scholarly journals Some approaches to dispanserization of patients with hypertensive disease at territorial internist's area

2019 ◽  
Vol 100 (6) ◽  
pp. 905-909
Author(s):  
I E Babushkin ◽  
O V Gataulina ◽  
E I Demina ◽  
D S Bublikov ◽  
N V Duruda ◽  
...  

Aim. To study creatinine clearance, body mass index and to perform ROSE survey amomg patients with hypertension of different age groups at territorial internist's area. Methods. The study involved 112 patients aged 40 to 75 years. Patients were divided into two groups according to the age: group 1 40 to 61 years, 55 people (15 men and 40 women), the average age 52.67.1 years; group 2 62 to 75 years, 57 people (15 men and 42 women), the average age 69.84.4 years. Creatinine clearance and body mass index were measured, and ROSE survey was conducted. Results. In group 1 creatinine clearance 60 ml/min was in 5 (9%) subjects, in group 2 in 20 (35%; p=0.002). In group 1 15 (27%) subjects had normal body mass, in group 2 5 (9%). In group 1 overweight was registered in 18 (33%) subjects, and in group 2 in 24 (42%; p=0.407). Class I obesity in group 1 was found in 15 (27%) patients, in group 2 in 16 (28%; p=0.907). Class II obesity in group 1 was noted in 5 (9%) patients, in group 2 in 4 (7%; p=0.955). Class III obesity in group 1 was registered in 2 (4%) people and in 8 (14%) in group 2 (p=0.110). According to the results of ROSE questionnaire, signs of angina pectoris were found in 7 (13%) patients in group 1 and 17 (30%) in group 2 (p=0.048). Conclusion. In the territorial internist's area the proportion of cases of overweight and obesity among patients of groups 1 and 2 with hypertension did not differ significantly (p 0.05); in patients from group 2 with hypertension creatinine clearance less than 60 ml/min was identified 3.9 times more often than in the younger age group (p=0.002); in patients of group 2 with hypertension were 2.3 times more likely to have angina, according to ROSE questionnaire than in group 1 (p=0.048).

Children ◽  
2022 ◽  
Vol 9 (1) ◽  
pp. 110
Author(s):  
Sun-Jin Lee ◽  
Sun-Young Kim ◽  
Minsun Kim

Gonadotropin-releasing hormone agonist (GnRHa) therapy is used to control puberty progression and it preserves height potential in patients with idiopathic central precocious puberty (ICPP). This study evaluated the correlation between weight and height gain at menarche following GnRHa treatment among girls with ICPP and relatively central early puberty (EP). We investigated height/weight trends and changes in height from diagnosis to menarche in girls with ICPP and EP treated with GnRHa. The mean difference in height (Δheight) from treatment cessation to menarche was 9.79 ± 3.53 cm. Girls were divided into girls with Δheight ≥ 9.79 cm (Group 1) and girls with Δheight < 9.79 cm (Group 2). Although near adult height was significantly higher in Group 1, the mean body mass index (BMI) and weight were significantly lower at diagnosis, treatment discontinuation, and menarche. The BMI and weight at the three time points were negatively correlated with height. Girls with higher BMI at all three time points had slower growth rates during the study period. Considering that BMI and body weight were closely related to Δheight, proper management of BMI and body weight of girls receiving early puberty treatment might contribute to growth during and after GnRHa treatment.


2020 ◽  
Vol 8 (6) ◽  
pp. 232596712092793
Author(s):  
Christopher Antonacci ◽  
Thomas R. Atlee ◽  
Peter N. Chalmers ◽  
Christopher Hadley ◽  
Meghan E. Bishop ◽  
...  

