scholarly journals Bariatric surgery metabolic effects

2019 ◽  
Vol 10 (2) ◽  
pp. 99-109
Author(s):  
Konstantin K. Mirchuk ◽  
Dmitriy I. Vasilevskiy ◽  
Kristina A. Anisimova ◽  
Leysan I. Davletbaeva

Obesity is considered now as a chronic relapsing lifelong disease, with a tendency to progression. According to the WHO, it present about 60% of the population of economically developed countries is overweight, 25-30% – is obesity. Russia is in fifth place in the world in the prevalence of obesity and overweight, being second only to the United States, Mexico, Hungary and Scotland. According to the Research Institute of Nutrition in the North-West region of the Russian Federation, 29.7% of women and 18.5% of men are overweight. Associated with obesity diseases include atherosclerosis, type 2 diabetes, hypertension, coronary heart disease, hormonal disorders, some cancers, etc. In proportion to the number of obese people increases and the incidence of pathological conditions associated with overweight. The vast majority of 95% of obese people die from causes directly related to overweight. The life expectancy of patients with overweight is reduced by 10-20 years, depending on the age of development and severity of obesity. The effectiveness of the conservative methods of correction associated with overweight in the arsenal of medicine today is low due to the complexity of the impact on their main cause – overweight. The article presents modern ideas about the mechanisms of action, hormonal and metabolic effects of the main types of bariatric operations. High long-term efficacy of surgical treatment of obesity-associated dis-orders of lipid and carbohydrate metabolism, arterial hypertension has been shown.

2020 ◽  
Vol 1 (1) ◽  
pp. 42-55
Author(s):  
José G. Vargas-Hernández ◽  
Icela Flores Osuna ◽  
Omar Vargas-González

Purpose: Mexico, like other countries, invested in measures to attract foreign direct investment to its territories. It, therefore, signed the North American Free Trade Agreement (NAFTA) in 1994, a treaty that facilitated Mexico to be the largest direct exporter to the United States. However, in 2018 the agreement was renegotiated and replaced with United States–Mexico–Canada Agreement (USMCA). This research is carried out to determine the advantages and disadvantages of renegotiation for Sinaloa's agricultural exports, with the question of whether it would negatively impact the Sinaloa's agricultural exports. Methods: The study focuses on the impact of renegotiation of the NAFTA on agricultural exports of the state of Sinaloa with indicators such as the Exports-Trade, GDP, and GDP Per capita of Mexico, opening to new markets, and logistics. Results: The renegotiation has a direct relationship with agricultural production in Sinaloa, with a serious negative effect, since overproduction would be created if the new destination for exporting from Sinaloa was not quickly available. Implications: This research can be of much use to the main agricultural exporting companies in Sinaloa, government agencies, and the Sinaloa Chambers of Commerce for decision making and policy formulation.


2016 ◽  
Author(s):  
M. Venkat Ratnam ◽  
S. Ravindra Babu ◽  
S. S. Das ◽  
Ghouse Basha ◽  
B. V. Krishnamurthy ◽  
...  

Abstract. Tropical cyclones play an important role in modifying the tropopause structure and dynamics as well as stratosphere-troposphere exchange (STE) process in the Upper Troposphere and Lower Stratosphere (UTLS) region. In the present study, the impact of cyclones that occurred over the North Indian Ocean during 2007–2013 on the STE process is quantified using satellite observations. Tropopause characteristics during cyclones are obtained from the Global Positioning System (GPS) Radio Occultation (RO) measurements and ozone and water vapor concentrations in UTLS region are obtained from Aura-Microwave Limb Sounder (MLS) satellite observations. The effect of cyclones on the tropopause parameters is observed to be more prominent within 500 km from the centre of cyclone. In our earlier study we have observed decrease (increase) in the tropopause altitude (temperature) up to 0.6 km (3 K) and the convective outflow level increased up to 2 km. This change leads to a total increase in the tropical tropopause layer (TTL) thickness of 3 km within the 500 km from the centre of cyclone. Interestingly, an enhancement in the ozone mixing ratio in the upper troposphere is clearly noticed within 500 km from cyclone centre whereas the enhancement in the water vapor in the lower stratosphere is more significant on south-east side extending from 500–1000 km away from the cyclone centre. We estimated the cross-tropopause mass flux for different intensities of cyclones and found that the mean flux from stratosphere to troposphere for cyclonic stroms is 0.05 ± 0.29 × 10−3 kg m−2 and for very severe cyclonic stroms it is 0.5 ± 1.07 × 10−3 kg m−2. More downward flux is noticed in the north-west and south-west side of the cyclone centre. These results indicate that the cyclones have significant impact in effecting the tropopause structure, ozone and water vapour budget and consequentially the STE in the UTLS region.


