scholarly journals The Interpretive Shaping of Music Performance Research

2013 ◽  
Vol 8 (2) ◽  
pp. 120 ◽  
Author(s):  
John Rink
Keyword(s):  
Empirical Research ◽  
Music Performance ◽  
Structural Features ◽  
Musical Performance ◽  
The Individual ◽  
Music Performance Research ◽  
Performance Research ◽  
Shed Light

<p>In their study of nine pianists Buck, MacRitchie and Bailey observe a universal embodiment of phrasing structure and other higher-level structural features of the music, the physical makeup of which is nevertheless particular to both the individual performers and the pieces they are performing. Such a conclusion invites renewed consideration of assumptions in the literature on musical performance about the nature and role of structure and about performers&rsquo; &lsquo;interpretations&rsquo; thereof. The findings also raise interesting questions about the musical viability of empirical research on performance and its capacity to shed light on how performers shape the music they play, their motivations in doing so, and how those listening to them might in turn be affected by this.</p>

scholarly journals The Role of Faith Systems and Religions in the Future of Sustainable Development: An Islamic Outlook

2019 ◽  
Vol 12 (5) ◽  
pp. 23
Author(s):  
Mamdouh M. A. Sobaihi
Keyword(s):  
Sustainable Development ◽  
Belief Systems ◽  
Distant Future ◽  
The Sustainable Development ◽  
Religious Networks ◽  
Development Plans ◽  
Development Goals ◽  
The Individual ◽  
Shed Light

Reference material concerning sustainable development has increased dramatically over the last decades, with more and more countries, agencies and businesses following the sustainable development ideals and principles. However, one of the most basic of human institutions has not contributed, and perhaps not allowed to contribute, to the debate. Religion and faith systems have a great potential in influencing not only the definitions of sustainable development but also concepts of human sustainable practices to achieve sustainable development goals. The main obstacle to the fulfillment of this potential appears to be the lack of outreach and acceptance of the scientific community to the religious and faith system institutions and individuals. In this paper, a review of the literature is carried out to shed light on the root of this schism between science and belief systems. In addition, the paper will highlight how the majority of the literature deals with process rather than the individual human being and how to make him/her a better practitioner of sustainability. It is also aimed that the paper shed some light on how religious and faith system ideals can be incorporated into sustainable development plans and systems. The main focus of the paper is to cast light on the religion of Islam and some of the Islamic teachings and Ideals and how they can be incorporated in delivering the message of sustainable development since the religion of Islam is forecast to be the largest faith on the planet in the not too distant future. In conclusion, a discussion on how the various religious networks can deliver the message of sustainability will be discussed.

The role of the Lewis acid−base properties in the supramolecular association of 1,2,5-chalcogenadiazoles

2013 ◽  
Vol 91 (5) ◽  
pp. 338-347 ◽  
Author(s):  
Anthony F. Cozzolino ◽  
Philip J.W. Elder ◽  
Lucia Myongwon Lee ◽  
Ignacio Vargas-Baca
Keyword(s):  
Topological Analysis ◽  
Structural Features ◽  
Lewis Acidity ◽  
Electron Localization ◽  
Dispersion Forces ◽  
Acid Base ◽  
Lewis Bases ◽  
The Individual ◽  
Secondary Bonding

The secondary bonding interactions that link the supramolecular structures assembled by 1,2,5-chalcogenadiazoles were analyzed through explicit orthogonalization of molecular orbitals (NBO), topological analysis of the electron density (AIM), and the electron localization function (ELF). The results of these analyses are consistent with a bonding description that attributes important covalent and electrostatic character to these interactions. Application of these analyses to the individual molecules highlighted the structural features from which each of those contributions originates, namely the polarity and modest strength of the E–N bond. Both of these effects increase along the series S, Se, Te. Perturbations to the heterocycle electronic structure that result in a weaker and more polar E–N bond cause an increase in the Lewis acidity at the chalcogen centre, which in turn leads to stronger secondary bonding interactions with Lewis bases. Additionally, the contribution of dispersion forces is not negligible and is most important in the case of sulfur.

