scholarly journals Association of subclinical hypothyroidism and HbA1c levels in non-diabetic subjects attending rural tertiary care centre in central India

2017 ◽  
Vol 5 (8) ◽  
pp. 3345 ◽  
Author(s):  
Vidya Sagar Ram ◽  
Granth Kumar ◽  
Manoj Kumar ◽  
Vivek Kumar Verma ◽  
Dheeraj Kela ◽  
...  
Keyword(s):  
Subclinical Hypothyroidism ◽  
Tertiary Care ◽  
Elevated Serum ◽  
Control Group ◽  
Case Group ◽  
Diabetic Patients ◽  
Tertiary Care Centre ◽  
Hypothyroid Patients ◽  
Serum Tsh ◽  
Hba1c Levels

Background: Subclinical hypothyroidism is defined as an elevated serum TSH level and normal concentrations of free T3 (FT3), free T4 (FT4), T3 and T4. A positive association between thyroid and diabetes mellitus is well recognized but to study the effect of thyroid disorders on glucose metabolism in non-diabetic patients is an area for extensive research. Present study was planned to assess correlation between subclinical hypothyroidism and glycosylated haemoglobin levels in non-diabetic patients.Methods: A case-control study was conducted on total 209 subjects. 109 patients were allotted in case group and 100 in control group. Controls were relatives and friends of patients who were matched for age and sex. Comparison between the case and the control groups were made using Student’s t-test (unpaired) and Box and Whisker Plot and regression graph were presented for correlation between serum TSH and HbA1c.Results: It was found that there was a positive correlation between the levels of serum TSH (µU/L) and HbA1c (%) in all the participants of the study by Pearson’s correlation coefficient (r=0.35, p < 0.0001).Conclusions: HbA1c levels are increased in subclinical hypothyroid patients. The effects of the elevated levels of Serum TSH on the HbA1c must be considered when interpreting the HbA1c for the diagnosis of diabetes or pre-diabetes in the subclinical hypothyroid patients.

Relation between Uric Acid Levels and Subclinical Hypothyroidism in Diabetic Patients

2021 ◽  
Vol 21 ◽  
Author(s):  
Hosameldeen S. Shabana ◽  
Mahmoud Abdelrasheed Allam ◽  
Youssef Abdallah Nassar ◽  
Amgad Awad ◽  
Magdy M. Naguib ◽  
...  
Keyword(s):  
Uric Acid ◽  
Subclinical Hypothyroidism ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Control Group ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
And Control ◽  
Work Up ◽  
Hba1c Levels

Background and Aim: Subclinical hypothyroidism (SCH) is frequently seen in diabetic patients. Elevated levels of uric acid (UA) were also reported in diabetic patients. No study assessed the relation between SCH and UA levels in diabetic patients. We aimed to evaluate this relation and the association of both conditions with other clinical and laboratory parameters in diabetic patients. Subjects and Methods: This cross-sectional study included 100 T2DM patients in addition to 50 age and sex matched healthy controls. Diabetic patients comprised 50 patients with SCH and 50 euthyroid patients. All participants were subjected to careful history taking, thorough clinical examination and standard laboratory work up. The performed investigations included fasting and postprandial blood sugar, fasting insulin levels, HbA1c levels, thyroid hormones (FT3, FT4 and TSH), renal profile and serum UA. Results: Comparison between the studied groups regarding serum UA levels revealed significantly higher levels in the diabetic group (5.4 ± 1.9 versus 4.2 ± 1.0 mg/dl, p<0.001). SCH + DM patients had significantly higher UA levels in comparison to DM group (6.1 ± 1.8 versus 4.8 ± 1.7 mg/dl, p<0.001) and control group (6.1 ± 1.8 versus 4.2 ± 1.0 mg/dl, p<0.001). SCH + DM patients had significantly higher HbA1c levels (8.9 ± 1.1 versus 7.6 ± 1.3 %, p<0.001), HOMA-IR (3.9 ± 0.8 versus 2.8 ± 1.0, p<0.001) and UA levels (6.1 ± 1.8 versus 4.8 ± 1.7, p<0.001). Correlation analysis identified a significant direct correlation between serum UA and HOMA-IR in DM + SCH patients (r=0.4,p=0.004). In univariate analysis, presence of SCH [OR (95% CI): 2.57 (1.07-6.15), p=0.034] and nephropathy [OR (95% CI): 4.57 (1.77-11.8), p=0.002] were significant predictors of higher (upper tertile) UA in the studied patients. However, in multivariate analysis, only nephropathy [OR (95% CI): 4.25 (1.62-11.17), p=0.003] continued to be significant while SCH showed a marginal trend [OR (95% CI): 0.43 (0.17-1.08), p=0.073]. Conclusions: The present study suggests an association between SCH and increased UA levels in diabetic patients.

