scholarly journals Thyroid screening in pregnancy

2017 ◽  
Vol 6 (9) ◽  
pp. 3956
Author(s):  
Reena Vijay Wagh ◽  
Mahavir Raghunath Mundra ◽  
Jayshree Jayant Upadhye ◽  
Deepa Baliram Telgote ◽  
Supriya Nivrutti Khillare ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Pregnant Women ◽  
Low Income ◽  
Overt Hypothyroidism ◽  
Antenatal Visit ◽  
Government Medical College ◽  
Routine Test ◽  
Medical College ◽  
Study Results ◽  
Thyroid Profile

Background: Thyroid hormone is critical to normal development of the baby’s brain and nervous system. During the first trimester, the fetus depends on the mother’s supply of thyroid hormone, which comes through the placenta. At around 12 weeks, the baby’s thyroid begins to function on its own. In our study, complete thyroid profile of all antenatal patients was done at the first antenatal visit along with routine investigations. Aim of the study was to study the prevalence of hypothyroidism and hyperthyroidism in low income, urban pregnant women.Methods: This is a retrospective study that includes 400 pregnant women attending the antenatal clinic at Government medical college and hospital, Nagpur in the month of April 2017. These patient’s data was randomly selected in the biochemistry department where samples come. Thyroid profile is being done as a routine test along with other antenatal profile tests in our hospital. Thyroid profile test includes serum T3, serum T4 and serum TSH.Results: A total of 400 pregnant women were included in this study. Results showed 34% prevalence of hypothyroidism of which 30% being subclinical hypothyroidism and 4% overt hypothyroidism. There was 9.5% prevalence of hyperthyroidism of which 5.5% being subclinical hyperthyroidism and 4% overt hyperthyroidism.Conclusions: The study shows a very high prevalence rate of hypothyroidism in the patients attending the antenatal outpatient department at Government medical college and hospital, Nagpur. This justifies the inclusion of thyroid profile test as a routine test in the antenatal profile.

scholarly journals Effect of high blood pressure on thyroid and lipid profile of pregnant women

2019 ◽  
Vol 8 (9) ◽  
pp. 3699
Author(s):  
Gurpreet Kaur Gill ◽  
Mandeep Kaur ◽  
Partapbir Singh ◽  
Juhi Kataria
Keyword(s):  
Blood Pressure ◽  
Thyroid Hormone ◽  
Pregnant Women ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Medical Problem ◽  
Maternity Hospital ◽  
Thyroid Stimulating Hormone ◽  
Urine Albumin ◽  
Thyroid Profile

Background: Hypertension is common medical problem encountered during pregnancy, complicating up to 10% pregnancies. Hypertension is defined as the systolic blood pressure ≤140 mmHg and a diastolic blood pressure ≥90 mmHg on two separate measurements at least 4-6 hours apart. During pregnancy thyroid demand changes with increased iodine uptake and synthesis of thyroid hormone. Serum from pre-eclamptic women had both a higher ratio of free fatty acid to albumin and increase up take of free fatty acids, which are further esterified to triglyceride. The aim of the present study was to evaluate thyroid hormone, lipid profile and urine albumin in hypertensive pregnant women and its comparison with normotensive pregnant womenMethods: Total 90 samples were collected from Beri Maternity Hospital and Civil Hospital, Amritsar. Blood samples were analysed for biochemical parameters viz. lipid profile and thyroid profile. Urine samples were also analysed for presence of albumin.Results: From the study it has been revealed that thyroid stimulating hormone (TSH) levels increased in hypertensive pregnant women mean (4.26±1.1µ/ml). The total cholesterol (234.56±14.2mg/dl), triglyceride (138±16.96mg/dl), HDL (50.7±7.4mg/dl), LDL (156.2±17.11mg/dl) and VLDL (27.7±3mg/dl) was found altered in hypertensive pregnancy as compared to normotensive pregnancy. The albumin excretion was seen in 13.3% hypertensive pregnancies.Conclusions: TSH were elevated in hypertensive pregnant women due to the effects of estrogen. Among all the parameters of lipid profile, total cholesterol, TG, LDL and VLDL has been increased significantly in hypertensive pregnant women as compared to normotensive pregnant women due endothelial dysfunction. 