Background: Pitching velocity is one of the most important metrics used to evaluate a baseball pitcher’s effectiveness. The relationship between age and pitching velocity after a lighter ball baseball training program has not been determined. Purpose/Hypothesis: The purpose of this study was to examine the relationship between age and pitching velocity after a lighter ball baseball training program. We hypothesized that pitching velocity would significantly increase in all adolescent age groups after a lighter baseball training program, without a significant difference in magnitude of increase based on age. Study Design: Cohort study; Level of evidence, 2. Methods: Baseball pitchers aged 10 to 17 years who completed a 15-week training program focused on pitching mechanics and velocity improvement were included in this study. Pitchers were split into 3 groups based on age (group 1, 10-12 years; group 2, 13-14 years; group 3, 15-17 years), and each group trained independently. Pitch velocity was assessed at 4 time points (sessions 3, 10, 17, and 25). Mean, maximum, and mean change in pitch velocity between sessions were compared by age group. Results: A total of 32 male baseball pitchers were included in the analysis. Mean/maximum velocity increased in all 3 age groups: 3.4/4.8 mph in group 1, 5.3/5.5 mph in group 2, and 5.3/5.2 mph in group 3. While mean percentage change in pitch velocity increased in all 3 age groups (group 1, 6.5%; group 2, 8.3%; group 3, 7.6%), the magnitude of change was not significantly different among age groups. Program session number had a significant effect on mean and maximum velocity, with higher mean and maximum velocity seen at later sessions in the training program ( P = .018). There was no interaction between age and program session within either mean or maximum velocity ( P = .316 and .572, respectively). Conclusion: Age had no significant effect on the magnitude of increase in maximum or mean baseball pitch velocity during a velocity and mechanics training program in adolescent males.


Cardiology ◽  
2017 ◽  
Vol 137 (3) ◽  
pp. 159-166 ◽  
Author(s):  
Zubair Shah ◽  
Mark Wiley ◽  
Arun Mahankali Sridhar ◽  
Reza Masoomi ◽  
Mazda Biria ◽  
...  

Objective: The aim of this paper was to study the association between body mass index (BMI) and coronary sinus (CS) brain natriuretic peptide (BNP) levels in patients with heart failure and reduced systolic function (HFrEF). Background: There is an inverse relationship between systemic venous BNP (V-BNP) levels and BMI in patients with HFrEF. It is unclear whether this finding is due to decreased production or due to an increased metabolism of BNP. Since CS-BNP levels reflect BNP production, we hypothesized that assessing the correlation of CS-BNP levels with BMI would provide insight into the mechanism of this inverse relationship of V-BNP and BMI. Methods: We prospectively enrolled 54 subjects with HFrEF who were to undergo cardiac resynchronization device implantation. CS-BNP, V-BNP, and arterial BNP (A-BNP) levels were measured during the implant procedure. Subjects were divided into 2 groups based on their BMI (group 1: BMI <30 and group 2: BMI ≥30). Results: The mean age of the overall study group was 64 ± 10 years. Average BMI for group 1 was 25.8 ± 2.8 and 36.8 ± 4.6 for group 2 (p < 0.03). A history of hypertension was present in 55% (n = 26) of the subjects, while diabetes was reported in 31% (n = 15). Serum creatinine was 1.0 ± 0.2 mg/dL and TSH 2.1 ± 1.4 mIU/L. 79% of the subjects were receiving β-blockers, while 94% were receiving angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. The mean CS-BNP, V-BNP, and A-BNP levels in group 2 were significantly lower than in group 1 (286.2 ± 170.5 vs. 417.5 ± 247.5 pg/mL, p = 0.04; 126.6 ± 32.5 vs. 228 ± 96.4 pg/mL, p = 0.01; and 151.9 ± 28.6 vs. 242 ± 88.8 pg/mL, p = 0.04, respectively). Univariate analysis and multivariate regression adjusted for age, diabetes mellitus, sex, glomerular filtration rate, and left atrial size confirmed BMI as an independent predictor of CS-BNP levels (β = -0.372, p = 0. 03) in our study. Conclusions: In this study, we demonstrate an inverse relationship between CS-BNP levels and BMI in patients with HFrEF. These findings suggest that the previously established inverse relationship between V-BNP and BMI is due to a decreased cardiac production of BNP in obese patients rather than from increased peripheral metabolism.


2017 ◽  
Vol 56 (207) ◽  
pp. 352-356 ◽  
Author(s):  
Saraswati M Padhye

Introduction: High Body Mass Index is one of the risk factors for many chronic diseases and adverse health outcomes. It is associated with an increased risk of coronary heart disease, ischemic stroke, high blood pressure and type 2 diabetes mellitus. It also have many adverse effect on reproductive health of the women like sub fertility, polycystic ovarian disease, menstrual abnormality etc. The purpose of this study is to find Basal Metabolic Rate and the diseases pattern of reproductive age woman in Nepal. Methods: This is a descriptive study of women of reproductive age (15 to 49 years) attending a private gynaecology clinic in Kathmandu Valley from October 2016 to June 2017. Six hundred and eight women of current reproductive age group participated in this study. Women’s particulars and complaints were noted down. Detailed history was taken. Height, weight and blood pressure were recorded and general examination was done. BMI was calculated as BMI is weight in kilogram divided by height in meter square, and it was interpreted as per WHO guidelines. Results: Out of the total 608 participants, 243 (40%) were overweight, 96 (15.8%) were obese. Regarding the common health problems, 154 (25.3%) have sub fertility and 199 (32%) had genitourinary infection. Similarly, 90 (14.8%) had menstrual problems. Conclusions: Prevalence of overweight and obesity has risen significantly comparing to the study done decade ago in same setting. Similarly, sub fertility rate has also risen whereas the prevalence of genitourinary infections has decreased. Keywords: BMI; genitourinary infection; Nepal-reproductive age women; sub fertility.