scholarly journals Effect of Iron Deficiency Anemia on HbA1c in Non-Diabetics

2020 ◽  
Vol 4 (1) ◽  
pp. 10-16
Author(s):  
R.K. Bansal ◽  
Y.R. Yadav ◽  
H.S. Kulkarni ◽  
Sonam ◽  
S. Garg ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Hba1c Level ◽  
Deficiency Anemia ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Diabetic Patients ◽  
Iron Deficient ◽  
Hba1c Levels

Background: Glycated hemoglobin A1c is a well-known indicator of glycemic control in diabetes patients. It comprises of 5% of total hemoglobin in non-diabetic patients as well. Iron Deficiency Anemia is most common cause of anemia, especially in this part of the world. So, we study the effects of Iron deficiency Anemia on HbA1c levels in non-diabetic adults to determine whether the HbA1c levels increase if any. Methods: A 100 non-diabetic adult patients with Iron Deficiency anemia admitted in various medicine wards and attending OPDs of J.L.N. Medical College and 100 healthy controls were enrolled after fulfilled inclusion and exclusion criteria. Detailed history of clinical examination and biochemical examination was performed including HbA1c. Results: Mean HbA1c level is more in iron deficient Anemic non-diabetic patients in comparison to non-Anemic non-diabetic patients. Mean HbA1c is 5.01 ± 0.41 in control group. While mean HbA1c level in case group is 6.11 ± 0.42. The difference is statistically significant (p value <.001). Conclusion: Iron deficiency Anemia is independent factor affecting HbA1c level in non diabetic patients & it should be interpreted carefully in all iron deficient anemic patients.  

scholarly journals Diagnosis of diabetes mellitus on the basis of HbA1c: Is this true in hypothyroidism also?

2016 ◽  
Vol 7 (6) ◽  
pp. 36-39
Author(s):  
Abhishek Singhai ◽  
Prakhar Kabra
Keyword(s):  
Subclinical Hypothyroidism ◽  
Tertiary Care ◽  
Fasting Blood Glucose ◽  
General Medicine ◽  
Overt Hypothyroidism ◽  
Medical Sciences ◽  
Tertiary Care Centre ◽  
Free T4 ◽  
Erroneous Diagnosis ◽  
Hypothyroid Patients

Background: Hypothyroidism may leads to hypoproliferative anemia. It is possible that this reduced erythropoiesis may result false elevation of HbA1c in some cases and further leading to an erroneous diagnosis of pre diabetes or diabetes.Aims and Objective: This study was planned to assess changes in HbA1c after initiation of thyroxine replacement in patients with subclinical and overt hypothyroidism.Settings and Design: This prospective study was conducted at Department of General Medicine of a tertiary care centre over one year.Methods and Material: 100 subjects were recruited for the study. Fasting blood glucose, serum creatinine, hemoglobin, HbA1c, reticulocyte count, serum free T4 and TSH estimation done in all subjects. Hypothyroid patients were started on thyroxine. After three months of documentation of euthyroidism, same investigations were repeated.Statistical analysis used: Statistical software, SPSS version 17.0 was used for analysis.Results:  After correction of hypothyroidism, TSH decreased from 92.3(±30.9) to 3.4±2.9 µIU/L and 12.2(±4.5) to 4.4±2.9 µIU/ml in overt hypothyroidism and subclinical hypothyroidism respectively. There was a statistically significant fall in the HbA1c (SD) from 5.9% (0.8) to 5.6% (0.6) and 6.0% (0.3) to 5.7% (0.3) following the correction of hypothyroidism in overt hypothyroidism and subclinical hypothyroidism respectively. However, there were no statistically significant changes in the fasting as well as postprandial blood glucose.Conclusions: Our study demonstrated that HbA1c values are falsely increased in patients with hypothyroidism. This falsely raised HbA1c became normal after thyroxine supplement.Asian Journal of Medical Sciences Vol.7(6) 2016 36-39

scholarly journals Correlation between Thyrotropin and Fasting Lipid Profile in Patients of Sub Clinical Hypothyroidism