scholarly journals Prevalence of Asymptomatic Bacteriuria in Antenatal Women Coming to NRIMC&GH

2016 ◽  
Vol 30 (1) ◽  
pp. 30-36 ◽  
Author(s):  
K Ramalingam ◽  
Vijaya Madhuri Surasani ◽  
Mounica Bollu
Keyword(s):  
Pregnant Women ◽  
Susceptibility Testing ◽  
Asymptomatic Bacteriuria ◽  
Antenatal Visit ◽  
Study Group ◽  
Medical College ◽  
Number Of Microorganisms ◽  
Loin Pain ◽  
To Come ◽  
High Degree

Objective(s):The aim of the study was to determine the prevalence of asymptomatic bacteriuria in pregnant women attending the antenatal OPD and to treat them. Also to identify the organisms causing asymptomatic bacteriuria and the risk factors in pregnant women.Materials and Methods: The present observational study was conducted in the Department of Obstetrics, NRI Medical College, Chinakakani, Mangalagiri from Aug-2012 to Aug-2014. Material for the study consisted of 100 urine samples obtained from asymptomatic 100 pregnant women in their first antenatal visit. The study group consisted of cases from in and around Mangalagiri, attending antenatal OPD, NRI Medical College, Chinakakani. Each patient was first asked whether she had any symptom of urinary tract infection such as dysuria, urgency, haematuria, loin pain and fever. After ascertaining that she was asymptomatic, preliminary data on maternal age, gravidity, parity and period of gestation were collected on a predesigned proforma. Detailed history about previous antenatal check-up, hypertension were also taken. A clean-catch midstream urine sample was collected and MacConkey agar, Blood agar plates were used for culture .Bacterial counts were done to determine the number of microorganisms per millilitre.Antimicrobial susceptibility testing was done for the isolates by the Kirby-Bauer method (disc diffusion).Results: The prevalence of asymptomatic bacteriuria in the study group was 15%.Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus saprophyticus, Staphylococcus aureus were the isolates in the study group. Isolates showed maximum susceptibility to gentamycin followed by cefotaxime, nitrofurantoin and cotrimoxazole. They showed high degree of resistance to cephalexin and ceftriaxone. All the asymptomatic pregnant women with significant bacteriuria were treated and asked to come back after 7-10 days for repeat culture and susceptibility testing, which was done as a part of follow-up.Conclusion: Increasing gestational period showed increase in the incidence of asymptomatic bacteriuria and also increased incidence was seen in the pregnants with anaemia. Routine antenatal screening for asymptomatic bacteriuria should be implemented and treatment of those showing bacteriuria must be practiced to prevent adverse perinatal outcome. Untreated asymptomatic bacteriuria progresses to pyelonephritis (13-27%). Therefore, routine screening for bacteriuria is recommended during pregnancy.Bangladesh J Obstet Gynaecol, 2015; Vol. 30(1) : 30-36

scholarly journals Prevalence and complications of Hypothyroidism during pregnancy in western Nepal

2014 ◽  
Vol 3 (1) ◽  
pp. 48-50 ◽  
Author(s):  
TL Upadhyaya ◽  
A KC ◽  
S Paudel
Keyword(s):  
Thyroid Function ◽  
Care Center ◽  
Tertiary Care ◽  
College Teaching ◽  
Thyroid Function Test ◽  
Overt Hypothyroidism ◽  
Medical College ◽  
Study Results ◽  
Function Test ◽  
Entire Pregnancy

