Summary of the current state of the pathogenesis of glaucoma

1927 ◽  
Vol 23 (8) ◽  
pp. 839-845
Author(s):  
V. P. Roshchin

The problem of glaucoma has, for many reasons, occupied and continues to occupy a prominent place in the ophthalmic press. It is enough to recall that 19% of all blind people owe their misfortune to glaucoma to understand why interest in this affliction has never faded among ophthalmologists. Furthermore, no ophthalmologist is quite sure that a certain method of treatment, even if the patient has timely applied for medical attention, can definitely prevent a sad outcome in every single case. This plus the absence of a unified and correct view of the essence of glaucoma keeps ophthalmologists in a constant state of flux, constantly striving to uncover the hidden springs of the disease process on the one hand, and to find a more radical means to combat it on the other.

1887 ◽  
Vol 33 (142) ◽  
pp. 230-238 ◽  
Author(s):  
C. Heimann

Certain therapeutic effects upon the human organism ascribed to cocaine,∗ occasioned me to make use of the drug in suitable cases of psychosis and psycho-neurosis. Stimulant action and exhilaration (Euphoria) on the one hand, and on the other depression of undue sensitiveness, these were the effects I looked for from the alkaloid. Unfortunately, I am able to record scarcely a single case of certain and permanent cure following the use of the drug.


Axon ◽  
2019 ◽  
Author(s):  
Peter Funke

In the first part of my ‘workshop report’, I will provide information about the current state of the epigraphical editions of the Inscriptiones Graecae. Subsequently, I will focus on the plans for the upcoming years. In this context, questions pertaining to epigraphic research in new geographic regions, on the one hand, and the revision of past editions, on the other hand, are paramount. In the second part of my report, I will outline the current state and future perspectives of the digitisation of the IG.


Axon ◽  
2019 ◽  
Author(s):  
Sophia Aneziri ◽  
Denis Rousset

The present paper presents the first volume of Collezioni epigrafiche della Grecia occidentale/Epigraphische Sammlungen aus Westgriechenland. It reflects, on the one hand, on the absolute necessity to preserve multilingualism in Altertumswissenschaft; on the other, on the purposes and methods of making catalogues or inventories of epigraphic collections; and finally on the past conditions and the current state of epigraphic and prosopographic research in West Greece and especially in Aetolia.


Author(s):  
Elizabeth Fife ◽  
Laura Hosman

This paper analyses the recent phenomenon of private/public partnerships (PPPs) in the ICT sector of the developing world. The partners may come to these projects with divergent motivations: profit on the one hand and the provision of public services on the other, but at the end of the day, the interests of the partners that are symbiotic can – and indeed should – be aligned to ensure successful long-term projects. To investigate what can be done to promote successful and sustainable PPPs, this paper extends the traditional two-actor analysis to include both a third-party non-profit-oriented facilitating organization and the technology recipients that are the targets of these projects. Following an overview of the current state of PPPs in the developing world, the paper provides two case studies, based in Vietnam, where all four of the above-mentioned stakeholders were involved. The cases reveal important success factors that can be applied to future PPPs in the ICT sector.


Author(s):  
Olexandr Yemelyanov ◽  
◽  
Tetyana Petrushka ◽  
Anatolii Havryliak ◽  
Ostap Ivanchyna ◽  
...  

The efficiency of economic activity of enterprises largely depends on the proper management of their assets. Whereas, an important type of assets of enterprises is its operating wealth, which serves the processes of production and marketing of products of economic entities. This is a complex process of circulation of operating assets, during which transformation from one species to another is being carried out. The course of such a process may involve different amounts of demand for current assets for a certain volume of production and sales. In other words, these assets are characterized by a certain level of flexibility and the main task of managing them is to establish their rational value. This value should ensure, on the one hand, the continuity of the production process at the enterprise and the timeliness of receipt of funds from the sale of products, and, on the other hand, the absence of excess inventories and other types of operating assets. The solution of this problem requires the introduction of an effective mechanism for managing its current assets. Considering this, the purpose of this article is to develop theoretical principles for managing operating assets of enterprises. It has been shown that the process of such management should be based on the system, created at the enterprises of information support of this process. Under this system is proposed to understand a set of information arrays and formalized algorithms for its processing, with which it is possible to assess the current state of use of operating assets of the company and develop a set of measures aimed at structuring and optimizing its volume. The basic requirements to designing of system of information maintenance of management of operating assets of the enterprises have been presented. The required information for the management of operating assets has been grouped. The areas grouping of operating assets management of the enterprise depending on the stages of its circulation has been carried out. The model of management of debts receivable of the enterprises has been specified. The use of the developed theoretical principles of operating assets management of enterprises in the practice of their activities increases financial results by streamlining the volume and structure of current assets of economic entities.


Author(s):  
Tatiana Prorokova

This chapter scrutinizes the complex relationship between climate change and theology, as represented in First Reformed, as well as Paul Schrader’s understanding of humanity’s major problems today. Analyzing the issue of ecological decline through the prism of religion, Schrader outlines the ideology that presumably might help humanity survive at the age of global warming. Through the complex discussions of such issues as despair, anxiety, and hope, Schrader deduces the formula of survival in which preservation is the key component. Equating humans to God, Schrader, on the one hand, censures those actions that led to progress but destroyed the environment, yet, on the other hand, he foregrounds the fact that humans can also save the planet now. Schrader portrays both humans and Earth as living organisms created by God. He draws explicit parallels between the current state of our planet and the problems that we experience – from political ones, including war, to more personal ones like health issues.


