scholarly journals Evaluation of clinicopathological profile of subjects with intrauterine fetal death

Author(s):  
Sunil Kumar Pandey ◽  
Surabhi Porwal

Background: Intrauterine foetal death is an immense emotional burden for everyone concerned specially in the last trimester. Therefore, it is very important to find out, what has happened. Evaluation of clinical and pathological profile of women presenting with intrauterine foetal death has evoked great interest among the obstetricians.Methods: The prospective observational study was conducted in the department of Obstetrics and Gynaecology N.S.C.B. Medical College Jabalpur during 1st June 2012 to 31st October 2013. A total of 155 intrauterine foetal death subjects admitted during this period were evaluated. Clinically and laboratory profile of subjects done.  Histomorphology of placenta was performed in each case. Full HPR finding were then correlated with clinical and laboratory findings of subjects.  Results: Poor vascularity of villi and fever were significantly associated (p<0.01). Hypertension and Convulsion and fibrinoid necrosis, syncytial knot and placental infarcts were significantly associated (p<0.001) Premature placenta is associated with cytotrophoblastic layer (p<0.01). Conversely post mature placenta is associated with calcification and infarction.  (p<0.01).  Conclusions: All placentae associated with foetal death have either gross or microscopic abnormalities. Present study is a step towards understanding and extrapolating the already known causes of intrauterine foetal death in the perspective of Jabalpur and its adjoining districts.

2022 ◽  
Vol 19 (1) ◽  
pp. 89-91
Author(s):  
Kamar Jahan ◽  
Binod Kumar Mahaseth

Introduction: Foetal death at any stage of pregnancy is not just a tragic event but also a more traumatic for the mental well-being of a mother. It is one of the most wrenching events in the field of obstetrics. Aims: The study was done to determine the probable risk factors of intrauterine foetal death and role of antenatal care in its prevention. Methods: The study was conducted  in Obstetrics and Gynecology department at Nepalgunj Medical college from July 2018 to July 2020 .Inclusion criteria were  intrauterine fetal death  of >28 weeks of gestation and baby weighing  1000 grams or more . An exclusion criterion was molar pregnancy. Results: There were 115(3.52%) intrauterine fetal death during the study period, making it 35 per 1000 cases. In 17(14.78%) the cause of intrauterine fetal death was not known. The other common associated risk factors were prematurity in 14(12.17%) and hypertension in 13(11.30%). Similarly anemia and antepartum hemorrhage were seen in 13(11.30%) each. 11(9.56%) patients had oligohydramnios. Mal presentation was found in 8(6.95%) patients while polyhydromnios in 6(5.21%).The commonest age range in whom intrauterine fetal death was seen was 20-30 (73.90%). 28 (24.34%) patients were at preterm pregnancy ranging between 28-30 weeks whereas 17(14.78) intrauterine fetal death occured at  32-34 weeks. 77 foetuses were preterm and their birth weight was between 1 - 1.5 kg  with the mean wt of  1175.73 gms. Conclusion: Intrauterine fetal death is still common inspite of the improving awareness in importance of regular antenatal care. In majority, the cause of intrauterine fetal death is still unknown. However, where the cause was known prematurity was the commonest.


Author(s):  
Anubha Manu Prasad ◽  
. Manju Agrawal ◽  
Ankit Laddha

Background: The objective of the present study was to examine the etiological factors, both maternal and fetal, that caused IUFD. Methods: It was a hospital based prospective observational study conducted in the Department of Obstetrics and Gynaecology at Jhalawar Medical College from January 2020 to December 2020. 120 cases of IUFD of ?24 weeks of gestation or foetuses weighing ?500 gramswere included in the study. Results: The incidence of IUFD was 37.8/1000 total birth. IUFD occurredmainly in 25-35yrs age group (55%), unbooked cases (70%),multigravida (59.2%), preterm (<37 weeks of gestation). The risk factors were PIH (49.2%), infections (9.2%), hypothyroidism (5%), Rh negative with hydrops fetalis (5%),GDM (4.2%), chronic hypertension (2.5%), previous H/O LBW (2.5%), H/O prior stillbirth (5%), hyperthyroidism (1.7%), oligohydramnios (46.7%), APH (20.8%) and congenital fetal anomalies (19.2%). Conclusion: IUFD rate still remains high. Therefore, regular ANC check up and early identification of risk factors like PIH, anaemia, infections, genetic counselling and timely referral to well equipped centre may help prevent IUFD and maternal mortality and morbidity. Keywords: IUFD, ANC, Preterm