Background: This study was designed to know the prevalence of hypothyroidism during pregnancy in western part of Nepal and its potential complications. Methods: One Hundred seven pregnant cases from Gandaki Medical college teaching hospital and Diabetes thyroid and Endocrinology care center, two of the tertiary care centers in Pokhara were enrolled in the study from the year 2011 January to 2012 December. Detailed history and physical examination was done. Thyroid Function test (FT3, FT4 andTSH) were performed after the confirmation of pregnancy. Patients were followed up during entire pregnancy. Seven patients dropped out from the study. Results: Out of 107 patients 56 patients had TSH below 6 mIU/L,31patients had TSH between 6mIU/L - 10 mIU/L and 13 patients had TSH more than 10 mIU/L. Seven patients dropped out from the study. There was1 miscarriage, 1 still birth from hypothyroid mother and 11 hypothyroid and subclinical hypothyroid mothers had preterm delivery. Conclusion: Prevalence of overt hypothyroidism is around 13% and subclinical hypothyroidism is around 31% in pregnant ladies in western Nepal. Also complications like stillbirth should be prevented by detecting and treating hypothyroidism early. So we recommend all patients with pregnancy to perform thyroid function test at the start of pregnancy. Nepal Journal of Medical Sciences | Volume 03 | Number 01 | January-June 2014 | Page 48-50 DOI: http://dx.doi.org/10.3126/njms.v3i1.10358

scholarly journals Prevalence of hypothyroidism amongst pregnant women: a study done in rural set up

2018 ◽  
Vol 7 (4) ◽  
pp. 1586 ◽  
Author(s):  
Nancy S. Pillai ◽  
Jemela Bennet
Keyword(s):  
Thyroid Hormone ◽  
Pregnant Women ◽  
Intellectual Development ◽  
Thyroid Dysfunction ◽  
First Trimester ◽  
Reproductive Age ◽  
Overt Hypothyroidism ◽  
Endocrine Disorders ◽  
Thyroid Disorder ◽  
In Pregnancy

Background: Thyroid disorders are the commonest endocrine disorders affecting women of reproductive age group. The most frequent thyroid disorder in pregnancy is maternal hypothyroidism. During early pregnancy the foetus is totally dependent on maternal thyroid hormone supply. Thyroid hormone is critical for foetal brain and intellectual development and some preventable conditions like abruption, pre-eclampsia etc. which produce morbidity and pose special risk for pregnancy and the developing foetus.Methods: All subjects enrolled in the study as per the inclusion criteria will be subjected to a detailed history and clinical examination using a predesigned proforma. A serum TSH value will be sent in 1st trimester between 6-10 weeks period of gestation for all pregnant women.Results: The prevalence of thyroid dysfunction in pregnancy was 10.8% with hypothyroidism being 9.2%, out of which 8.5% were cases of subclinical hypothyroidism and 0.7% were cases of overt hypothyroidism. On assessing the risk factors for developing thyroid dysfunction in pregnancy, increases in incidence were seen with maternal age and increasing BMI, both of which were statistically significant.Conclusions: This study showed an increased prevalence of hypothyroidism in pregnancy recommending a need for universal screening for all pregnant women in the first trimester itself. This study aims at validating the efficacy of the above-mentioned screening.

scholarly journals A prospective clinical trial to evaluate the prevalence of thyroid disorder among pregnant women and obstetrical and fetal outcome in a tertiary health centre located in central India

2020 ◽  
Vol 9 (8) ◽  
pp. 3393
Author(s):  
Manjari G. Jain ◽  
Neeraj K. Jain ◽  
Mita Mazumdar
Keyword(s):  
Clinical Trial ◽  
Pregnant Women ◽  
Health Centre ◽  
First Trimester ◽  
Fetal Outcome ◽  
Prospective Clinical Trial ◽  
Research Centre ◽  
Overt Hypothyroidism ◽  
Thyroid Disorder ◽  
Medical College

