scholarly journals The study of prevalence of metabolic syndrome in the first degree relatives of type 2 diabetes mellitus patients

2018 ◽  
Vol 6 (9) ◽  
pp. 3042
Author(s):  
Mahim Mittal ◽  
Himanshu Gupta ◽  
Deepshikha .
Keyword(s):  
Metabolic Syndrome ◽  
Central Obesity ◽  
Research Work ◽  
Cross Sectional Study ◽  
Biochemical Tests ◽  
Cross Sectional ◽  
First Degree Relatives ◽  
Increased Risk ◽  
New Onset

Background: Metabolic syndrome (MetS) is associated with higher incidence of new onset DM. First degree relatives (FDR) of T2DM patients also have an increased risk of new onset DM due to common genetic factors that can lead to obesity and dyslipidemia. Objectives of research work was to study the prevalence of MetS in FDR of T2DM patients.Methods: Cross-sectional study of FDR of T2DM patients. MetS defined by both IDF and NCEP-ATPIII criteria. All subjects underwent necessary biochemical tests, a detailed history in a pre defined proforma was taken and clinical examination was done as per protocol.Results: Mean age was 43.61±11.7 years. Prevalence of MetS was 35% by IDF and 25% by NCEP-ATPIII. According to IDF criteria, the most prevalent risk factors among FDR were central obesity and hypertension. Prevalence of MetS was higher in urban, sedentary and obese population.Conclusions: Prevalence of MetS is more in FDR of T2DM than that reported in the general population. Central obesity is the most prevalent risk factor. Targeted lifestyle intervention in this population may help prevent the development of MetS and T2DM.

scholarly journals Eating Competence Is Associated with Lower Prevalence of Obesity and Better Insulin Sensitivity in Finnish Adults with Increased Risk for Type 2 Diabetes: The StopDia Study

Nutrients ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 104 ◽  
Author(s):  
Tanja Tilles-Tirkkonen ◽  
Kirsikka Aittola ◽  
Reija Männikkö ◽  
Pilvikki Absetz ◽  
Marjukka Kolehmainen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Insulin Sensitivity ◽  
Cross Sectional Study ◽  
Healthy Diet ◽  
Lower Prevalence ◽  
Cross Sectional ◽  
Increased Risk ◽  
Eating Competence

A healthy diet prevents type 2 diabetes but is often difficult to adhere to. This cross-sectional study aimed to investigate whether eating competence is associated with diet or risk factors and prevalence of type 2 diabetes in individuals screened for type 2 diabetes risk. Eating competence is an indicator of food acceptance, positive attitudes, internal regulation and contextual skills related to food and eating. In total, 3147 Finnish adults aged 18–74 at an increased risk for type 2 diabetes identified via online risk screening participated in the baseline examinations of the Stop Diabetes (StopDia) study. The participants filled out the digital questionnaire on food intake, physical activity and sleep, and the Satter Eating Competence Inventory 2.0TM (ecSI 2.0TM). In addition, anthropometric and laboratory measurements were performed at primary healthcare centres. Eating competent individuals (37%, classified by ecSI 2.0TM) had a better quality of diet (p < 0.05 for all). Additionally, eating competence was associated with a lower prevalence of previously undiagnosed type 2 diabetes, abdominal obesity, metabolic syndrome and hypertriglyceridaemia, and with better insulin sensitivity (p < 0.05 for all). However, these associations, except for metabolic syndrome, were at least partly mediated by body mass index. Eating competence is associated with a healthy diet and could, thus, in the long term, support the prevention of type 2 diabetes.

scholarly journals Prevalence of Metabolic Syndrome in Patients With Type 2 Diabetes Mellitus in a Tertiary Care Hospital

2019 ◽  
Vol 18 (2) ◽  
pp. 36-41
Author(s):  
Dipesh Shakya ◽  
Vijay KC
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Central Obesity ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Three Components