2017 ◽  
Vol 23 (2) ◽  
Author(s):  
Syed Mohammad Zubair ◽  
Farhat Ijaz ◽  
Rana Khurram Aftab
Keyword(s):  
Lipid Profile ◽  
Subclinical Hypothyroidism ◽  
Tertiary Care ◽  
Serum Triglyceride ◽  
The Body ◽  
Whole Body ◽  
Control Group ◽  
Blood Collection ◽  
Case Group ◽  
Cross Sectional

AbstractA controversy exists regarding the association between subclinical hypothyroidism (SCH) and dyslipidemia. Moreover, studies on lipid ratios in SCH are rare, particularly in Asian Countries. The study also aims to find out whether any correlation exists between serum TSH levels and fasting lipid levels, which would indirectly affect morbidity and mortality.Methods:  The study was conducted at Physiology department, KEMU and Centre for Nuclear Studies KEMU & Mayo Hospital, Lahore which is a tertiary-care center. It was a cross-sectional study carried out over a period of 6 months. Control group consisted of 50 euthyroid persons taken from a population coming for whole-body health checkup. Case group consisted of 50 patients with SCH. Confounding variables were removed. Fasting blood samples were taken in a plain gel vaccutainer tube with an aseptic blood collection technique. The samples were centrifuged within 1 h at 3000 rpm for 5 min. These wereprocessed to obtain serum for the estimation of serum lipid profile and Thyrotropin (TSH) hormone level.Results:  The study examined the link between Thyrotropin levels and fasting lipid profile in patients of SCH versus euthyroid normal controls in a cross sectional adult population over a period of six months. Patients with SCH had significantly lower HDL-C, as compared to Controls. The Lipid profiles were each categorized and mean Thyrotropin levels were higher in subjects in the dyslipidemic sub-class than subjects in normal sub-class. Thyrotropin was positively asso-ciated with serum Triglyceride and negatively associated with HDL-C in cases of SCH. Thyrotropin is also positively associated with Total Cholesterol (TC) along with VLDL-C and LDL-C. In the Euthyroid (Control Group) population, Thyrotropin was positively associated with TC.Conclusion:  To conclude, Serum Thyrotropin was correlated with dyslipidemia in SCH and euthyroid subjects. In simple words, when Thyrotropin (TSH) increases upto 10 mIU/L the signs and symptoms of Hypothyroidism are not manifested, but chemical changes start to take place in the body, and the lipid metabolism is starting to take its toll. In SCH patients, TC, Triglyceride, LDL-C, HDL-C, start to rise as compared to normal euthyroid control groups. Thus there is a positive correlation between lipids and Thyrotropin, less HDL, which exhibited negative correlation in SCH subjects.AbstractA controversy exists regarding the association between subclinical hypothyroidism (SCH) and dyslipidemia. Moreover, studies on lipid ratios in SCH are rare, particularly in Asian Countries. The study also aims to find out whether any correlation exists between serum TSH levels and fasting lipid levels, which would indirectly affect morbidity and mortality.Methods:  The study was conducted at Physiology department, KEMU and Centre for Nuclear Studies KEMU & Mayo Hospital, Lahore which is a tertiary-care center. It was a cross-sectional study carried out over a period of 6 months. Control group consisted of 50 euthyroid persons taken from a population coming for whole-body health checkup. Case group consisted of 50 patients with SCH. Confounding variables were removed. Fasting blood samples were taken in a plain gel vaccutainer tube with an aseptic blood collection technique. The samples were centrifuged within 1 h at 3000 rpm for 5 min. These wereprocessed to obtain serum for the estimation of serum lipid profile and Thyrotropin (TSH) hormone level.Results:  The study examined the link between Thyrotropin levels and fasting lipid profile in patients of SCH versus euthyroid normal controls in a cross sectional adult population over a period of six months. Patients with SCH had significantly lower HDL-C, as compared to Controls. The Lipid profiles were each categorized and mean Thyrotropin levels were higher in subjects in the dyslipidemic sub-class than subjects in normal sub-class. Thyrotropin was positively asso-ciated with serum Triglyceride and negatively associated with HDL-C in cases of SCH. Thyrotropin is also positively associated with Total Cholesterol (TC) along with VLDL-C and LDL-C. In the Euthyroid (Control Group) population, Thyrotropin was positively associated with TC.Conclusion:  To conclude, Serum Thyrotropin was correlated with dyslipidemia in SCH and euthyroid subjects. In simple words, when Thyrotropin (TSH) increases upto 10 mIU/L the signs and symptoms of Hypothyroidism are not manifested, but chemical changes start to take place in the body, and the lipid metabolism is starting to take its toll. In SCH patients, TC, Triglyceride, LDL-C, HDL-C, start to rise as compared to normal euthyroid control groups. Thus there is a positive correlation between lipids and Thyrotropin, less HDL, which exhibited negative correlation in SCH subjects.Keywords:  Dyslipidemia, lipid profile, subclinical hypothyroidism.