Background: A prospective clinical trial to evaluate the prevalence of thyroid disorder among pregnant women and obstetrical and fetal outcome was done in a tertiary health centre (RKDF Medical College and Research Centre, Bhopal) located in central India.Methods: This prospective study was carried out in antenatal women in their first trimester attending antenatal OPD in RKDF Medical College and Research Centre, Bhopal, Madhya Pradesh to know the prevalence of thyroid disorder and its association with pregnancy outcome.Results: In this study prevalence of thyroid disorder was 12.4%, subclinical hypothyroidism 7.2%, overt hypothyroidism 3.4%, subclinical hyperthyroidism 1.4%, overt hyperthyroidism 0.4%. Thyroid disorder is responsible for several obstetrical and fetal complication like pre-eclampsia, preterm delivery, abortion, IUGR and low birth weight.Conclusions: Thyroid disorder associated with poor obstetrical outcome and fetal complication. so timely diagnosis and treatment is required. Universal screening should be preferred over high-risk screening because of high prevalence of the disease in India.

scholarly journals Health Education Needs of First Visit Pregnant Women in Antenatal Clinics in Khayelitsha, South Africa

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Thabani Noncungu ◽  
Jennifer Chipps
Keyword(s):  
South Africa ◽  
Health Education ◽  
Pregnant Women ◽  
Health Information ◽  
Low Income ◽  
Information Needs ◽  
Antenatal Visit ◽  
Antenatal Clinics ◽  
Education Needs ◽  
Antenatal Visits

Health education is a key component of first antenatal visits. The aim of this study was to describe the health education needs of pregnant women on their first visit to antenatal clinics in Khayelitsha, South Africa. A quantitative descriptive survey was conducted, to investigate the lifestyle, pregnancy-related, psycho-social health education needs and predictors of health education needs during pregnant women’s first antenatal clinic visit. The research was conducted at two purposively selected antenatal clinics in Khayelitsha, a low-income suburb in Cape Town, South Africa. The respondents were considered eligible for the study if they were Xhosa speaking, pregnant, older than 18 years, making a first visit to antenatal care, and able to complete their consent form or provide consent from parents or relatives. Respondents were eligible for the study regardless of the number of pregnancies they had previously had, their age and previous medical conditions. There were a total of 240 (92%) respondents. Overall pregnancy-related health education needs were rated the highest (m=4.0, [95%CI3.95–4.09]), with information on how the baby grows and develops during pregnancy (m=4.6, [95%CI4.5–4.7]) the highest. The lowest rated health information needs were testing for HIV and prevention thereof (m=3.5, [95%CI3.3–3.7]) and how to use seat belts during pregnancy (m=3.2, [95%CI3.0–3.4]). A lack of awareness of the duration of pregnancy predicted significantly higher overall health education needs and lifestyle education needs. The study recommends that pregnant women should be provided with prioritised health information during their first antenatal visit, especially given the high risk of late bookings for first antenatal visits.

scholarly journals Study of Thyroid Function in Patients of Srikakulam, Andhra Pradesh, Who Were Suffering from Various Depressive Disorders

2021 ◽  
Vol 10 (35) ◽  
pp. 2980-2984
Author(s):  
Silla Vijaya Bhaskara Gupta ◽  
M. Padma Geetanjali ◽  
Ladi Bharati Kumari Devi
Keyword(s):  
Depressive Disorder ◽  
Thyroid Function ◽  
Andhra Pradesh ◽  
Depressive Disorders ◽  
Overt Hypothyroidism ◽  
Government Medical College ◽  
Medical College ◽  
Rural And Urban ◽  
Thyroid Hormone Levels ◽  
Serum Tsh