Author(s):  
Earl H. Fry

This article examines the ebb and flow of the Quebec government’s economic and commercial relations with the United States in the period 1994–2017. The topic demonstrates the impact of three major forces on Quebec’s economic and commercial ties with the US: (1) the North American Free Trade Agreement (NAFTA) which became operational in 1994 and was fully implemented over a 15-year period; (2) the onerous security policies put in place by the US government in the decade following the horrific events of 11 September 2001; and (3) changing economic circumstances in the United States ranging from robust growth to the worst recession since the Great Depression of the 1930s. The article also indicates that the Quebec government continues to sponsor a wide range of activities in the United States, often more elaborate and extensive than comparable activities pursued by many nation-states with representation in the US. 1 1 Stéphane Paquin, ‘Quebec-U.S. Relations: The Big Picture’, American Review of Canadian Studies 46, no. 2 (2016): 149–61.


Finisterra ◽  
2012 ◽  
Vol 31 (62) ◽  
Author(s):  
Andrew Pike ◽  
Mário Vale

The industrial policy in the UK and in Portugal, as in most EU countries, seeks to attract new investment capacity, to create jobs and to promote the impact of the so-called "demonstration efect" of "greenfield" development strategies pursued in the new plants of inward investors on existing or "brownfield" plants. This industrial policy focus is particularly evident in the automobile industry.This paper compares the industrial policy oriented towards the automobile industry in the UK and in Portugal. Two recent "greenfield" investments are analised: Nissan in the North-East region (UK) and Ford/VW in the Setúbal Peninsula (Portugal), as well as three "brownfield" plants: Ford Halewood and GM Vauxhall Ellesmere Port in the North-West region (UK) and Renault in Setúbal (Portugal). The first part starts with a discussion of industrial policy in the automobile sector, the role of "greenfield" development strategies and the "demonstration effect" on "brownfield" plants. Then, the limits of new inward investment are pointed out, basically their problems and restrictions. Afterwards, the structural barriers to the "demonstration effect" within "brownfield" plants are outlined and some possabilities for alternative "brownfield" development strategies are presented.


Author(s):  
Oleh Bulka

The article is devoted to the particularity of Canada-Mexico bilateral relations in the period from their beginning to signing and entry into force the North American Free Trade Agreement (NAFTA). It is noted that from the time of first contacts bilateral relations between two countries have developed unevenly with periods of increase and periods of decline. It is determined that in the history of Canada-Mexico relations before signing NAFTA can be identified four main periods. The first one is a period of early contacts that lasted from the end of XIX century to the establishment of the official diplomatic relations between Canada and Mexico in 1944. In this period of time ties between the two countries were extremely weak. The second period lasted from 1944 to the end of the 1960s. This period clearly shows the limits of cooperation between Canada and Mexico after the establishment of the official diplomatic ties, but it is also possible to see a certain coincidence between the values and diplomatic strategies of these countries. The third period of Canada-Mexico relations lasted from the beginning of the 1970s to the end of the 1980s. During this period, both Canada and Mexico try to diversify their foreign policy and strengthen the organizational mechanism of mutual cooperation. But it is also shown that despite the warm political rhetoric, there was some distance in Canada-Mexico relations. The fourth period of the relations lasted from the late 1980s until the NAFTA treaty came into force in 1994. At that time Canadian and Mexican governments began to give priority to economic relations over political and diplomatic ones. It was revealed that the main influencing factors of bilateral relations between Mexico and Canada were the impact of third countries, especially the United Kingdom and the United States, regional and global economic conditions, and the attitude to the bilateral relations of the political elites of both countries.