2020 ◽  
pp. 60-62
Author(s):  
Narendra Nath Hait ◽  
Brahmarshi Das ◽  
Ratan Chandra Mandal ◽  
Haricharan Roy ◽  
Debarshi Jana

Background: Threatened abortion is till most common cause of early trimester bleeding PV and can be diagnosed and managed by early USG diagnosis. Materials and methods: This was a prospective observational study. Place of the study was Department of Obstetrics and Gynaecology and Department of Radiodiagnosis, Midnapore Medical College and Hospital from January 2019 to June 2020. Eighteen months. Result: When the clinical method to diagnose threatened miscarriage was compared to the sonographic method, it was evident that sonographic method was reliable than the clinical method and the difference was statistically significant. Conclusion: In case of missed miscarriage and complete miscarriage, although the percentage of discrepancy was 100%, on further statistical analysis, the discrepancy was not statistically significant. And the cause behind this was probably inadequate sampling.


2017 ◽  
Vol 8 (1) ◽  
pp. 50-54
Author(s):  
Sharmin Abbasi ◽  
Sehereen Farhad Siddiqua ◽  
Mohammad Noor A Alam ◽  
Suha Jesmin ◽  
Md Mahmudur Rahman Siddiqui ◽  
...  

Background: Intrauterine fetal death is means- intrapartum death after the fetus has reached the age of viability8. As in IUFD journey, labor pain will be fruitless. So, it is of utmost importance to search for the method which can reduce hours of pain in labor of IUFD cases.Metarials Methods: In this research work patients divided in two groups. Induction of labour in one group was given by combination of mifepristone and misoprostol other group by misoprostol only and we try to find out the best method. To compare the effectiveness, induction to delivery interval, safety and side effects of combination of mifepristone and misoprostol versus conventional use of misoprostol alone in induction of labour in patients with intrauterine fetal death. It is a Prospective randomized comparative study in Anwer Khan Modern Medical College Hospital and Dhaka Medical College Hospital among 70 patients with IUFD after 28 weeks of gestation during January 2014- January 2016.Result: We allowed the patients up to third gravid and after 28 weeks of gestation. Patients were grouped as Group A(35) & Group B (35). In Group A Induction was given by single oral dose of 200 mg mifepristone, and after 48 hours, tab. Misoprostol in post. fornix started if <34 weeks-100 ?gm dose and >34 weeks-50 ?gm dose. Doses were repeated every 6 hourly intervals if required. In Group B Induction was given by 100 ?gm misoprostol at 6 hourly interval in post. Fornix. In both groups we allowed misoprostol maximum 600 ?gm. Oxytocin was given for augmentation if needed. The two study groups did not differ demographically. Induction to delivery time was shorter with combined regimen group (P<0.001). Induction to delivery interval ranges from 10-12 hours in mifepristone plus misoprostole group.In only misoprostol group it was about 24-26 hours. Doses of misoprostol was lower in combined group (P<0.001). 4 patients need Oxytocin for augmentation in only misoprostol group. In combined group oxytocin was not needed. The two groups did not differ as regards complications experienced during labour and delivery significantly. In overall out come 2 failed induction in misoprostol only group but not in combinedgroup.Conclusion: In Induction of IUFD mifepriston plus misoprostol is an effective combined group. It is safe, non invasive, easily tolerable, highly cost effective, had less induction to delivery interval, required less dose of misoprostol and no need of augmentation with oxytocin. So,the combined group is more effective than conventional regimen of misoprostol alone.Anwer Khan Modern Medical College Journal Vol. 8, No. 1: Jan 2017, P 50-54