BACKGROUND Thyroid disorder patients are more prone to develop depressive symptoms. Depression is also associated with various thyroid abnormalities.1 Slight change in thyroid hormone levels show symptoms of depression, anxiety, increasing fatigability and psychomotor slowing. The depressive symptoms are more in elderly patients with rapid changes in thyroid hormone levels.1 In depressive disorder patients, 1 % to 4 % have primary (Overt Hypothyroidism) and 4 % to 40 % have subclinical Hypothyroidism.2 Overt thyroid dysfunction is usually mild. Thyroid abnormality is not a causal factor, it is mainly a risk factor for depression.2 We intended to study the thyroid function in various depressive disorder patients of Srikakulam district at Government medical college & General hospital Srikakulam. Srikakulam district has been chosen for this study for its backwardness in the residuary state of Andhra Pradesh. The objectives were to find out thyroid function levels like serum TSH, T3 and T4 in various depressive disorder patients and compare with the severity of clinical score, analyse and correlate with various depressive disorder patients of different age and sex groups, locality (both rural and urban areas). METHODS This observational study of thyroid function was conducted among 61 various depressive disorder patients of both males and females of 21 to 60 years age group who attended OPD and IPD of Psychiatry, Government medical college and general hospital, Srikakulam. We analysed and correlated serum TSH, T3 & T4 levels with various depressive disorders. RESULTS It was observed that subclinical hypothyroidism had a clinical severity of 16.39 %, overt hypothyroidism was 1.63 %, secondary hyperthyroidism was 1.63 % and euthyroidism was 80.33 % of various depressive disorders and was more common in females than in males and equal in distribution in both the rural and urban population. CONCLUSIONS Hypothyroidism was found to have been associated with various depressive disorders, cognitive function and psychosis among female patients and hyperthyroidism was associated with psychosis, anxiety, depression and cognitive impairment. KEY WORDS Depression, Hypothyroidism, Hyperthyroidism, Euthyroidism

scholarly journals An observational study to assess obstetric services trends among pregnant women registered at a health centre of Chandigarh city

2018 ◽  
Vol 5 (12) ◽  
pp. 5290
Author(s):  
Munish Kumar Sharma ◽  
Neeraj Gour ◽  
Meenal Thakare ◽  
N. K. Goel ◽  
Meenakshi Chaudhary
Keyword(s):  
Pregnant Women ◽  
Rainy Season ◽  
Health Centre ◽  
Careful Analysis ◽  
Healthcare Services ◽  
Summer Season ◽  
Government Medical College ◽  
Medical College ◽  
Field Practice ◽  
Year 2013

Background: Maternal and child healthcare services are very important for the health outcomes of the mother and that of the child by ensuring that both maternal and child deaths are prevented. Present study has been planned to study the trend of utilization of antenatal care services among women registered at field practice area of Government Medical College & Hospital, Chandigarh.Methods: Secondary data of pregnant women registered at field practice area of Government Medical College & Hospital, Chandigarh has been collected from records of respective health set up. Data has been analyzed to find out trend of different ANC service indicators like year of registration, season of registration, TT immunization, Parity, his risk behavior of pregnancy, JSY registration, MTP (medical termination of pregnancy), hemoglobin level etc.Results: Out of all registration trend of registration of new pregnancy was almost similar during all four years (2013-2017). Although after careful analysis of data it more in rainy season (10.1%) in year 2013-14 whereas summer season reported more new pregnancies (10.4%) in the year 2016-17. out of total doses received of TT 1st dose among all reported pregnant women majority of doses (11.9%) received in summer season of year 2016-17 followed by 9.2% in rainy season of year 2013-14. Number of registration of pregnant women was almost equal among all years of registration.Conclusions: It provides future direction to conduct more such studies to find out trend considering some public health related correlates. Simultaneously it also urges researchers to find out reasons of such trends in a bid to make results more applicable.

scholarly journals Prevalence of Abnormal Glucose Tolerance in Obese Pregnant Women - A Study from a Tertiary Care Centre

2021 ◽  
Vol 10 (44) ◽  
pp. 3769-3774
Author(s):  
Ann Mary George ◽  
Ajay Kumar
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Pregnant Women ◽  
Oral Glucose ◽  
Government Medical College ◽  
Abnormal Glucose Tolerance ◽  
Family History Of Diabetes ◽  
Medical College ◽  
History Of