Beyond legacy: Backstage stigmatisation and ‘trickle-up’ politics of urban regeneration

2018 ◽  
Vol 66 (4) ◽  
pp. 919-934 ◽  
Author(s):  
Kirsteen Paton
Keyword(s):  
Capital Accumulation ◽  
Private Business ◽  
Private Finance ◽  
Business Interests ◽  
Neoliberal Governance ◽  
East End ◽  
The Individual ◽  
Commonwealth Games ◽  
Shed Light

This article explores how stigmatisation is intimately linked with neoliberal governance and capital accumulation in specific ways through processes around the Glasgow Commonwealth Games. It advances the author’s previous research exploring the effects of stigma on the East End community hosting the Games, by looking at some of the processes of power and profit which motivate stigmatising processes by ‘gazing up’, rather than ‘gazing down’. That is, looking at the role of the stigmatisers in this project and not the stigmatised. It draws loosely on Goffman’s concept of ‘backstage’ to shed light on those who produce and profit from these stigmatisation processes, including government bodies and actors and private business interests. Looking at some of the processes through which stigmatisation is profited from reveals not only forms of power vital to this process but that it is a key form of exploitation integral to capital accumulation. Under austerity, the political economy of the Games constitutes state support of private finance and a simultaneous withdrawal of social welfare support, which transfers the burden of debt from the state to the individual and wealth from public funds to private funds.

scholarly journals Generation of protein kinase Ck1α mutants which discriminate between canonical and non-canonical substrates

2005 ◽  
Vol 391 (2) ◽  
pp. 417-424 ◽  
Author(s):  
Victor H. Bustos ◽  
Oriano Marin ◽  
Flavio Meggio ◽  
Luca Cesaro ◽  
Catherine C. Allende ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Structural Features ◽  
Side Chain ◽  
Cellular Functions ◽  
Peptide Substrates ◽  
Triple Mutation ◽  
Alanine Scan ◽  
Lysine Residues ◽  
The Individual

Protein kinase CK1 denotes a family of pleiotropic serine/threonine protein kinases implicated in a variety of cellular functions. Typically, CK1 acts as a ‘phosphate-directed’ kinase whose targeting is primed by a single phosphorylated side chain at position n−3 or n−4 relative to serine/threonine, but increasing evidence is accumulating that CK1 can also engage some of its substrates at sites that do not conform to this canonical consensus. In the present paper, we show that CK1α phosphorylates with the same efficiency phosphopeptides primed by a phosphoserine residue at either n−3 [pS(−3)] or n−4 [pS(−4)] positions. The phosphorylation efficiency of the pS(−4) peptide, and to a lesser extent that of the pS(−3) peptide, is impaired by the triple mutation of the lysine residues in the K229KQK232 stretch to alanine residues, promoting 40-fold and 6-fold increases of Km respectively. In both cases, the individual mutation of Lys232 is as detrimental as the triple mutation. A kinetic alanine-scan analysis with a series of substituted peptide substrates in which the priming phosphoserine residue was effectively replaced by a cluster of four aspartate residues was also consistent with a crucial role of Lys232 in the recognition of the acidic determinant at position n−4. In sharp contrast, the phosphorylation of β-catenin and of a peptide including the non-canonical β-catenin site (Ser45) lacking acidic/phosphorylated determinants upstream is not significantly affected by mutations in the KKQK stretch. These data provide a molecular insight into the structural features that underlie the site specificity of CK1α and disclose the possibility of developing strategies for the preferential targeting of subsets of CK1 substrates.

Gossip, Reputation, and Language

2019 ◽  
pp. 81-99
Author(s):  
Haykaz Mangardich ◽  
Stanka A. Fitneva
Keyword(s):  
Experimental Research ◽  
Speech Acts ◽  
Structural Features ◽  
Reputation Management ◽  
Linguistic Features ◽  
Individual Level ◽  
The Public ◽  
Physical Form ◽  
The Individual

Language is deeply involved in the management of human reputations. In this chapter, we review some of the linguistic features that relate to reputation, drawing extensively on ethnographic and experimental research. At the individual level, what the speaker says, and the physical form of speech contribute to establishing the public face of the speaker. At the interaction level, linguistic devices such as hedges and silences regulate the relations among speakers, expressing politeness, deference, acceptance, or rejection. Finally, linguistic speech acts such as apologies explicitly manipulate the speaker’s and others’ reputations. We also highlight some of the structural features of gossip, which is a genre of conversation that paradigmatically illustrates the role of language in reputation management.