2017 ◽  
Vol 45 (3) ◽  
pp. 131-133 ◽  
Author(s):  
Lipy Bakshi ◽  
Samira Hoque ◽  
Farhana Tanjin ◽  
Sukla Dey ◽  
Mithun Bakshi

Intrauterine fetal death (IUFD) and still births is a tragic event for the parents and an important cause of perinatal mortality. This retrospective study study was conducted in the department of Obstetrics and Gynecology of Dhaka National Medical College Hospital from January 2015 to June 2016 with the intention to understand the incidence, socio-epidemiological and etiological factors of intrauterine fetal death (IUFD). A total of 1838 pregnancies were studied retrospectively during the study period & out of them 48 were IUFDs. Ante partum and intra partum events leading to fetal demise were recorded, socio-demographic and clinical characters were noted. there were 1838 deliveries . The incidence of prenatal loss was 26 per 1000 live births. Despite advances in diagnostic and therapeutic modalities the rate of IUD is unacceptably high. Socio-cultural background, lack of adequate antenatal care and inaccessible health care are some of the reasons that predispose women to IUFD. Majority of fetal wastage can be prevented with universal and improved antenatal care.Bangladesh Med J. 2016 Sep; 45 (3): 131-133


Author(s):  
Kajal Patra ◽  
Shibram Chattopadhyay ◽  
Poulami Samanta ◽  
Chandrakanta Mondal

Background: Intrauterine fetal death(IUFD) is an unhappy reality, a lamentable incidence for both the family and the caregiver. It is an important indicator of both maternal and perinatal health in a population. The study of fetal death is crucial in promoting actions for maternal and child health. Aim of this study was to determine the incidence, indications and maternal morbidity and maternal mortality associated with caesarean section in patients with IUFD and to establish the place of caesarean section in present day scenario.Methods: The study was a retrospective analysis of all caesarean section carried out in a case of IUFD in last 5 years (2013-2017). The indications, incidence, maternal morbidity, mortality was studied well in this time period in a rural medical college of West Bengal.Results: Total 108425 deliveries occurred in the hospital in last 5 years, out of which 31800 were caesarean section. 56 cases were done in case of diagnosed IUFD. There was 2489 number of IUFDs in the given period. The incidence of IUFD was 22.96 per 1000 deliveries. Induction was done in 2489 cases; 56 cases underwent caesarean section (2.25%) and rest was delivered vaginally.Conclusions: Early diagnosis, early referral and proper antenatal checkup can reduce the chances of IUFD and number of caesarean deliveries in IUFD. The role of cesarean deliveries in previous caesarean deliveries having IUFDs has been emphasized.


2016 ◽  
Vol 30 (1) ◽  
pp. 15-19
Author(s):  
Arifa Akter Zahan ◽  
Kh Shahnewaz ◽  
Fahmida Khan ◽  
Ummay Salma

Objective(s): The aim of the study wasto evaluate the safety and feasibility of non-descent vaginal hysterectomy in advancing gynaecological practice.Materials and methods: This prospective observational study was conducted from 1st July 2013 to 31st June 2014 in Obstetrics and Gynaecology Department of Kumudini Women’s Medical College & Hospital, Mirzapur, Tangail. Fifty patients who needed hysterectomy for benign gynaecological disorders and who had no descent of uterus or vagina were the target population for this study. Main outcome measures were i) difficulty of operation, ii) procedures for overcoming the difficulties,iii) switch over to abdominal route, iv) time taken to complete the operation, v) blood loss during operation vi) need of blood transfusion and vii) postsurgical hospital stay.Results: In all (100%) cases vaginal hysterectomy was completed successfully. Commonest age group (46%) was between 41-45 years. All patients were parous. Size of the uterus was less then 8 wks in 21 cases, 8wks to 12 wks in 27 cases and more than 12 wks in 02 cases. Commonest indication was dysfunctional uterine bleeding (DUB) (44%). Mean duration of surgery was 50.5 ± 5.46 minutes. Mean blood loss was 100± 22.43 ml.Blood transfusion was required in four cases. Average duration of hospital stay was 3.1± 1.2 days. Complications were minimum which included, bladder injury, UTI and Vault infection.Conclusions: In properly selected cases non-descent vaginal hysterectomy is safe, feasible and patient friendly.Bangladesh J Obstet Gynaecol, 2015; Vol. 30(1) : 15-19


2020 ◽  
Vol 28 (1) ◽  
pp. 90-93
Author(s):  
Mahenaz Afroz ◽  
Begum Rokeya Anwar ◽  
Afroza Khanom ◽  
Prodip Kumar Biswas ◽  
Sadia Islam ◽  
...  