2019 ◽  
Author(s):  
Maile T. Phillips ◽  
Katharine A. Owers ◽  
Bryan T. Grenfell ◽  
Virginia E. Pitzer

ABSTRACTBackgroundInvestments in water and sanitation systems are believed to have led to the decline in typhoid fever in developed countries, such that most cases now occur in regions lacking adequate clean water and sanitation. Exploring seasonal and long-term patterns in historical typhoid mortality in the United States can offer deeper understanding of disease drivers.MethodsWe fit modified Time-series Susceptible-Infectious-Recovered models to city-level weekly mortality counts to estimate seasonal and long-term typhoid transmission. We examined seasonal transmission separately by city and aggregated by water source. We fit regression models to measure associations between long-term transmission and financial investments in water and sewer systems.ResultsTyphoid transmission peaked in late summer/early fall. Seasonality varied by water source, with the greatest variation occurring in cities with reservoirs. Historical $1 per capita ($25.80 in 2017) investments in construction and operation of water and sewer systems were associated with 8-53% decreases in typhoid transmission, while $1 increases in total value or debt accrued to maintain them were associated with 4-7% decreases.ConclusionOur findings aid in the understanding of typhoid transmission dynamics and potential impacts of water and sanitation improvements, and can inform cost-effectiveness analyses of interventions to reduce the typhoid burden.


Author(s):  
A.V. Goncharenko ◽  
T.O. Safonova

The article investigates the impact of Great Britain on the evolution of colonialism in the late ХІХ and early ХХ centuries. It is analyzed the sources and scientific literature on the policy of the United Kingdom in the colonial question in the late ХІХ – early ХХ century. The reasons, course and consequences of the intensification of British policy in the colonial problem are described. The process of formation and implementation of London’s initiatives in the colonial question during the period under study is studied. It is considered the position of Great Britain on the transformation of the colonial system in the late XIX – early XX centuries. The resettlement activity of the British and the peculiarities of their mentality, based on the idea of racial superiority and the new national messianism, led to the formation of developed resettlement colonies. The war for the independence of the North American colonies led to the formation of a new state on their territory, and the rest of the “white” colonies of Great Britain had at the turn of the XIX-XX centuries had to build a new policy of relations, taking into account the influence of the United States on them, and the general decline of economic and military-strategic influence of Britain in the world, and the militarization of other leading countries. As a result, a commonwealth is formed instead of an empire. With regard to other dependent territories, there is also a change in policy towards the liberalization of colonial rule and concessions to local elites. In the late ХІХ – early ХІХ centuries the newly industrialized powers (Germany, Italy, and Japan) sought to seize the colonies to reaffirm their new status in the world, the great colonial powers of the past (Spain, Portugal, and the Netherlands) sought to retain what remained to preserve their international prestige, and Russia sought to expand. The largest colonial empires, Great Britain and France, were interested in maintaining the status quo. In the colonial policy of the United Kingdom, it is possible to trace a certain line related to attempts to preserve the situation in their remote possessions and not to get involved in conflicts and costly measures where this can be avoided. In this sense, the British government showed some flexibility and foresight – the relative weakening of the military and economic power of the empire due to the emergence of new states, as well as the achievement of certain self-sufficiency, made it necessary to reconsider traditional foreign policy. Colonies are increasingly no longer seen as personal acquisitions of states, and policy toward these territories is increasingly seen as a common deal of the international community and even its moral duty. The key role here was to be played by Great Britain, which was one of the first to form the foundations of a “neocolonial” system that presupposes a solidarity policy of Western countries towards the rest of the world under the auspices of London. Colonial system in the late ХІХ – early ХІХ century underwent a major transformation, which was associated with a set of factors, the main of which were – the emergence of new industrial powers on the world stage, the internal evolution of the British Empire, changes in world trade, the emergence of new weapons, general growth of national and religious identity and related with this contradiction. The fact that the First World War did not solve many problems, such as Japanese expansionism or British marinism, and caused new ones, primarily such as the Bolshevik coup in Russia and the coming to power of the National Socialists in Germany, the implementation of the above trends stretched to later moments.


Pakistan ◽  
2020 ◽  
pp. 131-144
Author(s):  
Mariam Abou Zahab

This chapter attempts to analyse the dynamics of the Pashtun–Punjabi nexus and the areas of competition and cooperation between Sunni sectarian groups and the Pakistani Taliban. It outlines the links between Sunni sectarian groups and the Afghan Taliban, the impact of the collapse of the Taliban regime in Afghanistan and the implications of the relocation of Punjabi jihadi/sectarian groups in the North West Frontier Province (NWFP) and the Federally Administered Tribal Areas (FATA). It also focuses on the consequences of the storming of Islamabad's Lal Masjid in July 2007, and it investigates the re-emergence of sectarian groups in Karachi and in the Punjab and its implications for Pakistan. The Punjab and Karachi have been the primary hubs of sectarian violence in Pakistan since the 1980s, but in the post-9/11 environment the Sunni-Shia conflict has assumed a new dimension.


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