Acupuncture Combined with Electromyographic Biofeedback Improves Limb Disturbance, Depression and Quality of Life of Stroke Patients

This study was designed to probe into the effects of acupuncture combined with electromyographic (EMG) biofeedback on limb dysfunction, depression and quality of life of stroke patients.Altogether 104 cerebral infarction patients who admitted to our hospital were selected as the research objects. According to different treatment schemes, 53 patients were divided into observation group (OG) (acupuncture combined with electromyographic biofeedback) and 50 were enrolled into control group (CG) (acupuncture alone). The treatment efficacy, National Institute of Health Stroke Scale (NIHSS), clinical spasm index (CSI), Berg balance scale (BBS), Fugl-Meyer Assessment (FMA), Timed Up and Go test (TUG), treatment compliance, depression and quality of life of the two groups were evaluated, and their adverse reactions during treatment were recorded and compared.The efficacy of the OG was obviously better than that of the CG (P<0.05). After treatment, NIHSS, CSI, BBS, FMA, TUG, treatment compliance, depression and quality of life of the two groups were dramatically improved (P<0.05), but the improvement degree of the OG was markedly better than that of the CG (P<0.05). There was no remarkable difference in adverse reactions between the two groups during treatment (P>0.05).EMG biofeedback combined with acupuncture has good efficacy on stroke, which can effectively improve limb dysfunction, relieve patients’ negative emotions and improve their quality of life. It is safe and worthy of clinical promotion.

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Equilíbrio, mobilidade funcional e qualidade de vida em idosos participantes e não participantes de um centro de convivência

Scientia Medica ◽

10.15448/1980-6108.2017.4.27400 ◽

2017 ◽

Vol 27 (4) ◽

pp. 27400

Author(s):

Maiara Lohn Farias ◽

Lisiane Piazza Luza ◽

Bianca Andrade Sousa ◽

Ediane Roberge Zampirolo

Keyword(s):

Quality Of Life ◽

Elderly People ◽

Senior Citizen ◽

Berg Balance Scale ◽

Functional Mobility ◽

Control Group ◽

Timed Up And Go ◽

Balance Scale ◽

Sf 36

***Balance, functional mobility and quality of life in eldery participants and non-participants of a community center***AIMS: To evaluate balance, functional mobility and quality of life in elderly participants and non-participants of a senior citizen center.METHODS: Subjects aged 60 or over, participating in a senior citizen center in the city of Santo Amaro da Imperatriz, in Santa Catarina (Participating Group: PG) were evaluated. As a control group for comparison, elderly residents of the same community who did not participate in any senior center (Non-Participating Group: NPG) were included. Subjects with locomotion disabilities, neurological diseases that affected the gait or balance, and inability to understand the general commands indispensable to the tests were excluded. The sample was non-probabilistic intentional. To evaluate the balance, the Berg Balance Scale was applied, and for assess functional mobility we used the Timed Up and Go and the Anterior Functional Scope tests. Quality of life was assessed by the SF-36 questionnaire. The data were treated by descriptive and inferential statistics, considering p≤0.05 as significant.RESULTS: Fifty-six elderly participated, being 28 of PG and 28 of NPG. By means of the Berg Balance Scale, we found a better balance in PG (mean 53.2±2.1 points) compared to NPG (mean 48.8±6.2 points) (p=0.001). In the Timed Up and Go test, PG spent in average less time to perform the test (9.5±1.5 seconds) than NPG (13.1±5.1 seconds) (p=0.001). We observed a better quality of life in all domains of SF-36 in PG when compared to NPG (p<0.05).CONCLUSIONS: Elderly people who participated in a senior citizen center presented better balance, functional mobility and quality of life than elderly people from the same community who did not participate in senior centers.

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Insulin Glargine and Acarbose in the treatment of elderly patients with diabetes

Pakistan Journal of Medical Sciences ◽

10.12669/pjms.35.3.86 ◽

2019 ◽

Vol 35 (3) ◽

Author(s):

Jing Li ◽

Jinzhi Ji ◽

Fuyan Liu ◽

Lingling Wang

Keyword(s):

