scholarly journals Correlation of clinical, biochemical and radiological characteristics with histopathology of ovarian masses: hospital based descriptive study

Author(s):  
Poonam Laul ◽  
Urvashi Miglani ◽  
Atima Srivastava ◽  
Neelam Sood ◽  
Sanjeev Miglani

Background: Ovarian cancer is an important cause of morbidity and mortality in the middle aged women. A systematic study of all ovarian tumours encountered in a large institute over a period of years is more likely to produce a significant amount of useful data regarding the clinical manifestations, the incidence of various types of ovarian tumours and the type of treatment offered. In this study we correlate various clinical presentations, ultrasound features, and various tumour marker levels with histopathology of ovarian masses.Methods: The study was conducted in the department of obstetrics and gynaecology in collaboration with department of radiology and pathology and lab medicine, Deen Dayal Upadhyay hospital from April 2015 to December 2016.Results: In the present study, 97 ovarian masses have been operated out of total 708 gynaecological surgeries in the obstetrics and gynaecology department of Deen Dayal Upadhyay hospital over the stipulated period. Prevalence of ovarian masses was 13.7%. Most of the ovarian masses were prevalent in the reproductive age group i.e. 21-40 years of age group in the present study though malignant masses were commonest in post-menopausal age group in the present study. 2 out 11 malignant ovarian masses were in the age group of 10-20 years which were dysgerminoma and immature teratoma respectively. Intra-operative findings like presence of mural nodule, haemorrhage and necrosis, ascites, papillary excrescences and omental caking were also found to have strong correlation with malignancy.Conclusions: A detailed preoperative workup and a simple tool loke RMI can differentiate between benign and malignant masses pre-operatively especially in post-menopausal women.

Author(s):  
Michelle N. Fonseca ◽  
Madhavi J.

Background: Ovarian tumours can be seen at all stages of life but they differ in type, being mostly germ cell tumours in childhood, functional cysts in the reproductive age group (up to 45 years) and becoming increasingly malignant towards and after menopause. It also accounts for most prevalent cause of hospital admissions.Methods: This is a retrospective study conducted in the Department of Obstetrics and Gynaecology at a tertiary care hospital in Mumbai from August 2017 to August 2018. All patients with ovarian masses who were surgically managed were included in the study. The data of 30 patients was collected in excel sheet and analyzed by descriptive statistics.Results: Out of the 30 ovarian masses, 50 % were functional cysts, 46.6% were benign ovarian masses and 3.3% were borderline malignant. 46% of tumours were seen in the age group 21-30 years. More than 50 % tumours were seen in parous women. Most common presenting clinical symptom was pain in abdomen irrespective of the type of tumour. Most common complication was haemorrhage in the cyst. Laparoscopy was done in 4 patients and 26 required exploratory laparotomy. Most common surgery performed was unilateral cystectomy for functional ovarian cysts and benign ovarian tumours. Mucinous cystadenoma was the most common benign ovarian tumour, followed by dermoid cyst.Conclusions: Pre-operative diagnostic approach to a patient with ovarian mass includes careful history taking, thorough clinical examination, ultrasound and tumour marker assays in selected cases. Conservative surgery should be the goal to preserve fertility in young patients with ovarian tumours.


2021 ◽  
Vol 5 (2) ◽  
pp. 891-895
Author(s):  
Ahmed Hassan Abdelmoneim ◽  
Abdelwahed Abougazia ◽  
Amal Said Mahan ◽  
Amal Alobadli ◽  
Adham Darweesh

Ovarian tumours are commonly seen in reproductive age group in women. However, when they occur at extremes of age, the suspicion of malignancy increases. The detection of dermoid cyst at 56 years of age is uncommon, hence proper imaging with CA-125 level monitoring is essential. Awareness of benign tumours or rare possibility of malignant transformation in such age is mandatory for surveillance management or planning the surgical procedure.


Author(s):  
Nitin H Shah ◽  
Aditi Vivek Joshi ◽  
Sunita Mourya

An adnexal mass is a common entity in the reproductive age group. Ovarian masses form a majority of this condition. Tuberculosis is a disease commonly encountered in the Tropics and is endemic to India. Abdominopelvic affliction of this disease is common in women especially in the reproductive age groups. It may present with variety of non-specific clinical features and often poses an enormous diagnostic dilemma Author report one such case, presenting with a clinical impression of ovarian malignancy, however, was diagnosed to be a case of extensive pelvic tuberculosis on laparoscopy. Tissue biopsy was consistent with the finding of tuberculosis.


2020 ◽  
Vol 7 (1) ◽  
pp. 12-16
Author(s):  
Naheed Fatema ◽  
Zannatul Ferdosh ◽  
Sherajum Munira ◽  
KAM Mahbub Hasan ◽  
Nasim Iftekhar Mahmud ◽  
...  

