽  
Technical Features ◽  
Selection Of ◽  
International Companies

Unternehmen präsentieren sich nicht nur im eigenen Land, sondern auf allen Zielmärkten mit ihrer Webseite. Diese dient als elektronische „Visitenkarte“, als Erstinformation über das Unternehmen, seine Produkte, Menschen und Standorte. Viele Firmen, die ihre Webseiten internationalisieren, denken dabei zunächst an eine Übersetzung aller Inhalte. Viel wichtiger ist es jedoch, Inhalte und Gestaltung der Webseiten an die lokalen Wahrnehmungsmuster, Stile und Nutzungsgewohnheiten anzupassen. Companies are increasingly using international webpages as a tool to communicate with their local target groups. Quite often they seem to assume that internationalization just means translating the existing content – but in reality it means much more: A deliberate selection of contents, design and structure, including key messages, pictures and videos, fonts and style as well as technical features, SEO and interactivity are crucial for a successful online appearance in foreign markets. Using practical examples from all over the world, Ulrike Reisach, Professor for International Management and Corporate Communications, and long-time director for leading international companies, explains what has to be considered in order to get your company’s international webpage right. Keywords: website struktur, suchmaschine, schönheitsideale, meta tags, luxus, hardware, fonts

scholarly journals Neglected intrauterine fetal demise for more than two decades leading to the development of a lithopedion: a case report

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Fitsum Fikru Gebresenbet ◽  
Abdu Mengesha Mulat ◽  
Namus Muhajir Nur ◽  
Ferehiwot Bekele Getaneh
Keyword(s):  
Vesicovaginal Fistula ◽  
Rare Complication ◽  
Clinical Manifestations ◽  
Clinical History ◽  
The Body ◽  
Obstructed Labor ◽  
Fetal Demise ◽  
Case Presentation ◽  
Intrauterine Fetal Demise ◽  
Long Time

Abstract Background Lithopedion is a word derived from the Greek words lithos, meaning stone, and paidion, meaning child, to describe a fetus that has become stony or petrified. Lithopedion is a rare complication of pregnancy which occurs when a fetus dies and becomes too large to be reabsorbed by the body. This entity in rare circumstances can be challenging for physicians to diagnose since it has a range of clinical manifestations. Case presentation We present a case of a 55-year-old, gravida IV para III, Ethiopian woman from Ethiopia with a retained fetus and vesicovaginal fistula after an obstructed labor and a neglected intrauterine fetal demise of approximately 22 years. The diagnosis was confirmed by suggestive clinical history, physical examination findings, and an abdominopelvic computed tomography scan. Laparotomy and removal of the lithopedion was done and our patient was sent to a fistula hospital for vesicovaginal fistula repair. Conclusion This case is a rare phenomenon in which the dead fetus remained in the uterus for a long time after a neglected obstructed labor and uterine rupture.

scholarly journals Biological mechanism study of meditation and its application in mental disorders

2020 ◽  
Vol 33 (4) ◽  
pp. e100214
Author(s):  
Hui Shen ◽  
Meijuan Chen ◽  
Donghong Cui
Keyword(s):  
Mental Disorders ◽  
Depressive Disorders ◽  
Clinical Medicine ◽  
Alternative Therapy ◽  
Mechanism Study ◽  
Addictive Disorders ◽  
Brain Structure And Function ◽  
Major Depressive Disorders ◽  
And Function ◽  
Telomere Regulation

In recent years, research on meditation as an important alternative therapy has developed rapidly and been widely applied in clinical medicine. Mechanism studies of meditation have also developed progressively, showing that meditation has great impact on brain structure and function, and epigenetic and telomere regulation. In line with this, the application of meditation has gradually been expanded to mental illness, most often applied for major depressive disorders and substance-related and addictive disorders. The focus of this paper is to illustrate the biological mechanisms of meditation and its application in mental disorders.