Quality Of Life ◽

Blood Glucose ◽

Elderly Patients ◽

Insulin Glargine ◽

Adverse Reactions ◽

Postprandial Blood Glucose ◽

Control Group ◽

Observation Group ◽

Patients With Diabetes

Objective: To investigate the clinical efficacy of insulin glargine combined with acarbose in the treatment of elderly patients with diabetes. Methods: One hundred and forty-four elderly patients with diabetes who received treatment between December 2016 and December 2017 in Binzhou People’s Hospital, China, were selected and divided into a control group and an observation group, 72 each, using random number table. The control group was treated with insulin glargine, while the observation group was treated with insulin glargine combined with acarbose. The therapeutic effect, improvement of quality of life and adverse reactions were compared between the two groups. Results: After treatment, fasting blood glucose (FBG), 2h postprandial blood glucose (PBG) and glycosylated hemoglobin (Hb Alc) of the two groups were lower than those before treatment, and the decrease degree of the observation group was significantly larger than that of the control group (P<0.05). The time needed for blood glucose reaching the standard level and daily insulin dosage of the observation group were significantly lower than that of the control group, and the differences were statistically significant (P<0.05). SF-36 scale score of the observation group was significantly better than the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The combination of insulin Glargine and Acarbose can significantly control the blood glucose level of elderly patients with diabetes, improve the biochemical indicators, and enhance the quality of life. It is worth promotion in clinical practice. doi: https://doi.org/10.12669/pjms.35.3.86 How to cite this:Li J, Ji J, Liu F, Wang L. Insulin Glargine and Acarbose in the treatment of elderly patients with diabetes. Pak J Med Sci. 2019;35(3):---------. doi: https://doi.org/10.12669/pjms.35.3.86 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Transurethral Resection of Prostate for the Treatment of Advanced Prostate Cancer and Bladder Outlet Infarction

Proceedings of Anticancer Research ◽

10.26689/par.v1i2.19 ◽

1970 ◽

Vol 1 (2) ◽

Author(s):

Chenglin Huang

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Endocrine Therapy ◽

Transurethral Resection ◽

Advanced Prostate Cancer ◽

Control Group ◽

Transurethral Resection Of Prostate ◽

Study Group ◽

Better Than

Objective: To investigate the feasibility of transurethral resectionÂ of prostate and theÂ treatment of advanced prostate cancer andÂ bladder outlet infarction, and to analyze the therapeutic effect.Â Methods: 34 patients with advanced prostate cancer admitted inÂ our hospital from April 2014 to April 2014 were divided intoÂ control group (17 cases) with routineÂ endocrine therapy. The studyÂ group (17 cases) underwent urethral resection surgeryÂ CombinedÂ with endocrine therapy, through the relevant indicators of prostateÂ treatment were observed to explore the two groups of patients withÂ therapeutic effect. Results:Â According to the related indexes ofÂ prostate treatment, the treatment effect of the study group wasÂ significantly better than that of the control group, and the data ofÂ the two groups were statistically significant (P<0.05). Conclusion:Â The treatment of advanced prostate cancer patients with endocrineÂ combined with transurethral resection of the prostate canÂ effectively treat the symptoms of bladder outlet infarction andÂ improve the quality of life of patients. It has certain value inÂ clinical treatment.

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The Effect of Combination Use of Hemodialysis and Hemoperfusion on Microinflammation in Elderly Patients with Maintenance Hemodialysis

Blood Purification ◽

10.1159/000518857 ◽

2022 ◽

pp. 1-8

Author(s):

Jun Li ◽

Hui Li ◽

Wenjiao Deng ◽

Lixin Meng ◽

Wenya Gong ◽

...

Keyword(s):

Quality Of Life ◽

Elderly Patients ◽

Adverse Reactions ◽

Statistical Significance ◽

Continuous Treatment ◽

Maintenance Hemodialysis ◽

Control Group ◽

Observation Group ◽

Significant Difference

Background: Patients with maintenance hemodialysis (MHD) generally have a microinflammatory state. The aim of this study was to investigate the effects of hemodialysis (HD) combined with hemoperfusion (HP) on microinflammatory state in elderly patients with MHD. Methods: One hundred and fifty elderly patients with MHD were randomly divided into the control group and the observation group. The control group received simple HD treatment, and the observation group received combined HD + HP treatment on the basis of the control group. After 6 months of continuous treatment, the patients were evaluated to compare the quality of life, inflammation, adverse reactions, and nutritional indicators in the 2 groups before and after treatment. Results: There was no significant difference in the quality of life between the 2 groups before treatment. After treatment, the scores of psychological aspects, physiological aspects, social aspects, environmental aspects, and independent ability in the observation group were higher than those in the control group, with statistical significance (p < 0.05). There was no statistical significance in the level of inflammation between 2 groups before treatment. After treatment, the levels of hs-CRP, Hcy, IL-6, and TNF-α in the observation group were significantly lower than those in the control group, with statistical significance (p < 0.05). The incidence of dry mouth, skin reaction, neuritis, and subcutaneous tissue fibrosis in the observation group was lower than that in the control group, with statistical significance (p < 0.05). There was no statistical significance in nutritional level indexes between 2 groups before treatment (p1 > 0.05). After treatment, the levels of hemoglobin, total protein, albumin, and transferrin in the observation group were significantly higher than those in the control group, with statistical significance (p < 0.05). Conclusion: The clinical effect of HD combined with HP in elderly MHD patients is significant, which can effectively reduce the incidence of adverse reactions and inflammation in the patients and improve the quality of life and nutritional indicators of the patients.