Introduction: Diabetes mellitus is associated with various metabolic disorders, which leads to the progression of the disease and its complications. The aim of the study is to find out prevalence of metabolic syndrome and its association with the components and demographic variables. Methods: This cross-sectional study was conducted among diabetes mellitus patients at a Tertiary level teaching hospital over a period of one year (April 2015 to March 2016). The study involved the use of a questionnaire to obtain information on diabetes by performing anthropometric measurements and corroborating it with respective blood samples collected for the measurement of biochemical parameters, fasting blood glucose and lipid profile. Metabolic syndrome was defined according to the current guidelines, revised in 2005 by the National Heart, Lung and Blood Institute and the American Heart Association. Statistical Package for the Social Sciences Version 20 was used as a tool for statistical analysis. Results: This cross-sectional study involved 200 type 2 diabetes mellitus patients. The prevalence of metabolic syndrome was 71% in the studied Nepalese population. Central obesity (77.5%) and hypertension (76.8%) were the commonest risk factors. It was followed by dyslipidemia among which 65.5% had high triglyceride level and 50.7% had low level of high density lipoprotein cholesterol. Higher prevalence of metabolic syndrome was seen in male patients with type 2 diabetes which accounted for 84 (73.3%). Three components of metabolic syndrome were seen among 70 (35%) and five components among 29 (14.5%) patients. Among the patients who were studied, the age group 45 to 54, 55 to 64 and 65 to 74 years had 14 (20%), 20 (28.6%) and 19 (27.1%) of more than three components of metabolic syndrome respectively. Conclusions: The prevalence of metabolic syndrome was 71% among the patients with type 2 diabetes, where high prevalence was seen among males. In our study central obesity and hypertension along with increasing age were the most common component causing metabolic syndrome.  

scholarly journals Low Carbohydrate Diet Score and the Risk of Metabolic Syndrome in Chinese Adults

2021 ◽  
Author(s):  
Baofu Guo ◽  
Xiaocheng Li ◽  
Di Jin ◽  
Hui Zuo ◽  
Fangyan Zhu ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Fatty Acids ◽  
Central Obesity ◽  
Monounsaturated Fatty Acids ◽  
Cross Sectional Study ◽  
Carbohydrate Diet ◽  
Cross Sectional ◽  
Low Carbohydrate Diet ◽  
Increased Risk ◽  
Low Carbohydrate

Abstract Previous studies on estimated associations between low carbohydrate diet (LCD) score and metabolic syndrome (MetS) are inconsistent. We aim to assess the association between LCD score and MetS in a Chinese population. A multi-stage random sampling method was applied and a total of 1993 participants aged more than 18 years from a cross-sectional study in Nanjing, Jiangsu Province were accessed. Dietary intake was evaluated using a consecutive 3-d, 24-h dietary recall combined with the condiments weighing method.LCD scores, including usual, animal-based, and plant-based LCD scores, were calculated based on energy, carbohydrate, fat, and protein intake by sex. In multivariate regression analyses adjusted for age, total energy intake and other potential confounders, the usual LCD score significantly increased risk of MetS in men [the highest quartile vs. lowest quartile: odds ratio (OR): 1.75; 95% confidence interval (CI): 1.07–2.87, Pfor trend < 0.05]. Furthermore, a significant trend was found between plant-based LCD score and the MetS in men (Pfor trend < 0.05). Among the components of the MetS, higher usual LCD score increased the risk of central obesity, hyperglycemia and hypertriglyceridemia in men, meanwhile animal-based LCD score was positively associated with the risk of central obesity, and plant-based LCD score was positively associated with the risk of hyperglycemia in men. Our results reveal that low carbohydrate and excessive fat diet (even monounsaturated fatty acids and polyunsaturated fatty acids), may increase the risk of MetS and Chinese male is more sensitive to the transition of dietary composition from high carbohydrate to high fat than Chinese female. Further studies are warranted.

Metabolic Syndrome During Menopause

2019 ◽  
Vol 17 (6) ◽  
pp. 595-603 ◽  
Author(s):  
Sezcan Mumusoglu ◽  
Bulent Okan Yildiz
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Central Obesity ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Natural Menopause ◽  
The Metabolic Syndrome ◽  
Increased Risk ◽  
Aging Women

The metabolic syndrome (MetS) comprises individual components including central obesity, insulin resistance, dyslipidaemia and hypertension and it is associated with an increased risk of cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). The menopause per se increases the incidence of MetS in aging women. The effect(s) of menopause on individual components of MetS include: i) increasing central obesity with changes in the fat tissue distribution, ii) potential increase in insulin resistance, iii) changes in serum lipid concentrations, which seem to be associated with increasing weight rather than menopause itself, and, iv) an association between menopause and hypertension, although available data are inconclusive. With regard to the consequences of MetS during menopause, there is no consistent data supporting a causal relationship between menopause and CVD. However, concomitant MetS during menopause appears to increase the risk of CVD. Furthermore, despite the data supporting the association between early menopause and increased risk of T2DM, the association between natural menopause itself and risk of T2DM is not evident. However, the presence and the severity of MetS appears to be associated with an increased risk of T2DM. Although the mechanism is not clear, surgical menopause is strongly linked with a higher incidence of MetS. Interestingly, women with polycystic ovary syndrome (PCOS) have an increased risk of MetS during their reproductive years; however, with menopausal transition, the risk of MetS becomes similar to that of non-PCOS women.