scholarly journals Status of serum anti-mullerian hormone and lipid profile in polycystic ovarian syndrome: a cross-sectional study at tertiary care centre of central India

2018 ◽  
Vol 6 (4) ◽  
pp. 1327
Author(s):  
Sangita Paneri ◽  
Shakti Suslade ◽  
Angurbala Bafna ◽  
Jayshee Shreedhar ◽  
P. Dey Sarkar ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Polycystic Ovarian Syndrome ◽  
Ovarian Follicle ◽  
Tertiary Care ◽  
Control Group ◽  
Case Group ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Female Population ◽  
Ovarian Syndrome

Background: Polycystic ovarian syndrome (PCOS) is the most common cause of chronic anovulation in young women and affects 5 to 10 % of the female population. Anti-Mullerian Hormone (AMH) level indicate the quantity of the ovarian follicle pool and may be a useful marker of ovarian reserves. In order to establish the pattern of change in serum AMH level and its contribution in alteration of lipid metabolism and PCOS related complications the present study was planned.Methods: Study was carried out in M.G.M. medical college, Govt Holker College and K. R. G’s Blessed mom centre from June -2016 to December -2017. The study population consisted total 50 women subjects among them 25 women suffering from PCOS aged between 18 to 35-year taken as case group and 25 age matched healthy women taken as control group. Fasting blood sample was collected from each subject and analyzed for AMH level and Lipid profile level.Results: Results revealed that significantly increased serum AMH, cholesterol, triglycerides, LDL, VLDL levels and significantly decreased HDL levels were observed in PCOS cases when compare to control subjects.Conclusions: Study concluded elevated AMH level leads to increase risk of polycystic ovarian syndrome and PCOS associated hyperlipidemia and other complications.

scholarly journals Impact of High-normal Serum TSH with First Trimester Pregnancy Loss: A Case-control Study in Tertiary Care Hospitals in Bangladesh

2018 ◽  
Vol 1 (1) ◽  
pp. 29-35
Author(s):  
Yisrat Jahan ◽  
M Anwar Hussain ◽  
Rezaul Karim Kazal ◽  
Mohammad Akhteruzzaman ◽  
Rifat Jahan
Keyword(s):  
Pregnancy Loss ◽  
Tertiary Care ◽  
First Trimester ◽  
Normal Serum ◽  
Control Group ◽  
Case Group ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy ◽  
Tertiary Care Hospitals ◽  
Serum Tsh

The relationship between existing thyroid autoimmunity and the probability of spontaneous abortion has been the subject of a number of studies. In this study, we evaluate the impact of `high normal' serum TSH levels (2.5-5.0 mlU/L) on first trimester pregnancy loss in anti-TPO Ab negative women in Bangladesh. Specifically, we wanted to know the average serum TSH levels for women who had a miscarriage (case group) and who did not have a miscarriage (control group) during the first trimester of pregnancy. Unmatched case-control study involving 119 women in their first trimester was conducted during July 2011 to June 2012 in three tertiary care hospitals in Bangladesh. We found average TSH level for the control group (1.42$\pm$0.86 mlU/L) to be lower than the average for the case group (1.74$\pm$1.15 mlU/L). However, we did not find statistically significant association between the serum TSH level and first-trimester pregnancy loss. The findings of this study will provide a baseline for future studies on this topic involving Bangladeshi women. In addition, our study adds to the growing discussion on redefining the lower limit for the `high normal' serum TSH level among the anti-TPO Ab negative women.