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CTNI-28. A PROSPECTIVE, OBSERVATIONAL STUDY EVALUATING THE SAFETY AND QUALITY OF LIFE OF TUMOR TREATING FIELDS IN CHINESE GLIOBLASTOMA PATIENTS

Neuro-Oncology ◽

10.1093/neuonc/noaa215.195 ◽

2020 ◽

Vol 22 (Supplement_2) ◽

pp. ii48-ii48

Author(s):

Kevin Wong ◽

Tao Jiang

Keyword(s):

Quality Of Life ◽

Adverse Reactions ◽

Clinical Manifestations ◽

Treatment Compliance ◽

Symptomatic Treatment ◽

Chinese Patients ◽

Published Data ◽

Newly Diagnosed ◽

Tumor Treating Fields

Abstract OBJECTIVES Glioblastoma (GBM) is the most common and aggressive primary brain tumor with a median survival of 15 months. Adding Tumor Treating Fields (TTFields) to first-line therapy in GBM demonstrated improved survival in the EF-14 trial. This prospective study was designed to investigate the safety and effect on QoL of TTFields in Chinese patients with GBM. METHODS A total of 44 patients (29 newly diagnosed GBM, 15 recurrent GBM, median age 51.0 [24.0 - 81.0] years) who underwent TTFields following surgery, concurrent chemoradiotherapy were enrolled into the study. The primary endpoint was the incidence of TTFields-related skin adverse events; the secondary endpoint included quality of life (QoL), treatment adherence. RESULTS Of the 44 patients followed up for at least 3 months, 24 (54.5%) had skin adverse reactions, all of which were grade 1–2. Median time to skin AE was 1.2 months. The common skin AE were dermatitis (53.8%), ulcer (19.2%), infection (19.2%), and most of them could be resolved by symptomatic treatment (topical corticosteroid/antibiotics). In terms of QoL, noticeable improvement in overall health and clinical manifestations such as fatigue, nausea and vomiting were observed. The overall average treatment compliance was 91%: compliance (mean±SD), in newly diagnosed patients, 0.89±0.14, median 0.91; in recurrent patients, 0.86±0.13, median 0.93. CONCLUSIONS The incidence of skin adverse reactions (which could be effectively alleviated with treatment) in GBM patients treated with TTFields was acceptable. From our short follow up, TTFields appear to improve QoL and compliance in Chinese patients comparable to published data.

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Effect of Psychological Intervention Combined with Dietary Guidance on Quality of Life and Long-Term Efficacy of Bushen Quyu Decoction in Treatment of Patients with Advanced Ovarian Cancer

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2021/1075513 ◽

2021 ◽

Vol 2021 ◽

pp. 1-8

Author(s):

Dan Liu ◽

Guangwen Shi ◽

Chao Yin ◽

Zhendong Liu ◽

Aixia Yang

Keyword(s):