Background: Management of ectopic pregnancy is very crucial issue for the survival of the patients. Objective: The purpose of the present study was to observe the surgical management and per-operative findings of women with ectopic pregnancy. Methodology: This cross-sectional study was carried out in the inpatient Department of Obstetrics and Gynaecology at Bangladesh Medical College Hospital, Dhaka, Bangladesh from January 2009 to December 2009 for a period of one (1) year. All clinically suspected cases of ectopic pregnancy within the reproductive age admitted in the department of Obstetrics and Gynaecology at the Bangladesh Medical College Hospital, Dhaka were included in the present study. In most of the cases, laparoscopy or laparotomy was done to confirm the diagnosis and manage the cases. Result: A total number of 48 cases of ectopic pregnancy women were recruited for this study. The highest number of ectopic pregnancy occurs in the ampulla of the fallopian tube which was 27(58.3%) cases. The right tube had been found to be affected more than the left which was 30(62.5%) cases and 18(37.5%) cases respectively. Most of the patients were presented with ruptured tubal pregnancy which was 30(62.5%) cases. Opposite tube was normal looking in 25(52.1%) cases. Unilateral salpingectomy and salpingectomy with contra lateral tubectomy were operated in 32(66.7%) cases and 10(20.8%) cases respectively. Conclusion: In conclusion most of the ectopic pregnancy is occurred in the site of ampulla of fallopian tube in right side which are mostly surgically managed by unilateral salpingectomy. Journal of Current and Advance Medical Research 2020;7(1): 12-16


Author(s):  
Madhusmita Choudhury ◽  
Monoj K. Deka ◽  
Shah A. Sheikh

Background: Ovarian malignancy is the second most common cancer of the female reproductive system and the leading cause of death from gynecologic malignancy. With increase in longevity, the incidence of epithelial ovarian cancer is increasing and its etiopathology remains unknown. A female’s risk at birth of having ovarian tumour sometime in her life is 6-7%. Two third of ovarian tumours occur in women of reproductive age group. The aim was to study the distribution of morphological pattern of benign, malignant, and nonneoplastic lesions of the ovary in different age groups and to determine the likelihood of bilateral involvement in different morphologic subtypes.Methods: A retrospective study from January 2018 to December 2020 was undertaken. A total of 210 surgical specimens were obtained. Detailed clinical information and radiological findings were recorded from the case sheets. Grossing of the surgical specimens was done in the pathology department, followed by histological examination.Results: Of 210 cases, benign cases were 140 (66.7%), malignant cases were 70 (33.3%). Surface epithelial tumors were most common (116/55.2%) followed by germ cell tumors (76, 36.1%) followed by others. Serous cystadenoma was commonest benign tumor (58, 41.4%). Serous adenocarinoma was commonest malignant tumor (19, 27.1%). Benign tumours were more common in the younger age group i.e. <40 years of age whereas malignant tumours were supervenes with increase in age. Most benign ovarian tumors (54, 38.6%) were seen between 31-40 years whereas most malignant tumors (24, 34.3%) were seen above 40 years. In 1st two decades, germ cell tumors were more common than other tumours.Conclusions: The prognosis and varying therapeutic strategies of ovarian tumours necessitate an accurate pathological evaluation. Histopathological study is still the gold standard in diagnosing most of these tumours. 


2020 ◽  
Vol 24 (4) ◽  
pp. 348-352
Author(s):  
Nusrat Noor ◽  
Rabiah Anwar ◽  
Rabia Akbar ◽  
Ghazala Sadaf ◽  
Khan M Yaqub

ABSTRACT Objective: To assess the effectiveness and enlist clinical factors, which may affect effectiveness of Pipelle sampling in diagnosing endometrial pathology in patients with abnormal uterine bleeding and Post-menopausal Bleeding. Study Design: ‘Analytical Cross-Sectional’ study. Place and duration: Gynecology Department at Combined Military Hospital Rawalpindi, in collaboration with Histo-Pathology Department, of six months duration i.e. from 1st  December 2019 to 31st May 2020. Patients and methods: 100 female patients of outpatient department with presenting complaints of either abnormal or post-menopausal bleeding were included in the study in the specified time frame. After informed written consent, Pipelle endometrial sampling was done on outpatient basis, and by consecutive sampling technique using lottery method, sample was sent for histopathological evaluation. Evaluated factors studied were:  indications for the procedure, age, parity, age of menarche. Results: Of the total patients evaluated, 91% (n=100) were non-malignant, while 4% (n=100) were malignant. Inadequate tissue was obtained in 5% samples. Most common histopathological findings among reproductive age group were Proliferative and Secretory phase endometrium 64% (n=100). While in Post-menopausal age group 4% (n=100) were Endometrial carcinoma on histopathology. Inadequate tissue samples 5% (n=100) were noted among the Post-menopausal group. 6% samples showed endometrial hyperplasia. Pipelle Endometrial Sampling had sensitivity and specificity, in diagnosing the endometrial pathologies is summarized in Table 3. Conclusion: Pipelle Endometrial Sampling is an effective, safe, simple and acceptable procedure for diagnosing endometrial pathology. It is cost effective requiring no anesthesia with high sensitivity and specificity for detecting endometrial pathology.  