Recombinant interferons in comprehensive therapy for new coronavirus infection

2020 ◽  
Vol 18 (3) ◽  
pp. 41-46
Author(s):  
E.V. Melekhina ◽  
◽  
S.V. Nikolaeva ◽  
A.S. Ilyinskaya ◽  
Zh.B. Ponezheva ◽  
...  
Keyword(s):  
Early Treatment ◽  
Epstein Barr Virus ◽  
Companion Animals ◽  
Clinical Manifestations ◽  
Upper Respiratory Tract ◽  
Recombinant Interferon ◽  
Barr Virus ◽  
Comprehensive Therapy ◽  
Coronavirus Infection ◽  
Epstein Barr

The second decade of the 21st century has brought us a new coronavirus infection, SARS-CoV-2, which affects not only animals (livestock, companion animals, birds), but also people, causing severe disease in them (COVID-19) with various clinical variants: from upper respiratory tract lesions to sepsis and thromboembolism. Coronaviruses are known to suppress the production of IFN-I. Therefore, administration of IFN-I is a promising strategy for early treatment and prevention of COVID-19. In the Russian Federation, treatment of COVID-19 in children is performed in accordance with the recommendations of the Ministry of Health of Russia and depends on the clinical form of the disease. Mild and moderate forms of the disease, observed in the majority of children, are treated according to the protocols for managing ARVI, bronchitis, bronchiolitis, and pneumonia in children. However, the fact that non-severe COVID-19 shares clinical manifestations with other infections caused by respiratory viruses and herpesviruses (including cytomegalovirus, HHV6A/B, and Epstein-Barr virus), as well as recently increased proportion of mixed viral infections necessitate (until the etiological diagnosis is confirmed) the administration of drugs recommended for the treatment of seasonal ARVI (including intranasal forms of IFN-α, etc.). Such therapeutic tactics often ensures faster improvement and symptom elimination. We report a case of mixed respiratory infection caused by two viruses (SARS-CoV-2 and Epstein–Barr virus) in a child. Early treatment with recombinant interferon-α2b with taurine resulted in fever alleviation and normalization of child’s condition by the moment of transfer to a specialized department. Key words: SARS-CoV-2, COVID-19, children, treatment, interferon.

Cross-Cultural Challenges in the Diagnosis of Depression

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
M. Schouler-Ocak ◽  
M. Aichberger ◽  
M. Rapp ◽  
A. Heinz
Keyword(s):  
Depressive Disorders ◽  
Cross Cultural ◽  
Behavioural Disorders ◽  
Cultural Challenges ◽  
Cultural Aspects ◽  
The World Bank ◽  
Treatment Of Depression ◽  
Psychic Disorders ◽  
Long Time ◽  
Treatment Facilities

For a long time it was assumed that depressive disorders were a classic western problem specific to industrial states. However, the World Bank discovered in a study as early as 1993 that depression in Third World countries was already fifth on the list of illnesses which comprise the largest contribution to the Global Burden of Disease. Affective and behavioural disorders as well as somatic complaints represent the three central categories of symptoms in depression. In western cultures an affective disorder is seen as the main characteristic of a depression, whereas in other cultures different symptoms can be in the foreground. The increase in supraregional communication and cooperation as well as the worldwide increase in immigrant populations demand that cultural aspects are considered in the diagnosis and treatment of depression. Physicians need to consider the cultural background of their patients in order to achieve an optimal therapy. If the sociocultural aspects, which cannot always be fully appreciated, of a culturally sensitive diagnosis are not taken into consideration, this can lead to an artificial prevalence of the disorder by making false diagnoses. In order to minimize these mistakes, the guideline for judging cultural influencing factors should be used to complete the diagnosis.Not only the development of culturally adequate therapy concepts and institutions, but also the expansion of knowledge about the psychopathology and epidemiolgy of psychic disorders, e. g. of depression in immigrant groups and the examination of their use of treatment facilities, are the goals of cross-cultural psychiatry and psychotherapy.

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