Quality Of Life ◽

Ovarian Cancer ◽

Psychological Intervention ◽

Advanced Ovarian Cancer ◽

Treatment Compliance ◽

Control Group ◽

Observation Group ◽

Nursing Satisfaction

Objective. To study the effects of psychological intervention combined with dietary guidance on the quality of life and long-term efficacy of Bushen Quyu Decoction in the treatment of patients with advanced ovarian cancer. Methods. 220 patients with advanced (stages III to IV) ovarian cancer in our hospital from May 2015 to October 2018 were selected and randomly divided into a control group and an observation group, with 110 cases in each group. The patients in the control group received basic nursing care and treatment with Bushen Quyu Decoction, and the patients in the observation group were combined with psychological intervention and dietary guidance on the basis of the treatment of the patients in the control group. The clinical efficacy, nursing satisfaction, treatment compliance, quality of life, negative emotion comparison, and long-term efficacy of the two groups were compared. Moreover, the changes of immune function indexes and the content of tumor markers were compared between the two groups. Results. The total effective rate of treatment in the observation group (64.55%) was higher than that in the control group (31.82%). The nursing satisfaction of the observation group was 94.55%, the nursing satisfaction of the control group was 84.55%, and the difference was statistically significant p < 0.01 . The treatment compliance of the observation group was 98.18%, the treatment compliance of the control group was 82.73%, and the difference was statistically significant p < 0.0001 . After nursing, the Anxiety Self-Rating Scale (SAS) score and Self-Rating Depression Scale (SDS) score of the two groups of patients were decreased ∗ p < 0.05 , and the score of the observation group decreased more significantly p Δ < 0.05 . After nursing, the scores of the two groups of patients in social/family status, physical function, physiological function, and emotional status increased ∗ p < 0.05 , and the observation group was significantly higher than the control group p Δ < 0.05 . After nursing, the CD3+, CD4+, CD4+/CD8+ levels of the observation group were significantly higher than the control group p < 0.05 . The CD8+ level of the observation group was significantly lower than the control group p < 0.05 . After nursing, the levels of tumor markers in the two groups were decreased ∗ p < 0.05 , and the observation group was downregulated more significantly than the control group p Δ < 0.05 . The two-year cumulative survival rate of the observation group was 78.18%, and the two-year cumulative survival rate of the control group was 54.55%. The observation group was significantly higher than the control group p < 0.05 . Conclusions. Psychological intervention combined with dietary guidance can significantly improve the quality of life and mental state of patients with advanced ovarian cancer, enhance the patient’s immune function, reduce the serum tumor markers carcinoembryonic antigen (CEA) and carbohydrate antigen (CA199) levels, and improve survival rate and survival time, which has important clinical significance.

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Fast-velocity resistance training improves force development and mobility in Multiple Sclerosis

International Journal of Sports Medicine ◽

10.1055/a-1710-1492 ◽

2021 ◽

Author(s):

Luis Andreu-Caravaca ◽

Domingo Jesús Ramos-Campo ◽

Linda H. Chung ◽

Pedro Manonelles ◽

Joao Paulo Vilas Boas ◽

...

Keyword(s):

Quality Of Life ◽

Multiple Sclerosis ◽

Resistance Training ◽

Rate Of Force Development ◽

Control Group ◽

Timed Up And Go ◽

Force Development ◽

Sit To Stand ◽

Experimental Group

This study aimed to analyze the benefits of a lower-limb fast-velocity concentric resistance training on rate of force development, mobility, and quality of life in people with Multiple Sclerosis. A randomized controlled trial was conducted in 30 people with Multiple Sclerosis, who were randomly assigned to either an experimental (n=18) or a control (n=12) group. The experimental group carried out 10-weeks of fast-velocity concentric resistance training, while the control group did not perform any intervention. Early and late rate of force development during knee extension in both legs, sit-to-stand and Timed Up and Go tests and quality life questionnaire were evaluated before and after intervention. The training program evoked an increase in early rate of force development in experimental group (0-30; Rightleg: 63.9%, p<0.001;ES=-1.4; Leftleg: 52.7%, p<0.001;ES=-1.0) compared to control group (showed modest increases). Furthermore, experimental group improved mobility after training (Sit-to-stand: 22.2%, p<0.001;ES=1.0; Timed Up and Go Test: 10.1%, p<0.001;ES=1.1) and increased the perception of quality of life after training, while control showed no changes. The fast-velocity concentric resistance training has the potential to improve early rate of force development and mobility after 10-weeks of training. In addition, the increase in self-perceived quality of life following this training modality demonstrates promising results in the Multiple Sclerosis population.

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Short-Term Efficacy and Quality of Life of Gastric Cancer Patients Undergoing Radical Gastrectomy Assisted by External Vision

Computational and Mathematical Methods in Medicine ◽

10.1155/2021/4256347 ◽

2021 ◽

Vol 2021 ◽

pp. 1-6

Author(s):

Jian Zheng ◽

Yingwei Xue ◽

Chunfeng Li

Keyword(s):