2011 ◽  
Vol 10 (4) ◽  
pp. 284-288 ◽  
Author(s):  
José Ribas Milanez de Campos ◽  
Nelson Wolosker ◽  
Marco Antonio Soares Munia ◽  
Guilherme Yazbek ◽  
Paulo Kauffman ◽  
...  

OBJECTIVE: Video-assisted thoracic sympathectomy is currently the procedure of choice for the definitive treatment of primary hyperhidrosis, because it is an effective, safe, and minimally invasive method. In the search for better quality of life indexes, all researchers look for predictive factors indicating better surgical outcomes. Failure in the primary treatment, postoperative compensatory hyperhidrosis, body mass index over 25, level of resection of the sympathetic chain, and extent of resection are some of the factors that may negatively influence the results. The objective of this study was to compare, according to the age group, the quality of life after bilateral thoracic sympathectomy for treatment of primary hyperhidrosis in a cohort of 1,644 patients. METHODS: From February 2000 to October 2008, data were collected from 1,644 patients with palmar (71%) or axillary (29%) hyperhidrosis who underwent video-assisted thoracic sympathectomy. The patients were divided into three groups according to their ages. The first group consisted of patients up to 17 years-old, the second from 18 to 30 years-old, and the third of over 30 years-old. All patients had a body mass index of less than 25. RESULTS: In the evaluation 30 days after surgery, improvement of the quality of life in the three groups was observed. There was no significant difference between the age groups. In the present study, 91.9% of the patients presented compensatory hyperhidrosis, with no difference between the age groups. CONCLUSIONS: Patients with primary hyperhidrosis experience quality of life improvement after thoracic sympathectomy regardless of their age.


2020 ◽  
Vol 11 (1) ◽  
pp. 913-920
Author(s):  
Sabir Ali Shaikh ◽  
Rajagopalan Vijayaraghavan ◽  
Das Subir Kumar ◽  
Pal Manidip

Objective of the study was to compare serum level of nitric oxide (NO), endothelial nitric oxide synthase (eNOS), asymmetric dimethylarginine (ADMA), arginine, placental growth factor (PIGF), soluble Fms like tyrosine kinase-1 (sFlt-1), soluble endoglin (sEng), malondialdehyde (MDA), glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase, in normotensive and preeclamptic pregnancies in relation to body mass index (BMI). The study was done on 100 healthy normotensive and 100 preeclamptic pregnant women. Based on BMI, they were categorized into three groups. Group 1 (<25 kg/m2), group 2 (25 – 30 kg/m2) and group 3 (>30 kg/m2).  ADMA, eNOS, arginine, PlGF, sFlt-1, sEng were estimated by ELISA method, and MDA, NO, GPx, SOD, and catalase by spectrophotometric method. Statistically, a significant difference was not observed within normotensive and preeclampsia in relation to BMI. But when respective normotensive was compared with preeclampsia, there was a high increase of ADMA, sFlt-1, sEng, and MDA. A significant decrease was observed in arginine, eNOS, NO, GPx, SOD, and catalase in preeclampsia. This study shows that though preeclampsia is associated with overweight and obesity, but during pregnancy, higher BMI has no additional deleterious effect in preeclampsia.


Author(s):  
Hananjassim Hammod ◽  
Thanaa Abdulmahdi Mokif ◽  
Hussein Jasim Al-harbi

Objective: This study aimed to evaluate the relationship between thalassemia disease and body mass index (BMI) and the correlation with blood group of thalassemia patients.Methods: The study includes 260 persons (male+female), 200 persons were thalassemia patient (120 male and 80 female), and 60 healthy persons (30 male and 30 female) as control group; furthermore, people were divided into three group according to age 1–9, 10–19, and >20 years, and BMI and blood group were measured for all patients and healthy people.Results: The results showed that the frequency of thalassemia in male (65%) is higher than in female (40%); as well as, the results showed that the age group (10–19) years is more frequent in male, while in female, the age group (1–9) years is more frequent. The results of BMI revealed a significant decrease (p<0.05) in all groups of thalassemia patients compared with healthy group; as well as, the results of blood group showed that the group (O+) is the more frequent 34% in comparison with the other blood groups.Conclusion: We conclude that there was a strong relationship among gender, blood group (the most common blood group observed is O +ve), and BMI with thalassemia.