scholarly journals Association of breastfeeding and risk of metabolic syndrome and its components in postmenopausal parous women: Korea national health and nutrition examination survey (2010 ~ 2016)

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Jusuk Lee ◽  
Taehong Kim
Keyword(s):  
Metabolic Syndrome ◽  
Laboratory Data ◽  
Multivariate Logistic Regression Analysis ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Korean Women ◽  
Cross Sectional ◽  
Increased Risk ◽  
Nationally Representative ◽  
Study Participants

Abstract Background Understanding the relationship between breastfeeding (BF) and metabolic syndrome (Mets) is important for maternal long-term health benefits and disease prevention. This study aimed to examine the association between BF and Mets and its components among postmenopausal parous Korean women. Methods This cross-sectional study on 10,356 Korean women used nationally representative data from the KNHANES from 2010 to 2016. Anthropometric, laboratory data and manual BP were measured. A multivariate logistic regression analysis was conducted to examine the association of BF with Mets and its components after adjusting for potential confounding variables. A p-value < 0.05 was to be considered statistically significant. Results Mets was present in 42% of the study participants. The BF group had low household income and education level. The prevalence of Mets in the BF group was higher than that in the non-BF group (42.69% vs. 34.76%, p <  0.001). BF was associated with increased risk of Mets (odds ratio [OR]: 1.4, 95% confidence interval [CI]: 1.18–1.65, p <  0.001). The BF group was at higher risks for diabetes (OR: 1.5, 95%CI: 1.14–1.98), hypertension (OR: 1.32, 95%CI: 1.03–1.68), hypertriglyceridemia (OR: 1.42, 95%CI: 1.02–1.99) and low high-density lipoprotein cholesterol (OR: 1.32, 95%CI: 1.06–1.65). Conclusion In this study, BF did not affect decreasing the prevalence of Mets and its components.

scholarly journals Prevalence of Metabolic Syndrome (MetS) and Determinants Among Obese Teachers in Makassar, Indonesia

2020 ◽  
Vol 18 (2) ◽  
Author(s):  
Nurzakiah Hasan MKM ◽  
Veni Hadju ◽  
Nurhaedar Jafar ◽  
Ridwan M. Thaha
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Sitting Time ◽  
Moderate Physical Activity ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Increased Risk ◽  
Study Population

Metabolic Syndrome (MetS) is related to the increased risk of non-communicable diseases (NCDs). Teacher profession is an adult group with various risks of NCDs. This study aims to assess the determinants of the MetS in teachers with central obesity. Material and Methods: The study was conducted in Makassar, South Sulawesi, Indonesia with cross- sectional study design on 12 secondary schools. The number of samples in this study was 129 teachers. The prevalence of the MetS was determined using criteria from the Joint Interim Statement, while physical activity and sitting time were measured using the International Physical Activity Questionnaire (IPAQ). Results: Respondents in our study were mostly women (78.3%) with an average age of 49.8 years. The prevalence of the MetS in our study population was 39.5%. The prevalence of the Mets was higher in Buginese ethnic (70.6%), respondents with more income (56.9%), bachelor degree (80.4%), married (98%), family history of diabetes mellitus, obesity, hypertension and heart diseases (52.9%), and moderate physical activity (37.3%). There was a significant relationship between sitting time 4 hours; p=0.004), parameters of Mets (p<0.001), LDL (p=0.026), and LDL/HDL ratio (p<0.001) with the Mets. Conclusions: The prevalence of the Mets is high among obese teachers in our study population. Sitting time was an important determinant for MetS among obese teachers.

scholarly journals Clinical relevance of reporting fatty liver on ultrasound in asymptomatic patients during routine health checkups

2018 ◽  
Vol 46 (11) ◽  
pp. 4447-4454 ◽  
Author(s):  
Ajit Ramakant Mahale ◽  
Sonali Dattatray Prabhu ◽  
Muthiah Nachiappan ◽  
Merwyn Fernandes ◽  
Sonali Ullal
Keyword(s):  
Metabolic Syndrome ◽  
Early Detection ◽  
Fatty Liver ◽  
Clinical Relevance ◽  
Glycosylated Hemoglobin ◽  
Lipoprotein Metabolism ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Asymptomatic Patients