Carnitine deficiency in chronic obstructive lung disease: A study in a tertiary care centre

2021 ◽  
Vol 6 (3) ◽  
pp. 183-187
Author(s):  
M Ravindranath ◽  
C H Raju
Keyword(s):  
Lung Disease ◽  
Obstructive Lung Disease ◽  
Tertiary Care ◽  
Chronic Obstructive Lung Disease ◽  
Carnitine Deficiency ◽  
Control Group ◽  
Chronic Obstructive ◽  
X Rays ◽  
Tertiary Care Centre ◽  
Regular Diet

Chronic Obstructive Lung Disease (COPD) is a condition where there is poor airflow to the lungs and over a period of time this condition worsen, resulting in severe morbidity. L-carnitine (LC) is a soluble qaurtenary amine and is essential for the tissues and lung tone to function normally. This study was therefore find out the association of L-carnitine in patients with chronic Obstructive Pulmonary Disease. 75 patients who came to the Department of Pulmonology of either sex between 40 to 75 years with confirmed COPD were included into patients group and 75 healthy patients were included into the control group. Blood was collected for Fasting blood sugar, AST, ALP, ALT, Urea, Creatinine, Albumin, pre-albumin, iron , magnesium, sodium, phosphorous, calcium, Acylcarnitines, total and free carnitine levels. X-rays were taken and pulmonary function test was done for all the patients. The mean age of the patients in our study was 62.53 and 61.86 years among the patients and controls respectively. Among the controls the Ph and Fe levels were 3.1 ± 0.9mmol/L and 21.69 ± 3.19 mcg/dL respectively and among the patients the same levels were 2.6 ± 1.9mmol/L and 43.82 ± 8.22mcg/dL respectively. The albumin and the prealbumin in the patients were significantly lower in the patients with 21.81 ± 2.88 and 23.53 ±2.58 mg/dL and in controls they were 32.61 ±3.87 and 26.87 ± 1.93 mg/dL respectively. There was a considerable carnitine deficiencies in COPD patients when compared to the controls and since carnitine can be found in regular diet, people can be educated to have a proper intake of foods containing carnitine in their regular diet.

Awareness of Complications in Diabetic Patients - Study in a Tertiary Care Centre in Kerala

2021 ◽  
Vol 8 (37) ◽  
pp. 3334-3338
Author(s):  
Satish Kumar
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Tertiary Care Centre ◽  
Type 2 Diabetic Patients ◽  
Complications Of Diabetes ◽  
Type 2 Diabetic

BACKGROUND Type 2 diabetes mellitus is common in the Indian population and awareness regarding the disease and its complications is low among the patients with diabetes. There is lack of studies regarding awareness of complications of diabetes among type 2 diabetic patients. The purpose of this study was to assess the awareness of diabetic complications among type 2 diabetic patients. METHODS This is an institutional based observational study. The sample comprised of 150 adult patients with type 2 diabetes mellitus who underwent treatment in the Department of Medicine, Medical College Kottayam and the patient’s age ranged from 18 - 77 years. RESULTS Majority of patients were in the age group 38 to 57 and the sample comprised of 56 % males and 44 % female patients. Out of 150 patients involved in the study, 120 patients (80 %) were aware of the complications of diabetes mellitus. Among the male patients, 70 (83.33 %) and among females, 50 (75.75 %) were aware of the complications in diabetes. In the study sample, 92 (61.33 %) were aware of the foot problems, 120 patients (80 %) were aware of renal complications, 91 patients were aware regarding eye problems of diabetes, 38 (25.33 %) regarding development of hypertension, 62 (41.33 %) regarding heart attack, 42 (28 %) patients were aware regarding development of stroke and 78 patients (52 %) had awareness regarding occurrence of recurrent infections. CONCLUSIONS Awareness regarding diabetes and its complications is fairly good among the diabetic patients in Kerala. Awareness regarding all complications of diabetes was higher among males than females. Providing awareness to type 2 diabetic patients by various educational programs may be of further help to prevent complications and to decrease the mortality and morbidity in type 2 diabetes patients. KEYWORDS Awareness, Diabetes

scholarly journals Thyroid status and Treatment Response of Hypothyroid Infertile Women in Tertiary Care Center of Bangladesh