2020 ◽  
Vol 42 (2) ◽  
pp. 177-198
Author(s):  
Yann Giraud

Historians of economics rarely consider textbooks as more than passive receptacles of previously validated knowledge. Therefore, their active role in shaping the discipline and its image is seldom addressed. In this paper, I study the making of Paul Samuelson’s successive editions of Economics from 1967 to 1973 as an instance of how textbooks stand at the crossroads between disciplinary knowledge, pedagogy, and larger political and societal concerns. In the mid-1960s, Economics, now at its sixth edition, was at the height of its success. Considered one cornerstone of modern economics, it was also at the center of a number of criticisms dealing with the current state of the economic discipline and its teaching in the universities. While the profession expressed its concern over the lack of relevance of economics to address the pressing issues of the day and pleaded for a new “problem-solving” approach to economic education, the late 1960s witnessed the emergence of a new generation of “radical” economists criticizing the economics orthodoxy. Their contention that mainstream theory had neglected the issues of class struggle and capitalist exploitation found a favorable echo among an increasingly politicized population. Using archival materials, I show how Samuelson, helped by his editorial team at McGraw-Hill, attempted to take into account these changes in order to ensure the continuing success of subsequent editions of his text in an increasingly competitive market. This study emphasizes Samuelson’s ambiguous attitude toward his contenders, revealing, on the one hand, his apparent openness to discussion and outsiders’ suggestions, and, on the other hand, his firm attachment to mildly liberal politics and aversion to Marxism, unchanged through revisions. It also helps refine a notion that is often invoked but never fully expounded in textbook studies: that of the audience.


2020 ◽  
Vol 34 (05) ◽  
pp. 9354-9361
Author(s):  
Kun Xu ◽  
Linfeng Song ◽  
Yansong Feng ◽  
Yan Song ◽  
Dong Yu

Existing entity alignment methods mainly vary on the choices of encoding the knowledge graph, but they typically use the same decoding method, which independently chooses the local optimal match for each source entity. This decoding method may not only cause the “many-to-one” problem but also neglect the coordinated nature of this task, that is, each alignment decision may highly correlate to the other decisions. In this paper, we introduce two coordinated reasoning methods, i.e., the Easy-to-Hard decoding strategy and joint entity alignment algorithm. Specifically, the Easy-to-Hard strategy first retrieves the model-confident alignments from the predicted results and then incorporates them as additional knowledge to resolve the remaining model-uncertain alignments. To achieve this, we further propose an enhanced alignment model that is built on the current state-of-the-art baseline. In addition, to address the many-to-one problem, we propose to jointly predict entity alignments so that the one-to-one constraint can be naturally incorporated into the alignment prediction. Experimental results show that our model achieves the state-of-the-art performance and our reasoning methods can also significantly improve existing baselines.


Author(s):  
Göran Roos

This chapter explores the current state of flux in manufacturing. It examines the forces that drive fragmentation and dispersion of value chains on the one hand and those that drive concentration and integration of value chains on the other. These forces are underpinned by changes in technology, wage costs, business environment, importance of economies of scale for production, need for interaction with customers and input providers, needs for skills in the manufacturing workforce, and the workings of industrial commons and economic complexity. Analysing these changes at the level of the firm, this chapter puts the competitive focus on the creation of value more than on cutting costs (although both are important). The policy environment must provide both carrot and stick to ensure that firms align with these developments. In this dynamic world, an effective policy response requires a shift from any single dominating economic lens (e.g. neo-classical, neo-Keynesian, neo-Schumpeterian, evolutionary) to a situation-specific approach.


Author(s):  
Thomas Hellman Morton

In an ode addressed to his friend Fabullus, the Roman poet Catullus speaks of a fragrance so pleasing that “when you smell it you will beg the gods to make you all nose.” Would that the recipe for such a scent had been transmitted through the ages! Even today, however, it is not possible to document chemical composition with adequate fidelity to reconstruct an odor perfectly. Catullus writes that the gods of love gave the perfume to his girlfriend. Suppose such gods existed and could list the ingredients of its aroma. The list would contain hundreds—perhaps thousands—of chemical structures and their relative proportions. Very likely, many of the structures would stand for compounds that are currently unknown, but they could be synthesized in the laboratory. Would that knowledge permit me to reproduce the odor? This chapter argues that the answer remains uncertain. The current state of chemical knowledge can neither account for why an odor smells the way it does nor what determines its intensity. The recipe for replicating a sensory experience—what is essential and what is superfluous—remains obscure. The sense of smell challenges chemical understanding. On the one hand, given the structure of a new molecule a chemist can predict its spectroscopic properties over a wide domain of electromagnetic frequencies. A mixture ordinarily displays a spectrum that superimposes the spectra of its individual components, unless they physically interact with each other. In the chemical senses, on the other hand, perceptions of mixtures often cannot be inferred from their constituents, even though the components do not interact at the molecular level. Moreover, no one can reliably predict the organoleptic properties (taste or smell) of a new molecule from its structure. Even if that were possible, the English language does not offer a vocabulary with which to describe new smells, except by analogy to odors that are already familiar. The poverty of descriptors means that, in talking about olfactory stimuli, many people allude to direct experiences. These allusions call on memories of characteristic odors of familiar objects, which represent “unitary percepts.”


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