scholarly journals THE POLITICS OF SOCIALIST EDUCATION IN GHANA: THE KWAME NKRUMAH IDEOLOGICAL INSTITUTE, 1961–6

2019 ◽  
Vol 60 (3) ◽  
pp. 407-428 ◽  
Author(s):  
GERARDO SERRA ◽  
FRANK GERITS
Keyword(s):  
Social Sciences ◽  
Political Participation ◽  
Public Discourse ◽  
Kwame Nkrumah ◽  
Education In Ghana ◽  
The Individual ◽  
Changing Role ◽  
Shed Light

ABSTRACTThis article reconstructs the trajectory of the Kwame Nkrumah Ideological Institute (KNII) to shed light on the politics of socialist education in 1960s Ghana. On the basis of archival evidence, it explores the changing role of the institute in the making of Nkrumahism as public discourse and documents the evolving relationship between the universalism of Marxism-Leninism and the quest for more local political iconographies centred on Nkrumah's life and work. Secondly, the article analyses the individual motivations and experiences of a sample of foreign lecturers. The article suggests that ideological institutes offer insights into the processes by which official ideologies were created and disseminated, a foil through which to interrogate the usages and appropriation of social sciences education, and a window onto the multiple ways in which local and foreign agents negotiated their identities and political participation in African socialist experiments.

The role of organizational culture in normalizing paramedic exposure to violence

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Justin Mausz ◽  
Mandy Johnston ◽  
Elizabeth Anne Donnelly
Keyword(s):  
Organizational Culture ◽  
Public Health Problem ◽  
Cultural Norms ◽  
Content Type ◽  
Urban Service ◽  
The Individual ◽  
Constructivist Epistemology ◽  
Inductive Thematic Analysis ◽  
Shed Light

Purpose Violence against paramedics is a complex – but underreported – problem. Extant research suggests organizational culture may play a role in sustaining cultural norms that downplay the significance and limit reporting. The purpose of this paper is to qualitatively explore paramedics’ experience with violence, with particular emphasis on understanding how organizational culture contributes to under-reporting. Design/methodology/approach The authors surveyed paramedics from a single, large, urban service in Ontario, Canada, asking participants to describe their experiences with violence, including whether – and why or why not – the incidents were reported. Within a constructivist epistemology, we used inductive thematic analysis with successive rounds of coding to identify and then define features of organizational culture that limit reporting. Findings A total of 196 (33% of eligible) paramedics completed the survey. Fully 98% of participants disclosed having experienced some form of violence; however, only a minority (40%) reported the incidents to management, or the police (21%). The authors defined a framework within which a lack of support from management, and consequences for offenders, implicitly positions the ability of paramedics to “brush off” violent encounters as an expected professional competency. Disclosing emotional or psychological distress in response to violent encounters invited questions as to whether the individual is personally suited to paramedic work. Originality/value While the extant research has indicated that underreporting is a problem, the findings shed light on why – a critical first step in addressing what has been described as a serious public health problem.

DLK1-DIO3 Region as a Source of Candidate Tumor Suppressor miRNAs in Papil- Lary Thyroid Carcinoma

2020 ◽  
Author(s):  
Leonardo Augusto Marson ◽  
Letícia Ferreira Alves ◽  
Micheli Severo Sielski ◽  
Cristina Pontes Vicente ◽  
Edna Teruko Kimura ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Thyroid Carcinoma ◽  
Genomic Region ◽  
And Migration ◽  
The Individual ◽  
Computational Resources ◽  
The Impact ◽  
Tumor Suppressor Mirnas ◽  
Shed Light

Abstract Background: DLK1-DIO3 genomic region comprises one of the largest microRNA (miRNAs) clusters in human genome. In previous studies we showed the downregulation of several miRNAs from the genomic region in papillary thyroid carcinoma (PTC). Due to the large number of miRNAs within this region the individual contribution of these molecules to PTC development and progression remains unclear. Methods: We used different computational resources to clarify the contribution of DLK1-DIO3-derived miRNAs to PTC. Results: Our analysis suggests that 12 miRNAs from this region cooperate to modulate distinct cancer-relevant biological processes, potentially responding for most of the impact of DLK1-DIO3-derived miRNAs to PTC development and progression. The overexpression of miR-485-5p in two PTC cell lines decreased proliferation and migration, confirming the biological relevance of in silico data. Conclusion: Our results shed light on the role of DLK1-DIO3 region, harboring several tumor suppressor miRNAs in thyroid cancer and open perspectives for the functional exploration of these miRNAs as therapeutic targets for PTC.

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