BACKGROUND Obesity has emerged as an important risk factor in modern obstetrics and poses a major threat to pregnancy by causing complications including gestational diabetes. It also increases the risk of cardiovascular diseases and diabetes mellitus in later life. Obesity creates major technical challenges in providing maternity services too. The objective of the study was to assess the prevalence of abnormal glucose tolerance in obese pregnant women in a Government Medical College over one year. METHODS A prospective observational study was conducted among obese pregnant women, registered at the Outpatient department of Obstetrics and Gynaecology at the Government Medical College, Kottayam from January 2017 to December 2017. 450 women were considered for the study after satisfying inclusion and exclusion criteria. BMI was calculated using pre-pregnant weight. An oral glucose test was performed with 75 gm glucose at 24 to 28 weeks of pregnancy after 8 hours of fasting. International Association of Diabetes and Pregnancy Study Group cut-offs i.e., fasting blood sugar values more than 92 mg/dl, 1hr value more than 180 mg/dl, 2 hr value more than 153 mg/dl were used as the criteria. Oral glucose tolerance was considered abnormal if any of the above values were impaired. RESULTS The prevalence of abnormal glucose tolerance among the 450 pregnant women was 35.6 %. The incidence of abnormal GTT increased with increasing age and in those with a history of menstrual irregularities and infertility treatment. No relation was found between economic status, family history of diabetes, preeclampsia and abnormal GTT. CONCLUSIONS Obesity turns to be a menace in the reproductive life of women that begins by affecting the fertility, continues to cause complications in pregnancy, increases morbidity in the long-term future and reduces the quality of life. Since more than one-third of the study population was affected by gestational diabetes, active intervention to reduce the weight preconceptionally is needed. KEY WORDS Obesity, Glucose Tolerance Test, Gestational Diabetes Mellitus, Body Mass Index, Pregnancy

scholarly journals Asymptomatic Bacteriuria among Pregnant women in Addis Ababa, Ethiopia: Prevalence, Causal agents, and their Antimicrobial Susceptibility

2020 ◽  
Author(s):  
Ketema Bizuwork ◽  
Haile Alemayehu ◽  
Girmay Medhin ◽  
Wondwossen Amogne ◽  
Tadesse Eguale
Keyword(s):  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Low Income ◽  
Addis Ababa ◽  
Bacterial Species ◽  
Asymptomatic Bacteriuria ◽  
Low Income Countries ◽  
Diffusion Method ◽  
Antenatal Visit ◽  
E Coli

Abstract BackgroundAsymptomatic bacteriuria (ASBU) is an important health problem among pregnant women particularly in low income countries. This study aimed to estimate prevalence of ASBU, to identify causal bacterial pathogens and their antimicrobial susceptibility among pregnant women attending antenatal care centers in Addis Ababa, Ethiopia. MethodsHealth facility based cross-sectional study was conducted from March to May, 2019, where 281 pregnant women with no symptom of urinary tract infection were examined using standard microbiological techniques. Women whose urine sample carried greater than or equal to 105 colony forming unit (CFU) of bacteria per milliliter was considered to have ASBU. Antimicrobial susceptibility of isolates was investigated using Kirby-Bauer disk diffusion method on Muller-Hinton agar plates.Results Out of 281 pregnant women examined, 44 (15.7%) had ASBU and none of the factors tested in the current analysis were significantly associated with occurrence of ASBU (p < 0.05). The most frequently isolated bacterial species were Escherichia coli 17(30.2%), Proteus, 13(23.2%) and Entrococcus 11(19.6%). All of the E. coli, Citrobacter and Klebsiela isolates and 84.6% of Proteus species were resistant to ampicillin. All bacterial isolates were resistant to at least one of antimicrobial agents tested. Resistance to three or more antimicrobials was detected in 15 (88.2%) of E. coli, 10 (76.9%) of Proteus, and 6 (54.6%) of Entrococcus isolates. Resistance to as high as 7 antimicrobials among E. coli and Proteus isolates and 9 antimicrobials among Entercoccus isolates was detected.ConclusionsRoutine screening for ASBU during antenatal visit is likely to result in early treatment and minimize complication to the mother and fetus. Assess sensitivity of isolates to commonly prescribed antimicrobials rather than treating empirically is recommended.

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