Intra uterine fetal death occur in 1% of pregnancy. The patient goes into labour in most of the cases, spontaneously. Retained dead fetus may cause disseminated intravascular coagulation sometimes resulting death of a mother. Objective: The aim was to find out the reults after using intravaginal Misoprostol in Intrauterine fetal death in last trimester of pregnancy. Study design: This was a cross sectional observational study prospective in nature on 160 cases of intra uterine fetal death patients in indoor of department of Gynae and Obstertrics of Sir Salimullah medical college Hospital, Dhaka from 02/01/13 to 01/07/13, for a period of 6 months. Result: 60% of the patients were primi gravida. Mean age of the patients was 22.12±4.3 years 44% were in 33 to 36 weeks of pregnancy when induction was done. 41 (82%) patients having Bishops score d” 6 reqired 21±8.25 hours where as 09 (18%) patients having Bishops score e” 6 needed 10±1,1 hours to complete the delivery. There were no reports of maternal mortality. All the patients delivered per vaginally except one (2%) who needed ceasearean section due to development of chorioamnionitis. Conclusion: Intravaginal misoprostol can aid in vaginal delivery safely. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 90-93


2020 ◽  
pp. 64-67
Author(s):  
Shilpa. R ◽  
Vishnu N Haygreev ◽  
Sreenivasa Chowdary. J

Dengue fever is an arthropod borne viral fever. It is acquiring epidemic proportion in this part of the world and it has become major public health problem with high mortality. Earlier it was prevalent in those areas with humid atmosphere and plenty of rain, with changing monsoon pattern this disease is becoming prevalent in deccan land scape including Karnataka. It is vital to recognize at the earliest the signs and symptoms, alteration in biochemical parameters and multisystem involvement pattern in dengue to treat effectively. This study is undertaken to evaluate common modes of clinical presentation and complications of dengue in our hospital and to correlate these features with laboratory findings which may help us in early diagnosis and better case management. Out of total 100 cases studied 65 were classified as classical dengue fever, 20 as DHF and 15 as DSS


Author(s):  
Dr. Subhashree Sethi ◽  
Dr. Sushmita Prasad

Acute viral hepatitis is the commonest cause of jaundice in pregnant women with clinical evidence of hepatitis with HEV being the predominant cause. Acute viral hepatitis is a systemic infection caused by six distinct types of viruses A, B, C, D, E and G. The present study was a prospective observational study done in the Department of Obstetrics and Gynaecology, Patna Medical College & Hospital, Patna over a 2 years period with 100 pregnant patients suffering from acute viral hepatitis. This study was conducted to know the prevalence, obstetric complications and maternal, perinatal outcome in pregnant women presenting with acute viral hepatitis. In our setup most common cause of acute viral hepatitis with adverse fetomaternal outcome was found to be with Hepatitis E .HBV was found to be the 2rd most common etiological factor followed by HAV. Adverse fetomaternal outcome like abortion, preterm, LBW, IUGR, IUD, higher NICU admissions, coagulation derangement, PPH, hepatic encephalopathy were mostly associated with HEV infection. Acute viral hepatitis was associated with a maternal mortality of 17% mostly attributable to HEV infection. In a developing country like India, awareness of pregnant women about viral hepatitis, regular ANC care, cost effectiveness and easy accessibility to health care system and treatment plays a key role in improving the current situation. Keywords:  Viral hepatitis, Maternal, Fetal, Pregnancy


Sign in / Sign up

Export Citation Format

Share Document