Objective Ultrasonography is an efficient technique for detecting fatty liver. Its sensitivity and specificity in detecting moderate to severe fatty liver are comparable to those of histology. Fatty liver is associated with abnormal lipid and lipoprotein metabolism and insulin resistance, metabolic syndrome, cardiovascular/renal disease, type 2 diabetes, and other conditions. This study was performed to compare the serum lipid profiles and serum glutamic pyruvic transaminase (GPT), glutamic oxaloacetic transaminase (GOT), and glycosylated hemoglobin (HbA1c) levels in patients diagnosed with fatty liver on ultrasonography versus controls without fatty liver and evaluate the clinical relevance of an ultrasound diagnosis of fatty liver in routine health checkups. Methods This hospital-based cross-sectional study included 390 patients who underwent health checkups; 226 were diagnosed with fatty liver (cases) and 164 were not (controls). The lipid profile, serum GOT and GPT levels, and HbA1c level were compared between the cases and controls. Results The cases had considerably higher levels of lipids, liver enzymes (serum GOT and GPT), and HbA1c than controls. Conclusion Ultrasonography is a noninvasive simple tool for early detection of fatty liver in asymptomatic patients and can help clinicians achieve early detection of metabolic syndrome.

scholarly journals Follicle-Stimulating Hormone Positively Associates with Metabolic Factors in Perimenopausal Women

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Chen Zhang ◽  
Meng Zhao ◽  
Zhengyang Li ◽  
Yongfeng Song
Keyword(s):  
Metabolic Syndrome ◽  
Central Obesity ◽  
Follicle Stimulating Hormone ◽  
Premenopausal Women ◽  
Single Center ◽  
Metabolic Factors ◽  
Cross Sectional ◽  
Increased Risk ◽  
Perimenopausal Women ◽  
Cv Disease

Objective. Menopause is associated with the increased risk of metabolic syndrome (MetS) and cardiovascular (CV) disease. Most studies have focused the postmenopausal women and the relationships among estrogen, androgen, and Mets risk. The main aim of the study was to investigate the Mets risk in perimenopausal women and whether the variation of FSH is associated with metabolic factors. Methods. A single-center cross-sectional retrospective analysis including 154 premenopausal women and 124 perimenopausal women was performed. Results. The prevalence of Mets in the perimenopausal group was much higher than the premenopausal group (49.19% vs. 35.71%, p = 0.023 ). The prevalence of central obesity and NAFLD also increased in the perimenopausal group than in the premenopausal group. We grouped the population by FSH tertiles; compared with women in the lowest tertile, women in the highest tertile had higher age, WC, serum TC, LDL-C, AST, ALT, and creatine levels. The prevalence of hypertriglyceridemia, raised BP and Mets also increased in the highest tertile group. Further, we subdivided the perimenopausal women according to FSH tertiles. Compared with perimenopausal women in the lowest tertile, the prevalence of raised BP significantly increased in the highest tertile. Conclusions. The risk of Mets increased in perimenopausal females than in premenopausal women. And a higher FSH level was associated with higher WC, TG, BPs, and the risk of Mets in perimenopausal women. Elevated FSH level appears to be a risk factor of MetS biomarkers in perimenopausal women.

scholarly journals Magnitude of metabolic syndrome and its associated factors among patients with type 2 diabetes mellitus in Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia: a cross sectional study

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Gebreamlak Gebremedhn Gebremeskel ◽  
Kalayou Kidanu Berhe ◽  
Desta Siyoum Belay ◽  
Berihu Hailu Kidanu ◽  
Assefa Iyasu Negash ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Overweight And Obesity ◽  
Sectional Study ◽  
Cross Sectional ◽  
Specialized Hospital

Abstract Objective The objective of this study was to assess magnitude of metabolic syndrome and its associated factors among type 2 diabetes mellitus patients in Ayder Comprehensive Specialized Hospital. A hospital based cross sectional study design was used. Binary logistic regression model was used. Result A total of 419 respondents (208 males and 211 females) were enrolled; the mean age was 56.39 (SD 10.18), 51.1% of the respondents had metabolic syndrome according to international diabetes federation. Sex and age were statistically associated with metabolic syndrome with [AOR (95% CI) 1.93 (1.057, 3.533) and 1.04 (1.012, 1.072)] respectively. Regular physical exercise, overweight and obesity were statistically associated with metabolic syndrome with [AOR (95% CI) 1.84 (1.002, 3.362), 2.68 (1.518, 4.747) and 3.55 (1.254, 10.074)] respectively. To conclude, Magnitude of metabolic syndrome was high. The associated factors for metabolic syndrome are physical inactivity, inadequate intake of fruits, family history, overweight, and obesity.

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