GYNECOLOGY ◽  
2019 ◽  
Vol 21 (4) ◽  
pp. 14-18
Author(s):  
Dmitry V Gusev ◽  
Sergey Yu Kuznetsov ◽  
Tatyana Yu Ivanets ◽  
Galina E Chernukha

Aim. To investigate the usefulness of differential diagnostic criteria of functional hypothalamic amenorrhea (FHA) related to energy deficiency and stress. Materials and methods. There were provided clinical and laboratory examination of 56 patients with FHA associated with stressful events (group 1) and 64 patients with FHA on the background of eating disorders (group 2), including assessment of adipose tissue, determination of leptin level, adipose tissue index and differential index. Results. Patients of group 2 were distinguished by a more significant deficiency of body mass index, total body fat, and leptin levels in comparison with patients of group 1. The differential index [AUC=0.907 (0.84-0.97)] turned out to be the most informative indicator in the differential diagnosis of various forms of FHA, its threshold value was 21.4, the least informative - body mass index [AUC=0.78 (0.71-0.87)]. Conclusion. The differential index can be considered as an informative differential diagnostic criterion for various forms of FHA.


2019 ◽  
Author(s):  
Alfredo Santovito ◽  
Gabriella Galli ◽  
Stefano Ruberto

ABSTRACTBackgroundlongevity is considered the result of interactions between environmental and genetic factors.Aimwe investigated the possible association of body mass index and the frequencies ofAPOE, ACE, eNOS, andFTOgene polymorphisms with longevity.Subjects and Method1,100 healthy volunteers aged 10-100 were recruited. We genotyped subjects forAPOE, ACE, eNOS, andFTOgene polymorphisms. Data about height and weight were also collected. The sample was split in four age groups: 1-24, 25-49, 50-85 and 86-100.Resultssignificant differences were found in BMI values between age groups, with exception of 1-24 with respect to 86-100. A significant decrease of theAPO E4, eNOS 393andFTO Aand allele frequencies was observed in the 86-100 age group with respect to younger groups. ForACEgene, no significant differences were found in the allele frequencies between groups. A similar trend was also observed subdividing the sample in two main age groups: 1-85 and 86-100.Conclusionthis study provides evidences for a role ofAPOE, eNOS, andFTOgene polymorphisms in longevity. It has been estimated that the number of centenarians worldwide will double each decade until 2100, making population data about gene polymorphisms relevant for further studies about longevity.


2017 ◽  
Vol 89 (3) ◽  
pp. 219 ◽  
Author(s):  
Mehmet Zeynel Keskin ◽  
Salih Budak ◽  
Evrim Emre Aksoy ◽  
Cem Yücel ◽  
Serkan Karamazak ◽  
...  

Aim: To evaluate the effects of body mass index (BMI) ratio on semen parameters and serum reproductive hormones. Materials and methods: The data of 454 patients who prsented to male infertility clinics in our hospital between 2014 and 2015 were analyzed retrospectively. Weight, height, serum hormone levels and semen analysis results of the patients were obtained. BMI values were calculated by using the weight and height values of the patients and they were classified as group 1 for BMI values ≤ 25 kg/m2, as group 2 for BMI values 25-30 kg/m2 and as group 3 for BMI values ≥ 30 kg/m2. Results: The mean values of BMI, semen volume, concentration, total motility, progressive motility, total progressive motile sperm count (TPMSC), normal morphology according to Kruger, head abnormality, neck abnormality, tail abnormality, FSH, LH, prolactin, T/E2, total testosterone and estradiol parameters of the patients were considered. Patients were divided according to BMI values in Group 1 (n = 165), Group 2 (n = 222) and Group 3 (n = 56). There was no statistically significant difference in terms of all variables between the groups. Conclusions: We analyzed the relationship between BMI level and semen parameters and reproductive hormones, demonstrating no relationship between BMI and semen parameters. In our study, BMI does not affect semen parameters although it shows negative correlation with prolactin and testosterone levels.


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