2017 ◽  
Vol 31 (2) ◽  
pp. 86-89
Author(s):  
Farzana Deeba ◽  
Parveen Fatima ◽  
Jesmine Banu ◽  
Shakeela Ishrat ◽  
Nurjahan Begum ◽  
...  
Keyword(s):  
Subclinical Hypothyroidism ◽  
Early Stage ◽  
Care Center ◽  
Tertiary Care ◽  
Target Population ◽  
Fertility Treatment ◽  
Tertiary Care Centre ◽  
Infertile Women ◽  
The Mean ◽  
Tsh Levels

Objective(s): Aim of this study was to find out the prevalence of hypothyroidism in infertile women as well as to assess their response to treatment.Materials and methods: This descriptive study was conducted in Infertility unit of Department of Obstetrics and Gynecology, Bangabandhu Sheikh Mujib Medical University, Bangladesh, a tertiary care centre from January 2014 to December 2014. Four hundred women who visited infertility clinic of the department for fertility treatment were the target population for this study. Routine investigations such as CBC, Blood sugar 2 hours postparandial or GTT, TSH and Prolactin was done. Subclinical hypothyroidism was diagnosed when there was increased TSH and normal FT4. Hypothyroid patients were given Levothyroxin depending upon TSH levels and continued until end of the study. Patients were followed up for six months even if pregnancy was attained.Results: Out of 400 women 55% were primary and 45% were secondary subfertility. Mean duration of infertility was 4.5 ± 1.2 years. Ninety two (23%) patients were hypothyroid. Among them 66 (16.5%) were subclinical hypothyroid and 26 (6.5%) were frank hypothyroid. The mean TSH levels were 7.34 ± 2.13 ìIU/ml, and the mean PRL levels were 52.46 ± 11.17 ng/ml. Out of 92 infertile women diagnosed as hypothyroidism 75 (81.52%) women conceived after treatment with drugs for hypothyroidism (dose depending upon severity of hypothyroidism, i.e. TSH levels). More than 90% women had regular ovulation for consecutive three cycles after initiation of treatment.Conclusion: The normal TSH levels are the pre-requisite for fertilization. The decision to initiate thyroid replacement therapy in both clinical and subclinical hypothyroidism at early stage is justified in infertile women.Bangladesh J Obstet Gynaecol, 2016; Vol. 31(2) : 86-89

scholarly journals A prospective case control study of the effects of oligohydramnios on fetomaternal outcome in mothers with term pregnancy in a rural medical college

2018 ◽  
Vol 7 (11) ◽  
pp. 4706
Author(s):  
Dipak Mandi ◽  
Sayantan Sen ◽  
Vasundhara Goswami
Keyword(s):  
Demographic Data ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Perinatal Complications ◽  
Medical College ◽  
Increased Risk ◽  
Nicu Admission

Background: The aim of the current study was to assess the fetomaternal effects of oligohydramnios on term pregnancies in a rural tertiary care setup.Methods: A perspective case control hospital-based trial was conducted at Burdwan Medical College and Hospital for a period of one year. Pregnancies at term (37-42 weeks) were included in the study. 103 patients with sonographically diagnosed oligohydramnios were included in the case group. The control group comprised of 103 mothers at term with normal liquor volume. Demographic data and fetomaternal outcome parameters were assessed and compared.Results: There was increased incidence of fetal and perinatal complications including low birth weight, birth asphyxia and NICU admission. There were more perinatal deaths in the case group compared to the control group. Induction of labour, operative delivery, meconium stained liquor and incidence of preeclampsia were also increased in mothers with low AFI.Conclusions: Oligohydramnios is associated with an increased risk of labour and perinatal complications. Adequate antenatal surveillance and intranatal monitoring coupled with correction of underly-ing factors is the mainstay of management.

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