Quality Of Life ◽

Gastric Cancer ◽

Cancer Patients ◽

Control Group ◽

Observation Group ◽

Radical Gastrectomy ◽

The Difference ◽

Gastric Cancer Patients ◽

Better Than

Objective. To evaluate the clinical effects and survival prognosis of radical gastrectomy assisted by external vision in gastric cancer. Methods. A total of 60 hospitalized gastric cancer patients from June 2016 to December 2018 were selected and divided into the observation group and control group according to different surgical procedures. The control group was treated with traditional open radical gastrectomy, while the observation group was treated with radical gastrectomy assisted by an external vision microscope. Relevant surgical indicators, visual analogue scale (VAS), postoperative complications, and life quality assessment were analyzed and compared between the two groups. Results. The incision length and intraoperative blood loss in the observation group were smaller than those in the control group, and the difference was statistically significant ( P < 0.05 ); compared with the control group, the observation group had significantly shorter hospital stay, earlier postoperative first exhaust time, and lower gastric fluid volume at the 3rd day after surgery ( P < 0.05 ). The pain scores of the observation group at 1, 4, and 12 weeks after surgery were lower than those of the control group ( P < 0.05 ), and the difference was significant. The quality of life scores at the 1st week and 12th week after surgery showed that the dysphagia symptom scores of the observation group and the control group were significantly reduced but the two groups had significant differences in fatigue, physical function, pain score, postoperative pain, and overall quality of life. The observation group was significantly better than the control group ( P < 0.05 ). Follow-up studies showed no significant difference between mortality and cancer recurrence ( P > 0.05 ); the patients recovered well at postoperation, and the diet of the observation group was better than that of the control group ( P < 0.05 ); gastric reflux and knife pain were less than those of the control group ( P < 0.05 ). Conclusion. Radical gastrectomy assisted by external vision for gastric cancer yields clinical benefits for gastric cancer patients, which not only dramatically shortened the length of hospital stay but also effectively ameliorated the quality of life of patients, all indicating that external vision-assisted surgery was significantly better than traditional gastrectomy in improving the postoperative quality of life of gastric cancer patients in the absence of increasing the risk of adverse events.

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Comparative analysis of use of triamcinolone and placebo in treatment of persistent allergic rhinitis

Russian otorhinolaryngology ◽

10.18692/1810-4800-2021-1-61-64 ◽

2021 ◽

Vol 20 (1) ◽

pp. 61-64

Author(s):

A. Kh. Nazanyan ◽

◽

S. L. Manasyan ◽

A. A. Avakyan ◽

A. K. Shukuryan ◽

...

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Study Groups ◽

Control Group ◽

Study Group ◽

Persistent Allergic Rhinitis ◽

The Difference ◽

Double Blinded ◽

Better Than

The aim of the study was to determine the effect of triamcinolone monotherapy on the quality of life of patients with persistent allergic rhinitis. The study was placebo-controlled, randomized and double-blinded. The study included 46 patients in the study group and 24 patients in the control group, all were diagnosed with persistent allergic rhinitis for at least two years. Patients were examined twice after diagnosis was made. The study group was administered intramuscularly with 40 mg of triamcinolone once, while the control group was given placebo. To estimate the quality of life in both groups, a specially designed questionnaire was used, according to which the final scores were calculated. The triamcinolone group had a lower overall score on the questionnaire compared with the placebo group (p < 0.001). The difference between the scores at the beginning of the study and at the end of the first month for all indicators was statistically significant (p < 0,001). The difference in changes from the start of the study to the end of the first month (difference in treatment) between placebo and the study groups was statistically significant, in favour of the study group. Triamcinolone is a drug that improves the quality of life of patients treated for persistent allergic rhinitis, better than placebo.

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Quality of life, duration of the disease and the level of pain in patients with rheumatoid arthritis

Baltic Journal of Health and Physical Activity ◽

10.29359/bjhpa.09.1.08 ◽

2017 ◽

Vol 9 (1) ◽

pp. 72-80

Author(s):

EWA KUPCEWICZ ◽

AGNIESZKA DREJER

Keyword(s):

Quality Of Life ◽

Joint Pain ◽

Life Quality ◽

Control Group ◽

Physical Domain ◽

Life Domains ◽

Significance Level ◽

Perceived Pain ◽

Better Than

The aim of the present study is to evaluate life quality of people suffering from RA and determine the influence of illness duration and degree of pain intensity on their quality of life. The group of subjects comprised of 189 people: 104 (55.03%) with diagnosed RA and 85 (44.97%) healthy people as control group. Mean age in the group of ill subjects was 57.66 ±11.30 and 68 ±8.99 in the control group. In the research, self-constructed questionnaire, Visual Analogue Scale (VAS) and shortened version of WHOQoL-Bref were used. Assumed significance level was p < 0.05. Patients with RA received statistically significantly lower scores of life quality in all domains as compared with the control group. In the group of ill subjects, social domain (14.91 ±2.40) obtained highest scores whereas physical domain received lowest scores (11.96 ±1.69). The main somatic issue connected with the illness reported by 95.19% of subjects was experienced joint pain. Mean degree of perceived pain in VAS scale reached 7.37 ±1.86 points and it significantly lowered life quality of ill subjects. The results regarding life quality in four life domains (i.e. physical, psychological, social and environmental) were definitely better than in the control group.

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