Author(s):  
Dr. Chanchal Shrivastav ◽  
Dr. Akshay Berad ◽  
Dr. Paras Arvindbhai Parekh

According to WHO estimates, 16.7 million people around the globe die of cardiovascular disease each year. Economic transition, urbanization, industrialization and globalization bring about life style changes that promote heart disease. High blood pressure, high cholesterol and obesity are likely to become more prevalent in developing countries. Increased energy intake and sedentary lifestyle are also responsible for heart disease. The presence of one or more cardiovascular risk factors like high levels of TC, LDL, TG, glucose, insulin, BMI and a decreased HDL have been found to increase the progression of prehypertension to hypertension. Prehypertension increases the risk of MI and CAD. The present study was   undertaken to know serum lipid profile changes in reproductive and postmenopausal women. Total 60 Subjects of age group 20-45years (reproductive), 46-60years (postmenopausal) female volunteered for our study. During the study period, BMI, Lipid profile, parameters were recorded in all the subjects. In BMI, TC, LDL, VLDL, TG, is gradually increased, HDL is gradually decreased from reproductive age women to post menopausal women. Dyslipidemia occurs due to multifactorial reasons like physical activity, life style, diet, smoking, alcohol consumption, ethnicity and genetic makeup. Post-menopausal women are at increased risk of developing cardiovascular disease due to change in the lipid pattern and loss of cardioprotective effect of estrogen. Predicting the factors affecting the lipid profile in post-menopausal women, adopting strategies to control these mechanisms by modifying the relative risk factors during menopausal transition may improve the cardiovascular risk profile in these women. Keyword:  Lipid profile, Menopause, Reproductive age group.


2021 ◽  
pp. 73-76
Author(s):  
Sivakumar Vulava ◽  
P.R.D. Ganesh Basina ◽  
Aluri Anjanapriyanka ◽  
Uram. Arunajyothi

Aim and objectives: Ovarian tumours present with a wide variation in clinical presentation and morphological features. Ovaries apart from being a common sites of primary tumors, they are frequent sites for metastasis from organs like stomach, colon and breast. The present work has been undertaken to study the common morphologic and histological types of ovarian tumours in reproductive age group women. Materials and methods: A prospective study s study is conducted for a period of 3 years (August 2010 to September 2013). 100 cases of ovarian tumors in reproductive age women were selected for the present study. Age between 15 and 49 was taken as reproductive age. 100 cases of ovarian tumours in reproductive age women were selected for the present study. Age between 15 and 49 was taken as reproductive age. Out of the 100 cases 99 Results: were primary ovarian tumours, 1 was secondary / metastatic tumour. Out if the 99 primary tumours 94 were benign, 1 was borderline tumour and 4 were malignant tumours. Most tumours occurred in age between 30-40 years. Of the 99 primary tumours 85(90.4%) were surface epithelial tumours, 10 (10.6%) were germ cell tumours and 4 (4.2%) were sex-cord stromal tumours. 1 metastatic tumour, were noted. Benign ovarian tumours are more common than malignant tumours. Conclusion: Surface epithelial tumours are the most common type of all ovarian tumours. Surface epithelial tumours are the most common benign and malignant tumours in reproductive age group. The incidence, clinical presentation of the different types of ovarian tumours is extremely variable. Histopathology is still the gold standard in diagnosing most of ovarian tumours. Studying the macroscopic and microscopic features of different ovarian tumours will enable proper categorization into denite morphologic type.


2020 ◽  
pp. 35-36
Author(s):  
Anshu Baser ◽  
Bhoomika Jain ◽  
Sushil Kumar

Labial fusion is when the labia minora of the vulva fuse together. This most commonly occurs in prepubertal age group(0.6%-5%).(1) This condition rarely occurs in adults and even in adults it is seen in post menopausal women and may result in urinary incontinence.(2) It is extremely rare in women of reproductive age group and only a few cases have been reported so far.(3) We here report a case of a 25 year old female with asymptomatic labial fusion with no history of voiding difficulty, dyspareunia who presented to us at term in labour.


Author(s):  
Nishi Sood ◽  
Shyam Sunder Sud

Background: The objective of the present study was to observe the profile of infection in women with vaginal discharge.Methods: The present study was conducted between October 2013 and September2014. The respondents were females in reproductive age group (15-45 years) attending Obstetrics and Gynaecology OPD with history of vaginal discharge. After detailed clinical examination of the patient, pH was determined, and the posterior fornix was swabbed with a cotton tip applicator. Further a Whiff (amine) test done; wet mount was immediately prepared and examined. Another swab was sent for Gram’s stain and culture.Results: A total of 200 women with vaginal discharge were studied, of which 146 were diagnosed with pathogens. The most common form of infection was mixed infection which was diagnosed in 69 patients (34.5%). As a single pathogen, the next most common infection was Bacterial vaginosis seen in 43 patients (15.5%) and Trichomonas vaginalis seen in 3 patients (1.5%).Conclusions: The clinical manifestations of vaginits are diverse. By knowing the microbiology of the vaginal flora, we could come to the conclusion of the etiology of vaginitis.


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